def __init__(self, parent=None, signalManager = None):
OWWidget.__init__(self, parent, signalManager, 'Process Chip Data')
self.callbackDeposit = []
self.inputs = [("Structured Data", DataFiles, self.chipdata)]
self.outputs = [("Structured Data", DataFiles)]
self.chipdata = None; self.datasets = None
self.std = [("No preprocessing", None),
("Array-based standardization", chipstat.standardize_arrays),
("Gene-based standardization", chipstat.standardize_genes),
("First array-, then gene-based standardization", lambda e,r: chipstat.standardize_genes(chipstat.standardize_arrays(e,r),r)),
("First gene-, then array-based standardization", lambda e,r: chipstat.standardize_arrays(chipstat.standardize_genes(e,r),r))]
# Settings
self.data = None
self.preStdMethod = 0; self.preStdRob = 1
self.postStdMethod = 0; self.postStdRob = 1
self.mergeType = 0
self.commitOnChange = 0
self.loadSettings()
# GUI
# info
box = QVGroupBox("Info", self.controlArea)
self.infoa = QLabel('No data on input.', box)
self.infob = QLabel('', box)
# preprocessing
OWGUI.separator(self.controlArea)
box = QVGroupBox("Preprocessing", self.controlArea)
labels = [x[0] for x in self.std]
OWGUI.comboBox(box, self, 'preStdMethod', label=None, labelWidth=None, orientation='vertical', items=labels, callback=self.selectionChange)
self.preRobBtn = OWGUI.checkBox(box, self, "preStdRob", "Robust standardization", callback=self.selectionChange)
# merge
OWGUI.separator(self.controlArea)
self.mergeTypes = [(0, "No merging"), ('mean', 'Mean'), ('median', 'Median'), ('min', 'Minimum expression'), ('max', 'Maximum expression')]
labels = [x[1] for x in self.mergeTypes]
OWGUI.radioButtonsInBox(self.controlArea, self, 'mergeType', labels, box='Merge Replicas', tooltips=None, callback=self.selectionChange)
# postprocessing
OWGUI.separator(self.controlArea)
self.boxPostproc = QVGroupBox("Postprocessing", self.controlArea)
labels = [x[0] for x in self.std]
OWGUI.comboBox(self.boxPostproc, self, 'postStdMethod', label=None, labelWidth=None, orientation='vertical', items=labels, callback=self.selectionChange)
self.postRobBtn = OWGUI.checkBox(self.boxPostproc, self, "postStdRob", "Robust standardization", callback=self.selectionChange)
# output
OWGUI.separator(self.controlArea)
box = QVGroupBox("Output", self.controlArea)
OWGUI.checkBox(box, self, 'commitOnChange', 'Commit data on selection change')
self.commitBtn = OWGUI.button(box, self, "Commit", callback=self.selectionChange, disabled=1)
self.setBtnsState()
self.resize(100,100)
def __init__(self, parent=None, signalManager = None, name='Approximate Profiles'):
self.callbackDeposit = [] # deposit for OWGUI callback functions
OWWidget.__init__(self, parent, signalManager, name)
self._data = None # exampleTable
self._dataN = None # 2d numeric array
self._chipdata = None # [(dirname0, [et0, et1, ...]), ...]
self._chipdataN = None # 3d numeric array
self.kernel = 0
self.kernels = ["Orthogonal polynomials", "Trigonometric functions"]
self.kernelSize = None
self.kernelSizes = [ ["Const"] + map(lambda x: "degree <= %i"%x, range(1,99)),
["Const", "cos x", "sin x"] + reduce(lambda x,y: x+[y[0],y[1]], map(lambda i: ("cos %ix"%i, "sin %ix"%i), range(2,99)), [])
]
self.useSignificance = 0
self.alpha = 3
self.alphas = [0.0001, 0.001, 0.01, 0.05, 0.1, 0.2, 0.5]
self.commitOnChange = 1
# Settings
self.loadSettings()
# GUI: info, comboKernelSize, cbUseSignificance, vboxSignificance, commitBtn
# info
box = QVGroupBox("Info", self.controlArea)
self.infoa = QLabel("No examples on input", box)
OWGUI.separator(box,250)
self.infob = QLabel("No structured data on input", box)
OWGUI.separator(self.controlArea)
# kernel selection
box = QVGroupBox("Kernel functions", self.controlArea)
OWGUI.comboBox(box, self, "kernel", items=self.kernels, callback=self.kernelChange)
OWGUI.separator(self.controlArea)
# kernel settings
box = QVGroupBox("Kernel settings", self.controlArea)
self.comboKernelSize = OWGUI.comboBox(box, self, "kernelSize", callback=self.kernelSizeChange, label="Number of kernel functions", labelWidth=135, orientation="horizontal", valueType=int)
self.comboKernelSize.setDisabled(1)
self.cbUseSignificance = OWGUI.checkBox(box, self, "useSignificance", "Significance of coefficients (F-statistics)", callback=self.useSignificanceChange, tooltip="Use kernels with coefficients significantly different from 0.")
self.vboxSignificance = QVBox(box)
OWGUI.comboBox(self.vboxSignificance, self, "alpha", items = self.alphas, callback=self.alphaChange, label="p <", labelWidth=20, orientation="horizontal")
OWGUI.separator(self.controlArea)
# output
box = QVGroupBox("Output", self.controlArea)
OWGUI.checkBox(box, self, 'commitOnChange', 'Commit data on selection change')
self.commitBtn = OWGUI.button(box, self, "Commit", callback=self.senddata, disabled=1)
self.inputs = [("Examples", ExampleTable, self.data), ("Structured Data", DataFiles, self.chipdata)]
self.outputs = [("Approximated Examples", ExampleTable, Default), ("Approximation Coefficients", ExampleTable), ("Approximated Structured Data", DataFiles, Default), ("Structured Approximation Coefficients", DataFiles)]
self.resize(200,100)
def __init__(self, parent=None, signalManager = None):
OWWidget.__init__(self, parent, signalManager, 'Example Selector')
self.callbackDeposit = []
self.inputs = [("Example Selection", ExampleSelection, self.loadselection, Multiple + Default), ("Structured Data", DataFiles, self.chipdata)]
self.outputs = [("Example Selection", ExampleSelection), ("Selected Structured Data", DataFiles, Default), ("Other Structured Data", DataFiles)]
# Settings
self.negate = 0
self.commitOnChange = 1
self.sendNotSelectedData = 1
self.loadSettings()
self.selectors = {}
self.data = None
# GUI
# info
box = QVGroupBox("Info", self.controlArea)
self.infoa = QLabel('No data on input.', box)
self.infob = QLabel('', box)
OWGUI.separator(self.controlArea)
box.setMinimumWidth(170)
# gene selection
self.layout=QVBoxLayout(self.mainArea)
box = QVGroupBox("Gene Selection", self.mainArea)
self.table=QTable(box)
self.table.setSelectionMode(QTable.NoSelection)
self.layout.add(box)
self.table.hide()
self.drawtable()
OWGUI.checkBox(box, self, 'negate', 'Negate', callback = self.selectionChange)
# output
box = QVGroupBox("Output", self.controlArea)
OWGUI.checkBox(box, self, 'sendNotSelectedData', 'Send not selected data', callback=self.selectionChange)
OWGUI.checkBox(box, self, 'commitOnChange', 'Commit data on change')
self.commitBtn = OWGUI.button(box, self, "Commit", callback=self.senddata, disabled=1)
self.resize(700,100)
def __init__(self, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager, 'Data Distance')
