Exemplo n.º 1
0
    def testDrawMiniAlignmentMarkUp(self):
        self.alignment, self.names = readMSA("./tests/test_files/example1.fasta")
        self.dest = "./tests/test_files/test_mini_markup.png"
        self.legend = "./tests/test_files/test_mini_markup_legend.png"
        expected = image.imread('./tests/test_files/expected_mini_ali_markup.png')
        markup_dict = {'remove_divergent': {'Seq1'},
                        'remove_gaponly': {89, 90, 91, 92, 93, 94, 95},
                        'remove_insertions': {22, 23, 24, 25, 26, 27},
                        'crop_ends': {'Seq5': ((np.array([]), np.array([92, 93, 94, 95])))},
                        'remove_short': {'Seq6'}}

        logger = logging.getLogger('path.to.module.under.test')
        with mock.patch.object(logger, 'debug') as mock_debug:
            miniAlignments.drawMiniAlignment(self.alignment, self.names,
                                             logger, self.dest,
                                             'nt', 300, None, 5, 3,
                                             True, markup_dict, False)

        mini_alignment = image.imread(self.dest)
        # added a bit of leeway to allow for images created on different
        # machines - they are visually identical but have minor differences
        # in rendering - look for 95% structural similarity
        simi = skimage.metrics.structural_similarity(expected,
                                                     mini_alignment,
                                                     multichannel=True)
        self.assertTrue(simi > 0.9)
Exemplo n.º 2
0
    def testRemoveShort(self, min_length, expected):
        exp_array, names = readMSA(expected)

        logger = logging.getLogger('path.to.module.under.test')
        with mock.patch.object(logger, 'debug') as mock_debug:
            result_ali, r = parsingFunctions.removeTooShort(self.in_array, self.nams, self.rm_file, mock_debug, min_length)

        self.assertTrue((result_ali == exp_array).all())
        self.assertGreaterEqual(len(self.in_array), len(result_ali))
Exemplo n.º 3
0
    def testRemoveGapOnly(self):
        expected = "./tests/test_files/remove_gaponly_cleaned.fasta"
        exp_array, names = readMSA(expected)

        logger = logging.getLogger('path.to.module.under.test')
        with mock.patch.object(logger, 'debug') as mock_debug:
            result_ali, r, self.relativePositions = parsingFunctions.removeGapOnly(self.in_array, self.relativePositions, self.rm_file, mock_debug)

        self.assertTrue((result_ali == exp_array).all())
        self.assertEqual(len(self.in_array), len(result_ali))
Exemplo n.º 4
0
    def testCropEnds(self, mingap, redefine_perc, expected):
        exp_array, names = readMSA(expected)

        logger = logging.getLogger('path.to.module.under.test')
        with mock.patch.object(logger, 'debug') as mock_debug:
            result_ali, names = parsingFunctions.cropEnds(self.in_array, self.nams, self.relativePositions, self.rm_file, mock_debug, mingap, redefine_perc)

        self.assertEqual(result_ali[0,:].size, exp_array[0,:].size)
        self.assertEqual(len(self.in_array), len(result_ali))
        self.assertTrue((result_ali == exp_array).all())
Exemplo n.º 5
0
    def testRemoveInsertions(self, min_size, max_size, min_flank, expected):
        exp_array, names = readMSA(expected)

        logger = logging.getLogger('path.to.module.under.test')
        with mock.patch.object(logger, 'debug') as mock_debug:
            result_ali, r, self.relativePositions = parsingFunctions.removeInsertions(self.in_array, self.relativePositions, self.rm_file, mock_debug, min_size, max_size, min_flank)
        # check if dimensions are equal first
        self.assertEqual(result_ali[0,:].size, exp_array[0,:].size)
        self.assertEqual(len(self.in_array), len(result_ali))
        self.assertTrue((result_ali == exp_array).all())
Exemplo n.º 6
0
    def testFindConsensus(self, MSA, type, expected_consensus,
                          expected_coverage):
        alignment, names = readMSA(MSA)

        logger = logging.getLogger('path.to.module.under.test')
        with mock.patch.object(logger, 'debug') as mock_debug:
            consensus, coverage = consensusSeq.findConsensus(
                alignment, logger, type)
        coverage_rounded = [round(num, 2) for num in coverage]
        self.assertEqual(consensus, expected_consensus)
        self.assertEqual(coverage_rounded, expected_coverage)
Exemplo n.º 7
0
    def testRemoveDivergent(self, percidentity, expected):
        exp_array, names = readMSA(expected)

        logger = logging.getLogger('path.to.module.under.test')
        with mock.patch.object(logger, 'debug') as mock_debug:
            result_ali, r = parsingFunctions.removeDivergent(self.in_array, self.nams, self.rm_file, mock_debug, percidentity)

