Exemplo n.º 1
0
Arquivo: sfm.py Projeto: qytian/dipy
    def __init__(self, gtab, sphere=None, response=[0.0015, 0.0005, 0.0005],
                 solver='ElasticNet', l1_ratio=0.5, alpha=0.001):
        """
        Initialize a Sparse Fascicle Model

        Parameters
        ----------
        gtab : GradientTable class instance
        sphere : Sphere class instance, optional
            A sphere on which coefficients will be estimated. Default:
        symmetric sphere with 362 points (from :mod:`dipy.data`).
        response : (3,) array-like, optional
            The eigenvalues of a canonical tensor to be used as the response
            function of single-fascicle signals.
            Default:[0.0015, 0.0005, 0.0005]

        solver : string or SKLearnLinearSolver object, optional
            This will determine the algorithm used to solve the set of linear
            equations underlying this model. If it is a string it needs to be
            one of the following: {'ElasticNet', 'NNLS'}. Otherwise, it can be
            an object that inherits from `dipy.optimize.SKLearnLinearSolver`.
            Default: 'ElasticNet'.

        l1_ratio : float, optional
            Sets the balance betwee L1 and L2 regularization in ElasticNet
            [Zou2005]_. Default: 0.5
        alpha : float, optional
            Sets the balance between least-squares error and L1/L2
            regularization in ElasticNet [Zou2005]_. Default: 0.001

        Notes
        -----
        This is an implementation of the SFM, described in [Rokem2014]_.

        .. [Rokem2014] Ariel Rokem, Jason D. Yeatman, Franco Pestilli, Kendrick
           N. Kay, Aviv Mezer, Stefan van der Walt, Brian A. Wandell
           (2014). Evaluating the accuracy of diffusion MRI models in white
           matter. http://arxiv.org/abs/1411.0721

        .. [Zou2005] Zou H, Hastie T (2005). Regularization and variable
           selection via the elastic net. J R Stat Soc B:301-320
        """
        ReconstModel.__init__(self, gtab)
        if sphere is None:
            sphere = dpd.get_sphere()
        self.sphere = sphere
        self.response = np.asarray(response)

        if solver == 'ElasticNet':
            self.solver = lm.ElasticNet(l1_ratio=l1_ratio, alpha=alpha,
                                        positive=True, warm_start=True)
        elif solver == 'NNLS' or solver == 'nnls':
            self.solver = opt.NonNegativeLeastSquares()
        elif isinstance(solver, opt.SKLearnLinearSolver):
            self.solver = solver
        else:
            e_s = "The `solver` key-word argument needs to be: "
            e_s += "'ElasticNet', 'NNLS', or a "
            e_s += "`dipy.optimize.SKLearnLinearSolver` object"
            raise ValueError(e_s)
Exemplo n.º 2
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    def __init__(self, gtab):
        """
        Initialize an IsotropicModel

        Parameters
        ----------
        gtab : a GradientTable class instance
        """
        ReconstModel.__init__(self, gtab)
Exemplo n.º 3
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    def __init__(self, gtab):
        """
        Parameters
        ----------
        gtab : a GradientTable class instance

        """
        # Initialize the super-class:
        ReconstModel.__init__(self, gtab)
Exemplo n.º 4
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    def __init__(self, gtab):
        """
        Initialize an IsotropicModel.

        Parameters
        ----------
        gtab : a GradientTable class instance
        """
        ReconstModel.__init__(self, gtab)
Exemplo n.º 5
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    def __init__(self, gtab):
        """
        Parameters
        ----------
        gtab : a GradientTable class instance

        """
        # Initialize the super-class:
        ReconstModel.__init__(self, gtab)
Exemplo n.º 6
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    def __init__(self, gtab, fit_method="NLS", *args, **kwargs):
        """ Free Water Diffusion Tensor Model [1]_.

        Parameters
        ----------
        gtab : GradientTable class instance
        fit_method : str or callable
            str can be one of the following:

            'WLS' for weighted linear least square fit according to [1]_
                :func:`fwdti.wls_iter`
            'NLS' for non-linear least square fit according to [1]_
                :func:`fwdti.nls_iter`

            callable has to have the signature:
              fit_method(design_matrix, data, *args, **kwargs)
        args, kwargs : arguments and key-word arguments passed to the
           fit_method. See fwdti.wls_iter, fwdti.nls_iter for
           details

        References
        ----------
        .. [1] Hoy, A.R., Koay, C.G., Kecskemeti, S.R., Alexander, A.L., 2014.
               Optimization of a free water elimination two-compartmental model
               for diffusion tensor imaging. NeuroImage 103, 323-333.
               doi: 10.1016/j.neuroimage.2014.09.053
        """
        ReconstModel.__init__(self, gtab)

        if not callable(fit_method):
            try:
                fit_method = common_fit_methods[fit_method]
            except KeyError:
                e_s = '"' + str(fit_method) + '" is not a known fit '
                e_s += 'method, the fit method should either be a '
                e_s += 'function or one of the common fit methods'
                raise ValueError(e_s)
        self.fit_method = fit_method
        self.design_matrix = design_matrix(self.gtab)
        self.args = args
        self.kwargs = kwargs

