Пример #1
0
    def test_elasticsearch_status(self):
        url = reverse(elasticsearch_status)
        self.check_data_manager_login(url)

        urllib3_responses.add_json(
            '/_cat/allocation?format=json&h=node,shards,disk.avail,disk.used,disk.percent',
            ES_CAT_ALLOCATION)
        urllib3_responses.add_json(
            '/_cat/nodes?format=json&h=name,heap.percent', ES_CAT_NODES)
        urllib3_responses.add_json(
            '/_cat/indices?format=json&h=index,docs.count,store.size,creation.date.string',
            ES_CAT_INDICES)
        urllib3_responses.add_json('/_cat/aliases?format=json&h=alias,index',
                                   ES_CAT_ALIAS)
        urllib3_responses.add_json('/_all/_mapping', ES_INDEX_MAPPING)

        response = self.client.get(url)
        self.assertEqual(response.status_code, 200)
        response_json = response.json()
        self.assertSetEqual(
            set(response_json.keys()),
            {'indices', 'errors', 'diskStats', 'elasticsearchHost'})

        self.assertEqual(len(response_json['indices']), 5)
        self.assertDictEqual(response_json['indices'][0],
                             TEST_INDEX_EXPECTED_DICT)
        self.assertDictEqual(response_json['indices'][3],
                             TEST_INDEX_NO_PROJECT_EXPECTED_DICT)
        self.assertDictEqual(response_json['indices'][4],
                             TEST_SV_INDEX_EXPECTED_DICT)

        self.assertListEqual(response_json['errors'], EXPECTED_ERRORS)

        self.assertListEqual(response_json['diskStats'],
                             EXPECTED_DISK_ALLOCATION)
Пример #2
0
    def test_delete_index(self):
        url = reverse(delete_index)
        self.check_data_manager_login(url)

        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({'index': 'test_index'}))
        self.assertEqual(response.status_code, 403)
        self.assertDictEqual(response.json(), ({
            'error':
            'Index "test_index" is still used by: 1kg project n\xe5me with uni\xe7\xf8de'
        }))
        self.assertEqual(len(urllib3_responses.calls), 0)

        urllib3_responses.add_json(
            '/_cat/indices?format=json&h=index,docs.count,store.size,creation.date.string',
            ES_CAT_INDICES)
        urllib3_responses.add_json('/_cat/aliases?format=json&h=alias,index',
                                   ES_CAT_ALIAS)
        urllib3_responses.add_json('/_all/_mapping', ES_INDEX_MAPPING)
        urllib3_responses.add(urllib3_responses.DELETE, '/unused_index')

        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({'index': 'unused_index'}))
        self.assertEqual(response.status_code, 200)
        response_json = response.json()
        self.assertSetEqual(set(response_json.keys()), {'indices'})
        self.assertEqual(len(response_json['indices']), 5)
        self.assertDictEqual(response_json['indices'][0],
                             TEST_INDEX_EXPECTED_DICT)
        self.assertDictEqual(response_json['indices'][3],
                             TEST_INDEX_NO_PROJECT_EXPECTED_DICT)
        self.assertDictEqual(response_json['indices'][4],
                             TEST_SV_INDEX_EXPECTED_DICT)

        self.assertEqual(urllib3_responses.calls[0].request.method, 'DELETE')
Пример #3
0
    def test_add_variants_dataset(self, mock_open, mock_random, mock_redis):
        mock_file_iter = mock_open.return_value.__enter__.return_value.__iter__

        url = reverse(add_variants_dataset_handler, args=[PROJECT_GUID])
        self.check_data_manager_login(url)