        self.assertEqual(result_ali[0,:].size, exp_array[0,:].size)
        self.assertEqual(result_ali[:,0].size, exp_array[:,0].size)
        self.assertGreaterEqual(len(self.in_array), len(result_ali))
        self.assertTrue((result_ali == exp_array).all())
Exemplo n.º 8
0
    def testArrNumeric(self):
        alignment, names = readMSA("./tests/test_files/consensus_example_nt.fasta")
        arr_expected = [[1, 3, 3, 3, 3, 3, 3, 3, 3, 4, 4, 0, 4, 2, 4, 3],
                    [1, 1, 1, 3, 3, 3, 3, 3, 3, 4, 4, 0, 4, 2, 4, 2],
                    [1, 1, 1, 3, 3, 3, 3, 3, 3, 4, 4, 0, 0, 1, 2, 4],
                    [1, 1, 1, 2, 4, 2, 4, 4, 0, 4, 4, 0, 4, 2, 4, 2],
                    [4, 2, 1, 3, 3, 3, 3, 3, 3, 4, 4, 0, 4, 2, 4, 2],
                    [2, 4, 0, 3, 3, 3, 3, 3, 3, 4, 2, 1, 2, 4, 0, 2],]

        arr_int, colour_map = miniAlignments.arrNumeric(alignment,'nt')

        self.assertTrue((arr_int == arr_expected).all())
Exemplo n.º 9
0
 def setUp(self):
     self.dest = "./tests/test_files/test_mini.png"
     self.alignment, self.names = readMSA("./tests/test_files/example1.fasta")
     self.ali_width = len(self.alignment[0])
     self.ali_height = len(self.alignment)
     self.markup_dict = {'remove_divergent': {'Seq1'},
                     'remove_gaponly': {89, 90, 91, 92, 93, 94, 95},
                     'remove_insertions': {22, 23, 24, 25, 26, 27},
                     'crop_ends': {'Seq5': ((np.array([]), np.array([92, 93, 94, 95])))},
                     'remove_short': {'Seq6'}}
     logger = logging.getLogger('path.to.module.under.test')
     with mock.patch.object(logger, 'debug') as mock_debug:
         # make mini plot without markup
         self.mini_plot = miniAlignments.drawMiniAlignment(self.alignment, self.names, logger, self.dest,
                                                             'nt', 300, None, 5, 3,
                                                             False, None, True)
         # make mini plot with markup
         self.mini_plot_expected = miniAlignments.drawMiniAlignment(self.alignment, self.names, logger, self.dest,
                                                             'nt', 300, None, 5, 3,
                                                             True, self.markup_dict, True)
Exemplo n.º 10
0
    def testDrawMiniAlignment(self, input, expected, type):
        self.alignment, self.names = readMSA(input)
        self.dest = "./tests/test_files/test_mini.png"
        self.legend = ""
        expected = image.imread(expected)

        logger = logging.getLogger('path.to.module.under.test')
        with mock.patch.object(logger, 'debug') as mock_debug:
            miniAlignments.drawMiniAlignment(self.alignment, self.names, logger, self.dest,
                                                                type, 300, None, 5, 3,
                                                                False, None, False)

        mini_alignment = image.imread(self.dest)
        
        # added a bit of leeway to allow for images created on different
        # machines - they are visually identical but have minor differences
        # in rendering - look for 95% structural similarity
        simi = skimage.metrics.structural_similarity(expected,
                                                     mini_alignment,
                                                     multichannel=True)
        self.assertTrue(simi > 0.9)
Exemplo n.º 11
0
 def testMakeCoveragePlot(self):
     alignment, names = readMSA(
         "./tests/test_files/consensus_example_aa.fasta")
     consensusSeq.sequence_bar_logo(alignment, self.dest, 'aa')
     self.assertTrue(os.path.isfile(self.dest))
Exemplo n.º 12
0
 def setUp(self):
     self.in_array, self.nams = readMSA("./tests/test_files/example1.fasta")
     self.relativePositions = list(range(0, len(self.in_array[0])))
     self.rm_file = 'mock_rmfile.txt'
Exemplo n.º 13
0
    def testSeqType(self, input, expected):
        in_array, names = readMSA(input)

        type = utilityFunctions.seqType(in_array)

        self.assertEqual(type, expected)
Exemplo n.º 14
0
 def setUp(self):
     self.input = "./tests/test_files/example1.fasta"
     self.in_array, self.nams = readMSA(self.input)
     self.removed = set()
     self.outfile = "writeOutfile_test.txt"
Exemplo n.º 15
0
 def setUp(self):
     self.input = "./tests/test_files/example1.fasta"
     self.in_array, self.nams = readMSA(self.input)
Exemplo n.º 16
0
 def setUp(self):
     self.in_array, self.nams = readMSA(
         "./tests/test_files/remove_gaponly_cleaned.fasta")