Exemplo n.º 1
0
def run_sim(number_neurons=default_number_neurons,
            connection_probability=default_connection_probability,
            synaptic_weights=default_synaptic_weights,
            synaptic_time_constant=default_synaptic_time_constant,
            tend=300):
    '''run a simulation of a population of leaky integrate-and-fire excitatory neurons that are
    randomly connected. The population is injected with a transient current.'''

    from brian.units import mvolt, msecond, namp, Mohm
    import brian
    brian.clear()

    El = 0 * mvolt
    tau_m = 30 * msecond
    tau_syn = synaptic_time_constant * msecond
    R = 20 * Mohm
    v_threshold = 30 * mvolt
    v_reset = 0 * mvolt
    tau_refractory = 4 * msecond

    eqs = brian.Equations('''
    dv/dt = (-(v - El) + R*I)/tau_m : volt
    I = I_syn + I_stim : amp
    dI_syn/dt = -I_syn/tau_syn : amp
    I_stim : amp
    ''')

    external_current = np.zeros(tend)
    external_current[np.arange(0, 100)] = 5 * namp

    group = brian.NeuronGroup(
        model=eqs,
        N=number_neurons, threshold=v_threshold, reset=v_reset, refractory=tau_refractory)

    group.I_stim = brian.TimedArray(external_current, dt=1*msecond)

    connections = brian.Connection(group, group, 'I_syn')
    connections.connect_random(sparseness=connection_probability, weight=synaptic_weights*namp)

    spike_monitor = brian.SpikeMonitor(group)
    population_rate_monitor = brian.PopulationRateMonitor(group, bin=10*msecond)

    brian.reinit()
    brian.run(tend * msecond)

    return spike_monitor, population_rate_monitor
def build_network():
    global fig_num

    neuron_groups['e'] = b.NeuronGroup(n_e_total, neuron_eqs_e, threshold=v_thresh_e, \
          refractory=refrac_e, reset=scr_e, compile=True, freeze=True)
    neuron_groups['i'] = b.NeuronGroup(n_e_total, neuron_eqs_i, threshold=v_thresh_i, \
         refractory=refrac_i, reset=v_reset_i, compile=True, freeze=True)

    for name in population_names:
        print '...Creating neuron group:', name

        # get a subgroup of size 'n_e' from all exc
        neuron_groups[name + 'e'] = neuron_groups['e'].subgroup(conv_features *
                                                                n_e)
        # get a subgroup of size 'n_i' from the inhibitory layer
        neuron_groups[name + 'i'] = neuron_groups['i'].subgroup(conv_features *
                                                                n_e)

        # start the membrane potentials of these groups 40mV below their resting potentials
        neuron_groups[name + 'e'].v = v_rest_e - 40. * b.mV
        neuron_groups[name + 'i'].v = v_rest_i - 40. * b.mV

    print '...Creating recurrent connections'

    for name in population_names:
        neuron_groups['e'].theta = np.load(
            os.path.join(best_weights_dir,
                         '_'.join(['theta_A', ending + '_best.npy'])))

        for conn_type in recurrent_conn_names:
            if conn_type == 'ei':
                # create connection name (composed of population and connection types)
                conn_name = name + conn_type[0] + name + conn_type[1]
                # create a connection from the first group in conn_name with the second group
                connections[conn_name] = b.Connection(
                    neuron_groups[conn_name[0:2]],
                    neuron_groups[conn_name[2:4]],
                    structure='sparse',
                    state='g' + conn_type[0])

                # instantiate the created connection
                for feature in xrange(conv_features):
                    for n in xrange(n_e):
                        connections[conn_name][feature * n_e + n,
                                               feature * n_e + n] = 10.4

            elif conn_type == 'ie':
                # create connection name (composed of population and connection types)
                conn_name = name + conn_type[0] + name + conn_type[1]

                # load weight matrix
                weight_matrix = np.load(
                    os.path.join(best_weights_dir,
                                 '_'.join([conn_name, ending, 'best.npy'])))

                # create a connection from the first group in conn_name with the second group
                connections[conn_name] = b.Connection(
                    neuron_groups[conn_name[0:2]],
                    neuron_groups[conn_name[2:4]],
                    structure='sparse',
                    state='g' + conn_type[0])

                # define the actual synaptic connections and strengths
                for feature in xrange(conv_features):
                    for other_feature in xrange(conv_features):
                        if feature != other_feature:
                            for n in xrange(n_e):
                                connections[conn_name][feature * n_e + n,
                                                       other_feature * n_e +
                                                       n] = inhibition_level

        print '...Creating monitors for:', name

        # spike rate monitors for excitatory and inhibitory neuron populations
        rate_monitors[name + 'e'] = b.PopulationRateMonitor(
            neuron_groups[name + 'e'],
            bin=(single_example_time + resting_time) / b.second)
        rate_monitors[name + 'i'] = b.PopulationRateMonitor(
            neuron_groups[name + 'i'],
            bin=(single_example_time + resting_time) / b.second)
        spike_counters[name + 'e'] = b.SpikeCounter(neuron_groups[name + 'e'])

        # record neuron population spikes if specified
        if record_spikes and do_plot:
            spike_monitors[name + 'e'] = b.SpikeMonitor(neuron_groups[name +
                                                                      'e'])
            spike_monitors[name + 'i'] = b.SpikeMonitor(neuron_groups[name +
                                                                      'i'])

    if record_spikes and do_plot:
        b.figure(fig_num, figsize=(8, 6))
        b.ion()
        b.subplot(211)
        b.raster_plot(spike_monitors['Ae'],
                      refresh=1000 * b.ms,
                      showlast=1000 * b.ms,
                      title='Excitatory spikes per neuron')
        b.subplot(212)
        b.raster_plot(spike_monitors['Ai'],
                      refresh=1000 * b.ms,
                      showlast=1000 * b.ms,
                      title='Inhibitory spikes per neuron')
        b.tight_layout()

        fig_num += 1

    # creating Poission spike train from input image (784 vector, 28x28 image)
    for name in input_population_names:
        input_groups[name + 'e'] = b.PoissonGroup(n_input, 0)
        rate_monitors[name + 'e'] = b.PopulationRateMonitor(
            input_groups[name + 'e'],
            bin=(single_example_time + resting_time) / b.second)

    # creating connections from input Poisson spike train to excitatory neuron population(s)
    for name in input_connection_names:
        print '\n...Creating connections between', name[0], 'and', name[1]

        # for each of the input connection types (in this case, excitatory -> excitatory)
        for conn_type in input_conn_names:
            # saved connection name
            conn_name = name[0] + conn_type[0] + name[1] + conn_type[1]

            # get weight matrix depending on training or test phase
            weight_matrix = np.load(
                os.path.join(best_weights_dir,
                             '_'.join([conn_name, ending + '_best.npy'])))

            # create connections from the windows of the input group to the neuron population
            input_connections[conn_name] = b.Connection(input_groups['Xe'], neuron_groups[name[1] + conn_type[1]], \
                structure='sparse', state='g' + conn_type[0], delay=True, max_delay=delay[conn_type][1])

            for feature in xrange(conv_features):
                for n in xrange(n_e):
                    for idx in xrange(conv_size**2):
                        input_connections[conn_name][convolution_locations[n][idx], feature * n_e + n] = \
                                weight_matrix[convolution_locations[n][idx], feature * n_e + n]

            if do_plot:
                plot_2d_input_weights()
                fig_num += 1

    print '\n'
Exemplo n.º 3
0
                                      neuron_groups[connName[2:4]],
                                      weightMatrix)

    if ee_STDP_on:
        if 'ee' in recurrent_conn_names:
            stdp_methods[name + 'e' + name + 'e'] = b.STDP(
                connections[name + 'e' + name + 'e' + ending],
                eqs=eqs_stdp_ee,
                pre=eqs_stdp_pre_ee,
                post=eqs_stdp_post_ee,
                wmin=0.,
                wmax=wmax_ee)

    print 'create monitors for', name
    rate_monitors[name + 'e'] = b.PopulationRateMonitor(
        neuron_groups[name + 'e'],
        bin=(single_example_time + resting_time) / b.second)
    rate_monitors[name + 'i'] = b.PopulationRateMonitor(
        neuron_groups[name + 'i'],
        bin=(single_example_time + resting_time) / b.second)
    spike_counters[name + 'e'] = b.SpikeCounter(neuron_groups[name + 'e'])

    if record_spikes:
        spike_monitors[name + 'e'] = b.SpikeMonitor(neuron_groups[name + 'e'])
        spike_monitors[name + 'i'] = b.SpikeMonitor(neuron_groups[name + 'i'])

if record_spikes:
    b.figure(fig_num)
    fig_num += 1
    b.ion()
    b.subplot(211)
	def __init__(mode, connectivity, weight_dependence, post_pre, conv_size, conv_stride, conv_features, weight_sharing, lattice_structure, random_inhibition_prob, top_percent):
		'''
		Network initialization.
		'''

		# setting input parameters
		this.mode = mode
		this.connectivity = connectivity
		this.weight_dependence = weight_dependence
		this.post_pre = post_pre
		this.conv_size = conv_size
		this.conv_features = conv_features
		this.weight_sharing = weight_sharing
		this.lattice_structure = lattice_structure
		this.random_inhibition_prob = random_inhibition_prob

		# load training or testing data
		if mode == 'train':
		    start = time.time()
		    this.data = get_labeled_data(MNIST_data_path + 'training')
		    end = time.time()
		    print 'time needed to load training set:', end - start
		else:
		    start = time.time()
		    this.data = get_labeled_data(MNIST_data_path + 'testing', bTrain = False)
		    end = time.time()
		    print 'time needed to load test set:', end - start

		# set parameters for simulation based on train / test mode
		if test_mode:
			weight_path = top_level_path + 'weights/conv_patch_connectivity_weights/'
			this.num_examples = 10000 * 1
			this.do_plot_performance = False
			ee_STDP_on = False
		else:
			weight_path = top_level_path + 'random/conv_patch_connectivity_random/'
			this.num_examples = 60000 * 1
			this.do_plot_performance = True
			ee_STDP_on = True

		# plotting or not
		do_plot = True

		# number of inputs to the network
		this.n_input = 784
		this.n_input_sqrt = int(math.sqrt(n_input))

		# number of neurons parameters
		this.n_e = ((n_input_sqrt - conv_size) / conv_stride + 1) ** 2
		this.n_e_total = n_e * conv_features
		this.n_e_sqrt = int(math.sqrt(n_e))
		this.n_i = n_e
		this.conv_features_sqrt = int(math.sqrt(conv_features))

		# time (in seconds) per data example presentation and rest period in between, used to calculate total runtime
		this.single_example_time = 0.35 * b.second
		this.resting_time = 0.15 * b.second
		runtime = num_examples * (single_example_time + resting_time)

		# set the update interval
		if test_mode:
			this.update_interval = num_examples
		else:
			this.update_interval = 100

		# rest potential parameters, reset potential parameters, threshold potential parameters, and refractory periods
		v_rest_e, v_rest_i = -65. * b.mV, -60. * b.mV
		v_reset_e, v_reset_i = -65. * b.mV, -45. * b.mV
		v_thresh_e, v_thresh_i = -52. * b.mV, -40. * b.mV
		refrac_e, refrac_i = 5. * b.ms, 2. * b.ms

