Exemplo n.º 1
0
    def test_percentile_affinity_select_solutions(self):
        """
        Test whether selected `Antibody` objects were selected according
        to `PercentileAffinitySelector` rules.
        """
        antibodies = []
        affinities = [15, 20, 25, 30, 35, 40, 45, 50, 55, 60]
        negative_filtered_affinities = [[15, 20, 25, 30, 35], [15, 20, 25],
                                        [15, 20], [15]]

        positive_filtered_affinities = [[40, 45, 50, 55, 60], [50, 55, 60],
                                        [55, 60], [60]]

        for affinity in affinities:
            antibody = Antibody()
            antibody.affinity_value = affinity
            antibodies.append(antibody)

        negative_percentile_selector = PercentileAffinitySelector(
            affinity_threshold=50, select_type='negative')
        filtered_antibodies = copy.deepcopy(antibodies)
        for affinities_list in negative_filtered_affinities:
            filtered_antibodies = negative_percentile_selector.select(
                filtered_antibodies)

            for i, antibody in enumerate(filtered_antibodies):
                self.assertEqual(antibody.affinity_value,
                                 affinities_list[i],
                                 msg=f'Antibody had affinity value '
                                 f'`{antibody.affinity_value}`, expected '
                                 f'`{affinities_list[i]}`.')

        positive_percentile_selector = PercentileAffinitySelector(
            affinity_threshold=50, select_type='positive')
        filtered_antibodies = copy.deepcopy(antibodies)
        for affinities_list in positive_filtered_affinities:
            filtered_antibodies = positive_percentile_selector.select(
                filtered_antibodies)

            for i, antibody in enumerate(filtered_antibodies):
                self.assertEqual(antibody.affinity_value,
                                 affinities_list[i],
                                 msg=f'Antibody had affinity value '
                                 f'`{antibody.affinity_value}`, expected '
                                 f'`{affinities_list[i]}`.')
Exemplo n.º 2
0
    def test_basic_select_solutions(self):
        """
        Test whether selected `Antibody` objects were selected according
        to `BasicSelector` rules.
        """
        antibodies = []
        affinity_threshold = 30
        affinities = [15, 20, 25, 30, 35, 40, 45, 50, 55, 60]
        negative_filtered_affinities = [15, 20, 25, 30]
        positive_filtered_affinities = [30, 35, 40, 45, 50, 55, 60]

        for affinity in affinities:
            antibody = Antibody()
            antibody.affinity_value = affinity
            antibodies.append(antibody)

        negative_basic_selector = BasicSelector(
            affinity_threshold=affinity_threshold, select_type='negative')
        selected_antibodies = negative_basic_selector.select(antibodies)

        for antibody in selected_antibodies:
            self.assertTrue(
                antibody.affinity_value in negative_filtered_affinities,
                msg=f'Antibody had affinity value '
                f'`{antibody.affinity_value}`, expected value smaller or '
                f'equal to `{affinity_threshold}`.')

        positive_basic_selector = BasicSelector(
            affinity_threshold=affinity_threshold, select_type='positive')
        selected_antibodies = positive_basic_selector.select(antibodies)

        for antibody in selected_antibodies:
            self.assertTrue(
                antibody.affinity_value in positive_filtered_affinities,
                msg=f'Antibody had affinity value '
                f'`{antibody.affinity_value}`, expected value greater or '
                f'equal to `{affinity_threshold}`.')