        # Confirm test DB is as expected
        existing_index_sample = Sample.objects.get(sample_id='NA19675')
        self.assertEqual(existing_index_sample.elasticsearch_index, INDEX_NAME)
        self.assertTrue(existing_index_sample.is_active)
        existing_index_sample_guid = existing_index_sample.guid
        existing_old_index_sample = Sample.objects.get(guid='S000130_na19678')
        self.assertNotEqual(existing_old_index_sample.elasticsearch_index,
                            INDEX_NAME)
        self.assertTrue(existing_old_index_sample.is_active)
        existing_old_index_sample_guid = existing_old_index_sample.guid
        existing_sample = Sample.objects.get(sample_id='NA19679')
        self.assertEqual(existing_sample.elasticsearch_index, INDEX_NAME)
        self.assertFalse(existing_sample.is_active)
        existing_sample_guid = existing_sample.guid
        self.assertEqual(
            Sample.objects.filter(sample_id='NA19678_1').count(), 0)

        mock_random.return_value = 98765432101234567890

        urllib3_responses.add_json(
            '/{}/_mapping'.format(INDEX_NAME), {
                INDEX_NAME: {
                    'mappings': {
                        "properties": MAPPING_PROPS_SAMPLES_NUM_ALT_1
                    }
                }
            })
        urllib3_responses.add_json(
            '/{}/_search?size=0'.format(INDEX_NAME),
            {'aggregations': {
                'sample_ids': {
                    'buckets': []
                }
            }},
            method=urllib3_responses.POST)

        # Send invalid requests
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({}))
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'request must contain fields: elasticsearchIndex, datasetType'
                ]
            })

        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({
                                        'elasticsearchIndex': INDEX_NAME,
                                        'datasetType': 'NOT_A_TYPE'
                                    }))
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(response.json(),
                             {'errors': ['Invalid dataset type "NOT_A_TYPE"']})

        response = self.client.post(url,
                                    content_type='application/json',
                                    data=ADD_DATASET_PAYLOAD)
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'No samples found in the index. Make sure the specified caller type is correct'
                ]
            })

        self.assertEqual(len(urllib3_responses.calls), 2)
        self.assertDictEqual(
            urllib3_responses.call_request_json(), {
                'aggs': {
                    'sample_ids': {
                        'terms': {
                            'field': 'samples_num_alt_1',
                            'size': 10000
                        }
                    }
                }
            })

        urllib3_responses.replace_json(
            '/{}/_search?size=0'.format(INDEX_NAME), {
                'aggregations': {
                    'sample_ids': {
                        'buckets': [{
                            'key': 'NA19679'
                        }, {
                            'key': 'NA19678_1'
                        }]
                    }
                }
            },
            method=urllib3_responses.POST)
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=ADD_DATASET_PAYLOAD)
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'Index metadata must contain fields: genomeVersion, sampleType, sourceFilePath'
                ]
            })

        urllib3_responses.replace_json(
            '/{}/_mapping'.format(INDEX_NAME), {
                INDEX_NAME: {
                    'mappings': {
                        '_meta': {
                            'sampleType': 'NOT_A_TYPE',
                            'genomeVersion': '37',
                            'sourceFilePath': 'invalidpath.txt',
                        },
                        "properties": MAPPING_PROPS_SAMPLES_NUM_ALT_1
                    }
                }
            })
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=ADD_DATASET_PAYLOAD)
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(),
            {'errors': ['Sample type not supported: NOT_A_TYPE']})

        urllib3_responses.replace_json(
            '/{}/_mapping'.format(INDEX_NAME), {
                INDEX_NAME: {
                    'mappings': {
                        '_meta': {
                            'sampleType': 'WES',
                            'genomeVersion': '38',
                            'sourceFilePath': 'invalidpath.txt',
                        },
                        "properties": MAPPING_PROPS_SAMPLES_NUM_ALT_1
                    }
                }
            })
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=ADD_DATASET_PAYLOAD)
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'Index "test_index" has genome version 38 but this project uses version 37'
                ]
            })

        urllib3_responses.replace_json(
            '/{}/_mapping'.format(INDEX_NAME), {
                INDEX_NAME: {
                    'mappings': {
                        '_meta': {
                            'sampleType': 'WES',
                            'genomeVersion': '37',
                            'sourceFilePath': 'invalidpath.txt',
                        },
                        "properties": MAPPING_PROPS_SAMPLES_NUM_ALT_1
                    }
                }
            })
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=ADD_DATASET_PAYLOAD)
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'Variant call dataset path must end with .vds or .vcf.gz or .bgz or .bed'
                ]
            })