		# dictionaries for weights and delays
		weight, delay = {}, {}

		# populations, connections, saved connections, etc.
		input_population_names = [ 'X' ]
		population_names = [ 'A' ]
		input_connection_names = [ 'XA' ]
		save_conns = [ 'XeAe', 'AeAe' ]

		# weird and bad names for variables, I think
		input_conn_names = [ 'ee_input' ]
		recurrent_conn_names = [ 'ei', 'ie', 'ee' ]
		
		# setting weight, delay, and intensity parameters
		weight['ee_input'] = (conv_size ** 2) * 0.175
		delay['ee_input'] = (0 * b.ms, 10 * b.ms)
		delay['ei_input'] = (0 * b.ms, 5 * b.ms)
		input_intensity = start_input_intensity = 2.0

		# time constants, learning rates, max weights, weight dependence, etc.
		tc_pre_ee, tc_post_ee = 20 * b.ms, 20 * b.ms
		nu_ee_pre, nu_ee_post = 0.0001, 0.01
		wmax_ee = 1.0
		exp_ee_post = exp_ee_pre = 0.2
		w_mu_pre, w_mu_post = 0.2, 0.2

		# setting up differential equations (depending on train / test mode)
		if test_mode:
			scr_e = 'v = v_reset_e; timer = 0*ms'
		else:
			tc_theta = 1e7 * b.ms
			theta_plus_e = 0.05 * b.mV
			scr_e = 'v = v_reset_e; theta += theta_plus_e; timer = 0*ms'

		offset = 20.0 * b.mV
		v_thresh_e = '(v>(theta - offset + ' + str(v_thresh_e) + ')) * (timer>refrac_e)'

		# equations for neurons
		neuron_eqs_e = '''
				dv/dt = ((v_rest_e - v) + (I_synE + I_synI) / nS) / (100 * ms)  : volt
				I_synE = ge * nS *         -v                           : amp
				I_synI = gi * nS * (-100.*mV-v)                          : amp
				dge/dt = -ge/(1.0*ms)                                   : 1
				dgi/dt = -gi/(2.0*ms)                                  : 1
				'''
		if test_mode:
			neuron_eqs_e += '\n  theta      :volt'
		else:
			neuron_eqs_e += '\n  dtheta/dt = -theta / (tc_theta)  : volt'

		neuron_eqs_e += '\n  dtimer/dt = 100.0 : ms'

		neuron_eqs_i = '''
				dv/dt = ((v_rest_i - v) + (I_synE + I_synI) / nS) / (10*ms)  : volt
				I_synE = ge * nS *         -v                           : amp
				I_synI = gi * nS * (-85.*mV-v)                          : amp
				dge/dt = -ge/(1.0*ms)                                   : 1
				dgi/dt = -gi/(2.0*ms)                                  : 1
				'''

		# creating dictionaries for various objects
		this.neuron_groups = {}
		this.input_groups = {}
		this.connections = {}
		this.input_connections = {}
		this.stdp_methods = {}
		this.rate_monitors = {}
		this.spike_monitors = {}
		this.spike_counters = {}

		# creating excitatory, inhibitory populations
		this.neuron_groups['e'] = b.NeuronGroup(n_e_total, neuron_eqs_e, threshold=v_thresh_e, refractory=refrac_e, reset=scr_e, compile=True, freeze=True)
		this.neuron_groups['i'] = b.NeuronGroup(n_e_total, neuron_eqs_i, threshold=v_thresh_i, refractory=refrac_i, reset=v_reset_i, compile=True, freeze=True)

		# creating subpopulations of excitatory, inhibitory neurons
		for name in population_names:
			print '...creating neuron group:', name

			# get a subgroup of size 'n_e' from all exc
			neuron_groups[name + 'e'] = neuron_groups['e'].subgroup(conv_features * n_e)
			# get a subgroup of size 'n_i' from the inhibitory layer
			neuron_groups[name + 'i'] = neuron_groups['i'].subgroup(conv_features * n_e)

			# start the membrane potentials of these groups 40mV below their resting potentials
			neuron_groups[name + 'e'].v = v_rest_e - 40. * b.mV
			neuron_groups[name + 'i'].v = v_rest_i - 40. * b.mV

		print '...creating recurrent connections'

		for name in population_names:
			# if we're in test mode / using some stored weights
			if mode == 'test' or weight_path[-8:] == 'weights/conv_patch_connectivity_weights/':
				# load up adaptive threshold parameters
				neuron_groups['e'].theta = np.load(weight_path + 'theta_A' + '_' + ending +'.npy')
			else:
				# otherwise, set the adaptive additive threshold parameter at 20mV
				neuron_groups['e'].theta = np.ones((n_e_total)) * 20.0 * b.mV

			for conn_type in recurrent_conn_names:
				if conn_type == 'ei':
					# create connection name (composed of population and connection types)
					conn_name = name + conn_type[0] + name + conn_type[1]
					# create a connection from the first group in conn_name with the second group
					connections[conn_name] = b.Connection(neuron_groups[conn_name[0:2]], neuron_groups[conn_name[2:4]], structure='sparse', state='g' + conn_type[0])
					# instantiate the created connection
					for feature in xrange(conv_features):
						for n in xrange(n_e):
							connections[conn_name][feature * n_e + n, feature * n_e + n] = 10.4

				elif conn_type == 'ie':
					# create connection name (composed of population and connection types)
					conn_name = name + conn_type[0] + name + conn_type[1]
					# create a connection from the first group in conn_name with the second group
					connections[conn_name] = b.Connection(neuron_groups[conn_name[0:2]], neuron_groups[conn_name[2:4]], structure='sparse', state='g' + conn_type[0])
					# instantiate the created connection
					for feature in xrange(conv_features):
						for other_feature in xrange(conv_features):
							if feature != other_feature:
								for n in xrange(n_e):
									connections[conn_name][feature * n_e + n, other_feature * n_e + n] = 17.4

					if random_inhibition_prob != 0.0:
						for feature in xrange(conv_features):
							for other_feature in xrange(conv_features):
								for n_this in xrange(n_e):
									for n_other in xrange(n_e):
										if n_this != n_other:
											if b.random() < random_inhibition_prob:
												connections[conn_name][feature * n_e + n_this, other_feature * n_e + n_other] = 17.4

				elif conn_type == 'ee':
					# create connection name (composed of population and connection types)
					conn_name = name + conn_type[0] + name + conn_type[1]
					# get weights from file if we are in test mode
					if mode == 'test':
						weight_matrix = get_matrix_from_file(weight_path + conn_name + '_' + ending + '.npy', conv_features * n_e, conv_features * n_e)
					# create a connection from the first group in conn_name with the second group
					connections[conn_name] = b.Connection(neuron_groups[conn_name[0:2]], neuron_groups[conn_name[2:4]], structure='sparse', state='g' + conn_type[0])
					# instantiate the created connection
					if connectivity == 'all':
						for feature in xrange(conv_features):
							for other_feature in xrange(conv_features):
								if feature != other_feature:
									for this_n in xrange(n_e):
										for other_n in xrange(n_e):
											if is_lattice_connection(n_e_sqrt, this_n, other_n):
												if mode == 'test':
													connections[conn_name][feature * n_e + this_n, other_feature * n_e + other_n] = weight_matrix[feature * n_e + this_n, other_feature * n_e + other_n]
												else:
													connections[conn_name][feature * n_e + this_n, other_feature * n_e + other_n] = (b.random() + 0.01) * 0.3

					elif connectivity == 'pairs':
						for feature in xrange(conv_features):
							if feature % 2 == 0:
								for this_n in xrange(n_e):
									for other_n in xrange(n_e):
										if is_lattice_connection(n_e_sqrt, this_n, other_n):
											if mode == 'test':
												connections[conn_name][feature * n_e + this_n, (feature + 1) * n_e + other_n] = weight_matrix[feature * n_e + this_n, (feature + 1) * n_e + other_n]
											else:
												connections[conn_name][feature * n_e + this_n, (feature + 1) * n_e + other_n] = (b.random() + 0.01) * 0.3
							elif feature % 2 == 1:
								for this_n in xrange(n_e):
									for other_n in xrange(n_e):
										if is_lattimode == 'test'ce_connection(n_e_sqrt, this_n, other_n):
											if mode == 'test':
												connections[conn_name][feature * n_e + this_n, (feature - 1) * n_e + other_n] = weight_matrix[feature * n_e + this_n, (feature - 1) * n_e + other_n]
											else:
												connections[conn_name][feature * n_e + this_n, (feature - 1) * n_e + other_n] = (b.random() + 0.01) * 0.3

					elif connectivity == 'none':
						pass

			# if STDP from excitatory -> excitatory is on and this connection is excitatory -> excitatory
			if ee_STDP_on and 'ee' in recurrent_conn_names:
				stdp_methods[name + 'e' + name + 'e'] = b.STDP(connections[name + 'e' + name + 'e'], eqs=eqs_stdp_ee, pre=eqs_stdp_pre_ee, post=eqs_stdp_post_ee, wmin=0., wmax=wmax_ee)

			print '...creating monitors for:', name

			# spike rate monitors for excitatory and inhibitory neuron populations
			rate_monitors[name + 'e'] = b.PopulationRateMonitor(neuron_groups[name + 'e'], bin=(single_example_time + resting_time) / b.second)
			rate_monitors[name + 'i'] = b.PopulationRateMonitor(neuron_groups[name + 'i'], bin=(single_example_time + resting_time) / b.second)
			spike_counters[name + 'e'] = b.SpikeCounter(neuron_groups[name + 'e'])

			# record neuron population spikes if specified
			spike_monitors[name + 'e'] = b.SpikeMonitor(neuron_groups[name + 'e'])
			spike_monitors[name + 'i'] = b.SpikeMonitor(neuron_groups[name + 'i'])
Exemplo n.º 5
0
def build_network():
    global fig_num, assignments

    neuron_groups['e'] = b.NeuronGroup(n_e_total,
                                       neuron_eqs_e,
                                       threshold=v_thresh_e,
                                       refractory=refrac_e,
                                       reset=scr_e,
                                       compile=True,
                                       freeze=True)
    neuron_groups['i'] = b.NeuronGroup(n_e_total,
                                       neuron_eqs_i,
                                       threshold=v_thresh_i,
                                       refractory=refrac_i,
                                       reset=v_reset_i,
                                       compile=True,
                                       freeze=True)

    for name in population_names:
        print '...Creating neuron group:', name

        # get a subgroup of size 'n_e' from all exc
        neuron_groups[name + 'e'] = neuron_groups['e'].subgroup(conv_features *
                                                                n_e)
        # get a subgroup of size 'n_i' from the inhibitory layer
        neuron_groups[name + 'i'] = neuron_groups['i'].subgroup(conv_features *
                                                                n_e)