        # Check if at least three b-values are given
        bmag = int(np.log10(self.gtab.bvals.max()))
        b = self.gtab.bvals.copy() / (10 ** (bmag-1))  # normalize b units
        b = b.round()
        uniqueb = np.unique(b)
        if len(uniqueb) < 3:
            mes = "fwdti fit requires data for at least 2 non zero b-values"
            raise ValueError(mes)
Exemplo n.º 7
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    def __init__(self, gtab, fit_method="NLS", *args, **kwargs):
        """ Free Water Diffusion Tensor Model [1]_.

        Parameters
        ----------
        gtab : GradientTable class instance
        fit_method : str or callable
            str can be one of the following:

            'WLS' for weighted linear least square fit according to [1]_
                :func:`fwdti.wls_iter`
            'NLS' for non-linear least square fit according to [1]_
                :func:`fwdti.nls_iter`

            callable has to have the signature:
              fit_method(design_matrix, data, *args, **kwargs)
        args, kwargs : arguments and key-word arguments passed to the
           fit_method. See fwdti.wls_iter, fwdti.nls_iter for
           details

        References
        ----------
        .. [1] Hoy, A.R., Koay, C.G., Kecskemeti, S.R., Alexander, A.L., 2014.
               Optimization of a free water elimination two-compartmental model
               for diffusion tensor imaging. NeuroImage 103, 323-333.
               doi: 10.1016/j.neuroimage.2014.09.053
        """
        ReconstModel.__init__(self, gtab)

        if not callable(fit_method):
            try:
                fit_method = common_fit_methods[fit_method]
            except KeyError:
                e_s = '"' + str(fit_method) + '" is not a known fit '
                e_s += 'method, the fit method should either be a '
                e_s += 'function or one of the common fit methods'
                raise ValueError(e_s)
        self.fit_method = fit_method
        self.design_matrix = design_matrix(self.gtab)
        self.args = args
        self.kwargs = kwargs

        # Check if at least three b-values are given
        bmag = int(np.log10(self.gtab.bvals.max()))
        b = self.gtab.bvals.copy() / (10**(bmag - 1))  # normalize b units
        b = b.round()
        uniqueb = np.unique(b)
        if len(uniqueb) < 3:
            mes = "fwdti fit requires data for at least 2 non zero b-values"
            raise ValueError(mes)
Exemplo n.º 8
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    def __init__(self, gtab, fit_method="NLS", *args, **kwargs):
        """ Free Water Diffusion Tensor Model [1]_.

        Parameters
        ----------
        gtab : GradientTable class instance
        fit_method : str or callable
            str can be one of the following:

            'WLS' for weighted linear least square fit according to [1]_
                :func:`fwdti.wls_iter`
            'NLS' for non-linear least square fit according to [1]_
                :func:`fwdti.nls_iter`

            callable has to have the signature:
              fit_method(design_matrix, data, *args, **kwargs)
        args, kwargs : arguments and key-word arguments passed to the
           fit_method. See fwdti.wls_iter, fwdti.nls_iter for
           details

        References
        ----------
        .. [1] Henriques, R.N., Rokem, A., Garyfallidis, E., St-Jean, S.,
               Peterson E.T., Correia, M.M., 2017. [Re] Optimization of a free
               water elimination two-compartment model for diffusion tensor
               imaging. ReScience volume 3, issue 1, article number 2

        """
        ReconstModel.__init__(self, gtab)

        if not callable(fit_method):
            try:
                fit_method = common_fit_methods[fit_method]
            except KeyError:
                e_s = '"' + str(fit_method) + '" is not a known fit '
                e_s += 'method, the fit method should either be a '
                e_s += 'function or one of the common fit methods'
                raise ValueError(e_s)
        self.fit_method = fit_method
        self.design_matrix = design_matrix(self.gtab)
        self.args = args
        self.kwargs = kwargs

        # Check if at least three b-values are given
        enough_b = check_multi_b(self.gtab, 3, non_zero=False)
        if not enough_b:
            mes = "fwDTI requires at least 3 b-values (which can include b=0)"
            raise ValueError(mes)
Exemplo n.º 9
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    def __init__(self, gtab, fit_method="NLS", *args, **kwargs):
        """ Free Water Diffusion Tensor Model [1]_.

