def test_evidence_init(self):
entity = Reaction()
target = Gene("id2")
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence(entity=entity,
eco=eco,
assertion=assertion,
comment=comment,
target=target)
evidence.add_reference(reference)
# Check proper linking
assert evidence.entity is entity
assert evidence in entity.evidences
assert evidence.target is target
assert evidence in target.evidences
# Check attributes
assert evidence.assertion == assertion
assert evidence.eco == eco
assert evidence.comment == comment
# Check id is set
assert type(evidence.internal_id) is str
assert evidence.internal_id != ""
# Check the references
assert reference in evidence.references
assert evidence in reference.linked_items
def test_copy_evidence(self):
entity = Reaction()
target = Gene()
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence(entity=entity,
eco=eco,
assertion=assertion,
comment=comment,
target=target)
evidence.add_reference(reference)
# Create copy
copy = evidence.copy()
# Check the correctness of the copy
assert evidence.entity is copy.entity
assert evidence.target is copy.target
assert evidence.eco == copy.eco
assert evidence.assertion == copy.assertion
assert evidence.comment == copy.comment
assert evidence.references == copy.references
assert evidence.references is not copy.references
# Check that the copy is not linked
assert copy not in entity.evidences
assert copy not in reference.linked_items
assert copy not in target.evidences
def save_state(self):
genes_added = 0
for gene_id in self.plainTextEdit.toPlainText().split("\n"):
try:
gene = self.model.genes.get_by_id(gene_id.strip())
except KeyError:
if self.comboBox_missing.currentText() == "Add":
gene = Gene(gene_id.strip())
self.model.add_gene(gene)
self.model.QtGeneTable.update_row_from_item(gene)
genes_added += 1
else:
continue
# Generate an evidence item for each gene
evidence = Evidence(entity=gene,
eco=self.evidence.eco,
assertion=self.evidence.assertion,
comment=self.evidence.comment,
target=self.evidence.target)
# Add reference
for reference in self.evidence.references:
evidence.add_reference(reference)
# Add evidence to model
self.model.all_evidences[evidence.internal_id] = evidence
if genes_added:
QMessageBox(self).information(
self, "Genes added",
"{} new genes added!".format(str(genes_added)))
def complete_evidence(self):
evidence = Evidence(entity=self.entity,
assertion=self.assertion,
target=self.target,
eco=self.eco,
comment=self.comment)
evidence.add_reference(self.reference)
return evidence
def test_saving_changes(self):
reaction = Reaction()
reference = Reference()
model = Model()
evidence = Evidence(entity=reaction)
evidence.add_reference(reference)
widget = EvidenceDisplayWidget()
model.all_evidences[evidence.internal_id] = evidence
assert evidence in reaction.evidences
assert evidence.internal_id in model.all_evidences
assert reference in evidence.references
# Set reaction and model to widget
widget.set_item(reaction, model)
assert widget.dataTable.rowCount() == 1
# Remove evidence copy from data table
widget.dataTable.setRowCount(0)
# Setup new evidence item
new_evidence = Evidence()
new_evidence.assertion = "Catalyzed by"
new_evidence.entity = reaction
reference = Reference()
new_evidence.add_reference(reference, reciprocal=False)
# Test the setup i.e. that items are only linked in a one way (evidence -> item) fashion
assert new_evidence not in reaction.evidences
assert new_evidence not in reference.linked_items
# Add new reference to widget table
widget.dataTable.update_row_from_item(new_evidence)
assert widget.dataTable.rowCount() == 1
assert widget.dataTable.item(0).link is new_evidence
# Action - Save evidences
widget.save_state()
# Check that old instance is detached from all links
assert evidence not in reaction.evidences
assert len(evidence.references) == 0
# Old evidence still kept alive by this test
old_id = evidence.internal_id
assert old_id in model.all_evidences
evidence = None
gc.collect()
assert old_id not in model.all_evidences
# Check that new evidence is linked properly
assert new_evidence in reaction.evidences
assert new_evidence.internal_id in model.all_evidences
def parse_evidences_from_xml(model_node, model, progress=None):
list_of_evidences_node = model_node.find(ge_listOfEvidences)
if list_of_evidences_node is None:
return
elif progress is None:
pass
elif not progress.wasCanceled():
progress.setLabelText("Reading evidences...")
