Exemplo n.º 1
0
    def test_match_multiple(self):

        ms = MotifSet(preload_motifs="default")
        ms = ms.filter({'database': ["jaspar_vertebrates"], 'name': ["MA0139.1.CTCF"]}, search="inexact")

        self.assertEqual(len(ms), 1)

        motif = ms.get_motif_list(1, 0.0001)[0]

        scanner = scan.Scanner(7)

        pssm_list, thresholds = [], []

        thresholds.append(motif.threshold)
        thresholds.append(motif.threshold)
        pssm_list.append(motif.pssm)
        pssm_list.append(motif.pssm_rc)

        bg = tools.flat_bg(4)
        scanner.set_motifs(pssm_list, bg, thresholds)

        genomic_region = GenomicRegion("chr1", 0, 5022)

        # Reading sequence associated to genomic_region
        sequence = str(self.genome_file.fetch(genomic_region.chrom, genomic_region.initial, genomic_region.final))

        grs = match_multiple(scanner, [motif], sequence, genomic_region)

        self.assertSequenceEqual(grs.sequences,
                                 [GenomicRegion("chr1", 4270, 4289, name="MA0139.1.CTCF", orientation="+"),
                                  GenomicRegion("chr1", 4180, 4199, name="MA0139.1.CTCF", orientation="-")])
Exemplo n.º 2
0
 def test_create_default(self):
     ms = MotifSet()
     self.assertEqual(
         len(ms),
         0,
         msg="motif dictionary must be empty by default (no preload)")
     motif_list = ms.get_motif_list(1.0, 0.0001)
     self.assertEqual(len(motif_list), 0)
Exemplo n.º 3
0
 def test_create_empty(self):
     ms = MotifSet(preload_motifs=None)
     self.assertEqual(len(ms), 0, msg="motif dictionary must be empty")
     motif_list = ms.get_motif_list(1.0, 0.0001)
     self.assertEqual(len(motif_list), 0)
Exemplo n.º 4
0
 def test_create_default(self):
     ms = MotifSet()
     self.assertEqual(len(ms), 0, msg="motif dictionary must be empty by default (no preload)")
     motif_list = ms.get_motif_list(1.0, 0.0001)
     self.assertEqual(len(motif_list), 0)