        # start the membrane potentials of these groups 40mV below their resting potentials
        neuron_groups[name + 'e'].v = v_rest_e - 40. * b.mV
        neuron_groups[name + 'i'].v = v_rest_i - 40. * b.mV

    print '...Creating recurrent connections'

    for name in population_names:
        # if we're in test mode / using some stored weights
        if test_mode:
            # load up adaptive threshold parameters
            if save_best_model:
                neuron_groups['e'].theta = np.load(
                    os.path.join(best_weights_dir,
                                 '_'.join(['theta_A', ending + '_best.npy'])))
            else:
                neuron_groups['e'].theta = np.load(
                    os.path.join(end_weights_dir,
                                 '_'.join(['theta_A', ending + '_end.npy'])))
        else:
            # otherwise, set the adaptive additive threshold parameter at 20mV
            neuron_groups['e'].theta = np.ones((n_e_total)) * 20.0 * b.mV

        for conn_type in recurrent_conn_names:
            if conn_type == 'ei':
                # create connection name (composed of population and connection types)
                conn_name = name + conn_type[0] + name + conn_type[1]
                # create a connection from the first group in conn_name with the second group
                connections[conn_name] = b.Connection(
                    neuron_groups[conn_name[0:2]],
                    neuron_groups[conn_name[2:4]],
                    structure='sparse',
                    state='g' + conn_type[0])

                # instantiate the created connection
                for feature in xrange(conv_features):
                    for n in xrange(n_e):
                        connections[conn_name][feature * n_e + n,
                                               feature * n_e + n] = 10.4

            elif conn_type == 'ie':
                # create connection name (composed of population and connections types)
                conn_name = name + conn_type[0] + name + conn_type[
                    1] + '_' + ending
                # create a connection from the first group in conn_name with the second group
                connections[conn_name] = b.Connection(
                    neuron_groups[conn_name[0:2]],
                    neuron_groups[conn_name[2:4]],
                    structure='sparse',
                    state='g' + conn_type[0])
                # instantiate the created connection with the 'weightMatrix' loaded from file
                for feature in xrange(conv_features):
                    for other_feature in xrange(conv_features):
                        if feature != other_feature:
                            for n in xrange(n_e):
                                connections[conn_name][feature * n_e + n,
                                                       other_feature * n_e +
                                                       n] = 17.4

        print '...Creating monitors for:', name

        # spike rate monitors for excitatory and inhibitory neuron populations
        rate_monitors[name + 'e'] = b.PopulationRateMonitor(
            neuron_groups[name + 'e'],
            bin=(single_example_time + resting_time) / b.second)
        rate_monitors[name + 'i'] = b.PopulationRateMonitor(
            neuron_groups[name + 'i'],
            bin=(single_example_time + resting_time) / b.second)
        spike_counters[name + 'e'] = b.SpikeCounter(neuron_groups[name + 'e'])

        # record neuron population spikes if specified
        if record_spikes or plot:
            spike_monitors[name + 'e'] = b.SpikeMonitor(neuron_groups[name +
                                                                      'e'])
            spike_monitors[name + 'i'] = b.SpikeMonitor(neuron_groups[name +
                                                                      'i'])

    if record_spikes and plot:
        b.figure(fig_num, figsize=(8, 6))

        fig_num += 1

        b.ion()
        b.subplot(211)
        b.raster_plot(spike_monitors['Ae'],
                      refresh=1000 * b.ms,
                      showlast=1000 * b.ms,
                      title='Excitatory spikes per neuron')
        b.subplot(212)
        b.raster_plot(spike_monitors['Ai'],
                      refresh=1000 * b.ms,
                      showlast=1000 * b.ms,
                      title='Inhibitory spikes per neuron')
        b.tight_layout()

    # creating Poission spike train from input image (784 vector, 28x28 image)
    for name in input_population_names:
        input_groups[name + 'e'] = b.PoissonGroup(n_input, 0)
        rate_monitors[name + 'e'] = b.PopulationRateMonitor(
            input_groups[name + 'e'],
            bin=(single_example_time + resting_time) / b.second)

    # creating connections from input Poisson spike train to excitatory neuron population(s)
    for name in input_connection_names:
        print '\n...Creating connections between', name[0], 'and', name[1]

        # for each of the input connection types (in this case, excitatory -> excitatory)
        for conn_type in input_conn_names:
            # saved connection name
            conn_name = name[0] + conn_type[0] + name[1] + conn_type[1]

            # get weight matrix depending on training or test phase
            if test_mode:
                if save_best_model:
                    weight_matrix = np.load(
                        os.path.join(
                            best_weights_dir,
                            '_'.join([conn_name, ending + '_best.npy'])))
                else:
                    weight_matrix = np.load(
                        os.path.join(
                            end_weights_dir,
                            '_'.join([conn_name, ending + '_end.npy'])))

            # create connections from the windows of the input group to the neuron population
            input_connections[conn_name] = b.Connection(input_groups['Xe'], neuron_groups[name[1] + conn_type[1]], \
                structure='sparse', state='g' + conn_type[0], delay=True, max_delay=delay[conn_type][1])

            if test_mode:
                for feature in xrange(conv_features):
                    for n in xrange(n_e):
                        for idx in xrange(conv_size**2):
                            input_connections[conn_name][convolution_locations[n][idx], feature * n_e + n] = \
                                    weight_matrix[convolution_locations[n][idx], feature * n_e + n]
            else:
                for feature in xrange(conv_features):
                    for n in xrange(n_e):
                        for idx in xrange(conv_size**2):
                            input_connections[conn_name][
                                convolution_locations[n][idx],
                                feature * n_e + n] = (b.random() + 0.01) * 0.3

            if test_mode:
                if plot:
                    plot_weights_and_assignments(assignments)
                    fig_num += 1

        # if excitatory -> excitatory STDP is specified, add it here (input to excitatory populations)
        if not test_mode:
            print '...Creating STDP for connection', name

            # STDP connection name
            conn_name = name[0] + conn_type[0] + name[1] + conn_type[1]
            # create the STDP object
            stdp_methods[conn_name] = b.STDP(input_connections[conn_name], eqs=eqs_stdp_ee, \
                pre=eqs_stdp_pre_ee, post=eqs_stdp_post_ee, wmin=0., wmax=wmax_ee)

    print '\n'
Exemplo n.º 6
0
    def __init__(self,
                 n_input=784,
                 conv_size=16,
                 conv_stride=4,
                 conv_features=50,
                 connectivity='all',
                 weight_dependence=False,
                 post_pre=True,
                 weight_sharing=False,
                 lattice_structure='4',
                 random_lattice_prob=0.0,
                 random_inhibition_prob=0.0):
        '''
		Constructor for the spiking convolutional neural network model.

		n_input: (flattened) dimensionality of the input data
		conv_size: side length of convolution windows used
		conv_stride: stride (horizontal and vertical) of convolution windows used
		conv_features: number of convolution features (or patches) used
		connectivity: connection style between patches; one of 'none', 'pairs', all'; more to be added
		weight_dependence: whether to use weight STDP with weight dependence
		post_pre: whether to use STDP with both post- and pre-synpatic traces
		weight_sharing: whether to impose that all neurons within a convolution patch share a common set of weights
		lattice_structure: lattice connectivity pattern between patches; one of 'none', '4', '8', and 'all'
		random_lattice_prob: probability of adding random additional lattice connections between patches
		random_inhibition_prob: probability of adding random additional inhibition edges from the inhibitory to excitatory population
		'''
        self.n_input, self.conv_size, self.conv_stride, self.conv_features, self.connectivity, self.weight_dependence, \
         self.post_pre, self.weight_sharing, self.lattice_structure, self.random_lattice_prob, self.random_inhibition_prob = \
         n_input, conv_size, conv_stride, conv_features, connectivity, weight_dependence, post_pre, weight_sharing, lattice_structure, \
         random_lattice_prob, random_inhibition_prob

        # number of inputs to the network
        self.n_input_sqrt = int(math.sqrt(self.n_input))
        self.n_excitatory_patch = (
            (self.n_input_sqrt - self.conv_size) / self.conv_stride + 1)**2
        self.n_excitatory = self.n_excitatory_patch * self.conv_features
        self.n_excitatory_patch_sqrt = int(math.sqrt(self.n_excitatory_patch))
        self.n_inhibitory_patch = self.n_excitatory_patch
        self.n_inhibitory = self.n_excitatory
        self.conv_features_sqrt = int(math.ceil(math.sqrt(self.conv_features)))

        # time (in seconds) per data example presentation and rest period in between
        self.single_example_time = 0.35 * b.second
        self.resting_time = 0.15 * b.second

        # set update intervals
        self.update_interval = 100
        self.weight_update_interval = 10
        self.print_progress_interval = 10

        # rest potential parameters, reset potential parameters, threshold potential parameters, and refractory periods
        v_rest_e, v_rest_i = -65. * b.mV, -60. * b.mV
        v_reset_e, v_reset_i = -65. * b.mV, -45. * b.mV
        v_thresh_e, v_thresh_i = -52. * b.mV, -40. * b.mV
        refrac_e, refrac_i = 5. * b.ms, 2. * b.ms

        # time constants, learning rates, max weights, weight dependence, etc.
        tc_pre_ee, tc_post_ee = 20 * b.ms, 20 * b.ms
        nu_ee_pre, nu_ee_post = 0.0001, 0.01
        exp_ee_post = exp_ee_pre = 0.2
        w_mu_pre, w_mu_post = 0.2, 0.2

        # parameters for neuron equations
        tc_theta = 1e7 * b.ms
        theta_plus = 0.05 * b.mV
        scr_e = 'v = v_reset_e; theta += theta_plus; timer = 0*ms'
        offset = 20.0 * b.mV
        v_thresh_e = '(v>(theta - offset + ' + str(
            v_thresh_e) + ')) * (timer>refrac_e)'

        # equations for neurons
        neuron_eqs_e = '''
				dv / dt = ((v_rest_e - v) + (I_synE + I_synI) / nS) / (100 * ms)  : volt
				I_synE = ge * nS * - v  : amp
				I_synI = gi * nS * (-100. * mV - v)  : amp
				dge / dt = -ge / (1.0*ms)  : 1
				dgi / dt = -gi / (2.0*ms)  : 1
				dtheta / dt = -theta / (tc_theta)  : volt
				dtimer / dt = 100.0  : ms
			'''

        neuron_eqs_i = '''
				dv/dt = ((v_rest_i - v) + (I_synE + I_synI) / nS) / (10*ms)  : volt
				I_synE = ge * nS *         -v                           : amp
				I_synI = gi * nS * (-85.*mV-v)                          : amp
				dge/dt = -ge/(1.0*ms)                                   : 1
				dgi/dt = -gi/(2.0*ms)                                  : 1
			'''

        # STDP synaptic traces
        eqs_stdp_ee = '''
				dpre / dt = -pre / tc_pre_ee : 1.0
				dpost / dt = -post / tc_post_ee : 1.0
			'''

        # dictionaries for weights and delays
        self.weight, self.delay = {}, {}

        # setting weight, delay, and intensity parameters
        self.weight['ee_input'] = (conv_size**2) * 0.175
        self.delay['ee_input'] = (0 * b.ms, 10 * b.ms)
        self.delay['ei_input'] = (0 * b.ms, 5 * b.ms)
        self.input_intensity = self.start_input_intensity = 2.0
        self.wmax_ee = 1.0

        # populations, connections, saved connections, etc.
        self.input_population_names = ['X']
        self.population_names = ['A']
        self.input_connection_names = ['XA']
        self.save_connections = ['XeAe', 'AeAe']
        self.input_connection_names = ['ee_input']
        self.recurrent_connection_names = ['ei', 'ie', 'ee']