        Parameters
        ----------
        gtab : GradientTable class instance
        fit_method : str or callable
            str can be one of the following:

            'WLS' for weighted linear least square fit according to [1]_
                :func:`fwdti.wls_iter`
            'NLS' for non-linear least square fit according to [1]_
                :func:`fwdti.nls_iter`

            callable has to have the signature:
              fit_method(design_matrix, data, *args, **kwargs)
        args, kwargs : arguments and key-word arguments passed to the
           fit_method. See fwdti.wls_iter, fwdti.nls_iter for
           details

        References
        ----------
        .. [1] Hoy, A.R., Koay, C.G., Kecskemeti, S.R., Alexander, A.L., 2014.
               Optimization of a free water elimination two-compartmental model
               for diffusion tensor imaging. NeuroImage 103, 323-333.
               doi: 10.1016/j.neuroimage.2014.09.053
        """
        ReconstModel.__init__(self, gtab)

        if not callable(fit_method):
            try:
                fit_method = common_fit_methods[fit_method]
            except KeyError:
                e_s = '"' + str(fit_method) + '" is not a known fit '
                e_s += 'method, the fit method should either be a '
                e_s += 'function or one of the common fit methods'
                raise ValueError(e_s)
        self.fit_method = fit_method
        self.design_matrix = design_matrix(self.gtab)
        self.args = args
        self.kwargs = kwargs

        # Check if at least three b-values are given
        enough_b = check_multi_b(self.gtab, 3, non_zero=False)
        if not enough_b:
            mes = "fwDTI requires at least 3 b-values (which can include b=0)"
            raise ValueError(mes)
Exemplo n.º 10
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    def __init__(self, gtab, fit_method="NLS", *args, **kwargs):
        """ Free Water Diffusion Tensor Model [1]_.

        Parameters
        ----------
        gtab : GradientTable class instance
        fit_method : str or callable
            str can be one of the following:

            'WLS' for weighted linear least square fit according to [1]_
                :func:`fwdti.wls_iter`
            'NLS' for non-linear least square fit according to [1]_
                :func:`fwdti.nls_iter`

            callable has to have the signature:
              fit_method(design_matrix, data, *args, **kwargs)
        args, kwargs : arguments and key-word arguments passed to the
           fit_method. See fwdti.wls_iter, fwdti.nls_iter for
           details

        References
        ----------
        .. [1] Hoy, A.R., Koay, C.G., Kecskemeti, S.R., Alexander, A.L., 2014.
               Optimization of a free water elimination two-compartmental model
               for diffusion tensor imaging. NeuroImage 103, 323-333.
               doi: 10.1016/j.neuroimage.2014.09.053
        """
        ReconstModel.__init__(self, gtab)

        if not callable(fit_method):
            try:
                fit_method = common_fit_methods[fit_method]
            except KeyError:
                e_s = '"' + str(fit_method) + '" is not a known fit '
                e_s += 'method, the fit method should either be a '
                e_s += 'function or one of the common fit methods'
                raise ValueError(e_s)
        self.fit_method = fit_method
        self.design_matrix = design_matrix(self.gtab)
        self.args = args
        self.kwargs = kwargs

        # Check if at least three b-values are given
        enough_b = check_multi_b(self.gtab, 3, non_zero=False)
        if not enough_b:
            mes = "fwDTI requires at least 3 b-values (which can include b=0)"
            raise ValueError(mes)
Exemplo n.º 11
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    def __init__(self, gtab, bmag=None, return_S0_hat=False, *args, **kwargs):
        """ Mean Signal Diffusion Kurtosis Model [1]_.

        Parameters
        ----------
        gtab : GradientTable class instance

        bmag : int
            The order of magnitude that the bvalues have to differ to be
            considered an unique b-value. Default: derive this value from the
            maximal b-value provided: $bmag=log_{10}(max(bvals)) - 1$.

        return_S0_hat : bool
            If True, also return S0 values for the fit.

        args, kwargs : arguments and keyword arguments passed to the
        fit_method. See msdki.wls_fit_msdki for details

        References
        ----------
        .. [1] Henriques, R.N., 2018. Advanced Methods for Diffusion MRI Data
               Analysis and their Application to the Healthy Ageing Brain
               (Doctoral thesis). Downing College, University of Cambridge.
               https://doi.org/10.17863/CAM.29356

        """
        ReconstModel.__init__(self, gtab)

        self.return_S0_hat = return_S0_hat
        self.ubvals = unique_bvals_magnitude(gtab.bvals, bmag=bmag)
        self.design_matrix = design_matrix(self.ubvals)
        self.bmag = bmag
        self.args = args
        self.kwargs = kwargs
        self.min_signal = self.kwargs.pop('min_signal', MIN_POSITIVE_SIGNAL)
        if self.min_signal is not None and self.min_signal <= 0:
            e_s = "The `min_signal` key-word argument needs to be strictly"
            e_s += " positive."
            raise ValueError(e_s)

        # Check if at least three b-values are given
        enough_b = check_multi_b(self.gtab, 3, non_zero=False, bmag=bmag)
        if not enough_b:
            mes = "MSDKI requires at least 3 b-values (which can include b=0)"
            raise ValueError(mes)
Exemplo n.º 12
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    def __init__(self, gtab, bmag=None, return_S0_hat=False, *args, **kwargs):
        """ Mean Signal Diffusion Kurtosis Model [1]_.