self.inputs = [("Structured Data", DataFiles, self.chipdata)]
self.outputs = [("Distance Matrix", orange.SymMatrix)]
self.Metrics = 0
self.loadSettings()
self.data = []
## self.metrics = [("Euclidean", orange.ExamplesDistanceConstructor_Euclidean),
## ("Manhattan", orange.ExamplesDistanceConstructor_Manhattan),
## ("Hamming", orange.ExamplesDistanceConstructor_Hamming)]
self.metrics = [("Manhattan", distManhattan),
("Euclidean", distEuclidean),
("1 - (Pearson correlation coefficient)", distPearson),
("1 - (Spearman rank correlation coefficient)",
distSpearman)]
# GUI
self.mainArea.setFixedWidth(0)
# Info box
box = QVGroupBox("Info", self.controlArea)
self.infoa = QLabel('No data on input.', box)
self.infob = QLabel('', box)
OWGUI.separator(self.controlArea)
# Distance metrics selection
items = [x[0] for x in self.metrics]
OWGUI.comboBox(
self.controlArea,
self,
"Metrics",
box="Distance Metrics",
items=items,
tooltip="Metrics to measure distance between data sets.",
callback=self.onMetricsChange)
self.resize(384, 138)
def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
OWWidget.__init__(self, parent, signalManager, name)
self.outputs = [("Expression Data", ExampleTable)]
## Settings
self.selectedAnnotation = 0
self.includeIf = False
self.minSamples = 3
self.autoCommit = False
self.outputRows = 0
self.mergeSpots = True
self.filterString = ""
self.currentGds = None
self.selectionChanged = False
self.autoCommit = False
self.gdsSelectionStates = {}
self.splitterSettings = [
'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xea\x00\x00\x00\xd7\x01\x00\x00\x00\x07\x01\x00\x00\x00\x02',
'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xb5\x00\x00\x02\x10\x01\x00\x00\x00\x07\x01\x00\x00\x00\x01'
]
self.datasetNames = {}
self.loadSettings()
self.datasetName = ""
## GUI
self.infoBox = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"Initializing\n\n"
)
box = OWGUI.widgetBox(self.controlArea, "Output", addSpace=True)
OWGUI.radioButtonsInBox(box, self, "outputRows",
["Genes or spots", "Samples"], "Rows",
callback=self.commitIf)
OWGUI.checkBox(box, self, "mergeSpots", "Merge spots of same gene",
callback=self.commitIf)
OWGUI.separator(box)
self.nameEdit = OWGUI.lineEdit(
box, self, "datasetName", "Data set name",
tooltip="Override the default output data set name",
callback=self.onNameEdited
)
self.nameEdit.setPlaceholderText("")
box = OWGUI.widgetBox(self.controlArea, "Commit", addSpace=True)
self.commitButton = OWGUI.button(box, self, "Commit",
callback=self.commit)
cb = OWGUI.checkBox(box, self, "autoCommit", "Commit on any change")
OWGUI.setStopper(self, self.commitButton, cb, "selectionChanged",
self.commit)
OWGUI.rubber(self.controlArea)
self.filterLineEdit = OWGUIEx.lineEditHint(
self.mainArea, self, "filterString", "Filter",
caseSensitive=False, matchAnywhere=True,
callback=self.filter, delimiters=" ")
splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(splitter)
self.treeWidget = QTreeView(splitter)
self.treeWidget.setSelectionMode(QAbstractItemView.SingleSelection)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSortingEnabled(True)
self.treeWidget.setAlternatingRowColors(True)
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)
linkdelegate = LinkStyledItemDelegate(self.treeWidget)
self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
self.treeWidget.setItemDelegateForColumn(
0, OWGUI.IndicatorItemDelegate(self.treeWidget,
role=Qt.DisplayRole))
proxyModel = MySortFilterProxyModel(self.treeWidget)
self.treeWidget.setModel(proxyModel)
self.treeWidget.selectionModel().selectionChanged.connect(
self.updateSelection
)
self.treeWidget.viewport().setMouseTracking(True)
splitterH = QSplitter(Qt.Horizontal, splitter)
box = OWGUI.widgetBox(splitterH, "Description")
self.infoGDS = OWGUI.widgetLabel(box, "")
self.infoGDS.setWordWrap(True)
OWGUI.rubber(box)
box = OWGUI.widgetBox(splitterH, "Sample Annotations")
self.annotationsTree = QTreeWidget(box)
self.annotationsTree.setHeaderLabels(
["Type (Sample annotations)", "Sample count"]
)
self.annotationsTree.setRootIsDecorated(True)
box.layout().addWidget(self.annotationsTree)
self.annotationsTree.itemChanged.connect(
self.annotationSelectionChanged
)
self._annotationsUpdating = False
self.splitters = splitter, splitterH
for sp, setting in zip(self.splitters, self.splitterSettings):
sp.splitterMoved.connect(self.splitterMoved)
sp.restoreState(setting)
self.searchKeys = ["dataset_id", "title", "platform_organism",
"description"]
self.gds = []
self.gds_info = None
self.resize(1000, 600)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._executor = ThreadExecutor()
func = partial(get_gds_model,
methodinvoke(self, "_setProgress", (float,)))
self._inittask = Task(function=func)
self._inittask.finished.connect(self._initializemodel)
self._executor.submit(self._inittask)
self._datatask = None
def __init__(self, parent=None, signalManager = None, name='GSEA'):
OWWidget.__init__(self, parent, signalManager, name)
self.inputs = [("Examples", ExampleTable, self.setData)]
self.outputs = [("Examples with selected genes only", ExampleTable), ("Results", ExampleTable), ("Distance Matrix", orange.SymMatrix) ]
self.res = None
self.dm = None
self.name = 'GSEA'
self.minSubsetSize = 3
self.minSubsetSizeC = True
self.maxSubsetSize = 1000
self.maxSubsetSizeC = True
self.minSubsetPart = 10
self.minSubsetPartC = True
self.perms = 100
self.csgm = False
self.gsgo = False
self.gskegg = False
self.buildDistances = False
self.selectedPhenVar = 0
self.organismIndex = 0
self.atLeast = 3
self.permutationTypes = [("Phenotype", "p"),("Gene", "g") ]
self.ptype = 0
self.correlationTypes = [ ("Signal2Noise", "s2n") ]
self.ctype = 0
self.data = None
self.geneSets = {}
self.tabs = OWGUI.tabWidget(self.controlArea)
ca = OWGUI.createTabPage(self.tabs, "Basic")
box = OWGUI.widgetBox(ca, 'Organism')
#FROM KEGG WIDGET - organism selection
self.organismTaxids = []
self.organismComboBox = cb = OWGUI.comboBox(box, self, "organismIndex", items=[], debuggingEnabled=0) #changed
cb.setMaximumWidth(200)
#OWGUI.checkBox(box, self, "csgm", "Case sensitive gene matching")
box2 = OWGUI.widgetBox(ca, "Descriptors")
self.phenCombo = OWGUI.comboBox(box2, self, "selectedPhenVar", items=[], callback=self.phenComboChange, label="Phenotype:")
self.geneCombo = OWGUI.comboBox(box2, self, "selectedGeneVar", items=[], label = "Gene:")
self.allowComboChangeCallback = False
ma = self.mainArea
self.listView = QTreeWidget(ma)
ma.layout().addWidget(self.listView)
self.listView.setAllColumnsShowFocus(1)
self.listView.setColumnCount(9)
self.listView.setHeaderLabels(["Collection", "Geneset", "NES", "ES", "P-value", "FDR", "Size", "Matched Size", "Genes"])