        urllib3_responses.replace_json(
            '/{}/_mapping'.format(INDEX_NAME), {
                INDEX_NAME: {
                    'mappings': {
                        '_meta': {
                            'sampleType': 'WES',
                            'genomeVersion': '37',
                            'sourceFilePath': 'test_data.vds',
                            'datasetType': 'SV',
                        },
                        "properties": MAPPING_PROPS_WITH_SAMPLES
                    }
                }
            })
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=ADD_DATASET_PAYLOAD)
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'Index "test_index" has dataset type SV but expects VARIANTS'
                ]
            })

        urllib3_responses.replace_json(
            '/{}/_mapping'.format(INDEX_NAME), {
                INDEX_NAME: {
                    'mappings': {
                        '_meta': {
                            'sampleType': 'WES',
                            'genomeVersion': '37',
                            'sourceFilePath': 'test_data.vds',
                        },
                        "properties": MAPPING_PROPS_SAMPLES_NUM_ALT_1
                    }
                }
            })
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=ADD_DATASET_PAYLOAD)
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'Matches not found for ES sample ids: NA19678_1. Uploading a mapping file for these samples, or select the "Ignore extra samples in callset" checkbox to ignore.'
                ]
            })

        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({
                                        'elasticsearchIndex':
                                        INDEX_NAME,
                                        'datasetType':
                                        'VARIANTS',
                                        'ignoreExtraSamplesInCallset':
                                        True,
                                    }))
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'The following families are included in the callset but are missing some family members: 1 (NA19675_1, NA19678).'
                ]
            })

        urllib3_responses.replace_json('/{}/_search?size=0'.format(INDEX_NAME),
                                       {
                                           'aggregations': {
                                               'sample_ids': {
                                                   'buckets': [{
                                                       'key': 'NA19673'
                                                   }]
                                               }
                                           }
                                       },
                                       method=urllib3_responses.POST)
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({
                                        'elasticsearchIndex':
                                        INDEX_NAME,
                                        'datasetType':
                                        'VARIANTS',
                                        'ignoreExtraSamplesInCallset':
                                        True,
                                    }))
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(
            response.json(), {
                'errors': [
                    'None of the individuals or samples in the project matched the 1 expected sample id(s)'
                ]
            })

        mock_file_iter.return_value = StringIO('NA19678_1,NA19678,metadata\n')
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({
                                        'elasticsearchIndex': INDEX_NAME,
                                        'mappingFilePath': 'mapping.csv',
                                        'datasetType': 'VARIANTS',
                                    }))
        self.assertEqual(response.status_code, 400)
        self.assertDictEqual(response.json(), {
            'errors': ['Must contain 2 columns: NA19678_1, NA19678, metadata']
        })

        # Send valid request
        urllib3_responses.replace_json(
            '/{}/_search?size=0'.format(INDEX_NAME), {
                'aggregations': {
                    'sample_ids': {
                        'buckets': [{
                            'key': 'NA19675'
                        }, {
                            'key': 'NA19679'
                        }, {
                            'key': 'NA19678_1'
                        }]
                    }
                }
            },
            method=urllib3_responses.POST)
        mock_file_iter.return_value = StringIO('NA19678_1,NA19678\n')
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({
                                        'elasticsearchIndex': INDEX_NAME,
                                        'mappingFilePath': 'mapping.csv',
                                        'datasetType': 'VARIANTS',
                                    }))
        self.assertEqual(response.status_code, 200)
        mock_open.assert_called_with('mapping.csv', 'r')
        mock_redis.return_value.get.assert_called_with(
            'index_metadata__test_index')
        mock_redis.return_value.set.assert_called_with(
            'index_metadata__test_index',
            '{"test_index": {"sampleType": "WES", "genomeVersion": "37", "sourceFilePath": "test_data.vds", "fields": {"samples_num_alt_1": "keyword"}}}'
        )

        response_json = response.json()
        self.assertSetEqual(
            set(response_json.keys()),
            {'samplesByGuid', 'individualsByGuid', 'familiesByGuid'})