        Parameters
        ----------
        gtab : GradientTable class instance

        bmag : int
            The order of magnitude that the bvalues have to differ to be
            considered an unique b-value. Default: derive this value from the
            maximal b-value provided: $bmag=log_{10}(max(bvals)) - 1$.

        return_S0_hat : bool
            If True, also return S0 values for the fit.

        args, kwargs : arguments and keyword arguments passed to the
        fit_method. See msdki.wls_fit_msdki for details

        References
        ----------
        .. [1] Henriques, R.N., 2018. Advanced Methods for Diffusion MRI Data
               Analysis and their Application to the Healthy Ageing Brain
               (Doctoral thesis). Downing College, University of Cambridge.
               https://doi.org/10.17863/CAM.29356
        """
        ReconstModel.__init__(self, gtab)

        self.return_S0_hat = return_S0_hat
        self.ubvals = unique_bvals(gtab.bvals, bmag=bmag)
        self.design_matrix = design_matrix(self.ubvals)
        self.bmag = bmag
        self.args = args
        self.kwargs = kwargs
        self.min_signal = self.kwargs.pop('min_signal', MIN_POSITIVE_SIGNAL)
        if self.min_signal is not None and self.min_signal <= 0:
            e_s = "The `min_signal` key-word argument needs to be strictly"
            e_s += " positive."
            raise ValueError(e_s)

        # Check if at least three b-values are given
        enough_b = check_multi_b(self.gtab, 3, non_zero=False, bmag=bmag)
        if not enough_b:
            mes = "MSDKI requires at least 3 b-values (which can include b=0)"
            raise ValueError(mes)
Exemplo n.º 13
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    def __init__(self, gtab, split_b_D=200.0, n_threads=1):
        """
        Model to reconstruct an IVIM tensor

        Parameters
        ----------
        gtab : GradientTable class instance

        split_b_D : float
            The value of b that separates perfusion from diffusion
        """
        ReconstModel.__init__(self, gtab)
        self.split_b_D = split_b_D
        # Use two separate tensors for initial estimation:
        self.diffusion_idx = np.hstack(
            [np.where(gtab.bvals > self.split_b_D),
             np.where(gtab.b0s_mask)]).squeeze()

        # The first tensor represents diffusion
        self.diffusion_gtab = gradient_table(
            self.gtab.bvals[self.diffusion_idx],
            self.gtab.bvecs[self.diffusion_idx])

        self.diffusion_model = TensorModel(self.diffusion_gtab)

        # The second tensor represents perfusion:
        self.perfusion_idx = np.array(
            np.where(gtab.bvals <= self.split_b_D)).squeeze()
        self.perfusion_gtab = gradient_table(
            self.gtab.bvals[self.perfusion_idx],
            self.gtab.bvecs[self.perfusion_idx])

        self.perfusion_model = TensorModel(self.perfusion_gtab)

        # We'll need a "vanilla" IVIM model:
        self.ivim_model = IvimModel(self.gtab)
        # How many threads in parallel execution:
        self.n_threads = n_threads
Exemplo n.º 14
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    def __init__(self, gtab, fit_method='WLS'):
        """Covariance tensor model of q-space trajectory imaging [1]_.

        Parameters
        ----------
        gtab : dipy.core.gradients.GradientTable
            Gradient table with b-tensors.
        fit_method : str, optional
            Must be one of the followng:
                'OLS' for ordinary least squares
                    :func:`qti._ols_fit`
                'WLS' for weighted least squares
                    :func:`qti._wls_fit`

        References
        ----------
        .. [1] Westin, Carl-Fredrik, et al. "Q-space trajectory imaging for
           multidimensional diffusion MRI of the human brain." Neuroimage 135
           (2016): 345-362. https://doi.org/10.1016/j.neuroimage.2016.02.039.
        """
        ReconstModel.__init__(self, gtab)

        if self.gtab.btens is None:
            raise ValueError(
                'QTI requires b-tensors to be defined in the gradient table.')
        self.X = design_matrix(self.gtab.btens)
        rank = np.linalg.matrix_rank(self.X.T @ self.X)
        if rank < 28:
            warn('The combination of the b-tensor shapes, sizes, and ' +
                 'orientations does not enable all elements of the covariance '
                 + 'tensor to be estimated (rank(X.T @ X) = %s < 28).' % rank)

        try:
            self.fit_method = common_fit_methods[fit_method]
        except KeyError:
            raise ValueError('Invalid value (%s) for \'fit_method\'.' %
                             fit_method + ' Options: \'OLS\', \'WLS\'.')
Exemplo n.º 15
0
Arquivo: sfm.py Projeto: MPDean/dipy
    def __init__(self, gtab, sphere=None, response=[0.0015, 0.0005, 0.0005],
                 solver='ElasticNet', l1_ratio=0.5, alpha=0.001, isotropic=None):
        """
        Initialize a Sparse Fascicle Model