        # setting STDP update rule
        if weight_dependence:
            if post_pre:
                eqs_stdp_pre_ee = 'pre = 1.; w -= nu_ee_pre * post * w ** exp_ee_pre'
                eqs_stdp_post_ee = 'w += nu_ee_post * pre * (wmax_ee - w) ** exp_ee_post; post = 1.'

            else:
                eqs_stdp_pre_ee = 'pre = 1.'
                eqs_stdp_post_ee = 'w += nu_ee_post * pre * (wmax_ee - w) ** exp_ee_post; post = 1.'

        else:
            if post_pre:
                eqs_stdp_pre_ee = 'pre = 1.; w -= nu_ee_pre * post'
                eqs_stdp_post_ee = 'w += nu_ee_post * pre; post = 1.'

            else:
                eqs_stdp_pre_ee = 'pre = 1.'
                eqs_stdp_post_ee = 'w += nu_ee_post * pre; post = 1.'

        print '\n'

        # for filesaving purposes
        stdp_input = ''
        if self.weight_dependence:
            stdp_input += 'weight_dependence_'
        else:
            stdp_input += 'no_weight_dependence_'
        if self.post_pre:
            stdp_input += 'post_pre'
        else:
            stdp_input += 'no_post_pre'
        if self.weight_sharing:
            use_weight_sharing = 'weight_sharing'
        else:
            use_weight_sharing = 'no_weight_sharing'

        # set ending of filename saves
        self.ending = self.connectivity + '_' + str(self.conv_size) + '_' + str(self.conv_stride) + '_' + str(self.conv_features) + \
             '_' + str(self.n_excitatory_patch) + '_' + stdp_input + '_' + \
             use_weight_sharing + '_' + str(self.lattice_structure) + '_' + str(self.random_lattice_prob) + \
             '_' + str(self.random_inhibition_prob)

        self.fig_num = 1

        # creating dictionaries for various objects
        self.neuron_groups, self.input_groups, self.connections, self.input_connections, self.stdp_methods, self.rate_monitors, \
         self.spike_monitors, self.spike_counters, self.output_numbers = {}, {}, {}, {}, {}, {}, {}, {}, {}

        # creating convolution locations inside the input image
        self.convolution_locations = {}
        for n in xrange(self.n_excitatory_patch):
            self.convolution_locations[n] = [ ((n % self.n_excitatory_patch_sqrt) * self.conv_stride + (n // self.n_excitatory_patch_sqrt) \
                      * self.n_input_sqrt * self.conv_stride) + (x * self.n_input_sqrt) + y \
                      for y in xrange(self.conv_size) for x in xrange(self.conv_size) ]

        # instantiating neuron spike / votes monitor
        self.result_monitor = np.zeros(
            (self.update_interval, self.conv_features,
             self.n_excitatory_patch))

        # creating overarching neuron populations
        self.neuron_groups['e'] = b.NeuronGroup(self.n_excitatory, neuron_eqs_e, threshold=v_thresh_e, \
                     refractory=refrac_e, reset=scr_e, compile=True, freeze=True)
        self.neuron_groups['i'] = b.NeuronGroup(self.n_inhibitory, neuron_eqs_i, threshold=v_thresh_i, \
                     refractory=refrac_i, reset=v_reset_i, compile=True, freeze=True)

        # create neuron subpopulations
        for name in self.population_names:
            print '...creating neuron group:', name

            # get a subgroup of size 'n_e' from all exc
            self.neuron_groups[name + 'e'] = self.neuron_groups['e'].subgroup(
                self.conv_features * self.n_excitatory_patch)
            # get a subgroup of size 'n_i' from the inhibitory layer
            self.neuron_groups[name + 'i'] = self.neuron_groups['i'].subgroup(
                self.conv_features * self.n_excitatory_patch)

            # start the membrane potentials of these groups 40mV below their resting potentials
            self.neuron_groups[name + 'e'].v = v_rest_e - 40. * b.mV
            self.neuron_groups[name + 'i'].v = v_rest_i - 40. * b.mV

        print '...creating recurrent connections'

        for name in self.population_names:
            # set the adaptive additive threshold parameter at 20mV
            self.neuron_groups['e'].theta = np.ones(
                (self.n_excitatory)) * 20.0 * b.mV

            for connection_type in self.recurrent_connection_names:
                if connection_type == 'ei':
                    # create connection name (composed of population and connection types)
                    connection_name = name + connection_type[
                        0] + name + connection_type[1]
                    # create a connection from the first group in conn_name with the second group
                    self.connections[connection_name] = b.Connection(self.neuron_groups[connection_name[0:2]], \
                            self.neuron_groups[connection_name[2:4]], structure='sparse', state='g' + conn_type[0])
                    # instantiate the created connection
                    for feature in xrange(self.conv_features):
                        for n in xrange(self.n_excitatory_patch):
                            self.connections[conn_name][feature * self.n_excitatory_patch + n, \
                                    feature * self.n_excitatory_patch + n] = 10.4

                elif connection_type == 'ie':
                    # create connection name (composed of population and connection types)
                    connection_name = name + connection_type[
                        0] + name + connection_type[1]
                    # create a connection from the first group in conn_name with the second group
                    self.connections[connection_name] = b.Connection(self.neuron_groups[connection_name[0:2]], \
                            self.neuron_groups[connection_name[2:4]], structure='sparse', state='g' + conn_type[0])
                    # instantiate the created connection
                    for feature in xrange(self.conv_features):
                        for other_feature in xrange(self.conv_features):
                            if feature != other_feature:
                                for n in xrange(self.n_excitatory_patch):
                                    self.connections[connection_name][feature * self.n_excitatory_patch + n, \
                                          other_feature * self.n_excitatory_patch + n] = 17.4

                    # adding random inhibitory connections as specified
                    if self.random_inhibition_prob != 0.0:
                        for feature in xrange(self.conv_features):
                            for other_feature in xrange(self.conv_features):
                                for n_this in xrange(self.n_excitatory_patch):
                                    for n_other in xrange(
                                            self.n_excitatory_patch):
                                        if n_this != n_other:
                                            if b.random(
                                            ) < self.random_inhibition_prob:
                                                self.connections[connection_name][feature * self.n_excitatory_patch + n_this, \
                                                  other_feature * self.n_excitatory_patch + n_other] = 17.4

                elif connection_type == 'ee':
                    # create connection name (composed of population and connection types)
                    connection_name = name + connection_type[
                        0] + name + connection_type[1]
                    # create a connection from the first group in conn_name with the second group
                    self.connections[connection_name] = b.Connection(self.neuron_groups[connection_name[0:2]], \
                       self.neuron_groups[connection_name[2:4]], structure='sparse', state='g' + connection_type[0])
                    # instantiate the created connection
                    if self.connectivity == 'all':
                        for feature in xrange(self.conv_features):
                            for other_feature in xrange(self.conv_features):
                                if feature != other_feature:
                                    for this_n in xrange(
                                            self.n_excitatory_patch):
                                        for other_n in xrange(
                                                self.n_excitatory_patch):
                                            if is_lattice_connection(
                                                    self.
                                                    n_excitatory_patch_sqrt,
                                                    this_n, other_n):
                                                self.connections[connection_name][feature * self.n_excitatory_patch + this_n, \
                                                  other_feature * self.n_excitatory_patch + other_n] = \
                                                    (b.random() + 0.01) * 0.3

                    elif self.connectivity == 'pairs':
                        for feature in xrange(self.conv_features):
                            if feature % 2 == 0:
                                for this_n in xrange(self.n_excitatory_patch):
                                    for other_n in xrange(
                                            self.n_excitatory_patch):
                                        if is_lattice_connection(
                                                self.n_excitatory_patch_sqrt,
                                                this_n, other_n):
                                            self.connections[connection_name][feature * self.n_excitatory_patch + this_n, \
                                              (feature + 1) * self.n_excitatory_patch + other_n] = (b.random() + 0.01) * 0.3
                            elif feature % 2 == 1:
                                for this_n in xrange(self.n_excitatory_patch):
                                    for other_n in xrange(
                                            self.n_excitatory_patch):
                                        if is_lattice_connection(
                                                self.n_excitatory_patch_patch,
                                                this_n, other_n):
                                            self.connections[connection_name][feature * self.n_excitatory_patch + this_n, \
                                              (feature - 1) * self.n_excitatory_patch + other_n] = (b.random() + 0.01) * 0.3

                    elif connectivity == 'linear':
                        for feature in xrange(self.conv_features):
                            if feature != self.conv_features - 1:
                                for this_n in xrange(self.n_excitatory_patch):
                                    for other_n in xrange(
                                            self.n_excitatory_patch):
                                        if is_lattice_connection(
                                                self.n_excitatory_patch_sqrt,
                                                this_n, other_n):
                                            self.connections[connection_name][feature * self.n_excitatory_patch + this_n, \
                                              (feature + 1) * self.n_excitatory_patch + other_n] = \
                                                 (b.random() + 0.01) * 0.3
                            if feature != 0:
                                for this_n in xrange(self.n_excitatory_patch):
                                    for other_n in xrange(
                                            self.n_excitatory_patch):
                                        if is_lattice_connection(
                                                self.n_excitatory_patch_sqrt,
                                                this_n, other_n):
                                            self.connections[connection_name][feature * self.n_excitatory_patch + this_n, \
                                              (feature - 1) * self.n_excitatory_patch + other_n] = \
                                                 (b.random() + 0.01) * 0.3

                    elif self.connectivity == 'none':
                        pass

            # if STDP from excitatory -> excitatory is on and this connection is excitatory -> excitatory
            if 'ee' in self.recurrent_conn_names:
                self.stdp_methods[name + 'e' + name + 'e'] = b.STDP(self.connections[name + 'e' + name + 'e'], \
                            eqs=eqs_stdp_ee, pre=eqs_stdp_pre_ee, \
                            post=eqs_stdp_post_ee, wmin=0., wmax=self.wmax_ee)

            print '...creating monitors for:', name

            # spike rate monitors for excitatory and inhibitory neuron populations
            self.rate_monitors[name + 'e'] = b.PopulationRateMonitor(self.neuron_groups[name + 'e'], \
                      bin=(self.single_example_time + self.resting_time) / b.second)
            self.rate_monitors[name + 'i'] = b.PopulationRateMonitor(self.neuron_groups[name + 'i'], \
                      bin=(self.single_example_time + self.resting_time) / b.second)
            self.spike_counters[name + 'e'] = b.SpikeCounter(
                self.neuron_groups[name + 'e'])

            # record neuron population spikes
            self.spike_monitors[name + 'e'] = b.SpikeMonitor(
                self.neuron_groups[name + 'e'])
            self.spike_monitors[name + 'i'] = b.SpikeMonitor(
                self.neuron_groups[name + 'i'])

        if do_plot:
            b.figure(self.fig_num)
            fig_num += 1
            b.ion()
            b.subplot(211)
            b.raster_plot(self.spike_monitors['Ae'],
                          refresh=1000 * b.ms,
                          showlast=1000 * b.ms)
            b.subplot(212)
            b.raster_plot(self.spike_monitors['Ai'],
                          refresh=1000 * b.ms,
                          showlast=1000 * b.ms)