self.listView.header().setStretchLastSection(True)
self.listView.header().setClickable(True)
self.listView.header().setSortIndicatorShown(True)
self.listView.setSortingEnabled(True)
#self.listView.header().setResizeMode(0, QHeaderView.Stretch)
self.listView.setSelectionMode(QAbstractItemView.NoSelection)
self.connect(self.listView, SIGNAL("itemSelectionChanged()"), self.newPathwaySelected)
OWGUI.separator(ca)
OWGUI.widgetLabel(ca, "Phenotype selection:")
self.psel = PhenotypesSelection(ca)
self.resize(600,50)
OWGUI.separator(ca)
OWGUI.checkBox(ca, self, "buildDistances", "Compute geneset distances")
self.btnApply = OWGUI.button(ca, self, "&Compute", callback = self.compute, disabled=0)
fileBox = OWGUI.widgetBox(ca, orientation='horizontal')
OWGUI.button(fileBox, self, "Load", callback = self.loadData, disabled=0, debuggingEnabled=0)
OWGUI.button(fileBox, self, "Save", callback = self.saveData, disabled=0, debuggingEnabled=0)
#ca.layout().addStretch(1)
ca = OWGUI.createTabPage(self.tabs, "Gene sets")
box = OWGUI.widgetBox(ca)
self.gridSel = []
self.geneSel = [] #FIXME temporary disabled - use the same as in new "David" widget
self.lbgs = OWGUI.listBox(box, self, "gridSel", "geneSel", selectionMode = QListWidget.MultiSelection)
OWGUI.button(box, self, "From &File", callback = self.addCollection, disabled=0, debuggingEnabled=0)
box = OWGUI.widgetBox(box, "Additional sources:")
OWGUI.checkBox(box, self, "gskegg", "KEGG pathways")
OWGUI.checkBox(box, self, "gsgo", "GO terms")
#ca.layout().addStretch(1)
ca = OWGUI.createTabPage(self.tabs, "Settings")
box = OWGUI.widgetBox(ca, 'Properties')
self.permTypeF = OWGUI.comboBoxWithCaption(box, self, "ptype", items=nth(self.permutationTypes, 0), \
tooltip="Permutation type.", label="Permute")
_ = OWGUI.spin(box, self, "perms", 50, 1000, orientation="horizontal", label="Times")
self.corTypeF = OWGUI.comboBoxWithCaption(box, self, "ctype", items=nth(self.correlationTypes, 0), \
tooltip="Correlation type.", label="Correlation")
box = OWGUI.widgetBox(ca, 'Subset Filtering')
_,_ = OWGUI.checkWithSpin(box, self, "Min. Subset Size", 1, 10000, "minSubsetSizeC", "minSubsetSize", "") #TODO check sizes
_,_ = OWGUI.checkWithSpin(box, self, "Max. Subset Size", 1, 10000, "maxSubsetSizeC", "maxSubsetSize", "")
_,_ = OWGUI.checkWithSpin(box, self, "Min. Subset Part (%)", 1, 100, "minSubsetPartC", "minSubsetPart", "")
box = OWGUI.widgetBox(ca, 'Gene Filtering')
_ = OWGUI.spin(box, self, "atLeast", 2, 10, label="Min. Values in Group")
ca.layout().addStretch(1)
self.addComment("Computation was not started.")
if sys.platform == "darwin":
self.loadFileName = os.path.expanduser("~/")
else:
self.loadFileName = "."
self.gridSels = []
self.loadSettings()
self.setBlocking(True)
QTimer.singleShot(0, self.UpdateOrganismComboBox)
def cleanInvalid(maxn):
"""
Removes invalid gene set selection
"""
notAllOk = True
while notAllOk:
self.gridSels = getattr(self, "gridSels")
notAllOk = False
for i,a in enumerate(self.gridSels):
if a >= maxn:
self.gridSels.pop(i)
notAllOk = True
break
cleanInvalid(len(self.geneSel))
self.gridSel = self.gridSels
self.gridSels = self.gridSel
def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
OWWidget.__init__(self, parent, signalManager, name)
self.selectionChanged = False
self.filterString = ""
self.datasetName = ""
## GUI
box = gui.widgetBox(self.controlArea, "Info", addSpace=True)
self.infoBox = gui.widgetLabel(box, "Initializing\n\n")
box = gui.widgetBox(self.controlArea, "Output", addSpace=True)
gui.radioButtonsInBox(box, self, "outputRows",
["Genes in rows", "Samples in rows"], "Rows",
callback=self.commitIf)
gui.checkBox(box, self, "mergeSpots", "Merge spots of same gene",
callback=self.commitIf)
gui.separator(box)
self.nameEdit = gui.lineEdit(
box, self, "datasetName", "Data set name",
tooltip="Override the default output data set name",
callback=self.onNameEdited
)
self.nameEdit.setPlaceholderText("")
if sys.version_info < (3, ):
box = gui.widgetBox(self.controlArea, "Commit", addSpace=True)
self.commitButton = gui.button(
box, self, "Commit", callback=self.commit)
cb = gui.checkBox(box, self, "autoCommit", "Commit on any change")
gui.setStopper(self, self.commitButton, cb, "selectionChanged",
self.commit)
else:
gui.auto_commit(self.controlArea, self, "autoCommit", "Commit",
box="Commit")
self.commitIf = self.commit
gui.rubber(self.controlArea)
gui.widgetLabel(self.mainArea, "Filter")
self.filterLineEdit = QLineEdit(
textChanged=self.filter
)
self.completer = TokenListCompleter(
self, caseSensitivity=Qt.CaseInsensitive
)
self.filterLineEdit.setCompleter(self.completer)
self.mainArea.layout().addWidget(self.filterLineEdit)
splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(splitter)
self.treeWidget = QTreeView(splitter)
self.treeWidget.setSelectionMode(QTreeView.SingleSelection)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSortingEnabled(True)
self.treeWidget.setAlternatingRowColors(True)
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)
linkdelegate = LinkStyledItemDelegate(self.treeWidget)
self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
self.treeWidget.setItemDelegateForColumn(
0, gui.IndicatorItemDelegate(self.treeWidget,
role=Qt.DisplayRole))
proxyModel = MySortFilterProxyModel(self.treeWidget)
self.treeWidget.setModel(proxyModel)
self.treeWidget.selectionModel().selectionChanged.connect(
self.updateSelection
)
self.treeWidget.viewport().setMouseTracking(True)
splitterH = QSplitter(Qt.Horizontal, splitter)
box = gui.widgetBox(splitterH, "Description")
self.infoGDS = gui.widgetLabel(box, "")
self.infoGDS.setWordWrap(True)
gui.rubber(box)
box = gui.widgetBox(splitterH, "Sample Annotations")
self.annotationsTree = QTreeWidget(box)
self.annotationsTree.setHeaderLabels(
["Type (Sample annotations)", "Sample count"]
)
self.annotationsTree.setRootIsDecorated(True)
box.layout().addWidget(self.annotationsTree)
self.annotationsTree.itemChanged.connect(
self.annotationSelectionChanged
)
self._annotationsUpdating = False
self.splitters = splitter, splitterH
for sp, setting in zip(self.splitters, self.splitterSettings):
sp.splitterMoved.connect(self.splitterMoved)
sp.restoreState(setting)
self.searchKeys = ["dataset_id", "title", "platform_organism",
"description"]
self.gds = []
self.gds_info = None
self.resize(1000, 600)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._executor = ThreadExecutor()
func = partial(get_gds_model,
methodinvoke(self, "_setProgress", (float,)))
self._inittask = Task(function=func)
self._inittask.finished.connect(self._initializemodel)
self._executor.submit(self._inittask)
self._datatask = None