        Parameters
        ----------
        gtab : GradientTable class instance
        sphere : Sphere class instance, optional
            A sphere on which coefficients will be estimated. Default:
        symmetric sphere with 362 points (from :mod:`dipy.data`).
        response : (3,) array-like, optional
            The eigenvalues of a canonical tensor to be used as the response
            function of single-fascicle signals.
            Default:[0.0015, 0.0005, 0.0005]
        solver : string, dipy.core.optimize.SKLearnLinearSolver object, or sklearn.linear_model.base.LinearModel object, optional.
            This will determine the algorithm used to solve the set of linear
            equations underlying this model. If it is a string it needs to be
            one of the following: {'ElasticNet', 'NNLS'}. Otherwise, it can be
            an object that inherits from `dipy.optimize.SKLearnLinearSolver`.
            Default: 'ElasticNet'.
        l1_ratio : float, optional
            Sets the balance betwee L1 and L2 regularization in ElasticNet
            [Zou2005]_. Default: 0.5
        alpha : float, optional
            Sets the balance between least-squares error and L1/L2
            regularization in ElasticNet [Zou2005]_. Default: 0.001
        isotropic : IsotropicModel class instance
            This is a class that implements the function that calculates the
            value of the isotropic signal. This is a value of the signal that is
            independent of direction, and therefore removed from both sides of
            the SFM equation. The default is an instance of IsotropicModel, but
            other functions can be inherited from IsotropicModel to implement
            other fits to the aspects of the data that depend on b-value, but
            not on direction.

        Notes
        -----
        This is an implementation of the SFM, described in [Rokem2015]_.

        .. [Rokem2014] Ariel Rokem, Jason D. Yeatman, Franco Pestilli, Kendrick
           N. Kay, Aviv Mezer, Stefan van der Walt, Brian A. Wandell
           (2014). Evaluating the accuracy of diffusion MRI models in white
           matter. PLoS ONE 10(4): e0123272. doi:10.1371/journal.pone.0123272

        .. [Zou2005] Zou H, Hastie T (2005). Regularization and variable
           selection via the elastic net. J R Stat Soc B:301-320
        """
        ReconstModel.__init__(self, gtab)
        if sphere is None:
            sphere = dpd.get_sphere()
        self.sphere = sphere
        self.response = np.asarray(response)
        if isotropic is None:
            isotropic = IsotropicModel

        self.isotropic = isotropic
        if solver == 'ElasticNet':
            self.solver = lm.ElasticNet(l1_ratio=l1_ratio, alpha=alpha,
                                        positive=True, warm_start=True)
        elif solver == 'NNLS' or solver == 'nnls':
            self.solver = opt.NonNegativeLeastSquares()

        elif (isinstance(solver, opt.SKLearnLinearSolver) or
            has_sklearn and isinstance(solver, lm.base.LinearModel)):
            self.solver = solver

        else:
            e_s = "The `solver` key-word argument needs to be: "
            e_s += "'ElasticNet', 'NNLS', or a "
            e_s += "`dipy.optimize.SKLearnLinearSolver` object"
            raise ValueError(e_s)
Exemplo n.º 16
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Arquivo: odf.py Projeto: MarcCote/dipy
 def __init__(self, gtab):
     ReconstModel.__init__(self, gtab)
Exemplo n.º 17
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    def __init__(self, gtab, split_b_D=400.0, split_b_S0=200., bounds=None,
                 two_stage=True, tol=1e-15,
                 x_scale=[1000., 0.1, 0.001, 0.0001],
                 gtol=1e-15, ftol=1e-15, eps=1e-15, maxiter=1000):

        r"""
        Initialize an IVIM model.

        The IVIM model assumes that biological tissue includes a volume
        fraction 'f' of water flowing with a pseudo-diffusion coefficient
        D* and a fraction (1-f) of static (diffusion only), intra and
        extracellular water, with a diffusion coefficient D. In this model
        the echo attenuation of a signal in a single voxel can be written as

            .. math::

            S(b) = S_0[f*e^{(-b*D\*)} + (1-f)e^{(-b*D)}]

            Where:
            .. math::

            S_0, f, D\* and D are the IVIM parameters.

        Parameters
        ----------
        gtab : GradientTable class instance
            Gradient directions and bvalues

        split_b_D : float, optional
            The b-value to split the data on for two-stage fit. This will be
            used while estimating the value of D. The assumption is that at
            higher b values the effects of perfusion is less and hence the
            signal can be approximated as a mono-exponential decay.
            default : 400.

        split_b_S0 : float, optional
            The b-value to split the data on for two-stage fit for estimation
            of S0 and initial guess for D_star. The assumption here is that
            at low bvalues the effects of perfusion are more.
            default : 200.

        bounds : tuple of arrays with 4 elements, optional
            Bounds to constrain the fitted model parameters. This is only
            supported for Scipy version > 0.17. When using a older Scipy
            version, this function will raise an error if bounds are different
            from None. This parameter is also used to fill nan values for out
            of bounds parameters in the `IvimFit` class using the method
            fill_na. default : ([0., 0., 0., 0.], [np.inf, .3, 1., 1.])

