def __init__(self,parent=None, signalManager = None):
OWWidget.__init__(self, parent, signalManager, "&Display Motifs", 0)
# set default settings
self.colorBy = None
self.pvalThresholdIndex = None
self.pvalThreshold = None
#load settings
self.loadSettings()
# GUI
self.graph = OWGraph(self.mainArea)
self.graph.setYRlabels(None)
self.graph.enableGridXB(0)
self.graph.enableGridYL(1)
self.graph.setAxisMaxMinor(QwtPlot.xBottom, 10)
self.graph.setAxisMaxMajor(QwtPlot.xBottom, 10)
self.graph.setAxisAutoScale(QwtPlot.xBottom)
self.graph.setAxisScale(QwtPlot.xBottom, -1020, 0, 0)
self.mainArea.layout().addWidget(self.graph)
# inputs
# data and graph temp variables
self.inputs = [("Examples", ExampleTable, self.cdata, Default), ("Genes", list, self.newGeneList, Default), ("Motifs", list, self.newMotifList, Default)]
self.data = None
self.motifLines = []
self.visibleValues = []
self.valueToCurve = {}
self.allGenes = [] ## genes displayed always in same order
self.geneList = [] ## selected genes
self.motifList = [] ## selected motifs
self.valuesPresentInData = []
self.clusterPostProbThreshold = 0
# GUI
self.selValues = OWGUI.widgetBox(self.controlArea, "Values")
self.selcolorBy = OWGUI.widgetBox(self.controlArea, "Color By")
self.colorByCombo = OWGUI.comboBox(self.selcolorBy, self, "colorBy",
items=[],
callback=self.colorByChanged)
self.pvalThresholdCombo = OWGUI.comboBox(self.selValues, self, "pvalThresholdIndex",
items=[],
callback=self.pvalThresholdChanged)
self.valuesQLB = QListWidget(self.selValues)
self.valuesQLB.setSelectionMode(QListWidget.MultiSelection)
self.connect(self.valuesQLB, SIGNAL("itemSelectionChanged()"), self.valuesSelectionChange)
self.selValues.layout().addWidget(self.valuesQLB)
self.unselectAllQLB = OWGUI.button(self.selValues, self, "Unselect all",
callback = self.unselAll)
def __init__(self, parent=None, signalManager = None):
OWWidget.__init__(self, parent, signalManager, 'Process Chip Data')
self.callbackDeposit = []
self.inputs = [("Structured Data", DataFiles, self.chipdata)]
self.outputs = [("Structured Data", DataFiles)]
self.chipdata = None; self.datasets = None
self.std = [("No preprocessing", None),
("Array-based standardization", chipstat.standardize_arrays),
("Gene-based standardization", chipstat.standardize_genes),
("First array-, then gene-based standardization", lambda e,r: chipstat.standardize_genes(chipstat.standardize_arrays(e,r),r)),
("First gene-, then array-based standardization", lambda e,r: chipstat.standardize_arrays(chipstat.standardize_genes(e,r),r))]
# Settings
self.data = None
self.preStdMethod = 0; self.preStdRob = 1
self.postStdMethod = 0; self.postStdRob = 1
self.mergeType = 0
self.commitOnChange = 0
self.loadSettings()
# GUI
# info
box = QVGroupBox("Info", self.controlArea)
self.infoa = QLabel('No data on input.', box)
self.infob = QLabel('', box)
# preprocessing
OWGUI.separator(self.controlArea)
box = QVGroupBox("Preprocessing", self.controlArea)
labels = [x[0] for x in self.std]
OWGUI.comboBox(box, self, 'preStdMethod', label=None, labelWidth=None, orientation='vertical', items=labels, callback=self.selectionChange)
