class tXmapFile(tFile_base): def setUp(self): with open(self.input_file, "w"): self.obj=XmapFile(self.input_file) def test_getExtension(self): self.assertEquals("xmap", XmapFile.getExtension()) def test_parse(self): expected=XmapFile_iter(self.input_file) self.assertEqual(expected, self.obj.parse()) def test_write(self): expected="1 2 3 1.0 2.0 1.0 2.0 + 999.9 1DM 1.0 1.0 1 (1,1)(1,2)\n" alignment=Mock(alignment_id=1, query_id=2, anchor_id=3, query_start=1.0, query_end=2.0, anchor_start=1.0, anchor_end=2.0, orientation="+", confidence=999.9, hit_enum="1DM", query_len=1.0, anchor_len=1.0, label_channel="1", alignment="(1,1)(1,2)") with open("test_file", "w") as o_file: self.obj.write(alignment, o_file) with open("test_file") as i_file: actual=i_file.readline() os.remove("test_file") self.assertEqual(expected, actual)
class tFindBreakpoints(tScripts): maxDiff=None xmap_name='file.xmap' xmap_writer=None xmap=None query_cmap_name='file_r.cmap' query_cmap=None anchor_cmap_name='file_q.cmap' anchor_cmap=None cmap_writer=None def setUp(self): self.xmap=open(self.xmap_name, 'w') self.xmap_writer=XmapFile(self.xmap_name) self.query_cmap=open(self.query_cmap_name, 'w') self.anchor_cmap=open(self.anchor_cmap_name, 'w') self.cmap_writer=CmapFile(self.query_cmap_name) def tearDown(self): self.xmap.close() self.query_cmap.close() self.anchor_cmap.close() os.remove(self.xmap_name) os.remove(self.query_cmap_name) os.remove(self.anchor_cmap_name) ### Bad input ### def test_badInput_none(self): expected_stdout="usage: find_breakpoints.py [-h] xmap_file\nfind_breakpoints.py: error: too few arguments\n" expected_returnCode=2 expecteds=[expected_stdout, expected_returnCode] actual_stdout=None try: actual_stdout=subprocess.check_output("../scripts/find_breakpoints.py", stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] self.assertEquals(expecteds, actuals) def test_badInput_notAFile(self): expected_stdout="The .xmap alignment file you specified, file.xmap.bed.ext, could not be found\n" expected_returnCode=1 expecteds=[expected_stdout, expected_returnCode] actual_stdout=None try: actual_stdout=subprocess.check_output(["../scripts/find_breakpoints.py",self.xmap_name+".bed.ext"], stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] self.assertEquals(expecteds, actuals) @unittest.skip('not_implemented') def test_badInput_notXmap(self): pass def test_badInput_contigInXmapNotInAnchorCmap(self): for label_position in xrange(1,1000): label=Mock(contig_id=1, contig_len=1000, contig_site_count=1000, label_id=label_position, channel="1", position=label_position, stdev=0, coverage=1, occurrences=1) self.cmap_writer.write(label, self.query_cmap) self.query_cmap.close() alignment=Mock(alignment_id=1, query_id=1, anchor_id=1, query_start=2, query_end=998, anchor_start=1, anchor_end=1000, orientation='+', confidence=250,hit_enum="*", query_len=1000, anchor_len=1000, label_channel="1", alignment="*") self.xmap_writer.write(alignment, self.xmap) self.xmap.close() expected_stdout="The .xmap alignment ("+self.xmap_name+") file contains a contig id (1) that was not found in one of the .cmap contig files ("+self.anchor_cmap_name+")\n" expected_returnCode=1 expecteds=[expected_stdout, expected_returnCode] try: actual_stdout=subprocess.check_output(["../scripts/find_breakpoints.py",self.xmap_name], stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] self.assertEquals(expecteds, actuals) def test_badInput_contigInXmapNotInQueryCmap(self): for label_position in xrange(1,1000): label=Mock(contig_id=1, contig_len=1000, contig_site_count=1000, label_id=label_position, channel="1", position=label_position, stdev=0, coverage=1, occurrences=1) self.cmap_writer.write(label, self.anchor_cmap) self.anchor_cmap.close() alignment=Mock(alignment_id=1, query_id=1, anchor_id=1, query_start=2, query_end=998, anchor_start=1, anchor_end=1000, orientation='+', confidence=250,hit_enum="*", query_len=1000, anchor_len=1000, label_channel="1", alignment="*") self.xmap_writer.write(alignment, self.xmap) self.xmap.close() expected_stdout="The .xmap alignment ("+self.xmap_name+") file contains a contig id (1) that was not found in one of the .cmap contig files ("+self.query_cmap_name+")\n" expected_returnCode=1 expecteds=[expected_stdout, expected_returnCode] try: actual_stdout=subprocess.check_output(["../scripts/find_breakpoints.py",self.xmap_name], stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] self.assertEquals(expecteds, actuals) def test_badInput_cantFindCmap(self): os.remove(self.query_cmap_name) os.remove(self.anchor_cmap_name) expected_stdout="Some of the .cmap contig files associated with your .xmap alignment file could not be found. More specifically, Unable to find query, anchor maps.