        two_stage : bool
            Argument to specify whether to perform a non-linear fitting of all
            parameters after the linear fitting by splitting the data based on
            bvalues. This gives more accurate parameters but takes more time.
            The linear fit can be used to get a quick estimation of the
            parameters. default : False

        tol : float, optional
            Tolerance for convergence of minimization.
            default : 1e-15

        x_scale : array, optional
            Scaling for the parameters. This is passed to `least_squares` which
            is only available for Scipy version > 0.17.
            default: [1000, 0.01, 0.001, 0.0001]

        gtol : float, optional
            Tolerance for termination by the norm of the gradient.
            default : 1e-15

        ftol : float, optional
            Tolerance for termination by the change of the cost function.
            default : 1e-15

        eps : float, optional
            Step size used for numerical approximation of the jacobian.
            default : 1e-15

        maxiter : int, optional
            Maximum number of iterations to perform.
            default : 1000

        References
        ----------
        .. [1] Le Bihan, Denis, et al. "Separation of diffusion and perfusion
               in intravoxel incoherent motion MR imaging." Radiology 168.2
               (1988): 497-505.
        .. [2] Federau, Christian, et al. "Quantitative measurement of brain
               perfusion with intravoxel incoherent motion MR imaging."
               Radiology 265.3 (2012): 874-881.
        """
        if not np.any(gtab.b0s_mask):
            e_s = "No measured signal at bvalue == 0."
            e_s += "The IVIM model requires signal measured at 0 bvalue"
            raise ValueError(e_s)

        if gtab.b0_threshold > 0:
            b0_s = "The IVIM model requires a measurement at b==0. As of "
            b0_s += "version 0.15, the default b0_threshold for the "
            b0_s += "GradientTable object is set to 50, so if you used the "
            b0_s += "default settings to initialize the gtab input to the "
            b0_s += "IVIM model, you may have provided a gtab with "
            b0_s += "b0_threshold larger than 0. Please initialize the gtab "
            b0_s += "input with b0_threshold=0"
            raise ValueError(b0_s)

        ReconstModel.__init__(self, gtab)
        self.split_b_D = split_b_D
        self.split_b_S0 = split_b_S0
        self.bounds = bounds
        self.two_stage = two_stage
        self.tol = tol
        self.options = {'gtol': gtol, 'ftol': ftol,
                        'eps': eps, 'maxiter': maxiter}
        self.x_scale = x_scale

        if SCIPY_LESS_0_17 and self.bounds is not None:
            e_s = "Scipy versions less than 0.17 do not support "
            e_s += "bounds. Please update to Scipy 0.17 to use bounds"
            raise ValueError(e_s)
        elif self.bounds is None:
            self.bounds = ((0., 0., 0., 0.), (np.inf, .3, 1., 1.))
        else:
            self.bounds = bounds
Exemplo n.º 18
0
    def __init__(self,
                 gtab,
                 sphere=None,
                 response=[0.0015, 0.0005, 0.0005],
                 solver='ElasticNet',
                 l1_ratio=0.5,
                 alpha=0.001,
                 isotropic=None):
        """
        Initialize a Sparse Fascicle Model

        Parameters
        ----------
        gtab : GradientTable class instance
        sphere : Sphere class instance, optional
            A sphere on which coefficients will be estimated. Default:
        symmetric sphere with 362 points (from :mod:`dipy.data`).
        response : (3,) array-like, optional
            The eigenvalues of a canonical tensor to be used as the response
            function of single-fascicle signals.
            Default:[0.0015, 0.0005, 0.0005]
        solver : string, or initialized linear model object.
            This will determine the algorithm used to solve the set of linear
            equations underlying this model. If it is a string it needs to be
            one of the following: {'ElasticNet', 'NNLS'}. Otherwise, it can be
            an object that inherits from `dipy.optimize.SKLearnLinearSolver`
            or an object with a similar interface from Scikit Learn:
            `sklearn.linear_model.ElasticNet`, `sklearn.linear_model.Lasso` or
            `sklearn.linear_model.Ridge` and other objects that inherit from
            `sklearn.base.RegressorMixin`.
            Default: 'ElasticNet'.

        l1_ratio : float, optional
            Sets the balance betwee L1 and L2 regularization in ElasticNet
            [Zou2005]_. Default: 0.5
        alpha : float, optional
            Sets the balance between least-squares error and L1/L2
            regularization in ElasticNet [Zou2005]_. Default: 0.001
        isotropic : IsotropicModel class instance
            This is a class that implements the function that calculates the
            value of the isotropic signal. This is a value of the signal that is
            independent of direction, and therefore removed from both sides of
            the SFM equation. The default is an instance of IsotropicModel, but
            other functions can be inherited from IsotropicModel to implement
            other fits to the aspects of the data that depend on b-value, but
            not on direction.

        Notes
        -----
        This is an implementation of the SFM, described in [Rokem2015]_.