self.preRobBtn = OWGUI.checkBox(box, self, "preStdRob", "Robust standardization", callback=self.selectionChange)
# merge
OWGUI.separator(self.controlArea)
self.mergeTypes = [(0, "No merging"), ('mean', 'Mean'), ('median', 'Median'), ('min', 'Minimum expression'), ('max', 'Maximum expression')]
labels = [x[1] for x in self.mergeTypes]
OWGUI.radioButtonsInBox(self.controlArea, self, 'mergeType', labels, box='Merge Replicas', tooltips=None, callback=self.selectionChange)
# postprocessing
OWGUI.separator(self.controlArea)
self.boxPostproc = QVGroupBox("Postprocessing", self.controlArea)
labels = [x[0] for x in self.std]
OWGUI.comboBox(self.boxPostproc, self, 'postStdMethod', label=None, labelWidth=None, orientation='vertical', items=labels, callback=self.selectionChange)
self.postRobBtn = OWGUI.checkBox(self.boxPostproc, self, "postStdRob", "Robust standardization", callback=self.selectionChange)
# output
OWGUI.separator(self.controlArea)
box = QVGroupBox("Output", self.controlArea)
OWGUI.checkBox(box, self, 'commitOnChange', 'Commit data on selection change')
self.commitBtn = OWGUI.button(box, self, "Commit", callback=self.selectionChange, disabled=1)
self.setBtnsState()
self.resize(100,100)
def __init__(self, parent=None, signalManager = None, name='Approximate Profiles'):
self.callbackDeposit = [] # deposit for OWGUI callback functions
OWWidget.__init__(self, parent, signalManager, name)
self._data = None # exampleTable
self._dataN = None # 2d numeric array
self._chipdata = None # [(dirname0, [et0, et1, ...]), ...]
self._chipdataN = None # 3d numeric array
self.kernel = 0
self.kernels = ["Orthogonal polynomials", "Trigonometric functions"]
self.kernelSize = None
self.kernelSizes = [ ["Const"] + map(lambda x: "degree <= %i"%x, range(1,99)),
["Const", "cos x", "sin x"] + reduce(lambda x,y: x+[y[0],y[1]], map(lambda i: ("cos %ix"%i, "sin %ix"%i), range(2,99)), [])
]
self.useSignificance = 0
self.alpha = 3
self.alphas = [0.0001, 0.001, 0.01, 0.05, 0.1, 0.2, 0.5]
self.commitOnChange = 1
# Settings
self.loadSettings()
# GUI: info, comboKernelSize, cbUseSignificance, vboxSignificance, commitBtn
# info
box = QVGroupBox("Info", self.controlArea)
self.infoa = QLabel("No examples on input", box)
OWGUI.separator(box,250)
self.infob = QLabel("No structured data on input", box)
OWGUI.separator(self.controlArea)
# kernel selection
box = QVGroupBox("Kernel functions", self.controlArea)
OWGUI.comboBox(box, self, "kernel", items=self.kernels, callback=self.kernelChange)
OWGUI.separator(self.controlArea)
# kernel settings
box = QVGroupBox("Kernel settings", self.controlArea)
self.comboKernelSize = OWGUI.comboBox(box, self, "kernelSize", callback=self.kernelSizeChange, label="Number of kernel functions", labelWidth=135, orientation="horizontal", valueType=int)
self.comboKernelSize.setDisabled(1)
self.cbUseSignificance = OWGUI.checkBox(box, self, "useSignificance", "Significance of coefficients (F-statistics)", callback=self.useSignificanceChange, tooltip="Use kernels with coefficients significantly different from 0.")