        new_sample_guid = 'S98765432101234567890_NA19678_'
        self.assertSetEqual(
            set(response_json['samplesByGuid'].keys()), {
                existing_index_sample_guid, existing_sample_guid,
                existing_old_index_sample_guid, new_sample_guid
            })
        self.assertDictEqual(
            response_json['individualsByGuid'], {
                'I000001_na19675': {
                    'sampleGuids': [existing_index_sample_guid]
                },
                'I000002_na19678': {
                    'sampleGuids': mock.ANY
                },
                'I000003_na19679': {
                    'sampleGuids': [existing_sample_guid]
                },
            })
        self.assertSetEqual(
            set(response_json['individualsByGuid']['I000002_na19678']
                ['sampleGuids']),
            {new_sample_guid, existing_old_index_sample_guid})
        self.assertDictEqual(response_json['familiesByGuid'],
                             {'F000001_1': {
                                 'analysisStatus': 'I'
                             }})
        updated_samples = [
            sample
            for sample_guid, sample in response_json['samplesByGuid'].items()
            if sample_guid != existing_old_index_sample_guid
        ]
        self.assertSetEqual(
            {'WES'}, {sample['sampleType']
                      for sample in updated_samples})
        self.assertSetEqual({True},
                            {sample['isActive']
                             for sample in updated_samples})
        self.assertDictEqual(
            response_json['samplesByGuid'][existing_old_index_sample_guid],
            {'isActive': False})

        # Only the new/updated samples should have an updated loaded date
        self.assertTrue(
            response_json['samplesByGuid'][existing_index_sample_guid]
            ['loadedDate'].startswith('2017-02-05'))
        today = datetime.now().strftime('%Y-%m-%d')
        self.assertTrue(response_json['samplesByGuid'][existing_sample_guid]
                        ['loadedDate'].startswith(today))
        self.assertTrue(response_json['samplesByGuid'][new_sample_guid]
                        ['loadedDate'].startswith(today))

        updated_sample_models = Sample.objects.filter(
            guid__in=[sample['sampleGuid'] for sample in updated_samples])
        self.assertEqual(len(updated_sample_models), 3)
        self.assertSetEqual(
            {INDEX_NAME},
            {sample.elasticsearch_index
             for sample in updated_sample_models})

        # Adding an SV index works additively with the regular variants index
        mock_random.return_value = 1234567
        urllib3_responses.add_json(
            '/{}/_mapping'.format(SV_INDEX_NAME), {
                SV_INDEX_NAME: {
                    'mappings': {
                        '_meta': {
                            'sampleType': 'WES',
                            'genomeVersion': '37',
                            'sourceFilePath': 'test_data.bed',
                            'datasetType': 'SV',
                        },
                        "properties": MAPPING_PROPS_WITH_SAMPLES
                    }
                }
            })
        urllib3_responses.add_json('/{}/_search?size=0'.format(SV_INDEX_NAME),
                                   {
                                       'aggregations': {
                                           'sample_ids': {
                                               'buckets': [{
                                                   'key': 'NA19675_1'
                                               }]
                                           }
                                       }
                                   },
                                   method=urllib3_responses.POST)
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({
                                        'elasticsearchIndex': SV_INDEX_NAME,
                                        'datasetType': 'SV',
                                    }))
        self.assertEqual(response.status_code, 200)

        self.assertDictEqual(urllib3_responses.call_request_json(), {
            'aggs': {
                'sample_ids': {
                    'terms': {
                        'field': 'samples',
                        'size': 10000
                    }
                }
            }
        })

