def test_draw_overlay(self):
gene = genomic.Gene('12',
25357723,
25403870,
strand=STRAND.NEG,
name='KRAS')
marker = BioInterval('12', 25403865, name='splice site mutation')
t = build_transcript(cds_start=193,
cds_end=759,
exons=[(25403685, 25403865), (25398208, 25398329),
(25380168, 25380346), (25378548, 25378707),
(25357723, 25362845)],
gene=gene,
domains=[])
build_transcript(cds_start=198,
cds_end=425,
exons=[(25403685, 25403870), (25398208, 25398329),
(25362102, 25362845)],
gene=gene,
domains=[])
build_transcript(cds_start=65,
cds_end=634,
exons=[(25403685, 25403737), (25398208, 25398329),
(25380168, 25380346), (25378548, 25378707),
(25368371, 25368494), (25362365, 25362845)],
gene=gene,
domains=[
protein.Domain('domain1', [(1, 10)]),
protein.Domain('domain1', [(4, 10)])
],
is_best_transcript=True)
build_transcript(cds_start=65,
cds_end=634,
exons=[(25403698, 25403863), (25398208, 25398329),
(25386753, 25388160)],
gene=gene,
domains=[])
d = DiagramSettings()
for i, t in enumerate(gene.transcripts):
t.name = 'transcript {}'.format(i + 1)
scatterx = [x + 100 for x in range(gene.start, gene.end + 1, 400)]
scattery = [random.uniform(-0.2, 0.2) for x in scatterx]
s = ScatterPlot(list(zip(scatterx, scattery)),
'cna',
ymin=-1,
ymax=1,
yticks=[-1, 0, 1])
d.gene_min_buffer = 0
canvas = draw_multi_transcript_overlay(d,
gene,
vmarkers=[marker],
plots=[s, s])
self.assertEqual(2, len(canvas.elements)) # defs counts as element
if OUTPUT_SVG:
canvas.saveas('test_draw_overlay.svg')
def test_generate_gene_mapping_err(self):
# _generate_interval_mapping [genomic.IntergenicRegion(11:77361962_77361962+)] 1181.39453125 5 30 None 77356962 77366962)
ir = genomic.IntergenicRegion('11', 5000, 5000, STRAND.POS)
tgt_width = 1000
d = DiagramSettings()
d.gene_min_buffer = 10
# (self, canvas, gene, width, height, fill, label='', reference_genome=None)
draw_genes(d, self.canvas, [ir], tgt_width, [])
# _generate_interval_mapping ['Interval(29684391, 29684391)', 'Interval(29663998, 29696515)'] 1181.39453125 5 60 None 29662998 29697515
# def generate_interval_mapping(cls, input_intervals, target_width, ratio, min_width, buffer_length=None, start=None, end=None, min_inter_width=None)
itvls = [Interval(29684391, 29684391), Interval(29663998, 29696515)]
generate_interval_mapping(itvls, 1181.39, 5, 60, None, 29662998,
29697515)