        # specifying locations of lattice connections
        self.lattice_locations = {}
        if self.connectivity == 'all':
            for this_n in xrange(self.conv_features * self.n_excitatory_patch):
                self.lattice_locations[this_n] = [ other_n for other_n in xrange(self.conv_features * self.n_excitatory_patch) \
                        if is_lattice_connection(self.n_excitatory_patch_sqrt, \
                        this_n % self.n_excitatory_patch, other_n % self.n_excitatory_patch) ]
        elif self.connectivity == 'pairs':
            for this_n in xrange(self.conv_features * self.n_excitatory_patch):
                self.lattice_locations[this_n] = []
                for other_n in xrange(self.conv_features *
                                      self.n_excitatory_patch):
                    if this_n // self.n_excitatory_patch % 2 == 0:
                        if is_lattice_connection(self.n_excitatory_patch_sqrt, this_n % self.n_excitatory_patch, \
                               other_n % self.n_excitatory_patch) and \
                               other_n // self.n_excitatory_patch == this_n // self.n_excitatory_patch + 1:
                            self.lattice_locations[this_n].append(other_n)
                    elif this_n // self.n_excitatory_patch % 2 == 1:
                        if is_lattice_connection(self.n_excitatory_patch_sqrt, this_n % self.n_excitatory_patch, \
                               other_n % self.n_excitatory_patch) and \
                               other_n // self.n_excitatory_patch == this_n // self.n_excitatory_patch - 1:
                            self.lattice_locations[this_n].append(other_n)
        elif self.connectivity == 'linear':
            for this_n in xrange(self.conv_features * self.n_excitatory_patch):
                self.lattice_locations[this_n] = []
                for other_n in xrange(conv_features * self.n_excitatory_patch):
                    if this_n // self.n_excitatory_patch != self.conv_features - 1:
                        if is_lattice_connection(self.n_excitatory_patch_sqrt, this_n % self.n_excitatory_patch, \
                               other_n % self.n_excitatory_patch) and \
                               other_n // self.n_excitatory_patch == this_n // self.n_excitatory_patch + 1:
                            self.lattice_locations[this_n].append(other_n)
                    elif this_n // self.n_excitatory_patch != 0:
                        if is_lattice_connection(self.n_excitatory_patch_sqrt, this_n % self.n_excitatory_patch, \
                               other_n % self.n_excitatory_patch) and \
                               other_n // self.n_excitatory_patch == this_n // self.n_excitatory_patch - 1:
                            self.lattice_locations[this_n].append(other_n)

        # setting up parameters for weight normalization between patches
        num_lattice_connections = sum(
            [len(value) for value in lattice_locations.values()])
        self.weight['ee_recurr'] = (num_lattice_connections /
                                    self.conv_features) * 0.15

        # creating Poission spike train from input image (784 vector, 28x28 image)
        for name in self.input_population_names:
            self.input_groups[name + 'e'] = b.PoissonGroup(self.n_input, 0)
            self.rate_monitors[name + 'e'] = b.PopulationRateMonitor(self.input_groups[name + 'e'], \
                       bin=(self.single_example_time + self.resting_time) / b.second)

        # creating connections from input Poisson spike train to convolution patch populations
        for name in self.input_connection_names:
            print '\n...creating connections between', name[0], 'and', name[1]

            # for each of the input connection types (in this case, excitatory -> excitatory)
            for connection_type in self.input_conn_names:
                # saved connection name
                connection_name = name[0] + connection_type[0] + name[
                    1] + connection_type[1]

                # create connections from the windows of the input group to the neuron population
                self.input_connections[connection_name] = b.Connection(self.input_groups['Xe'], \
                    self.neuron_groups[name[1] + connection_type[1]], structure='sparse', \
                    state='g' + connection_type[0], delay=True, max_delay=self.delay[connection_type][1])

                for feature in xrange(self.conv_features):
                    for n in xrange(self.n_excitatory_patch):
                        for idx in xrange(self.conv_size**2):
                            self.input_connections[connection_name][self.convolution_locations[n][idx], \
                                 feature * self.n_excitatory_patch + n] = (b.random() + 0.01) * 0.3

            # if excitatory -> excitatory STDP is specified, add it here (input to excitatory populations)
            print '...creating STDP for connection', name

            # STDP connection name
            connection_name = name[0] + connection_type[0] + name[
                1] + connection_type[1]
            # create the STDP object
            self.stdp_methods[connection_name] = b.STDP(self.input_connections[connection_name], \
              eqs=eqs_stdp_ee, pre=eqs_stdp_pre_ee, post=eqs_stdp_post_ee, wmin=0., wmax=self.wmax_ee)

        print '\n'
Exemplo n.º 7
0
def fft_std(delta_u, run_num, new_connectivity, osc, rep):
    #bn.seed(int(time.time()))
    bn.reinit_default_clock()
    #bn.seed(1412958308+2)
    bn.defaultclock.dt = 0.5 * bn.ms

    #==============================================================================
    # Define constants for the model.
    #==============================================================================
    fft_file = './std_fft_p20_'
    rate_file = './std_rate_p20_'
    print delta_u
    print run_num
    print new_connectivity
    print rep

    if osc:
        T = 5.5 * bn.second
    else:
        T = 2.5 * bn.second
    n_tsteps = T / bn.defaultclock.dt
    fft_start = 0.5 * bn.second / bn.defaultclock.dt  # Time window for the FFT computation
    ro = 1.2 * bn.Hz

    SEE1 = 1.0
    SEE2 = 1.0
    qee1 = 1.00  # Fraction of NMDA receptors for e to e connections
    qee2 = 0.00
    qie1 = 1.00  # Fraction of NMDA receptors for e to i connections
    qie2 = 0.00

    uee1 = 0.2 - delta_u
    uee2 = 0.2 + delta_u
    uie1 = 0.2
    uie2 = 0.2
    trec1 = 1000.0 * bn.ms
    trec2 = 1000.0 * bn.ms

    k = 0.65
    #Jeo_const = 1.0#*bn.mV # Base strength of o (external) to e connections

    Ne = 3200  # number of excitatory neurons
    Ni = 800  # number of inhibitory neurons
    No = 20000  # number of external neurons
    N = Ne + Ni

    pcon = 0.2  # probability of connection

    Jee = 10.0 / (Ne * pcon)
    Jie = 10.0 / (Ne * pcon)
    Jii = k * 10.0 / (Ni * pcon)
    Jei = k * 10.0 / (Ni * pcon)
    Jeo = 1.0

    El = -60.0 * bn.mV  # leak reversal potential
    Vreset = -52.0 * bn.mV  # reversal potential
    Vthresh = -40.0 * bn.mV  # spiking threshold

    tref = 2.0 * bn.ms  # refractory period
    te = 20.0 * bn.ms  # membrane time constant of excitatory neurons
    ti = 10.0 * bn.ms  # membrane time constant of inhibitory neruons
    tee_ampa = 10.0 * bn.ms  # time const of ampa currents at excitatory neurons
    tee_nmda = 100.0 * bn.ms  # time const of nmda currents at excitatory neurons
    tie_ampa = 10.0 * bn.ms  # time const of ampa currents at inhibitory neurons
    tie_nmda = 100.0 * bn.ms  # time const of nmda currents at inhibitory neurons
    tii_gaba = 10.0 * bn.ms  # time const of GABA currents at inhibitory neurons
    tei_gaba = 10.0 * bn.ms  # time const of GABA currents at excitatory neurons
    teo_input = 100.0 * bn.ms

    #==============================================================================
    # Define model structure
    #==============================================================================

    model = '''
  dV/dt = (-(V-El)+J_ampa1*I_ampa1+J_nmda1*I_nmda1+J_ampa2*I_ampa2+J_nmda2*I_nmda2-J_gaba*I_gaba+J_input*I_input+eta)/tm : bn.volt
  dI_ampa1/dt = -I_ampa1/t_ampa : bn.volt
  dI_nmda1/dt = -I_nmda1/t_nmda : bn.volt
  dI_ampa2/dt = -I_ampa2/t_ampa : bn.volt
  dI_nmda2/dt = -I_nmda2/t_nmda : bn.volt
  dI_gaba/dt = -I_gaba/t_gaba : bn.volt
  dI_input/dt = (-I_input+mu)/t_input : bn.volt
  dx1/dt = (1-x1)/t1_rec : 1
  dx2/dt = (1-x2)/t2_rec : 1
  u1 : 1
  t1_rec : bn.second
  u2 : 1
  t2_rec : bn.second
  mu : bn.volt
  eta : bn.volt
  J_ampa1 : 1
  J_nmda1 : 1
  J_ampa2 : 1
  J_nmda2 : 1
  J_gaba : 1
  J_input : 1
  tm : bn.second
  t_ampa : bn.second
  t_nmda : bn.second
  t_gaba : bn.second
  t_input : bn.second
  '''

    P_reset = "V=-52*bn.mV;x1+=-u1*x1;x2+=-u2*x2"

    Se_model = '''
  we_ampa1 : bn.volt
  we_nmda1 : bn.volt
  we_ampa2 : bn.volt
  we_nmda2 : bn.volt
  '''

    Se_pre = ('I_ampa1 += x1_pre*we_ampa1', 'I_nmda1 += x1_pre*we_nmda1',
              'I_ampa2 += x2_pre*we_ampa2', 'I_nmda2 += x2_pre*we_nmda2')

    Si_model = '''
  wi_gaba : bn.volt
  '''

    Si_pre = 'I_gaba += wi_gaba'

    So_model = '''
  wo_input : bn.volt
  '''

    So_pre = 'I_input += wo_input'

    #==============================================================================
    # Define populations
    #==============================================================================

    P = bn.NeuronGroup(N,
                       model,
                       threshold=Vthresh,
                       reset=P_reset,
                       refractory=tref)

    Pe = P[0:Ne]
    Pe.tm = te
    Pe.t_ampa = tee_ampa
    Pe.t_nmda = tee_nmda
    Pe.t_gaba = tei_gaba
    Pe.t_input = teo_input
    Pe.I_ampa1 = 0 * bn.mV
    Pe.I_nmda1 = 0 * bn.mV
    Pe.I_ampa2 = 0 * bn.mV
    Pe.I_nmda2 = 0 * bn.mV
    Pe.I_gaba = 0 * bn.mV
    Pe.I_input = 0 * bn.mV
    Pe.V = (np.random.rand(Pe.V.size) * 12 - 52) * bn.mV

    Pe.x1 = 1.0
    Pe.x2 = 1.0
    Pe.u1 = uee1
    Pe.u2 = uee2
    Pe.t1_rec = trec1
    Pe.t2_rec = trec2

    Pi = P[Ne:(Ne + Ni)]
    Pi.tm = ti
    Pi.t_ampa = tie_ampa
    Pi.t_nmda = tie_nmda
    Pi.t_gaba = tii_gaba
    Pi.t_input = teo_input
    Pi.I_ampa1 = 0 * bn.mV
    Pi.I_nmda1 = 0 * bn.mV
    Pi.I_ampa2 = 0 * bn.mV
    Pi.I_nmda2 = 0 * bn.mV
    Pi.I_gaba = 0 * bn.mV
    Pi.I_input = 0 * bn.mV
    Pi.V = (np.random.rand(Pi.V.size) * 12 - 52) * bn.mV

    Pi.x1 = 1.0
    Pi.x2 = 1.0
    Pi.u1 = 0.0
    Pi.u2 = 0.0
    Pi.t1_rec = 1.0
    Pi.t2_rec = 1.0