def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
OWWidget.__init__(self, parent, signalManager, name)
self.outputs = [("Expression Data", ExampleTable)]
## Settings
self.selectedAnnotation = 0
self.includeIf = False
self.minSamples = 3
self.autoCommit = False
self.outputRows = 1
self.mergeSpots = True
self.filterString = ""
self.currentGds = None
self.selectionChanged = False
self.autoCommit = False
self.gdsSelectionStates = {}
self.splitterSettings = [
'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xea\x00\x00\x00\xd7\x01\x00\x00\x00\x07\x01\x00\x00\x00\x02',
'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xb5\x00\x00\x02\x10\x01\x00\x00\x00\x07\x01\x00\x00\x00\x01'
]
self.datasetNames = {}
self.loadSettings()
self.datasetName = ""
## GUI
self.infoBox = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"Initializing\n\n"
)
box = OWGUI.widgetBox(self.controlArea, "Output", addSpace=True)
OWGUI.radioButtonsInBox(box, self, "outputRows",
["Genes in rows", "Samples in rows"], "Rows",
callback=self.commitIf)
OWGUI.checkBox(box, self, "mergeSpots", "Merge spots of same gene",
callback=self.commitIf)
OWGUI.separator(box)
self.nameEdit = OWGUI.lineEdit(
box, self, "datasetName", "Data set name",
tooltip="Override the default output data set name",
callback=self.onNameEdited
)
self.nameEdit.setPlaceholderText("")
box = OWGUI.widgetBox(self.controlArea, "Commit", addSpace=True)
self.commitButton = OWGUI.button(box, self, "Commit",
callback=self.commit)
cb = OWGUI.checkBox(box, self, "autoCommit", "Commit on any change")
OWGUI.setStopper(self, self.commitButton, cb, "selectionChanged",
self.commit)
OWGUI.rubber(self.controlArea)
self.filterLineEdit = OWGUIEx.lineEditHint(
self.mainArea, self, "filterString", "Filter",
caseSensitive=False, matchAnywhere=True,
callback=self.filter, delimiters=" ")
splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(splitter)
self.treeWidget = QTreeView(splitter)
self.treeWidget.setSelectionMode(QAbstractItemView.SingleSelection)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSortingEnabled(True)
self.treeWidget.setAlternatingRowColors(True)
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)
linkdelegate = LinkStyledItemDelegate(self.treeWidget)
self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
self.treeWidget.setItemDelegateForColumn(
0, OWGUI.IndicatorItemDelegate(self.treeWidget,
role=Qt.DisplayRole))
proxyModel = MySortFilterProxyModel(self.treeWidget)
self.treeWidget.setModel(proxyModel)
self.treeWidget.selectionModel().selectionChanged.connect(
self.updateSelection
)
self.treeWidget.viewport().setMouseTracking(True)
splitterH = QSplitter(Qt.Horizontal, splitter)
box = OWGUI.widgetBox(splitterH, "Description")
self.infoGDS = OWGUI.widgetLabel(box, "")
self.infoGDS.setWordWrap(True)
OWGUI.rubber(box)
box = OWGUI.widgetBox(splitterH, "Sample Annotations")
self.annotationsTree = QTreeWidget(box)
self.annotationsTree.setHeaderLabels(
["Type (Sample annotations)", "Sample count"]
)
self.annotationsTree.setRootIsDecorated(True)
box.layout().addWidget(self.annotationsTree)
self.annotationsTree.itemChanged.connect(
self.annotationSelectionChanged
)
self._annotationsUpdating = False
self.splitters = splitter, splitterH
for sp, setting in zip(self.splitters, self.splitterSettings):
sp.splitterMoved.connect(self.splitterMoved)
sp.restoreState(setting)
self.searchKeys = ["dataset_id", "title", "platform_organism",
"description"]
self.gds = []
self.gds_info = None
self.resize(1000, 600)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._executor = ThreadExecutor()
func = partial(get_gds_model,
methodinvoke(self, "_setProgress", (float,)))
self._inittask = Task(function=func)
self._inittask.finished.connect(self._initializemodel)
self._executor.submit(self._inittask)
self._datatask = None
def __init__(self, parent=None, signalManager=None, name="Normalize Expression Array"):
OWWidget.__init__(self, parent, signalManager, name, wantGraph=True)
self.inputs = [("Expression array", ExampleTable, self.setData)]
self.outputs = [("Normalized expression array", ExampleTable, Default), ("Filtered expression array", ExampleTable)]
self.selectedGroup = 0
self.selectedCenterMethod = 0
self.selectedMergeMethod = 0
self.zCutoff = 1.96
self.appendZScore = False
self.appendRIValues = False
self.autoCommit = False
self.loadSettings()
## GUI
self.infoBox = OWGUI.widgetLabel(OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"No data on input.")
box = OWGUI.widgetBox(self.controlArea, "Split by", addSpace=True)
self.groupCombo = OWGUI.comboBox(box, self, "selectedGroup",
callback=self.onGroupSelection
)
self.centerCombo = OWGUI.comboBox(self.controlArea, self, "selectedCenterMethod",
box="Center Fold-change Using",
items=[name for name, _ in self.CENTER_METHODS],
callback=self.onCenterMethodChange,
addSpace=True
)
self.mergeCombo = OWGUI.comboBox(self.controlArea, self, "selectedMergeMethod",
box="Merge Replicates",
items=[name for name, _ in self.MERGE_METHODS],
tooltip="Select the method for replicate merging",
callback=self.onMergeMethodChange,
addSpace=True
)
box = OWGUI.doubleSpin(self.controlArea, self, "zCutoff", 0.0, 3.0, 0.01,
box="Z-Score Cutoff",
callback=[self.replotMA, self.commitIf])
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Ouput")
OWGUI.checkBox(box, self, "appendZScore", "Append Z-Scores",
tooltip="Append calculated Z-Scores to output",
callback=self.commitIf
)
OWGUI.checkBox(box, self, "appendRIValues", "Append Log Ratio and Intensity values",
tooltip="Append calculated Log Ratio and Intensity values to output data",
callback=self.commitIf
)
cb = OWGUI.checkBox(box, self, "autoCommit", "Commit on change",
tooltip="Commit data on any change",
callback=self.commitIf
)
b = OWGUI.button(box, self, "Commit", callback=self.commit)
OWGUI.setStopper(self, b, cb, "changedFlag", callback=self.commit)
self.connect(self.graphButton, SIGNAL("clicked()"), self.saveGraph)
OWGUI.rubber(self.controlArea)
self.graph = OWGraph(self.mainArea)
self.graph.setAxisTitle(QwtPlot.xBottom, "Intensity: log<sub>10</sub>(R*G)")
self.graph.setAxisTitle(QwtPlot.yLeft, "Log ratio: log<sub>2</sub>(R/G)")
self.graph.showFilledSymbols = True
self.mainArea.layout().addWidget(self.graph)
self.groups = []
self.split_data = None, None
self.merged_splits = None, None
self.centered = None, None
self.changedFlag = False
self.data = None
self.resize(800, 600)
def __init__(self,parent=None, signalManager = None):
OWWidget.__init__(self, parent, signalManager, "Nomogram", 1)
#self.setWFlags(Qt.WResizeNoErase | Qt.WRepaintNoErase) #this works like magic.. no flicker during repaint!