        .. [Rokem2014] Ariel Rokem, Jason D. Yeatman, Franco Pestilli, Kendrick
           N. Kay, Aviv Mezer, Stefan van der Walt, Brian A. Wandell
           (2014). Evaluating the accuracy of diffusion MRI models in white
           matter. PLoS ONE 10(4): e0123272. doi:10.1371/journal.pone.0123272

        .. [Zou2005] Zou H, Hastie T (2005). Regularization and variable
           selection via the elastic net. J R Stat Soc B:301-320
        """
        ReconstModel.__init__(self, gtab)
        if sphere is None:
            sphere = dpd.get_sphere()
        self.sphere = sphere
        self.response = np.asarray(response)
        if isotropic is None:
            isotropic = IsotropicModel

        self.isotropic = isotropic
        if solver == 'ElasticNet':
            self.solver = lm.ElasticNet(l1_ratio=l1_ratio,
                                        alpha=alpha,
                                        positive=True,
                                        warm_start=True)
        elif solver == 'NNLS' or solver == 'nnls':
            self.solver = opt.NonNegativeLeastSquares()

        elif (isinstance(solver, opt.SKLearnLinearSolver) or has_sklearn
              and isinstance(solver, sklearn.base.RegressorMixin)):
            self.solver = solver

        else:
            e_s = "The `solver` key-word argument needs to be: "
            e_s += "'ElasticNet', 'NNLS', or a "
            e_s += "`dipy.optimize.SKLearnLinearSolver` object"
            raise ValueError(e_s)
Exemplo n.º 19
0
    def __init__(self, gtab, split_b_D=400.0, split_b_S0=200., bounds=None,
                 two_stage=True, tol=1e-15,
                 x_scale=[1000., 0.1, 0.001, 0.0001],
                 options={'gtol': 1e-15, 'ftol': 1e-15,
                          'eps': 1e-15, 'maxiter': 1000}):
        """
        Initialize an IVIM model.

        The IVIM model assumes that biological tissue includes a volume
        fraction 'f' of water flowing with a pseudo-perfusion coefficient
        D* and a fraction (1-f) of static (diffusion only), intra and
        extracellular water, with a diffusion coefficient D. In this model
        the echo attenuation of a signal in a single voxel can be written as

            .. math::

            S(b) = S_0[f*e^{(-b*D\*)} + (1-f)e^{(-b*D)}]

            Where:
            .. math::

            S_0, f, D\* and D are the IVIM parameters.

        Parameters
        ----------
        gtab : GradientTable class instance
            Gradient directions and bvalues

        split_b_D : float, optional
            The b-value to split the data on for two-stage fit. This will be
            used while estimating the value of D. The assumption is that at
            higher b values the effects of perfusion is less and hence the
            signal can be approximated as a mono-exponential decay.
            default : 400.

        split_b_S0 : float, optional
            The b-value to split the data on for two-stage fit for estimation
            of S0 and initial guess for D_star. The assumption here is that
            at low bvalues the effects of perfusion are more.
            default : 200.

        bounds : tuple of arrays with 4 elements, optional
            Bounds to constrain the fitted model parameters. This is only
            supported for Scipy version > 0.17. When using a older Scipy
            version, this function will raise an error if bounds are different
            from None. This parameter is also used to fill nan values for out
            of bounds parameters in the `IvimFit` class using the method
            fill_na. default : ([0., 0., 0., 0.], [np.inf, .3, 1., 1.])

        two_stage : bool
            Argument to specify whether to perform a non-linear fitting of all
            parameters after the linear fitting by splitting the data based on
            bvalues. This gives more accurate parameters but takes more time.
            The linear fit can be used to get a quick estimation of the
            parameters. default : False

        tol : float, optional
            Tolerance for convergence of minimization.
            default : 1e-15

        x_scale : array, optional
            Scaling for the parameters. This is passed to `least_squares` which
            is only available for Scipy version > 0.17.
            default: [1000, 0.01, 0.001, 0.0001]

        options : dict, optional
            Dictionary containing gtol, ftol, eps and maxiter. This is passed
            to leastsq.
            default : options={'gtol': 1e-15, 'ftol': 1e-15, 'eps': 1e-15,
                      'maxiter': 1000}

        References
        ----------
        .. [1] Le Bihan, Denis, et al. "Separation of diffusion and perfusion
               in intravoxel incoherent motion MR imaging." Radiology 168.2
               (1988): 497-505.
        .. [2] Federau, Christian, et al. "Quantitative measurement of brain
               perfusion with intravoxel incoherent motion MR imaging."
               Radiology 265.3 (2012): 874-881.
        """
        if not np.any(gtab.b0s_mask):
            e_s = "No measured signal at bvalue == 0."
            e_s += "The IVIM model requires signal measured at 0 bvalue"
            raise ValueError(e_s)