self.vboxSignificance = QVBox(box)
OWGUI.comboBox(self.vboxSignificance, self, "alpha", items = self.alphas, callback=self.alphaChange, label="p <", labelWidth=20, orientation="horizontal")
OWGUI.separator(self.controlArea)
# output
box = QVGroupBox("Output", self.controlArea)
OWGUI.checkBox(box, self, 'commitOnChange', 'Commit data on selection change')
self.commitBtn = OWGUI.button(box, self, "Commit", callback=self.senddata, disabled=1)
self.inputs = [("Examples", ExampleTable, self.data), ("Structured Data", DataFiles, self.chipdata)]
self.outputs = [("Approximated Examples", ExampleTable, Default), ("Approximation Coefficients", ExampleTable), ("Approximated Structured Data", DataFiles, Default), ("Structured Approximation Coefficients", DataFiles)]
self.resize(200,100)
def __init__(self, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager, 'Data Distance')
self.inputs = [("Structured Data", DataFiles, self.chipdata)]
self.outputs = [("Distance Matrix", orange.SymMatrix)]
self.Metrics = 0
self.loadSettings()
self.data = []
## self.metrics = [("Euclidean", orange.ExamplesDistanceConstructor_Euclidean),
## ("Manhattan", orange.ExamplesDistanceConstructor_Manhattan),
## ("Hamming", orange.ExamplesDistanceConstructor_Hamming)]
self.metrics = [("Manhattan", distManhattan),
("Euclidean", distEuclidean),
("1 - (Pearson correlation coefficient)", distPearson),
("1 - (Spearman rank correlation coefficient)",
distSpearman)]
# GUI
self.mainArea.setFixedWidth(0)
# Info box
box = QVGroupBox("Info", self.controlArea)
self.infoa = QLabel('No data on input.', box)
self.infob = QLabel('', box)
OWGUI.separator(self.controlArea)
# Distance metrics selection
items = [x[0] for x in self.metrics]
OWGUI.comboBox(
self.controlArea,
self,
"Metrics",
box="Distance Metrics",
items=items,
tooltip="Metrics to measure distance between data sets.",
callback=self.onMetricsChange)
self.resize(384, 138)
def __init__(self, parent=None, signalManager = None):
# self.callbackDeposit = [] # deposit for OWGUI callback functions
OWWidget.__init__(self, parent, signalManager, 'Expression Profiles', 1)
#set default settings
self.ShowAverageProfile = 1
self.ShowSingleProfiles = 0
self.PointWidth = 2
self.CurveWidth = 1
self.AverageCurveWidth = 4
self.BoxPlotWidth = 2
self.SelectedClasses = []
self.Classes = []
self.autoSendSelected = 0
self.selectionChangedFlag = False
self.CutLow = 0; self.CutHigh = 0; self.CutEnabled = 0
self.profileLabel = None
#load settings
self.loadSettings()
# GUI
self.graph = profilesGraph(self, self.mainArea, "")
self.mainArea.layout().addWidget(self.graph)
self.graph.hide()
self.connect(self.graphButton, SIGNAL("clicked()"), self.graph.saveToFile)
# GUI definition
self.tabs = OWGUI.tabWidget(self.space)
# GRAPH TAB
GraphTab = OWGUI.createTabPage(self.tabs, "Graph")
## display options
self.infoLabel = OWGUI.widgetLabel(OWGUI.widgetBox(GraphTab, "Info"), "No data on input.")
displayOptBox = OWGUI.widgetBox(GraphTab, "Display") #QVButtonGroup("Display", GraphTab)
displayOptButtons = ['Majority Class', 'Majority Class Probability', 'Target Class Probability', 'Number of Instances']
OWGUI.checkBox(displayOptBox, self, 'ShowSingleProfiles', 'Expression Profiles', tooltip='', callback=self.updateShowSingleProfiles)
OWGUI.checkBox(displayOptBox, self, 'ShowAverageProfile', 'Box Plot', tooltip='', callback=self.updateShowAverageProfile)
## class selection (classQLB)
self.classQVGB = OWGUI.widgetBox(GraphTab, "Classes") #QVGroupBox(GraphTab)
## self.classQVGB.setTitle("Classes")
self.classQLB = OWGUI.listBox(self.classQVGB, self, "SelectedClasses", "Classes", selectionMode=QListWidget.MultiSelection, callback=self.classSelectionChange) #QListBox(self.classQVGB)