self.parent = parent
# self.setWFlags(self.getWFlags()+Qt.WStyle_Maximize)
self.callbackDeposit = [] # deposit for OWGUI callback functions
self.alignType = 0
self.contType = 0
self.yAxis = 0
self.probability = 0
self.verticalSpacing = 60
self.verticalSpacingContinuous = 100
self.diff_between_ordinal = 30
self.fontSize = 9
self.lineWidth = 1
self.histogram = 0
self.histogram_size = 10
self.data = None
self.cl = None
self.confidence_check = 0
self.confidence_percent = 95
self.sort_type = 0
self.loadSettings()
self.pointsName = ["Total", "Total"]
self.totalPointsName = ["Probability", "Probability"]
self.bnomogram = None
self.inputs=[("Classifier", orange.Classifier, self.classifier), ("Data", Orange.data.Table, self.data)]
self.TargetClassIndex = 0
self.targetCombo = OWGUI.comboBox(self.controlArea, self, "TargetClassIndex", " Target Class ", addSpace=True, tooltip='Select target (prediction) class in the model.', callback = self.setTarget)
self.alignRadio = OWGUI.radioButtonsInBox(self.controlArea, self, 'alignType', ['Align left', 'Align by zero influence'], box='Attribute placement',
tooltips=['Attributes in nomogram are left aligned', 'Attributes are not aligned, top scale represents true (normalized) regression coefficient value'],
addSpace=True,
callback=self.showNomogram)
self.verticalSpacingLabel = OWGUI.spin(self.alignRadio, self, 'verticalSpacing', 15, 200, label = 'Vertical spacing:', orientation = 0, tooltip='Define space (pixels) between adjacent attributes.', callback = self.showNomogram)
self.ContRadio = OWGUI.radioButtonsInBox(self.controlArea, self, 'contType', ['1D projection', '2D curve'], 'Continuous attributes',
tooltips=['Continuous attribute are presented on a single scale', 'Two dimensional space is used to present continuous attributes in nomogram.'],
addSpace=True,
callback=[lambda:self.verticalSpacingContLabel.setDisabled(not self.contType), self.showNomogram])
self.verticalSpacingContLabel = OWGUI.spin(OWGUI.indentedBox(self.ContRadio, sep=OWGUI.checkButtonOffsetHint(self.ContRadio.buttons[-1])), self, 'verticalSpacingContinuous', 15, 200, label = "Height", orientation=0, tooltip='Define space (pixels) between adjacent 2d presentation of attributes.', callback = self.showNomogram)
self.verticalSpacingContLabel.setDisabled(not self.contType)
self.yAxisRadio = OWGUI.radioButtonsInBox(self.controlArea, self, 'yAxis', ['Point scale', 'Log odds ratios'], 'Scale',
tooltips=['values are normalized on a 0-100 point scale','values on top axis show log-linear contribution of attribute to full model'],
addSpace=True,
callback=self.showNomogram)
layoutBox = OWGUI.widgetBox(self.controlArea, "Display", orientation=1, addSpace=True)
self.probabilityCheck = OWGUI.checkBox(layoutBox, self, 'probability', 'Show prediction', tooltip='', callback = self.setProbability)
self.CICheck, self.CILabel = OWGUI.checkWithSpin(layoutBox, self, 'Confidence intervals (%):', min=1, max=99, step = 1, checked='confidence_check', value='confidence_percent', checkCallback=self.showNomogram, spinCallback = self.showNomogram)
self.histogramCheck, self.histogramLabel = OWGUI.checkWithSpin(layoutBox, self, 'Show histogram, size', min=1, max=30, checked='histogram', value='histogram_size', step = 1, tooltip='-(TODO)-', checkCallback=self.showNomogram, spinCallback = self.showNomogram)
OWGUI.separator(layoutBox)
self.sortOptions = ["No sorting", "Absolute importance", "Positive influence", "Negative influence"]
self.sortBox = OWGUI.comboBox(layoutBox, self, "sort_type", label="Sort by ", items=self.sortOptions, callback = self.sortNomogram, orientation="horizontal")
OWGUI.rubber(self.controlArea)
self.connect(self.graphButton, SIGNAL("clicked()"), self.menuItemPrinter)
#add a graph widget
self.header = OWNomogramHeader(None, self.mainArea)
self.header.setFixedHeight(60)
self.header.setVerticalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.header.setHorizontalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.graph = OWNomogramGraph(self.bnomogram, self.mainArea)
self.graph.setMinimumWidth(200)
self.graph.setHorizontalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.footer = OWNomogramHeader(None, self.mainArea)
self.footer.setFixedHeight(60*2+10)
self.footer.setVerticalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.footer.setHorizontalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.mainArea.layout().addWidget(self.header)
self.mainArea.layout().addWidget(self.graph)
self.mainArea.layout().addWidget(self.footer)
self.resize(700,500)
#self.repaint()
#self.update()
# mouse pressed flag
self.mousepr = False
def __init__(self,
parent=None,
signalManager=None,
name="Normalize Expression Array"):
OWWidget.__init__(self, parent, signalManager, name, wantGraph=True)
self.inputs = [("Expression array", ExampleTable, self.setData)]
self.outputs = [("Normalized expression array", ExampleTable, Default),
("Filtered expression array", ExampleTable)]
self.selectedGroup = 0
self.selectedCenterMethod = 0
self.selectedMergeMethod = 0
self.zCutoff = 1.96
self.appendZScore = False
self.appendRIValues = False
self.autoCommit = False
self.loadSettings()
## GUI
self.infoBox = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"No data on input.")
box = OWGUI.widgetBox(self.controlArea, "Split by", addSpace=True)
self.groupCombo = OWGUI.comboBox(box,
self,
"selectedGroup",
callback=self.onGroupSelection)
self.centerCombo = OWGUI.comboBox(
self.controlArea,
self,
"selectedCenterMethod",
box="Center Fold-change Using",
items=[name for name, _ in self.CENTER_METHODS],
callback=self.onCenterMethodChange,
addSpace=True)
self.mergeCombo = OWGUI.comboBox(
self.controlArea,
self,
"selectedMergeMethod",
box="Merge Replicates",
items=[name for name, _ in self.MERGE_METHODS],
tooltip="Select the method for replicate merging",
callback=self.onMergeMethodChange,
addSpace=True)
box = OWGUI.doubleSpin(self.controlArea,
self,
"zCutoff",
0.0,
3.0,
0.01,
box="Z-Score Cutoff",
callback=[self.replotMA, self.commitIf])
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Ouput")
OWGUI.checkBox(box,
self,
"appendZScore",
"Append Z-Scores",
tooltip="Append calculated Z-Scores to output",
callback=self.commitIf)
OWGUI.checkBox(
box,
self,
"appendRIValues",
"Append Log Ratio and Intensity values",
tooltip=
"Append calculated Log Ratio and Intensity values to output data",
callback=self.commitIf)
cb = OWGUI.checkBox(box,
self,
"autoCommit",
"Commit on change",
tooltip="Commit data on any change",
callback=self.commitIf)
b = OWGUI.button(box, self, "Commit", callback=self.commit)
OWGUI.setStopper(self, b, cb, "changedFlag", callback=self.commit)
self.connect(self.graphButton, SIGNAL("clicked()"), self.saveGraph)
OWGUI.rubber(self.controlArea)
self.graph = OWGraph(self.mainArea)
self.graph.setAxisTitle(QwtPlot.xBottom,
"Intensity: log<sub>10</sub>(R*G)")
self.graph.setAxisTitle(QwtPlot.yLeft,
"Log ratio: log<sub>2</sub>(R/G)")
self.graph.showFilledSymbols = True
self.mainArea.layout().addWidget(self.graph)
self.groups = []
self.split_data = None, None
self.merged_splits = None, None
self.centered = None, None
self.changedFlag = False
self.data = None
self.resize(800, 600)
def __init__(self, parent=None, signalManager=None, name="KEGG Pathways"):
OWWidget.__init__(self, parent, signalManager, name, wantGraph=True)
self.inputs = [("Examples", Orange.data.Table, self.SetData),
("Reference", Orange.data.Table, self.SetRefData)]
self.outputs = [("Selected Examples", Orange.data.Table),
("Unselected Examples", Orange.data.Table)]
self.organismIndex = 0
self.geneAttrIndex = 0
self.autoCommit = False
self.autoResize = True
self.useReference = False
self.useAttrNames = 0
self.showOrthology = True
self.loadSettings()
self.organismCodes = []
self._changedFlag = False
self.controlArea.setMaximumWidth(250)
box = OWGUI.widgetBox(self.controlArea, "Info")
self.infoLabel = OWGUI.widgetLabel(box, "No data on input\n")