        response_json = response.json()
        self.assertSetEqual(
            set(response_json.keys()),
            {'samplesByGuid', 'individualsByGuid', 'familiesByGuid'})
        sv_sample_guid = 'S1234567_NA19675_1'
        self.assertDictEqual(response_json['familiesByGuid'], {})
        self.assertListEqual(list(response_json['samplesByGuid'].keys()),
                             [sv_sample_guid])
        self.assertEqual(
            response_json['samplesByGuid'][sv_sample_guid]['datasetType'],
            'SV')
        self.assertEqual(
            response_json['samplesByGuid'][sv_sample_guid]['sampleType'],
            'WES')
        self.assertTrue(
            response_json['samplesByGuid'][sv_sample_guid]['isActive'])
        self.assertListEqual(list(response_json['individualsByGuid'].keys()),
                             ['I000001_na19675'])
        self.assertListEqual(
            list(response_json['individualsByGuid']['I000001_na19675'].keys()),
            ['sampleGuids'])
        self.assertSetEqual(
            set(response_json['individualsByGuid']['I000001_na19675']
                ['sampleGuids']),
            set([sv_sample_guid, existing_index_sample_guid]))

        # Regular variant sample should still be active
        sample_models = Sample.objects.filter(
            individual__guid='I000001_na19675')
        self.assertEqual(len(sample_models), 2)
        self.assertSetEqual({sv_sample_guid, existing_index_sample_guid},
                            {sample.guid
                             for sample in sample_models})
        self.assertSetEqual({True},
                            {sample.is_active
                             for sample in sample_models})

        # Adding an index for a different sample type works additively
        mock_random.return_value = 987654
        urllib3_responses.add_json(
            '/{}/_mapping'.format(NEW_SAMPLE_TYPE_INDEX_NAME), {
                NEW_SAMPLE_TYPE_INDEX_NAME: {
                    'mappings': {
                        '_meta': {
                            'sampleType': 'WGS',
                            'genomeVersion': '37',
                            'sourceFilePath': 'test_data.vds',
                        },
                        "properties": MAPPING_PROPS_SAMPLES_NUM_ALT_1
                    }
                }
            })
        urllib3_responses.add_json(
            '/{}/_search?size=0'.format(NEW_SAMPLE_TYPE_INDEX_NAME), {
                'aggregations': {
                    'sample_ids': {
                        'buckets': [{
                            'key': 'NA19675_1'
                        }]
                    }
                }
            },
            method=urllib3_responses.POST)
        response = self.client.post(url,
                                    content_type='application/json',
                                    data=json.dumps({
                                        'elasticsearchIndex':
                                        NEW_SAMPLE_TYPE_INDEX_NAME,
                                        'datasetType': 'VARIANTS',
                                    }))
        self.assertEqual(response.status_code, 200)

        response_json = response.json()
        self.assertSetEqual(
            set(response_json.keys()),
            {'samplesByGuid', 'individualsByGuid', 'familiesByGuid'})
        new_sample_type_sample_guid = 'S987654_NA19675_1'
        self.assertDictEqual(response_json['familiesByGuid'], {})
        self.assertListEqual(list(response_json['samplesByGuid'].keys()),
                             [new_sample_type_sample_guid])
        self.assertEqual(
            response_json['samplesByGuid'][new_sample_type_sample_guid]
            ['datasetType'], 'VARIANTS')
        self.assertEqual(
            response_json['samplesByGuid'][new_sample_type_sample_guid]
            ['sampleType'], 'WGS')
        self.assertTrue(response_json['samplesByGuid']
                        [new_sample_type_sample_guid]['isActive'])
        self.assertListEqual(list(response_json['individualsByGuid'].keys()),
                             ['I000001_na19675'])
        self.assertListEqual(
            list(response_json['individualsByGuid']['I000001_na19675'].keys()),
            ['sampleGuids'])
        self.assertSetEqual(
            set(response_json['individualsByGuid']['I000001_na19675']
                ['sampleGuids']),
            set([
                sv_sample_guid, existing_index_sample_guid,
                new_sample_type_sample_guid
            ]))

        # Previous variant samples should still be active
        sample_models = Sample.objects.filter(
            individual__guid='I000001_na19675')
        self.assertEqual(len(sample_models), 3)
        self.assertSetEqual(
            {
                sv_sample_guid, existing_index_sample_guid,
                new_sample_type_sample_guid
            }, {sample.guid
                for sample in sample_models})
        self.assertSetEqual({True},
                            {sample.is_active
                             for sample in sample_models})