progress.setRange(0, len(list_of_evidences_node))
else:
return
for i, evidence_node in enumerate(
list_of_evidences_node.iterfind(ge_evidence)):
if progress is None:
pass
elif not progress.wasCanceled():
progress.setValue(i)
QApplication.processEvents()
else:
return
new_evidence = Evidence(internal_id=evidence_node.get("id"),
assertion=evidence_node.get("assertion"),
comment=evidence_node.get("comment"),
eco=evidence_node.get("eco"))
entity_id = evidence_node.get("entity_id")
entity_type = evidence_node.get("entity_type")
entity = get_item_from_model(entity_type, entity_id, model)
new_evidence.set_entity(entity)
# Add target item if present
target_id = evidence_node.get("target_id")
target_type = evidence_node.get("target_type")
if target_id and target_type:
target = get_item_from_model(target_type, target_id, model)
new_evidence.set_target(target)
# Add all references if present
reference_list_node = evidence_node.find(ge_listOfReferenceLinks)
if reference_list_node is not None:
for refLink_node in reference_list_node.iterfind(ge_referenceLink):
new_evidence.add_reference(
model.references[refLink_node.get("id")])
model.all_evidences[new_evidence.internal_id] = new_evidence
def test_equality(self):
entity = Reaction()
target = Gene()
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence(entity=entity,
eco=eco,
assertion=assertion,
comment=comment,
target=target)
evidence.add_reference(reference)
assert evidence.copy() == evidence
def test_override_entity(self):
entity = Reaction()
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence(entity=entity,
eco=eco,
assertion=assertion,
comment=comment)
evidence.add_reference(reference)
new_reaction = Reaction()
evidence.set_entity(new_reaction)
# Check disconnection of old reaction
assert evidence.entity is new_reaction
assert evidence not in entity.evidences
def test_inequality(self, attribute, new_value):
entity = Reaction()
target = Gene()
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence(entity=entity,
eco=eco,
assertion=assertion,
comment=comment,
target=target)
evidence.add_reference(reference)
new_copy = evidence.copy()
setattr(new_copy, attribute, new_value)
assert new_copy != evidence
assert not new_copy == evidence
def test_inequality_reference(self):
entity = Reaction()
target = Gene()
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence(entity=entity,
eco=eco,
assertion=assertion,
comment=comment,
target=target)
evidence.add_reference(reference)
new_copy = evidence.copy()
new_copy.remove_all_references()
assert new_copy != evidence
assert not new_copy == evidence
def test_delete_links(self):
entity = Reaction()
target = Gene()
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence(entity=entity,
eco=eco,
assertion=assertion,
comment=comment,
target=target)
evidence.add_reference(reference)
evidence.delete_links()
assert evidence.entity is None
assert len(evidence.references) == 0
assert evidence not in entity.evidences
assert evidence not in target.evidences
def test_override_target(self):
entity = Reaction()
target = Gene()
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence(entity=entity,
eco=eco,
assertion=assertion,
comment=comment,
target=target)
evidence.add_reference(reference)
new_gene = Gene()
evidence.set_target(new_gene)
# Check disconnection of old reaction
assert evidence.target is new_gene
assert evidence not in target.evidences
def test_setup_links(self):
entity = Reaction()
target = Gene()
eco = "ECO:000000"
assertion = "Presence"
comment = "test comment"
reference = Reference()
evidence = Evidence()
evidence.entity = entity
evidence.target = target
evidence.eco = eco
evidence.assertion = assertion
evidence.comment = comment
evidence.add_reference(reference, reciprocal=False)
assert evidence not in entity.evidences
assert evidence not in reference.linked_items
assert evidence not in target.evidences
evidence.setup_links()
assert evidence in entity.evidences
assert evidence in reference.linked_items
assert evidence in target.evidences
class TestModelDeleteItems:
@pytest.fixture(autouse=True)
def setup_complete_model(self):
self.model = Model("model")
# Setup reaction1
self.metabolite = Metabolite("m1")
self.reaction = Reaction("r1")
self.gene = Gene("g1")
self.reaction.add_child(self.gene)
self.model.add_genes((self.gene,))
self.reaction.add_metabolites({self.metabolite: -1})
self.model.add_reactions((self.reaction,))
# Setup reaction2
self.metabolite2 = Metabolite("m2")
self.reaction2 = Reaction("r2")
self.gene2 = Gene("g2")
self.genegroup = GeneGroup()
self.genegroup.add_child(self.gene2)
self.reaction2.add_child(self.genegroup)
self.model.add_genes((self.gene2,))
self.reaction2.add_metabolites({self.metabolite2: 1})
self.model.add_reactions((self.reaction2,))
# Setup evidences
self.evidence = Evidence(assertion="Catalyzes")
self.evidence.set_entity(self.gene)
self.evidence.set_target(self.reaction)
self.reference = Reference()
self.model.add_reference(self.reference)
self.evidence.add_reference(self.reference)
self.model.add_evidence(self.evidence)
# Setup test case
self.testcase = ModelTest()
reaction_setting = ReactionSetting(self.reaction, 1000., -1000., 0.)