# Organism selection.
box = OWGUI.widgetBox(self.controlArea, "Organism")
self.organismComboBox = OWGUI.comboBox(
box, self, "organismIndex",
items=[],
callback=self.Update,
addSpace=True,
debuggingEnabled=0,
tooltip="Select the organism of the input genes")
# Selection of genes attribute
box = OWGUI.widgetBox(self.controlArea, "Gene attribute")
self.geneAttrCandidates = VariableListModel(parent=self)
self.geneAttrCombo = OWGUI.comboBox(
box, self, "geneAttrIndex", callback=self.Update)
self.geneAttrCombo.setModel(self.geneAttrCandidates)
OWGUI.checkBox(box, self, "useAttrNames",
"Use variable names",
disables=[(-1, self.geneAttrCombo)],
callback=self.Update)
self.geneAttrCombo.setDisabled(bool(self.useAttrNames))
OWGUI.separator(self.controlArea)
OWGUI.checkBox(self.controlArea, self, "useReference",
"From signal",
box="Reference",
callback=self.Update)
OWGUI.separator(self.controlArea)
OWGUI.checkBox(self.controlArea, self, "showOrthology",
"Show pathways in full orthology",
box="Orthology",
callback=self.UpdateListView)
OWGUI.checkBox(self.controlArea, self, "autoResize",
"Resize to fit",
box="Image",
callback=self.UpdatePathwayViewTransform)
box = OWGUI.widgetBox(self.controlArea, "Cache Control")
OWGUI.button(box, self, "Clear cache",
callback=self.ClearCache,
tooltip="Clear all locally cached KEGG data.")
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Selection")
cb = OWGUI.checkBox(box, self, "autoCommit", "Commit on update")
button = OWGUI.button(box, self, "Commit", callback=self.Commit,
default=True)
OWGUI.setStopper(self, button, cb, "_changedFlag", self.Commit)
OWGUI.rubber(self.controlArea)
spliter = QSplitter(Qt.Vertical, self.mainArea)
self.pathwayView = PathwayView(self, spliter)
self.pathwayView.scene().selectionChanged.connect(
self._onSelectionChanged
)
self.mainArea.layout().addWidget(spliter)
self.listView = QTreeWidget(spliter)
spliter.addWidget(self.listView)
self.listView.setAllColumnsShowFocus(1)
self.listView.setColumnCount(4)
self.listView.setHeaderLabels(["Pathway", "P value",
"Genes", "Reference"])
self.listView.setSelectionMode(QTreeWidget.SingleSelection)
self.listView.setSortingEnabled(True)
self.listView.setMaximumHeight(200)
self.connect(self.listView,
SIGNAL("itemSelectionChanged()"),
self.UpdatePathwayView)
self.connect(self.graphButton,
SIGNAL("clicked()"),
self.saveGraph)
select = QAction(
"Select All", self,
shortcut=QKeySequence.SelectAll
)
select.triggered.connect(self.selectAll)
self.addAction(select)
self.data = None
self.refData = None
self.resize(800, 600)
self.connect(self,
SIGNAL("widgetStateChanged(QString, int, QString)"),
self.onStateChange)
self.has_new_data = False
self.has_new_reference_set = False
self._executor = ThreadExecutor()
self.setEnabled(False)
self.setBlocking(True)
QTimer.singleShot(0, self._initialize)
self.infoLabel.setText("Fetching organism definitions\n")
def __init__(self, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager, "MeshBrowser")
self.inputs = [("Reference data", ExampleTable, self.getReferenceData),
("Cluster data", ExampleTable, self.getClusterData)]
self.outputs = [("Selected examples", ExampleTable)]
# widget variables
self.loadedRef = 0
self.loadedClu = 0
self.maxPValue = 0.05
self.minExamplesInTerm = 5
self.multi = 1
self.reference = None
self.cluster = None
self.loadSettings()
self.mesh = obiMeSH() # main object is created
self.dataLoaded = self.mesh.dataLoaded
# left pane
box = OWGUI.widgetBox(self.controlArea, "Info")
#box = QGroupBox("Info", self.controlArea)
self.infoa = OWGUI.label(box, self, "No reference data.")
self.infob = OWGUI.label(box, self, "No cluster data.")
self.ratio = OWGUI.label(box, self, "")
self.ref_att = OWGUI.label(box, self, "")
self.clu_att = OWGUI.label(box, self, "")
self.resize(960, 600)
OWGUI.separator(self.controlArea)
self.optionsBox = OWGUI.widgetBox(self.controlArea, "Options")
self.maxp = OWGUI.lineEdit(self.optionsBox,
self,
"maxPValue",
label="threshold:",
orientation="horizontal",
labelWidth=120,
valueType=float)
self.minf = OWGUI.lineEdit(self.optionsBox,
self,
"minExamplesInTerm",
label="min. frequency:",
orientation="horizontal",
labelWidth=120,
valueType=int)
#OWGUI.checkBox(self.optionsBox, self, 'multi', 'Multiple selection', callback= self.checkClicked)
OWGUI.button(self.optionsBox, self, "Refresh", callback=self.refresh)
# right pane
self.col_size = [280, 84, 84, 100, 110]
self.sort_col = 0
self.sort_dir = True
self.columns = [
'MeSH term', '# reference', '# cluster', 'p value',
'fold enrichment'
] # both datasets
self.splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(self.splitter)
# list view
self.meshLV = QTreeWidget(self.splitter)
#self.meshLV.setSelectionMode(QAbstractItemView.MultiSelection)
self.meshLV.setAllColumnsShowFocus(1)
self.meshLV.setColumnCount(len(self.columns))
self.meshLV.setHeaderLabels(self.columns)
self.meshLV.header().setClickable(True)
#self.meshLV.header().setSortIndicatorShown(True)
#self.meshLV.setSortingEnabled(True)
self.meshLV.setRootIsDecorated(True)
self.connect(self.meshLV, SIGNAL("itemSelectionChanged()"),
self.viewSelectionChanged)
#self.meshLV.setItemDelegateForColumn(3, EnrichmentColumnItemDelegate(self))
#self.tooltips = ListViewToolTip(self.meshLV,0, self.mesh.toDesc)
# table of significant mesh terms
self.sigTermsTable = QTableWidget(self.splitter)
self.sigTermsTable.setColumnCount(len(self.columns))
self.sigTermsTable.setRowCount(4)
## hide the vertical header
self.sigTermsTable.verticalHeader().hide()
#self.sigTermsTable.setLeftMargin(0)
#self.sigTermsTable.setSelectionMode(QAbstractItemView.MultiSelection)
for i in range(0, len(self.columns)):
self.sigTermsTable.horizontalHeader().resizeSection(
i, self.col_size[i])
self.meshLV.header().resizeSection(i, self.col_size[i])
self.sigTermsTable.setHorizontalHeaderLabels(self.columns)
self.connect(self.sigTermsTable, SIGNAL("itemSelectionChanged()"),
self.tableSelectionChanged)
self.connect(self.sigTermsTable,
SIGNAL("clicked(int,int,int,const QPoint&)"),
self.tableClicked)
self.splitter.show()
self.optionsBox.setDisabled(1)
def __init__(self, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager, "MeshBrowser")
self.inputs = [("Reference data", ExampleTable, self.getReferenceData), ("Cluster data", ExampleTable, self.getClusterData)]
self.outputs = [("Selected examples", ExampleTable)]
# widget variables
self.loadedRef = 0
self.loadedClu = 0
self.maxPValue = 0.05
self.minExamplesInTerm = 5
self.multi = 1
self.reference = None
self.cluster = None
self.loadSettings()
self.mesh = obiMeSH() # main object is created
self.dataLoaded = self.mesh.dataLoaded
# left pane
box = OWGUI.widgetBox(self.controlArea, "Info")
#box = QGroupBox("Info", self.controlArea)
self.infoa = OWGUI.label(box, self, "No reference data.")