    Pe.J_ampa1 = Jee * (1 - qee1)  #*SEE1
    Pe.J_nmda1 = Jee * qee1  #*SEE1
    Pe.J_ampa2 = Jee * (1 - qee2)  #*SEE2
    Pe.J_nmda2 = Jee * qee2  #*SEE2

    Pi.J_ampa1 = Jie * (1 - qie2)  #*SEE2
    Pi.J_nmda1 = Jie * qie2  #*SEE2
    Pi.J_ampa2 = Jie * (1 - qie1)  #*SEE1
    Pi.J_nmda2 = Jie * qie1  #*SEE1

    Pe.J_gaba = Jei
    Pi.J_gaba = Jii

    Pe.J_input = Jeo
    Pi.J_input = Jeo

    #==============================================================================
    # Define inputs
    #==============================================================================

    if osc:
        Pe.mu = 12.0 * bn.mV
        holder = np.zeros((n_tsteps, ))
        t_freq = np.linspace(0, 10, n_tsteps)

        fo = 0.2  # Smallest frequency in the signal
        fe = 10.0  # Largest frequency in the signal
        F = int(fe / 0.2)
        for m in range(1, F + 1):
            holder = holder + np.cos(2 * np.pi * m * fo * t_freq - m *
                                     (m - 1) * np.pi / F)
        holder = holder / np.max(holder)
        Pe.eta = bn.TimedArray(0.0 * bn.mV * holder)  #, dt=0.5*bn.ms)

        Background_eo = bn.PoissonInput(Pe,
                                        N=1000,
                                        rate=1.05 * bn.Hz,
                                        weight=0.2 * bn.mV,
                                        state='I_input')
        Background_io = bn.PoissonInput(Pi,
                                        N=1000,
                                        rate=1.0 * bn.Hz,
                                        weight=0.2 * bn.mV,
                                        state='I_input')

        Pi.mu = 0 * bn.mV
        Pi.eta = 0 * bn.mV  #, dt=0.5*bn.ms)

        Po = bn.PoissonGroup(No, rates=0 * bn.Hz)
    else:

        Background_eo = bn.PoissonInput(Pe,
                                        N=1000,
                                        rate=1.05 * bn.Hz,
                                        weight=0.2 * bn.mV,
                                        state='I_input')
        Background_io = bn.PoissonInput(Pi,
                                        N=1000,
                                        rate=1.0 * bn.Hz,
                                        weight=0.2 * bn.mV,
                                        state='I_input')
        holder_pe = np.zeros((n_tsteps, ))
        time_steps = np.linspace(0, T / bn.second, n_tsteps)
        holder_pe[time_steps < 0.5] = 0.0 * bn.mV
        holder_pe[time_steps >= 0.5] = 6.0 * bn.mV  #25
        holder_pe[time_steps > 1.5] = 0.0 * bn.mV  #25
        Pe.mu = bn.TimedArray(holder_pe)

        def firing_function(t, ro):
            if t > 0.5 * bn.second and t < 3.5 * bn.second:
                return 0.0 * bn.Hz
            else:
                return 0.0 * bn.Hz

        Pe.eta = 0 * bn.mV  #, dt=0.5*bn.ms)
        Pi.mu = 0.0 * bn.mV
        Pi.eta = 0 * bn.mV  #, dt=0.5*bn.ms)

        Po = bn.PoissonGroup(No, rates=lambda t: firing_function(t, ro))

    #==============================================================================
    # Define synapses
    #==============================================================================

    See1 = bn.Synapses(Pe, Pe, model=Se_model, pre=Se_pre)
    See2 = bn.Synapses(Pe, Pe, model=Se_model, pre=Se_pre)
    Sie1 = bn.Synapses(Pe, Pi, model=Se_model, pre=Se_pre)
    Sie2 = bn.Synapses(Pe, Pi, model=Se_model, pre=Se_pre)

    Sei = bn.Synapses(Pi, Pe, model=Si_model, pre=Si_pre)
    Sii = bn.Synapses(Pi, Pi, model=Si_model, pre=Si_pre)

    Seo = bn.Synapses(Po, Pe, model=So_model, pre=So_pre)

    #==============================================================================
    # Define random connections
    #==============================================================================

    if new_connectivity:
        See1.connect_random(Pe, Pe, sparseness=pcon / 2.0)
        See2.connect_random(Pe, Pe, sparseness=pcon / 2.0)
        Sie1.connect_random(Pe, Pi, sparseness=pcon / 2.0)
        Sie2.connect_random(Pe, Pi, sparseness=pcon / 2.0)
        Sii.connect_random(Pi, Pi, sparseness=pcon)
        Sei.connect_random(Pi, Pe, sparseness=pcon)
        Seo.connect_random(Po, Pe, sparseness=pcon)

        print 'Saving'
        See1.save_connectivity('./See1_connections_std_saver_p20_' +
                               str(run_num))
        See2.save_connectivity('./See2_connections_std_saver_p20_' +
                               str(run_num))
        Sie1.save_connectivity('./Sie1_connections_std_saver_p20_' +
                               str(run_num))
        Sie2.save_connectivity('./Sie2_connections_std_saver_p20_' +
                               str(run_num))
        Sii.save_connectivity('./Sii_connections_std_saver_p20_' +
                              str(run_num))
        Sei.save_connectivity('./Sei_connections_std_saver_p20_' +
                              str(run_num))
        Seo.save_connectivity('./Seo_connections_std_saver_p20_' +
                              str(run_num))
    else:
        print 'Loading'
        See1.load_connectivity('./See1_connections_std_saver_p20_' +
                               str(run_num))
        See2.load_connectivity('./See2_connections_std_saver_p20_' +
                               str(run_num))
        Sie1.load_connectivity('./Sie1_connections_std_saver_p20_' +
                               str(run_num))
        Sie2.load_connectivity('./Sie2_connections_std_saver_p20_' +
                               str(run_num))
        Sii.load_connectivity('./Sii_connections_std_saver_p20_' +
                              str(run_num))
        Sei.load_connectivity('./Sei_connections_std_saver_p20_' +
                              str(run_num))
        Seo.load_connectivity('./Seo_connections_std_saver_p20_' +
                              str(run_num))

    See1.we_ampa1 = SEE1 * 1.0 * bn.mV / tee_ampa
    See1.we_nmda1 = SEE1 * 1.0 * bn.mV / tee_nmda
    See1.we_ampa2 = 0.0 * bn.mV / tee_ampa
    See1.we_nmda2 = 0.0 * bn.mV / tee_nmda

    See2.we_ampa1 = 0.0 * bn.mV / tee_ampa
    See2.we_nmda1 = 0.0 * bn.mV / tee_nmda
    See2.we_ampa2 = SEE2 * 1.0 * bn.mV / tee_ampa
    See2.we_nmda2 = SEE2 * 1.0 * bn.mV / tee_nmda

    Sie1.we_ampa1 = 0.0 * bn.mV / tie_ampa
    Sie1.we_nmda1 = 0.0 * bn.mV / tie_nmda
    Sie1.we_ampa2 = SEE1 * 1.0 * bn.mV / tie_ampa
    Sie1.we_nmda2 = SEE1 * 1.0 * bn.mV / tie_nmda

    Sie2.we_ampa1 = SEE2 * 1.0 * bn.mV / tie_ampa
    Sie2.we_nmda1 = SEE2 * 1.0 * bn.mV / tie_nmda
    Sie2.we_ampa2 = 0.0 * bn.mV / tie_ampa
    Sie2.we_nmda2 = 0.0 * bn.mV / tie_nmda

    Sei.wi_gaba = 1.0 * bn.mV / tei_gaba
    Sii.wi_gaba = 1.0 * bn.mV / tii_gaba

    Seo.wo_input = 1.0 * bn.mV / teo_input

    #==============================================================================
    #  Define monitors
    #==============================================================================

    Pe_mon_V = bn.StateMonitor(Pe, 'V', timestep=10, record=True)
    Pe_mon_eta = bn.StateMonitor(Pe, 'eta', timestep=1, record=True)
    Pe_mon_ampa1 = bn.StateMonitor(Pe, 'I_ampa1', timestep=1, record=True)
    Pe_mon_nmda1 = bn.StateMonitor(Pe, 'I_nmda1', timestep=1, record=True)
    Pe_mon_ampa2 = bn.StateMonitor(Pe, 'I_ampa2', timestep=1, record=True)
    Pe_mon_nmda2 = bn.StateMonitor(Pe, 'I_nmda2', timestep=1, record=True)
    Pe_mon_gaba = bn.StateMonitor(Pe, 'I_gaba', timestep=1, record=True)
    Pe_mon_input = bn.StateMonitor(Pe, 'I_input', timestep=10, record=True)
    See1_mon_x = bn.StateMonitor(Pe, 'x1', timestep=10, record=True)
    See2_mon_x = bn.StateMonitor(Pe, 'x2', timestep=10, record=True)

    Pe_ratemon = bn.PopulationRateMonitor(Pe, bin=10.0 * bn.ms)
    Pi_ratemon = bn.PopulationRateMonitor(Pi, bin=10.0 * bn.ms)

    #==============================================================================
    # Run model
    #==============================================================================
    timer = 0 * bn.second
    t_start = time.time()
    bn.run(T, report='graphical')
    timer = timer + T
    print '-------------------------------------------------------'
    print 'Time is ' + str(timer) + ' seconds'
    t_end = time.time()
    print 'Time to compute last ' +str(T)+' seconds is: ' + \
          str(t_end - t_start) + ' seconds'
    print '-------------------------------------------------------\n'

    Pe_mon_ampa1_vals = Pe.J_ampa1[0] * np.mean(Pe_mon_ampa1.values.T, axis=1)
    Pe_mon_nmda1_vals = Pe.J_nmda1[0] * np.mean(Pe_mon_nmda1.values.T, axis=1)
    Pe_mon_ampa2_vals = Pe.J_ampa2[0] * np.mean(Pe_mon_ampa2.values.T, axis=1)
    Pe_mon_nmda2_vals = Pe.J_nmda2[0] * np.mean(Pe_mon_nmda2.values.T, axis=1)
    Pe_mon_ampa_vals = Pe_mon_ampa1_vals + Pe_mon_ampa2_vals
    Pe_mon_nmda_vals = Pe_mon_nmda1_vals + Pe_mon_nmda2_vals

    Pe_mon_gaba_vals = Pe.J_gaba[0] * np.mean(Pe_mon_gaba.values.T, axis=1)
    Pe_mon_input_vals = Pe.J_input[0] * np.mean(Pe_mon_input.values.T, axis=1)
    Pe_mon_V_vals = np.mean(Pe_mon_V.values.T, axis=1)

    Pe_mon_all_vals = Pe_mon_ampa_vals + Pe_mon_nmda_vals - Pe_mon_gaba_vals

    See1_mon_x_vals = np.mean(See1_mon_x.values.T, axis=1)
    See2_mon_x_vals = np.mean(See2_mon_x.values.T, axis=1)

    #==============================================================================
    # Save into a Matlab file
    #==============================================================================

    if osc:

        Pe_output = Pe.J_ampa1[0]*Pe_mon_ampa1.values+Pe.J_nmda1[0]*Pe_mon_nmda1.values + \
        Pe.J_ampa2[0]*Pe_mon_ampa2.values+Pe.J_nmda2[0]*Pe_mon_nmda2.values-Pe.J_gaba[0]*Pe_mon_gaba.values
        Pe_output = Pe_output[:, fft_start:, ]
        Pe_V = Pe_mon_V.values[:, fft_start:, ]
        Pe_glut = Pe.J_ampa1[0]*Pe_mon_ampa1.values+Pe.J_nmda1[0]*Pe_mon_nmda1.values + \
        Pe.J_ampa2[0]*Pe_mon_ampa2.values+Pe.J_nmda2[0]*Pe_mon_nmda2.values
        Pe_glut = Pe_glut[:, fft_start:, ]
        Pe_gaba = Pe.J_gaba[0] * Pe_mon_gaba.values
        Pe_gaba = Pe_gaba[:, fft_start:, ]

        Pe_input = Pe_mon_eta[:, fft_start:, ]
        T_step = bn.defaultclock.dt

        holder = {
            'Pe_output': Pe_output,
            'Pe_input': Pe_input,
            'Pe_V': Pe_V,
            'Pe_glut': Pe_glut,
            'Pe_gaba': Pe_gaba,
            'T_step': T_step
        }
        scipy.io.savemat(fft_file + 'delta_u' + str(delta_u) + '_' + str(rep),
                         mdict=holder)
    else:
        holder = {
            'Pe_rate': Pe_ratemon.rate,
            'Pe_time': Pe_ratemon.times,
            'uee1': uee1,
            'uee2': uee2,
            'uie1': uie1,
            'uie2': uie2
        }
        scipy.io.savemat(rate_file + 'delta_q_' + str(delta_u) + '_' +
                         str(run_num) + 'rep' + str(rep),
                         mdict=holder)
    bn.clear(erase=True, all=True)
def fft_nostd(qee, run_num, new_connectivity, osc, rep):

    #bn.seed(int(time.time()))
    #  bn.seed(1412958308+2)
    bn.reinit_default_clock()
    bn.defaultclock.dt = 0.5 * bn.ms

    #==============================================================================
    # Define constants for the model.
    #==============================================================================
    fft_file = './nostd_fft_p20_'
    rate_file = './nostd_rate_p20_'

    if osc:
        T = 8.0 * bn.second
    else:
        T = 3.5 * bn.second
    n_tsteps = T / bn.defaultclock.dt
    fft_start = 3.0 * bn.second / bn.defaultclock.dt  # Time window for the FFT computation
    #run_num = 10
    ro = 1.2 * bn.Hz
    #==============================================================================
    #   Need to do all others besides 0.2 and 0.5
    #==============================================================================
    print qee
    print run_num
    print new_connectivity
    print rep
    qie = 0.3  # Fraction of NMDA receptors for e to i connections

    k = 0.65
    Jeo_const = 1.0  #*bn.mV # Base strength of o (external) to e connections

    Ne = 3200  # number of excitatory neurons
    Ni = 800  # number of inhibitory neurons
    No = 2000  # number of external neurons
    N = Ne + Ni

    pcon = 0.2  # probability of connection

    Jee = 5.0 / (Ne * pcon)
    Jie = 5.0 / (Ne * pcon)
    Jii = k * 5.0 / (Ni * pcon)
    Jei = k * 5.0 / (Ni * pcon)
    Jeo = 1.0

    El = -60.0 * bn.mV  # leak reversal potential
    Vreset = -52.0 * bn.mV  # reversal potential
    Vthresh = -40.0 * bn.mV  # spiking threshold

    tref = 2.0 * bn.ms  # refractory period
    te = 20.0 * bn.ms  # membrane time constant of excitatory neurons
    ti = 10.0 * bn.ms  # membrane time constant of inhibitory neruons
    tee_ampa = 10.0 * bn.ms  # time const of ampa currents at excitatory neurons
    tee_nmda = 100.0 * bn.ms  # time const of nmda currents at excitatory neurons
    tie_ampa = 10.0 * bn.ms  # time const of ampa currents at inhibitory neurons
    tie_nmda = 100.0 * bn.ms  # time const of nmda currents at inhibitory neurons
    tii_gaba = 10.0 * bn.ms  # time const of GABA currents at inhibitory neurons
    tei_gaba = 10.0 * bn.ms  # time const of GABA currents at excitatory neurons
    teo_input = 100.0 * bn.ms

    #==============================================================================
    # Define model structure
    #==============================================================================

    model = '''
  dV/dt = (-(V-El)+J_ampa*I_ampa+J_nmda*I_nmda-J_gaba*I_gaba+J_input*I_input+eta+eta_corr)/tm : bn.volt
  dI_ampa/dt = -I_ampa/t_ampa : bn.volt
  dI_nmda/dt = -I_nmda/t_nmda : bn.volt
  dI_gaba/dt = -I_gaba/t_gaba : bn.volt
  dI_input/dt = (-I_input+mu)/t_input : bn.volt
  J_ampa : 1
  J_nmda : 1
  J_gaba : 1
  J_input : 1
  mu : bn.volt
  eta : bn.volt
  eta_corr : bn.volt
  tm : bn.second
  t_ampa : bn.second
  t_nmda : bn.second
  t_gaba : bn.second
  t_input : bn.second
  '''

    P_reset = "V=-52*bn.mV"

    Se_model = '''
  we_ampa : bn.volt
  we_nmda : bn.volt
  '''

    Se_pre = ('I_ampa += we_ampa', 'I_nmda += we_nmda')

    Si_model = '''
  wi_gaba : bn.volt
  '''

    Si_pre = 'I_gaba += wi_gaba'

    So_model = '''
  wo_input : bn.volt
  '''

    So_pre = 'I_input += wo_input'

    #==============================================================================
    # Define populations
    #==============================================================================

    P = bn.NeuronGroup(N,
                       model,
                       threshold=Vthresh,
                       reset=P_reset,
                       refractory=tref)

    Pe = P[0:Ne]
    Pe.tm = te
    Pe.t_ampa = tee_ampa
    Pe.t_nmda = tee_nmda
    Pe.t_gaba = tei_gaba
    Pe.t_input = teo_input
    Pe.I_ampa = 0 * bn.mV
    Pe.I_nmda = 0 * bn.mV
    Pe.I_gaba = 0 * bn.mV
    Pe.I_input = 0 * bn.mV
    Pe.V = (np.random.rand(Pe.V.size) * 12 - 52) * bn.mV

    Pi = P[Ne:(Ne + Ni)]
    Pi.tm = ti
    Pi.t_ampa = tie_ampa
    Pi.t_nmda = tie_nmda
    Pi.t_gaba = tii_gaba
    Pi.t_input = teo_input
    Pi.I_ampa = 0 * bn.mV
    Pi.I_nmda = 0 * bn.mV
    Pi.I_gaba = 0 * bn.mV
    Pi.I_input = 0 * bn.mV
    Pi.V = (np.random.rand(Pi.V.size) * 12 - 52) * bn.mV

    Pe.J_ampa = Jee * (1 - qee)  #*SEE1
    Pe.J_nmda = Jee * qee  #*SEE1

    Pi.J_ampa = Jie * (1 - qie)  #*SEE1
    Pi.J_nmda = Jie * qie  #*SEE1

    Pe.J_gaba = Jei
    Pi.J_gaba = Jii

    Pe.J_input = Jeo
    Pi.J_input = Jeo

    #==============================================================================
    # Define inputs
    #==============================================================================
    if osc:
        Pe.mu = 2.0 * bn.mV
        holder = np.zeros((n_tsteps, ))
        t_freq = np.linspace(0, 10, n_tsteps)

        fo = 0.2  # Smallest frequency in the signal
        fe = 10.0  # Largest frequency in the signal
        F = int(fe / 0.2)
        for m in range(1, F + 1):
            holder = holder + np.cos(2 * np.pi * m * fo * t_freq - m *
                                     (m - 1) * np.pi / F)
        holder = holder / np.max(holder)
        Pe.eta = bn.TimedArray(0.0 * bn.mV * holder)  #, dt=0.5*bn.ms)
        Pe.eta_corr = 0 * bn.mV

        Background_eo = bn.PoissonInput(Pe,
                                        N=1000,
                                        rate=1.0 * bn.Hz,
                                        weight=0.2 * bn.mV,
                                        state='I_input')
        Background_io = bn.PoissonInput(Pi,
                                        N=1000,
                                        rate=1.05 * bn.Hz,
                                        weight=0.2 * bn.mV,
                                        state='I_input')

        Pi.mu = 0 * bn.mV
        Pi.eta = 0 * bn.mV  #, dt=0.5*bn.ms)
        Pi.eta_corr = 0 * bn.mV

        Po = bn.PoissonGroup(No, rates=0 * bn.Hz)

    else:
        Background_eo = bn.PoissonInput(Pe,
                                        N=1000,
                                        rate=1.0 * bn.Hz,
                                        weight=0.2 * bn.mV,
                                        state='I_input')
        Background_io = bn.PoissonInput(Pi,
                                        N=1000,
                                        rate=1.05 * bn.Hz,
                                        weight=0.2 * bn.mV,
                                        state='I_input')

        holder_pe = np.zeros((n_tsteps, ))
        time_steps = np.linspace(0, T / bn.second, n_tsteps)
        holder_pe[time_steps < 0.5] = 0.0 * bn.mV
        holder_pe[time_steps >= 0.5] = 3.0 * bn.mV  # 35.0/Jeo *bn.mV #25
        Pe.mu = bn.TimedArray(holder_pe)

        def firing_function(t, ro):
            if t > 0.5 * bn.second and t < 3.5 * bn.second:
                return 0.0 * bn.Hz
            else:
                return 0.0 * bn.Hz

#    Pe.mu = 0*bn.mV

        Pe.eta = 0 * bn.mV  #, dt=0.5*bn.ms)
        Pi.mu = 0.0 * bn.mV
        Pi.eta = 0 * bn.mV  #, dt=0.5*bn.ms)

        Po = bn.PoissonGroup(No, rates=lambda t: firing_function(t, ro))

#==============================================================================
# Define synapses
#==============================================================================

    See = bn.Synapses(Pe, Pe, model=Se_model, pre=Se_pre)
    Sie = bn.Synapses(Pe, Pi, model=Se_model, pre=Se_pre)

    Sei = bn.Synapses(Pi, Pe, model=Si_model, pre=Si_pre)
    Sii = bn.Synapses(Pi, Pi, model=Si_model, pre=Si_pre)

    Seo = bn.Synapses(Po, Pe, model=So_model, pre=So_pre)

    #==============================================================================
    #  Define monitors
    #==============================================================================

    Pe_mon_V = bn.StateMonitor(Pe, 'V', timestep=1, record=True)
    Pe_mon_eta = bn.StateMonitor(Pe, 'eta', timestep=1, record=True)
    Pe_mon_ampa = bn.StateMonitor(Pe, 'I_ampa', timestep=1, record=True)
    Pe_mon_nmda = bn.StateMonitor(Pe, 'I_nmda', timestep=1, record=True)
    Pe_mon_gaba = bn.StateMonitor(Pe, 'I_gaba', timestep=1, record=True)
    Pe_ratemon = bn.PopulationRateMonitor(Pe, bin=10.0 * bn.ms)