gene_setting = GeneSetting(gene=self.gene2, activity=False)
outcome = Outcome(self.reaction2, 0., "greater")
self.testcase.add_outcome(outcome)
self.testcase.add_setting(gene_setting)
self.testcase.add_setting(reaction_setting)
self.model.add_test(self.testcase)
self.reference2 = Reference()
self.model.add_reference(self.reference2)
self.testcase.add_reference(self.reference2)
self.model.setup_tables()
def test_setup(self):
# Test genes
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model)
# Test evidences
evidence_in_model(self.evidence, self.model)
# Test model test
case_in_model(self.testcase, self.model)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction)
gene_in_reaction(self.gene2, self.reaction2)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction)
metabolite_in_reaction(self.metabolite2, self.reaction2)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence)
item_in_evidence(self.reaction, self.evidence)
def test_deletion_metabolite(self):
# Action
self.model.gem_remove_metabolites((self.metabolite,))
# Test gene
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model, valid=False)
metabolite_in_model(self.metabolite2, self.model)
# Test evidences
evidence_in_model(self.evidence, self.model)
# Test model test
case_in_model(self.testcase, self.model)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction)
gene_in_reaction(self.gene2, self.reaction2)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction, valid=False)
metabolite_in_reaction(self.metabolite2, self.reaction2)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence)
item_in_evidence(self.reaction, self.evidence)
def test_deletion_metabolite2(self):
# Action
self.model.gem_remove_metabolites((self.metabolite2,))
# Test genes
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model, valid=False)
# Test evidences
evidence_in_model(self.evidence, self.model)
# Test model test
case_in_model(self.testcase, self.model)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction)
gene_in_reaction(self.gene2, self.reaction2)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction)
metabolite_in_reaction(self.metabolite2, self.reaction2, valid=False)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence)
item_in_evidence(self.reaction, self.evidence)
def test_delete_reaction1(self):
####
# Delete reaction
# Check:
# - gene present but removed from reaction1
# - metabolite present but removed from reaction1
# - reaction deleted
# - evidence deleted
# - testcase deleted
# - reference present but removed from evidence
# - reference2 present but removed from testcase
####
# Action
self.model.gem_remove_reactions((self.reaction,))
# Test genes
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model, valid=False)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model)
# Test model test
case_in_model(self.testcase, self.model, valid=False)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence, valid=False)
reference_in_item(self.reference2, self.testcase, valid=False)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction, valid=False)
gene_in_reaction(self.gene2, self.reaction2)
# Metabolite1 <-> Reaction1
# Check metabolite is still in reaction, but reaction not in metabolite
assert self.metabolite in self.reaction.metabolites
assert self.reaction not in self.metabolite.reactions
metabolite_in_reaction(self.metabolite2, self.reaction2)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence, valid=False)
item_in_evidence(self.reaction, self.evidence, valid=False)
# Check evidence is removed when reference deleted
del self.evidence
gc.collect()
assert len(self.model.all_evidences) == 0
def test_deletion_reaction2(self):
# Check:
# - reaction2 removed
# - test case removed
# - reference removed from testcase
# - gene2 removed from reaction
# Action
self.model.gem_remove_reactions((self.reaction2,))
# Test genes
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model, valid=False)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model)
# Test evidences
evidence_in_model(self.evidence, self.model)
# Test model test
case_in_model(self.testcase, self.model, valid=False)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase, valid=False)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction)
gene_in_reaction(self.gene2, self.reaction2, valid=False)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction)
# Check metabolite still in reaction, but reaction not in metabolite
assert self.metabolite2 in self.reaction2.metabolites
assert self.reaction2 not in self.metabolite2.reactions
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence)
item_in_evidence(self.reaction, self.evidence)
def test_delete_gene1(self):
# Test gene deletion
# Check:
# - Gene removed from model
# - Evidence removed from model
# Action
self.model.gem_remove_genes((self.gene,))