self.infob = OWGUI.label(box, self, "No cluster data.")
self.ratio = OWGUI.label(box, self, "")
self.ref_att = OWGUI.label(box, self, "")
self.clu_att = OWGUI.label(box, self, "")
self.resize(960, 600)
OWGUI.separator(self.controlArea)
self.optionsBox = OWGUI.widgetBox(self.controlArea, "Options")
self.maxp = OWGUI.lineEdit(self.optionsBox, self, "maxPValue", label="threshold:", orientation="horizontal", labelWidth=120, valueType=float)
self.minf = OWGUI.lineEdit(self.optionsBox, self, "minExamplesInTerm", label="min. frequency:", orientation="horizontal", labelWidth=120, valueType=int)
#OWGUI.checkBox(self.optionsBox, self, 'multi', 'Multiple selection', callback= self.checkClicked)
OWGUI.button(self.optionsBox, self, "Refresh", callback=self.refresh)
# right pane
self.col_size = [280, 84, 84, 100, 110]
self.sort_col = 0
self.sort_dir = True
self.columns = ['MeSH term', '# reference', '# cluster', 'p value', 'fold enrichment'] # both datasets
self.splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(self.splitter)
# list view
self.meshLV = QTreeWidget(self.splitter)
#self.meshLV.setSelectionMode(QAbstractItemView.MultiSelection)
self.meshLV.setAllColumnsShowFocus(1)
self.meshLV.setColumnCount(len(self.columns))
self.meshLV.setHeaderLabels(self.columns)
self.meshLV.header().setClickable(True)
#self.meshLV.header().setSortIndicatorShown(True)
#self.meshLV.setSortingEnabled(True)
self.meshLV.setRootIsDecorated(True)
self.connect(self.meshLV, SIGNAL("itemSelectionChanged()"), self.viewSelectionChanged)
#self.meshLV.setItemDelegateForColumn(3, EnrichmentColumnItemDelegate(self))
#self.tooltips = ListViewToolTip(self.meshLV,0, self.mesh.toDesc)
# table of significant mesh terms
self.sigTermsTable = QTableWidget(self.splitter)
self.sigTermsTable.setColumnCount(len(self.columns))
self.sigTermsTable.setRowCount(4)
## hide the vertical header
self.sigTermsTable.verticalHeader().hide()
#self.sigTermsTable.setLeftMargin(0)
#self.sigTermsTable.setSelectionMode(QAbstractItemView.MultiSelection)
for i in range(0, len(self.columns)):
self.sigTermsTable.horizontalHeader().resizeSection(i, self.col_size[i])
self.meshLV.header().resizeSection(i, self.col_size[i])
self.sigTermsTable.setHorizontalHeaderLabels(self.columns)
self.connect(self.sigTermsTable, SIGNAL("itemSelectionChanged()"), self.tableSelectionChanged)
self.connect(self.sigTermsTable, SIGNAL("clicked(int,int,int,const QPoint&)"), self.tableClicked)
self.splitter.show()
self.optionsBox.setDisabled(1)
def __init__(self,
parent=None,
signalManager=None,
title="Molecule visualizer"):
super(OWMoleculeVisualizer, self).__init__(parent, signalManager,
title)
self.colorFragments = 1
self.showFragments = 0
self.selectedFragment = ""
self.moleculeSmiles = []
self.fragmentSmiles = []
self.defFragmentSmiles = []
self.smiles_var = 0
self.moleculeTitleAttr = 0
self.moleculeTitleAttributeList = []
self.selectedMoleculeTitleAttrs = []
self.fragmentSmilesAttr = 0
self.imageSize = 200
self.numColumns = 4
self.commitOnChange = 0
## GUI
box = OWGUI.widgetBox(self.controlArea, "Info", addSpace=True)
self.infoLabel = OWGUI.label(box, self, "Chemicals:")
box = OWGUI.radioButtonsInBox(self.controlArea,
self,
"showFragments",
["Show molecules", "Show fragments"],
"Show",
callback=self.updateitems)
self.showFragmentsRadioButton = box.buttons[-1]
self.markFragmentsCheckBox = OWGUI.checkBox(box,
self,
"colorFragments",
"Mark fragments",
callback=self._update)
box.setSizePolicy(QSizePolicy(QSizePolicy.Minimum,
QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
self.moleculeSmilesCombo = OWGUI.comboBox(self.controlArea,
self,
"smiles_var",
"Molecule SMILES Attribute",
callback=self.updateitems)
self.moleculeSmilesCombo.box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum))
self.smiles_var_model = VariableListModel(parent=self)
self.moleculeSmilesCombo.setModel(self.smiles_var_model)
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea,
"Molecule Title Attributes",
addSpace=True)
self.title_var_view = QListView(
selectionMode=QListView.ExtendedSelection)
self.title_var_model = VariableListModel(parent=self)
self.title_var_view.setModel(self.title_var_model)
self.title_var_view.selectionModel().selectionChanged.connect(
self._title_selection_changed)
box.layout().addWidget(self.title_var_view)
OWGUI.separator(self.controlArea)
self.fragmentSmilesCombo = OWGUI.comboBox(
self.controlArea,
self,
"fragmentSmilesAttr",
"Fragment SMILES Attribute",
callback=self.updateFragmentsListBox)
self.fragmentSmilesCombo.setModel(VariableListModel(parent=self))
self.fragmentSmilesCombo.box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
box = OWGUI.spin(self.controlArea,
self,
"imageSize",
50,
500,
10,
box="Image Size",
callback=self._image_size_changed)
box.setSizePolicy(QSizePolicy(QSizePolicy.Minimum,
QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Selection", addSpace=True)
OWGUI.checkBox(box, self, "commitOnChange", "Commit on change")
self.selectMarkedMoleculesButton = OWGUI.button(
box, self, "Select &matched molecules", self.select_marked)
OWGUI.button(box, self, "&Commit", callback=self.commit, default=True)
OWGUI.separator(self.controlArea)
OWGUI.rubber(self.controlArea)
spliter = QSplitter(Qt.Vertical)
self.scrollArea = ScrollArea(spliter)
self.grid = GridWidget()
self.grid.selectionChanged.connect(self._on_selection_changed)
self.scrollArea.setWidget(self.grid)
self.scrollArea.setWidgetResizable(True)
self.mainArea.layout().addWidget(spliter)
if pybel:
self.listBox = QListWidget(spliter)
else:
self.listBox = QListWidget(None)
self.listBox.setHidden(True)
self.listBox.itemClicked.connect(self.fragmentSelection)
self.fragmentSmilesCombo.box.setDisabled(not pybel)
self.data = None
self.data_subset = []
self.fragment_data = None
self.resize(800, 600)
self.listBox.setMaximumHeight(150)
self.fragmentSmilesCombo.setDisabled(True)
self.selectMarkedMoleculesButton.setDisabled(True)
self.markFragmentsCheckBox.setDisabled(True)
self.showFragmentsRadioButton.setDisabled(True)
self.loadSettings()
if not pybel:
self.showFragments = 0
self.warning(
10, "Pybel module not installed. To view molecule fragments\n"
"please install openbabel python extension.")