## self.classQLB.setSelectionMode(QListBox.Multi)
self.unselectAllClassedQLB = OWGUI.button(self.classQVGB, self, "Unselect all", callback=self.SUAclassQLB) #QPushButton("(Un)Select All", self.classQVGB)
## self.connect(self.unselectAllClassedQLB, SIGNAL("clicked()"), self.SUAclassQLB)
## self.connect(self.classQLB, SIGNAL("selectionChanged()"), self.classSelectionChange)
## show single/average profile
## self.showAverageQLB = QPushButton("Box Plot", self.classQVGB)
## self.showAverageQLB.setToggleButton(1)
## self.showAverageQLB.setOn(self.ShowAverageProfile)
## self.showSingleQLB = QPushButton("Single Profiles", self.classQVGB)
## self.showSingleQLB.setToggleButton(1)
## self.showSingleQLB.setOn(self.ShowSingleProfiles)
## self.connect(self.showAverageQLB, SIGNAL("toggled(bool)"), self.updateShowAverageProfile)
## self.connect(self.showSingleQLB, SIGNAL("toggled(bool)"), self.updateShowSingleProfiles)
## self.tabs.insertTab(GraphTab, "Graph")
# SETTINGS TAB
SettingsTab = OWGUI.createTabPage(self.tabs, "Settings") #QVGroupBox(self)
self.profileLabelComboBox = OWGUI.comboBox(SettingsTab, self, 'profileLabel', 'Profile Labels', sendSelectedValue=True, valueType=str)
OWGUI.hSlider(SettingsTab, self, 'PointWidth', box='Point Width', minValue=0, maxValue=9, step=1, callback=self.updatePointWidth, ticks=1)
OWGUI.hSlider(SettingsTab, self, 'CurveWidth', box='Profile Width', minValue=1, maxValue=9, step=1, callback=self.updateCurveWidth, ticks=1)
OWGUI.hSlider(SettingsTab, self, 'AverageCurveWidth', box='Average Profile Width', minValue=1, maxValue=9, step=1, callback=self.updateAverageCurveWidth, ticks=1)
OWGUI.hSlider(SettingsTab, self, 'BoxPlotWidth', box='Box Plot Width', minValue=0, maxValue=9, step=1, callback=self.updateBoxPlotWidth, ticks=1)
OWGUI.checkBox(SettingsTab, self, 'graph.renderAntialiased', "Render antialiased", callback=self.graph.setCurveRenderHints)
## graph y scale
box = OWGUI.widgetBox(SettingsTab, "Threshold/ Values") #QVButtonGroup("Threshol/ Values", SettingsTab)
OWGUI.checkBox(box, self, 'CutEnabled', "Enabled", callback=self.setCutEnabled)
self.sliderCutLow = OWGUI.qwtHSlider(box, self, 'CutLow', label='Low:', labelWidth=33, minValue=-20, maxValue=0, step=0.1, precision=1, ticks=0, maxWidth=80, callback=self.updateYaxis)
self.sliderCutHigh = OWGUI.qwtHSlider(box, self, 'CutHigh', label='High:', labelWidth=33, minValue=0, maxValue=20, step=0.1, precision=1, ticks=0, maxWidth=80, callback=self.updateYaxis)
if not self.CutEnabled:
self.sliderCutLow.box.setDisabled(1)
self.sliderCutHigh.box.setDisabled(1)
## self.tabs.insertTab(SettingsTab, "Settings")
self.toolbarSelection = ZoomSelectToolbar(self, self.controlArea, self.graph, self.autoSendSelected, buttons=(ZoomSelectToolbar.IconZoom, ZoomSelectToolbar.IconPan, ZoomSelectToolbar.IconSelect, ZoomSelectToolbar.IconSpace,
ZoomSelectToolbar.IconRemoveLast, ZoomSelectToolbar.IconRemoveAll, ZoomSelectToolbar.IconSendSelection))
cb = OWGUI.checkBox(self.controlArea, self, "autoSendSelected", "Auto send on selection change")
OWGUI.setStopper(self, self.toolbarSelection.buttonSendSelections, cb, "selectionChangedFlag", self.commit)
# inputs
# data and graph temp variables
self.inputs = [("Examples", ExampleTable, self.data, Default + Multiple)]
self.outputs = [("Examples", ExampleTable, Default)]
# temp variables
self.MAdata = []
self.classColor = None
self.classBrighterColor = None
self.numberOfClasses = 0
self.classValues = []
self.ctrlPressed = False
self.attrIcons = self.createAttributeIconDict()
self.graph.canvas().setMouseTracking(1)
# self.zoomStack = []
## self.connect(self.graph,
## SIGNAL('plotMousePressed(const QMouseEvent&)'),
## self.onMousePressed)
## self.connect(self.graph,
## SIGNAL('plotMouseReleased(const QMouseEvent&)'),
## self.onMouseReleased)
self.resize(800,600)