# Test genes
gene_in_model(self.gene, self.model, valid=False)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model)
# Test model test
case_in_model(self.testcase, self.model)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence, valid=False)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction, valid=False)
gene_in_reaction(self.gene2, self.reaction2)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction)
metabolite_in_reaction(self.metabolite2, self.reaction2)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence, valid=False)
item_in_evidence(self.reaction, self.evidence, valid=False)
# Check evidence is removed when reference deleted
del self.evidence
gc.collect()
assert len(self.model.all_evidences) == 0
def test_delete_gene2(self):
# Test removal of gene2
# Check:
# - Gene2 removed from model
# - Gene2 removed from reaction2
# - Testcase deleted from model
# - Reference2 removed from testcase
# Action
self.model.gem_remove_genes((self.gene2,))
# Test genes
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model, valid=False)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model)
# Test evidences
evidence_in_model(self.evidence, self.model)
# Test model test
case_in_model(self.testcase, self.model, valid=False)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase, valid=False)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction)
gene_in_reaction(self.gene2, self.reaction2, valid=False)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction)
metabolite_in_reaction(self.metabolite2, self.reaction2)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence)
item_in_evidence(self.reaction, self.evidence)
def test_delete_testcase(self):
# Action
self.model.gem_remove_tests((self.testcase,))
# Test genes
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model)
# Test evidences
evidence_in_model(self.evidence, self.model)
# Test model test
case_in_model(self.testcase, self.model, valid=False)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase, valid=False)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction)
gene_in_reaction(self.gene2, self.reaction2)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction)
metabolite_in_reaction(self.metabolite2, self.reaction2)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence)
item_in_evidence(self.reaction, self.evidence)
def test_delete_referenec(self):
# Action
self.model.gem_remove_references((self.reference,))
# Test genes
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model)
# Test evidences
evidence_in_model(self.evidence, self.model)
# Test model test
case_in_model(self.testcase, self.model)
# Test references
reference_in_model(self.reference, self.model, valid=False)
reference_in_model(self.reference2, self.model)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence, valid=False)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction)
gene_in_reaction(self.gene2, self.reaction2)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction)
metabolite_in_reaction(self.metabolite2, self.reaction2)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence)
item_in_evidence(self.reaction, self.evidence)
def test_delete_reference2(self):
# Action
self.model.gem_remove_references((self.reference2,))
# Test genes
gene_in_model(self.gene, self.model)
gene_in_model(self.gene2, self.model)
# Test reactions
reaction_in_model(self.reaction, self.model)
reaction_in_model(self.reaction2, self.model)
# Test metabolites
metabolite_in_model(self.metabolite, self.model)
metabolite_in_model(self.metabolite2, self.model)
# Test evidences
evidence_in_model(self.evidence, self.model)
# Test model test
case_in_model(self.testcase, self.model)
# Test references
reference_in_model(self.reference, self.model)
reference_in_model(self.reference2, self.model, valid=False)
# Test connections
# Reference <-> Evidence
reference_in_item(self.reference, self.evidence)
# Reference2 <-> Testcase
reference_in_item(self.reference2, self.testcase, valid=False)
# Gene1 <-> Reaction1
gene_in_reaction(self.gene, self.reaction)
gene_in_reaction(self.gene2, self.reaction2)
# Metabolite1 <-> Reaction1
metabolite_in_reaction(self.metabolite, self.reaction)
metabolite_in_reaction(self.metabolite2, self.reaction2)
# Evidence <-> Gene1/Reaction
item_in_evidence(self.gene, self.evidence)
item_in_evidence(self.reaction, self.evidence)
class TestEvidence:
@pytest.fixture(autouse=True)
def setup_evidence(self):
self.reaction = Reaction("r_id")
self.gene = Gene("g_id")
self.target = Gene("g_id2")
self.model = Model("test id")
self.reference = Reference()
self.model.add_gene(self.gene)
self.model.add_gene(self.target)
self.model.add_reactions([self.reaction])
self.model.add_reference(self.reference)
# Set type
self.assertion = "Catalyzed by"
self.eco = "ECO:0000000"
self.comment = "test"