self.__loop = None
def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
OWWidget.__init__(self, parent, signalManager, name)
self.selectionChanged = False
self.filterString = ""
self.datasetName = ""
## GUI
box = gui.widgetBox(self.controlArea, "Info", addSpace=True)
self.infoBox = gui.widgetLabel(box, "Initializing\n\n")
box = gui.widgetBox(self.controlArea, "Output", addSpace=True)
gui.radioButtonsInBox(box,
self,
"outputRows",
["Genes in rows", "Samples in rows"],
"Rows",
callback=self.commitIf)
gui.checkBox(box,
self,
"mergeSpots",
"Merge spots of same gene",
callback=self.commitIf)
gui.separator(box)
self.nameEdit = gui.lineEdit(
box,
self,
"datasetName",
"Data set name",
tooltip="Override the default output data set name",
callback=self.onNameEdited)
self.nameEdit.setPlaceholderText("")
if sys.version_info < (3, ):
box = gui.widgetBox(self.controlArea, "Commit", addSpace=True)
self.commitButton = gui.button(box,
self,
"Commit",
callback=self.commit)
cb = gui.checkBox(box, self, "autoCommit", "Commit on any change")
gui.setStopper(self, self.commitButton, cb, "selectionChanged",
self.commit)
else:
gui.auto_commit(self.controlArea,
self,
"autoCommit",
"Commit",
box="Commit")
self.commitIf = self.commit
gui.rubber(self.controlArea)
gui.widgetLabel(self.mainArea, "Filter")
self.filterLineEdit = QLineEdit(textChanged=self.filter)
self.completer = TokenListCompleter(self,
caseSensitivity=Qt.CaseInsensitive)
self.filterLineEdit.setCompleter(self.completer)
self.mainArea.layout().addWidget(self.filterLineEdit)
splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(splitter)
self.treeWidget = QTreeView(splitter)
self.treeWidget.setSelectionMode(QTreeView.SingleSelection)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSortingEnabled(True)
self.treeWidget.setAlternatingRowColors(True)
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)
linkdelegate = LinkStyledItemDelegate(self.treeWidget)
self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
self.treeWidget.setItemDelegateForColumn(
0, gui.IndicatorItemDelegate(self.treeWidget, role=Qt.DisplayRole))
proxyModel = MySortFilterProxyModel(self.treeWidget)
self.treeWidget.setModel(proxyModel)
self.treeWidget.selectionModel().selectionChanged.connect(
self.updateSelection)
self.treeWidget.viewport().setMouseTracking(True)
splitterH = QSplitter(Qt.Horizontal, splitter)
box = gui.widgetBox(splitterH, "Description")
self.infoGDS = gui.widgetLabel(box, "")
self.infoGDS.setWordWrap(True)
gui.rubber(box)
box = gui.widgetBox(splitterH, "Sample Annotations")
self.annotationsTree = QTreeWidget(box)
self.annotationsTree.setHeaderLabels(
["Type (Sample annotations)", "Sample count"])
self.annotationsTree.setRootIsDecorated(True)
box.layout().addWidget(self.annotationsTree)
self.annotationsTree.itemChanged.connect(
self.annotationSelectionChanged)
self._annotationsUpdating = False
self.splitters = splitter, splitterH
for sp, setting in zip(self.splitters, self.splitterSettings):
sp.splitterMoved.connect(self.splitterMoved)
sp.restoreState(setting)
self.searchKeys = [
"dataset_id", "title", "platform_organism", "description"
]
self.gds = []
self.gds_info = None
self.resize(1000, 600)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._executor = ThreadExecutor()
func = partial(get_gds_model,
methodinvoke(self, "_setProgress", (float, )))
self._inittask = Task(function=func)
self._inittask.finished.connect(self._initializemodel)
self._executor.submit(self._inittask)
self._datatask = None
def __init__(self, parent=None, signalManager=None,
title="Molecule visualizer"):
super(OWMoleculeVisualizer, self).__init__(parent, signalManager, title)
self.colorFragments = 1
self.showFragments = 0
self.selectedFragment = ""
self.moleculeSmiles = []
self.fragmentSmiles = []
self.defFragmentSmiles = []
self.smiles_var = 0
self.moleculeTitleAttr = 0
self.moleculeTitleAttributeList = []
self.selectedMoleculeTitleAttrs = []
self.fragmentSmilesAttr = 0
self.imageSize = 200
self.numColumns = 4
self.commitOnChange = 0
## GUI
box = OWGUI.widgetBox(self.controlArea, "Info", addSpace=True)
self.infoLabel = OWGUI.label(box, self, "Chemicals:")
box = OWGUI.radioButtonsInBox(
self.controlArea, self, "showFragments",
["Show molecules", "Show fragments"], "Show",
callback=self.updateitems
)
self.showFragmentsRadioButton = box.buttons[-1]
self.markFragmentsCheckBox = OWGUI.checkBox(
box, self, "colorFragments", "Mark fragments",
callback=self._update
)
box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
self.moleculeSmilesCombo = OWGUI.comboBox(
self.controlArea, self, "smiles_var",
"Molecule SMILES Attribute",
callback=self.updateitems
)
self.moleculeSmilesCombo.box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum)
)
self.smiles_var_model = VariableListModel(parent=self)
self.moleculeSmilesCombo.setModel(self.smiles_var_model)
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Molecule Title Attributes",
addSpace=True)
self.title_var_view = QListView(
selectionMode=QListView.ExtendedSelection
)
self.title_var_model = VariableListModel(parent=self)
self.title_var_view.setModel(self.title_var_model)
self.title_var_view.selectionModel().selectionChanged.connect(
self._title_selection_changed
)
box.layout().addWidget(self.title_var_view)
OWGUI.separator(self.controlArea)
self.fragmentSmilesCombo = OWGUI.comboBox(
self.controlArea, self, "fragmentSmilesAttr",
"Fragment SMILES Attribute",
callback=self.updateFragmentsListBox
)
self.fragmentSmilesCombo.setModel(VariableListModel(parent=self))
self.fragmentSmilesCombo.box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum)
)
OWGUI.separator(self.controlArea)
box = OWGUI.spin(self.controlArea, self, "imageSize", 50, 500, 10,
box="Image Size", callback=self._image_size_changed)
box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Selection", addSpace=True)
OWGUI.checkBox(box, self, "commitOnChange", "Commit on change")
self.selectMarkedMoleculesButton = OWGUI.button(
box, self, "Select &matched molecules", self.select_marked
)
OWGUI.button(box, self, "&Commit", callback=self.commit, default=True)
OWGUI.separator(self.controlArea)
OWGUI.rubber(self.controlArea)
spliter = QSplitter(Qt.Vertical)
self.scrollArea = ScrollArea(spliter)
self.grid = GridWidget()
self.grid.selectionChanged.connect(self._on_selection_changed)
self.scrollArea.setWidget(self.grid)
self.scrollArea.setWidgetResizable(True)
self.mainArea.layout().addWidget(spliter)
if pybel:
self.listBox = QListWidget(spliter)
else:
self.listBox = QListWidget(None)
self.listBox.setHidden(True)
self.listBox.itemClicked.connect(self.fragmentSelection)
self.fragmentSmilesCombo.box.setDisabled(not pybel)
self.data = None
self.data_subset = []
self.fragment_data = None
self.resize(800, 600)
self.listBox.setMaximumHeight(150)
self.fragmentSmilesCombo.setDisabled(True)
self.selectMarkedMoleculesButton.setDisabled(True)
self.markFragmentsCheckBox.setDisabled(True)
self.showFragmentsRadioButton.setDisabled(True)
self.loadSettings()
if not pybel:
self.showFragments = 0
self.warning(10,
"Pybel module not installed. To view molecule fragments\n"
"please install openbabel python extension.")
self.__loop = None