def __init__(self, parent=None, signalManager=None, name="Gene selection"):
OWWidget.__init__(self, parent, signalManager, name, wantGraph=True, showSaveGraph=True)
self.inputs = [("Examples", ExampleTable, self.set_data)]
self.outputs = [("Example table with selected genes", ExampleTable), ("Example table with remaining genes", ExampleTable), ("Selected genes", ExampleTable)]
self.method_index = 0
self.genes_in_columns = False
self.compute_null = False
self.permutations_count = 10
self.auto_commit = False
self.selectNBest = 20
self.selectPValue = 0.01
self.data_changed_flag = False
self.add_scores_to_output = True
self.thresholds = {
"fold change": (0.5, 2.),
"log2 fold change": (-1, 1),
"t-test": (-2, 2),
"t-test p-value": (0.01, 0.01),
}
self.oneTailTestHi = oneTailTestHi = lambda array, low, hi: array >= hi
self.oneTailTestLow = oneTailTestLow = lambda array, low, hi: array <= low
self.twoTailTest = twoTailTest = lambda array, low, hi: (array >= hi) | (array <= low)
self.middleTest = middleTest = lambda array, low, hi: (array <= hi) | (array >= low)
self.histType = {oneTailTestHi:"hiTail", oneTailTestLow:"lowTail", twoTailTest:"twoTail", middleTest:"middle"}
# [(name, func, tail test, two sample test), ...]
self.score_methods = [("fold change", ExpressionSignificance_FoldChange, twoTailTest, True),
("log2 fold change", ExpressionSignificance_Log2FoldChange, twoTailTest, True),
("t-test", ExpressionSignificance_TTest_T, twoTailTest, True),
("t-test p-value", ExpressionSignificance_TTest_PValue, oneTailTestLow, True),
("anova", ExpressionSignificance_ANOVA_F, oneTailTestHi, False),
("anova p-value", ExpressionSignificance_ANOVA_PValue, oneTailTestLow, False),
("signal to noise ratio", ExpressionSignificance_SignalToNoise, twoTailTest, True),
("info gain", ExpressionSignificance_Info, oneTailTestHi, True),
("chi-square", ExpressionSignificance_ChiSquare, oneTailTestHi, True),
("mann-whitney", ExpressionSignigicance_MannWhitneyu_U, oneTailTestLow, True)]
boxHistogram = OWGUI.widgetBox(self.mainArea)
self.histogram = ScoreHist(self, boxHistogram)
boxHistogram.layout().addWidget(self.histogram)
self.histogram.show()
box = OWGUI.widgetBox(self.controlArea, "Info")
self.dataInfoLabel = OWGUI.widgetLabel(box, "\n\n")
self.dataInfoLabel.setWordWrap(True)
self.selectedInfoLabel = OWGUI.widgetLabel(box, "")
box1 = OWGUI.widgetBox(self.controlArea, "Scoring Method")
self.testRadioBox = OWGUI.comboBox(box1, self, "method_index",
items=[sm[0] for sm in self.score_methods],
callback=[self.on_scoring_method_changed, self.update_scores])
box = OWGUI.widgetBox(self.controlArea, "Target Labels")
self.label_selection_widget = LabelSelectionWidget(self)
self.label_selection_widget.setMaximumHeight(150)
box.layout().addWidget(self.label_selection_widget)
self.connect(self.label_selection_widget,
SIGNAL("selection_changed()"),
self.on_target_changed)
self.connect(self.label_selection_widget,
SIGNAL("label_activated(int)"),
self.on_label_activated)
self.genes_in_columns_check = OWGUI.checkBox(box, self, "genes_in_columns",
"Genes in columns",
callback=self.on_genes_in_columns_change)
box = OWGUI.widgetBox(self.controlArea, "Selection")
box.layout().setSpacing(0)
self.upperBoundarySpin = OWGUI.doubleSpin(box, self, "histogram.upperBoundary",
min=-1e6, max=1e6, step= 1e-6,
label="Upper threshold:",
callback=self.update_boundary,
callbackOnReturn=True)
self.lowerBoundarySpin = OWGUI.doubleSpin(box, self, "histogram.lowerBoundary",
min=-1e6, max=1e6, step= 1e-6,
label="Lower threshold:",
callback=self.update_boundary,
callbackOnReturn=True)
check = OWGUI.checkBox(box, self, "compute_null", "Compute null distribution",
callback=self.update_scores)
check.disables.append(OWGUI.spin(box, self, "permutations_count", min=1, max=10,
label="Permutations:", callback=self.update_scores,