self.evidence = Evidence(entity=self.reaction, eco=self.eco,
assertion=self.assertion, comment=self.comment, target=self.target)
self.evidence.add_reference(self.reference)
self.model.all_evidences[self.evidence.internal_id] = self.evidence
self.root = Element("root", nsmap={None: ge_ns})
def test_setup(self):
assert self.evidence.entity is self.reaction
assert self.evidence.target is self.target
assert len(self.evidence.references) == 1
assert list(self.evidence.references)[0] is self.reference
assert self.evidence.assertion == self.assertion
assert self.evidence.eco == self.eco
assert self.evidence.comment == self.comment
def test_add_evidence(self):
add_evidences_to_xml(self.root, self.model)
list_of_evidences = self.root.find(ge_listOfEvidences)
assert list_of_evidences is not None
assert len(list_of_evidences) == 1
evidence_node = list_of_evidences.find(ge_evidence)
assert evidence_node is not None
assert evidence_node.get("entity_id") == self.reaction.id
assert evidence_node.get("entity_type") == "Reaction"
assert evidence_node.get("id") == self.evidence.internal_id
assert evidence_node.get("comment") == self.comment
assert evidence_node.get("target_id") == self.target.id
assert evidence_node.get("target_type") == "Gene"
assert evidence_node.get("assertion") == self.assertion
assert evidence_node.get("eco") == self.eco
evidence_references_node = evidence_node.find(ge_listOfReferenceLinks)
assert evidence_references_node is not None
assert len(evidence_references_node) == 1
reference_link_node = evidence_references_node.find(ge_referenceLink)
assert reference_link_node is not None
assert reference_link_node.get("id") == self.reference.id
def test_no_references_added_if_empty(self):
self.evidence.remove_all_references()
add_evidences_to_xml(self.root, self.model)
list_of_evidences = self.root.find(ge_listOfEvidences)
assert list_of_evidences is not None
evidence_node = list_of_evidences.find(ge_evidence)
assert evidence_node is not None
# Check that reference not is not found
assert evidence_node.find(ge_listOfReferenceLinks) is None
def test_write_parse_consistency(self):
add_evidences_to_xml(self.root, self.model)
model = Model("New model")
model.add_gene(self.gene)
model.add_gene(self.target)
model.add_reactions([self.reaction])
model.add_reference(self.reference)
assert len(model.all_evidences) == 0
parse_evidences_from_xml(self.root, model)
assert len(model.all_evidences) == 1
evidence = model.all_evidences[self.evidence.internal_id]
assert evidence == self.evidence
def test_get_item_from_model(self):
model = Model("test id")
reaction = Reaction("r_id")
metabolite = Metabolite("m_id")
gene = Gene("g_id")
# ToDo: Add gene group
model.add_reactions([reaction])
model.add_metabolites([metabolite]),
model.add_gene(gene)
# ToDo: Add gene group
assert get_item_from_model("Model", model.id, model) is model
assert get_item_from_model("Reaction", reaction.id, model) is reaction
assert get_item_from_model("Metabolite", metabolite.id, model) is metabolite
assert get_item_from_model("Gene", gene.id, model) is gene
# Test expected errors
# GeneGroup not implemented
with pytest.raises(NotImplementedError):
get_item_from_model("GeneGroup", "test_id", model)
# ID not in model
with pytest.raises(KeyError):
get_item_from_model("Reaction", "Not in model", model)
with pytest.raises(KeyError):
get_item_from_model("Metabolite", "Not in model", model)
with pytest.raises(KeyError):
get_item_from_model("Gene", "Not in model", model)
def test_minimal_example(self):
""" Test that a minimal evidence example is parsed correctly """
xml_tree = ET.fromstring(minimal_evidence)
model = Model()
reaction = Reaction("Test")
model.add_reaction(reaction)
assert len(model.all_evidences) == 0
assert len(reaction.evidences) == 0
parse_evidences_from_xml(xml_tree, model)
assert len(model.all_evidences) == 1
assert len(reaction.evidences) == 1
evidence = list(reaction.evidences)[0]
assert evidence.entity is reaction
assert evidence.assertion == "Presence"
def test_full_example(self):
""" Test that a minimal evidence example is parsed correctly """
xml_tree = ET.fromstring(full_evidence)
model = Model()
reaction = Reaction("Test")
target_item = Gene("target_id")
reference = Reference("ref_id")
model.add_reaction(reaction)
model.add_gene(target_item)
model.add_reference(reference)
assert len(model.all_evidences) == 0
assert len(reaction.evidences) == 0
parse_evidences_from_xml(xml_tree, model)
assert len(model.all_evidences) == 1
assert len(reaction.evidences) == 1
evidence = list(reaction.evidences)[0]
assert evidence.entity is reaction
assert evidence.target is target_item
assert evidence.assertion == "Catalyzed by"
assert evidence.eco == "ECO:0000000"
assert len(evidence.references) == 1
assert list(evidence.references)[0] is reference
assert evidence.comment == "test comment"