\n" expected_returnCode=1 expecteds=[expected_stdout, expected_returnCode] actual_stdout=None try: actual_stdout=subprocess.check_output(["../scripts/find_breakpoints.py",self.xmap_name], stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] with open(self.query_cmap_name, 'w'): pass with open(self.anchor_cmap_name, 'w'): pass self.assertEquals(expecteds, actuals) ### One alignment only ### def test_oneAlignment_no5PercentOverhang(self): for label_position in xrange(1,1000): label=Mock(contig_id=1, contig_len=1000, contig_site_count=1000, label_id=label_position, channel="1", position=label_position, stdev=0, coverage=1, occurrences=1) self.cmap_writer.write(label, self.query_cmap) self.cmap_writer.write(label, self.anchor_cmap) self.query_cmap.close() self.anchor_cmap.close() alignment=Mock(alignment_id=1, query_id=1, anchor_id=1, query_start=2, query_end=998, anchor_start=1, anchor_end=1000, orientation='+', confidence=250,hit_enum="*", query_len=1000, anchor_len=1000, label_channel="1", alignment="*") self.xmap_writer.write(alignment, self.xmap) self.xmap.close() expected_stdout="" expected_returnCode=0 expecteds=[expected_stdout, expected_returnCode] try: actual_stdout=subprocess.check_output(["../scripts/find_breakpoints.py",self.xmap_name], stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] self.assertEquals(expecteds, actuals) def test_oneAlignment_noLabeledOverhang(self): for label_position in xrange(1,500): label=Mock(contig_id=1, contig_len=1000, contig_site_count=1000, label_id=label_position, channel="1", position=label_position, stdev=0, coverage=1, occurrences=1) self.cmap_writer.write(label, self.query_cmap) self.cmap_writer.write(label, self.anchor_cmap) self.query_cmap.close() self.anchor_cmap.close() alignment=Mock(alignment_id=1, query_id=1, anchor_id=1, query_start=2, query_end=500, anchor_start=1, anchor_end=500, orientation='+', confidence=250,hit_enum="*", query_len=1000, anchor_len=1000, label_channel="1", alignment="*") self.xmap_writer.write(alignment, self.xmap) self.xmap.close() expected_stdout="" expected_returnCode=0 expecteds=[expected_stdout, expected_returnCode] try: actual_stdout=subprocess.check_output(["../scripts/find_breakpoints.py",self.xmap_name], stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] self.assertEquals(expecteds, actuals) def test_oneAlignment_oneSingleLabelOverhang(self): for label_position in xrange(1,502): label=Mock(contig_id=1, contig_len=1000, contig_site_count=1000, label_id=label_position, channel="1", position=label_position, stdev=0, coverage=1, occurrences=1) self.cmap_writer.write(label, self.query_cmap) self.cmap_writer.write(label, self.anchor_cmap) self.query_cmap.close() self.anchor_cmap.close() alignment=Mock(alignment_id=1, query_id=1, anchor_id=1, query_start=2, query_end=500, anchor_start=1, anchor_end=500, orientation='+', confidence=250,hit_enum="*", query_len=1000, anchor_len=1000, label_channel="1", alignment="*") self.xmap_writer.write(alignment, self.xmap) self.xmap.close() expected_stdout="Chr01\t500\t501\t1\t250.0\t+\n" expected_returnCode=0 expecteds=[expected_stdout, expected_returnCode] try: actual_stdout=subprocess.check_output(["../scripts/find_breakpoints.py",self.xmap_name], stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] self.assertEquals(expecteds, actuals) def test_oneAlignment_oneLabeledOverhang(self): for label_position in xrange(1,1000): label=Mock(contig_id=1, contig_len=1000, contig_site_count=1000, label_id=label_position, channel="1", position=label_position, stdev=0, coverage=1, occurrences=1) self.cmap_writer.write(label, self.query_cmap) self.cmap_writer.write(label, self.anchor_cmap) self.query_cmap.close() self.anchor_cmap.close() alignment=Mock(alignment_id=1, query_id=1, anchor_id=1, query_start=2, query_end=500, anchor_start=1, anchor_end=500, orientation='+', confidence=250,hit_enum="*", query_len=1000, anchor_len=1000, label_channel="1", alignment="*") self.xmap_writer.write(alignment, self.xmap) self.xmap.close() expected_stdout="Chr01\t500\t502\t1\t250.0\t+\n" expected_returnCode=0 expecteds=[expected_stdout, expected_returnCode] try: actual_stdout=subprocess.check_output(["../scripts/find_breakpoints.py",self.xmap_name], stderr=subprocess.STDOUT) actual_returnCode=0 except subprocess.CalledProcessError as error: actual_stdout=error.output actual_returnCode=error.returncode except: raise actuals=[actual_stdout, actual_returnCode] self.assertEquals(expecteds, actuals) ### Multiple alignments ### @unittest.skip('not implmemented') def test_multipleAligns_noTwoLabelOverhang(self): pass