callbackOnReturn=True))
box1 = OWGUI.widgetBox(box, orientation='horizontal')
check.disables.append(OWGUI.doubleSpin(box1, self, "selectPValue",
min=2e-7, max=1.0, step=1e-7,
label="P-value:"))
check.disables.append(OWGUI.button(box1, self, "Select", callback=self.select_p_best))
check.makeConsistent()
box1 = OWGUI.widgetBox(box, orientation='horizontal')
OWGUI.spin(box1, self, "selectNBest", 0, 10000, step=1, label="Best Ranked:")
OWGUI.button(box1, self, "Select", callback=self.select_n_best)
box = OWGUI.widgetBox(self.controlArea, "Output")
b = OWGUI.button(box, self, "&Commit", callback=self.commit)
cb = OWGUI.checkBox(box, self, "auto_commit", "Commit on change")
OWGUI.setStopper(self, b, cb, "data_changed_flag", self.commit)
OWGUI.checkBox(box, self, "add_scores_to_output", "Add gene scores to output",
callback=self.commit_if)
OWGUI.rubber(self.controlArea)
self.connect(self.graphButton, SIGNAL("clicked()"), self.histogram.saveToFile)
self.loadSettings()
self.data = None
self.discData = None
self.scoreCache = {}
self.nullDistCache = {}
self.cuts = {}
self.null_dist = []
self.targets = []
self.scores = {}
self.genes_in_columns = True
self.target_selections = None
self.on_scoring_method_changed()
self.resize(800, 600)
def __init__(self, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager, "Parallel Coordinates", True)
#add a graph widget
self.graph = OWParallelGraph(self, self.mainArea)
self.mainArea.layout().addWidget(self.graph)
self.showAllAttributes = 0
self.inputs = [("Data", ExampleTable, self.setData, Default),
("Data Subset", ExampleTable, self.setSubsetData),
("Features", AttributeList, self.setShownAttributes)]
self.outputs = [("Selected Data", ExampleTable),
("Other Data", ExampleTable),
("Features", AttributeList)]
#set default settings
self.data = None
self.subsetData = None
self.autoSendSelection = 1
self.attrDiscOrder = "Unordered"
self.attrContOrder = "Unordered"
self.projections = None
self.correlationDict = {}
self.middleLabels = "Correlations"
self.attributeSelectionList = None
self.toolbarSelection = 0
self.colorSettings = None
self.selectedSchemaIndex = 0
self.graph.jitterSize = 10
self.graph.showDistributions = 1
self.graph.showStatistics = 0
self.graph.showAttrValues = 1
self.graph.useSplines = 0
self.graph.enabledLegend = 1
#load settings
self.loadSettings()
#GUI
self.tabs = OWGUI.tabWidget(self.controlArea)
self.GeneralTab = OWGUI.createTabPage(self.tabs, "Main")
self.SettingsTab = OWGUI.createTabPage(self.tabs, "Settings")
self.createShowHiddenLists(self.GeneralTab, callback=self.updateGraph)
self.connect(self.shownAttribsLB, SIGNAL('itemDoubleClicked(QListWidgetItem*)'), self.flipAttribute)
self.optimizationDlg = ParallelOptimization(self, signalManager=self.signalManager)
self.optimizationDlgButton = OWGUI.button(self.GeneralTab, self, "Optimization Dialog",
callback=self.optimizationDlg.reshow, debuggingEnabled=0)
self.zoomSelectToolbar = OWToolbars.ZoomSelectToolbar(self, self.GeneralTab, self.graph, self.autoSendSelection,
buttons=(1, 2, 0, 7, 8))
self.connect(self.zoomSelectToolbar.buttonSendSelections, SIGNAL("clicked()"), self.sendSelections)
#connect controls to appropriate functions
self.connect(self.graphButton, SIGNAL("clicked()"), self.graph.saveToFile)
# ####################################
# SETTINGS functionality
box = OWGUI.widgetBox(self.SettingsTab, "Transparency")
OWGUI.hSlider(box, self, 'graph.alphaValue', label="Examples: ", minValue=0, maxValue=255, step=10,
callback=self.updateGraph, tooltip="Alpha value used for drawing example lines")
OWGUI.hSlider(box, self, 'graph.alphaValue2', label="Rest: ", minValue=0, maxValue=255, step=10,
callback=self.updateGraph, tooltip="Alpha value used to draw statistics, example subsets, ...")