        ReconstModel.__init__(self, gtab)
        self.split_b_D = split_b_D
        self.split_b_S0 = split_b_S0
        self.bounds = bounds
        self.two_stage = two_stage
        self.tol = tol
        self.options = options
        self.x_scale = x_scale

        if SCIPY_LESS_0_17 and self.bounds is not None:
            e_s = "Scipy versions less than 0.17 do not support "
            e_s += "bounds. Please update to Scipy 0.17 to use bounds"
            raise ValueError(e_s)
        elif self.bounds is None:
            self.bounds = ((0., 0., 0., 0.), (np.inf, .3, 1., 1.))
        else:
            self.bounds = bounds
Exemplo n.º 20
0
 def __init__(self, gtab):
     ReconstModel.__init__(self, gtab)
Exemplo n.º 21
0
    def __init__(self,
                 gtab,
                 split_b_D=400.0,
                 split_b_S0=200.,
                 bounds=None,
                 two_stage=True,
                 tol=1e-15,
                 x_scale=[1000., 0.1, 0.001, 0.0001],
                 gtol=1e-15,
                 ftol=1e-15,
                 eps=1e-15,
                 maxiter=1000):
        r"""
        Initialize an IVIM model.

        The IVIM model assumes that biological tissue includes a volume
        fraction 'f' of water flowing with a pseudo-diffusion coefficient
        D* and a fraction (1-f) of static (diffusion only), intra and
        extracellular water, with a diffusion coefficient D. In this model
        the echo attenuation of a signal in a single voxel can be written as

            .. math::

            S(b) = S_0[f*e^{(-b*D\*)} + (1-f)e^{(-b*D)}]

            Where:
            .. math::

            S_0, f, D\* and D are the IVIM parameters.

        Parameters
        ----------
        gtab : GradientTable class instance
            Gradient directions and bvalues

        split_b_D : float, optional
            The b-value to split the data on for two-stage fit. This will be
            used while estimating the value of D. The assumption is that at
            higher b values the effects of perfusion is less and hence the
            signal can be approximated as a mono-exponential decay.
            default : 400.

        split_b_S0 : float, optional
            The b-value to split the data on for two-stage fit for estimation
            of S0 and initial guess for D_star. The assumption here is that
            at low bvalues the effects of perfusion are more.
            default : 200.

        bounds : tuple of arrays with 4 elements, optional
            Bounds to constrain the fitted model parameters. This is only
            supported for Scipy version > 0.17. When using a older Scipy
            version, this function will raise an error if bounds are different
            from None. This parameter is also used to fill nan values for out
            of bounds parameters in the `IvimFit` class using the method
            fill_na. default : ([0., 0., 0., 0.], [np.inf, .3, 1., 1.])

        two_stage : bool
            Argument to specify whether to perform a non-linear fitting of all
            parameters after the linear fitting by splitting the data based on
            bvalues. This gives more accurate parameters but takes more time.
            The linear fit can be used to get a quick estimation of the
            parameters. default : False

        tol : float, optional
            Tolerance for convergence of minimization.
            default : 1e-15

        x_scale : array, optional
            Scaling for the parameters. This is passed to `least_squares` which
            is only available for Scipy version > 0.17.
            default: [1000, 0.01, 0.001, 0.0001]

        gtol : float, optional
            Tolerance for termination by the norm of the gradient.
            default : 1e-15

        ftol : float, optional
            Tolerance for termination by the change of the cost function.
            default : 1e-15

        eps : float, optional
            Step size used for numerical approximation of the jacobian.
            default : 1e-15

        maxiter : int, optional
            Maximum number of iterations to perform.
            default : 1000

        References
        ----------
        .. [1] Le Bihan, Denis, et al. "Separation of diffusion and perfusion
               in intravoxel incoherent motion MR imaging." Radiology 168.2
               (1988): 497-505.
        .. [2] Federau, Christian, et al. "Quantitative measurement of brain
               perfusion with intravoxel incoherent motion MR imaging."
               Radiology 265.3 (2012): 874-881.
        """
        if not np.any(gtab.b0s_mask):
            e_s = "No measured signal at bvalue == 0."
            e_s += "The IVIM model requires signal measured at 0 bvalue"
            raise ValueError(e_s)

        if gtab.b0_threshold > 0:
            b0_s = "The IVIM model requires a measurement at b==0. As of "
            b0_s += "version 0.15, the default b0_threshold for the "
            b0_s += "GradientTable object is set to 50, so if you used the "
            b0_s += "default settings to initialize the gtab input to the "
            b0_s += "IVIM model, you may have provided a gtab with "
            b0_s += "b0_threshold larger than 0. Please initialize the gtab "
            b0_s += "input with b0_threshold=0"
            raise ValueError(b0_s)

        ReconstModel.__init__(self, gtab)
        self.split_b_D = split_b_D
        self.split_b_S0 = split_b_S0
        self.bounds = bounds
        self.two_stage = two_stage
        self.tol = tol
        self.options = {
            'gtol': gtol,
            'ftol': ftol,
            'eps': eps,
            'maxiter': maxiter
        }
        self.x_scale = x_scale

        self.bounds = bounds or BOUNDS