    #==============================================================================
    # Define random connections
    #==============================================================================

    if new_connectivity:
        See.connect_random(Pe, Pe, sparseness=pcon)
        Sie.connect_random(Pe, Pi, sparseness=pcon)
        Sii.connect_random(Pi, Pi, sparseness=pcon)
        Sei.connect_random(Pi, Pe, sparseness=pcon)
        Seo.connect_random(Po, Pe, sparseness=pcon)

        print 'Saving'
        See.save_connectivity('./See_connections_nostd_saver_p20' +
                              str(run_num))
        Sie.save_connectivity('./Sie_connections_nostd_saver_p20' +
                              str(run_num))
        Sii.save_connectivity('./Sii_connections_nostd_saver_p20' +
                              str(run_num))
        Sei.save_connectivity('./Sei_connections_nostd_saver_p20' +
                              str(run_num))
        Seo.save_connectivity('./Seo_connections_nostd_saver_p20' +
                              str(run_num))

    else:
        print 'Loading'
        See.load_connectivity('./See_connections_nostd_saver_p20' +
                              str(run_num))
        Sie.load_connectivity('./Sie_connections_nostd_saver_p20' +
                              str(run_num))
        Sii.load_connectivity('./Sii_connections_nostd_saver_p20' +
                              str(run_num))
        Sei.load_connectivity('./Sei_connections_nostd_saver_p20' +
                              str(run_num))
        Seo.load_connectivity('./Seo_connections_nostd_saver_p20' +
                              str(run_num))

    See.we_ampa = 1.0 * bn.mV / tee_ampa
    See.we_nmda = 1.0 * bn.mV / tee_nmda

    Sie.we_ampa = 1.0 * bn.mV / tie_ampa
    Sie.we_nmda = 1.0 * bn.mV / tie_nmda

    Sei.wi_gaba = 1.0 * bn.mV / tei_gaba
    Sii.wi_gaba = 1.0 * bn.mV / tii_gaba

    Seo.wo_input = 1.0 * bn.mV / teo_input

    #==============================================================================
    # Run model
    #==============================================================================

    timer = 0 * bn.second
    t_start = time.time()
    bn.run(T, report='graphical')
    timer = timer + T
    print '-------------------------------------------------------'
    print 'Time is ' + str(timer) + ' seconds'
    t_end = time.time()
    print 'Time to compute last ' +str(T)+' seconds is: ' + \
          str(t_end - t_start) + ' seconds'
    print '-------------------------------------------------------\n'

    #==============================================================================
    # Save into a Matlab file
    #==============================================================================

    if osc:
        Pe_output = Pe.J_ampa[0] * Pe_mon_ampa.values + Pe.J_nmda[
            0] * Pe_mon_nmda.values - Pe.J_gaba[0] * Pe_mon_gaba.values
        Pe_output = Pe_output[:, fft_start:, ]
        Pe_glut = Pe.J_ampa[0] * Pe_mon_ampa.values + Pe.J_nmda[
            0] * Pe_mon_nmda.values
        Pe_glut = Pe_glut[:, fft_start:, ]
        Pe_gaba = Pe.J_gaba[0] * Pe_mon_gaba.values[:, fft_start:, ]

        Pe_V = Pe_mon_V.values[:, fft_start:, ]
        Pe_input = Pe_mon_eta[:, fft_start:, ]
        T_step = bn.defaultclock.dt

        holder = {
            'Pe_output': Pe_output,
            'Pe_input': Pe_input,
            'Pe_V': Pe_V,
            'Pe_glut': Pe_glut,
            'Pe_gaba': Pe_gaba,
            'T_step': T_step
        }
        scipy.io.savemat(fft_file + 'qee' + str(qee) + '_' + str(rep),
                         mdict=holder)

    else:
        holder = {'Pe_rate': Pe_ratemon.rate, 'Pe_time': Pe_ratemon.times}
        scipy.io.savemat(rate_file + 'qee_' + str(qee) + '_' + str(run_num) +
                         'rep' + str(rep),
                         mdict=holder)
def build_network():
    global fig_num

    neuron_groups['e'] = b.NeuronGroup(n_e_total,
                                       neuron_eqs_e,
                                       threshold=v_thresh_e,
                                       refractory=refrac_e,
                                       reset=scr_e,
                                       compile=True,
                                       freeze=True)
    neuron_groups['i'] = b.NeuronGroup(n_e_total,
                                       neuron_eqs_i,
                                       threshold=v_thresh_i,
                                       refractory=refrac_i,
                                       reset=v_reset_i,
                                       compile=True,
                                       freeze=True)

    for name in ['A']:
        print '...Creating neuron group:', name

        # get a subgroup of size 'n_e' from all exc
        neuron_groups[name + 'e'] = neuron_groups['e'].subgroup(conv_features *
                                                                n_e)
        # get a subgroup of size 'n_i' from the inhibitory layer
        neuron_groups[name + 'i'] = neuron_groups['i'].subgroup(conv_features *
                                                                n_e)

        # start the membrane potentials of these groups 40mV below their resting potentials
        neuron_groups[name + 'e'].v = v_rest_e - 40. * b.mV
        neuron_groups[name + 'i'].v = v_rest_i - 40. * b.mV

    print '...Creating recurrent connections'

    for name in ['A']:
        neuron_groups['e'].theta = np.load(
            os.path.join(best_weights_dir,
                         '_'.join(['theta_A', ending + '_best.npy'])))

        for conn_type in ['ei', 'ie']:
            if conn_type == 'ei':
                # create connection name (composed of population and connection types)
                conn_name = name + conn_type[0] + name + conn_type[1]
                # create a connection from the first group in conn_name with the second group
                connections[conn_name] = b.Connection(neuron_groups[conn_name[0:2]], \
                    neuron_groups[conn_name[2:4]], structure='sparse', state='g' + conn_type[0])
                # instantiate the created connection
                for feature in xrange(conv_features):
                    for n in xrange(n_e):
                        connections[conn_name][feature * n_e + n,
                                               feature * n_e + n] = 10.4

            elif conn_type == 'ie' and not remove_inhibition:
                # create connection name (composed of population and connection types)
                conn_name = name + conn_type[0] + name + conn_type[1]
                # create a connection from the first group in conn_name with the second group
                connections[conn_name] = b.Connection(neuron_groups[conn_name[0:2]], \
                    neuron_groups[conn_name[2:4]], structure='sparse', state='g' + conn_type[0])
                # define the actual synaptic connections and strengths
                for feature in xrange(conv_features):
                    if inhib_scheme in ['far', 'strengthen']:
                        for other_feature in set(range(conv_features)) - set(
                                neighbor_mapping[feature]):
                            if inhib_scheme == 'far':
                                for n in xrange(n_e):
                                    connections[conn_name][feature * n_e + n,
                                                           other_feature *
                                                           n_e + n] = 17.4

                            elif inhib_scheme == 'strengthen':
                                if n_e == 1:
                                    x, y = feature // np.sqrt(
                                        n_e_total), feature % np.sqrt(
                                            n_e_total)
                                    x_, y_ = other_feature // np.sqrt(
                                        n_e_total), other_feature % np.sqrt(
                                            n_e_total)
                                else:
                                    x, y = feature // np.sqrt(
                                        conv_features), feature % np.sqrt(
                                            conv_features)
                                    x_, y_ = other_feature // np.sqrt(
                                        conv_features
                                    ), other_feature % np.sqrt(conv_features)

                                for n in xrange(n_e):
                                    connections[conn_name][feature * n_e + n, other_feature * n_e + n] = \
                                        min(17.4, inhib_const * np.sqrt(euclidean([x, y], [x_, y_])))

                    elif inhib_scheme == 'increasing':
                        for other_feature in xrange(conv_features):
                            if n_e == 1:
                                x, y = feature // np.sqrt(
                                    n_e_total), feature % np.sqrt(n_e_total)
                                x_, y_ = other_feature // np.sqrt(
                                    n_e_total), other_feature % np.sqrt(
                                        n_e_total)
                            else:
                                x, y = feature // np.sqrt(
                                    conv_features), feature % np.sqrt(
                                        conv_features)
                                x_, y_ = other_feature // np.sqrt(
                                    conv_features), other_feature % np.sqrt(
                                        conv_features)

                            if feature != other_feature:
                                for n in xrange(n_e):
                                    connections[conn_name][feature * n_e + n, other_feature * n_e + n] = \
                                        min(17.4, inhib_const * np.sqrt(euclidean([x, y], [x_, y_])))

                    else:
                        raise Exception(
                            'Expecting one of "far", "increasing", or "strengthen" for argument "inhib_scheme".'
                        )

        # spike rate monitors for excitatory and inhibitory neuron populations
        rate_monitors[name + 'e'] = b.PopulationRateMonitor(
            neuron_groups[name + 'e'],
            bin=(single_example_time + resting_time) / b.second)
        rate_monitors[name + 'i'] = b.PopulationRateMonitor(
            neuron_groups[name + 'i'],
            bin=(single_example_time + resting_time) / b.second)
        spike_counters[name + 'e'] = b.SpikeCounter(neuron_groups[name + 'e'])

        # record neuron population spikes if specified
        if record_spikes:
            spike_monitors[name + 'e'] = b.SpikeMonitor(neuron_groups[name +
                                                                      'e'])
            spike_monitors[name + 'i'] = b.SpikeMonitor(neuron_groups[name +
                                                                      'i'])

    if record_spikes and do_plot:
        if reset_state_vars:
            time_window = single_example_time * 1000
        else:
            time_window = (single_example_time + resting_time) * 1000

        b.figure(fig_num, figsize=(8, 6))
        b.ion()
        b.subplot(211)
        b.raster_plot(spike_monitors['Ae'],
                      refresh=time_window * b.ms,
                      showlast=time_window * b.ms,
                      title='Excitatory spikes per neuron')
        b.subplot(212)
        b.raster_plot(spike_monitors['Ai'],
                      refresh=time_window * b.ms,
                      showlast=time_window * b.ms,
                      title='Inhibitory spikes per neuron')
        b.tight_layout()

        fig_num += 1

    # creating Poission spike train from input image (784 vector, 28x28 image)
    for name in ['X']:
        input_groups[name + 'e'] = b.PoissonGroup(n_input, 0)
        rate_monitors[name + 'e'] = b.PopulationRateMonitor(
            input_groups[name + 'e'],
            bin=(single_example_time + resting_time) / b.second)

    # creating connections from input Poisson spike train to convolution patch populations
    for name in ['XA']:
        print '\n...Creating connections between', name[0], 'and', name[1]

        # for each of the input connection types (in this case, excitatory -> excitatory)
        for conn_type in ['ee_input']:
            # saved connection name
            conn_name = name[0] + conn_type[0] + name[1] + conn_type[1]

            # get weight matrix depending on training or test phase
            weight_matrix = np.load(
                os.path.join(best_weights_dir,
                             '_'.join([conn_name, ending + '_best.npy'])))

            # create connections from the windows of the input group to the neuron population
            input_connections[conn_name] = b.Connection(input_groups['Xe'], neuron_groups[name[1] + \
              conn_type[1]], structure='sparse', state='g' + conn_type[0], delay=True, max_delay=delay[conn_type][1])

            for feature in xrange(conv_features):
                for n in xrange(n_e):
                    for idx in xrange(conv_size**2):
                        input_connections[conn_name][convolution_locations[n][idx], feature * n_e + n] = \
                             weight_matrix[convolution_locations[n][idx], feature * n_e + n]

            if do_plot:
                plot_2d_input_weights()
                fig_num += 1