box = OWGUI.widgetBox(self.SettingsTab, "Jittering Options")
OWGUI.comboBox(box, self, "graph.jitterSize", label='Jittering size (% of size): ', orientation='horizontal',
callback=self.setJitteringSize, items=self.jitterSizeNums, sendSelectedValue=1, valueType=float)
# visual settings
box = OWGUI.widgetBox(self.SettingsTab, "Visual Settings")
OWGUI.checkBox(box, self, 'graph.showAttrValues', 'Show attribute values', callback=self.updateGraph)
OWGUI.checkBox(box, self, 'graph.useAntialiasing', 'Use antialiasing', callback=self.updateGraph)
OWGUI.checkBox(box, self, 'graph.useSplines', 'Show splines', callback=self.updateGraph,
tooltip="Show lines using splines")
OWGUI.checkBox(box, self, 'graph.enabledLegend', 'Show legend', callback=self.updateGraph)
box = OWGUI.widgetBox(self.SettingsTab, "Axis Distance")
resizeColsBox = OWGUI.widgetBox(box, 0, "horizontal", 0)
OWGUI.label(resizeColsBox, self, "Increase/decrease distance: ")
OWGUI.toolButton(resizeColsBox, self, "+", callback=self.increaseAxesDistance,
tooltip="Increase the distance between the axes", width=30, height=20)
OWGUI.toolButton(resizeColsBox, self, "-", callback=self.decreaseAxesDistance,
tooltip="Decrease the distance between the axes", width=30, height=20)
OWGUI.rubber(resizeColsBox)
OWGUI.checkBox(box, self, "graph.autoUpdateAxes", "Auto scale X axis",
tooltip="Auto scale X axis to show all visualized attributes", callback=self.updateGraph)
box = OWGUI.widgetBox(self.SettingsTab, "Statistical Information")
OWGUI.comboBox(box, self, "graph.showStatistics", label="Statistics: ", orientation="horizontal", labelWidth=90,
items=["No statistics", "Means, deviations", "Median, quartiles"], callback=self.updateGraph,
sendSelectedValue=0, valueType=int)
OWGUI.comboBox(box, self, "middleLabels", label="Middle labels: ", orientation="horizontal", labelWidth=90,
items=["No labels", "Correlations", "VizRank"], callback=self.updateGraph,
tooltip="The information do you wish to view on top in the middle of coordinate axes",
sendSelectedValue=1, valueType=str)
OWGUI.checkBox(box, self, 'graph.showDistributions', 'Show distributions', callback=self.updateGraph,
tooltip="Show bars with distribution of class values (only for discrete attributes)")
box = OWGUI.widgetBox(self.SettingsTab, "Colors", orientation="horizontal")
OWGUI.button(box, self, "Set colors", self.setColors,
tooltip="Set the canvas background color and color palette for coloring continuous variables",
debuggingEnabled=0)
box = OWGUI.widgetBox(self.SettingsTab, "Auto Send Selected Data When...")
OWGUI.checkBox(box, self, 'autoSendSelection', 'Adding/Removing selection areas',
callback=self.selectionChanged,
tooltip="Send selected data whenever a selection area is added or removed")
OWGUI.checkBox(box, self, 'graph.sendSelectionOnUpdate', 'Moving/Resizing selection areas',
tooltip="Send selected data when a user moves or resizes an existing selection area")
self.graph.autoSendSelectionCallback = self.selectionChanged
self.SettingsTab.layout().addStretch(100)
self.icons = self.createAttributeIconDict()
dlg = self.createColorDialog()
self.graph.contPalette = dlg.getContinuousPalette("contPalette")
self.graph.discPalette = dlg.getDiscretePalette("discPalette")
self.graph.setCanvasBackground(dlg.getColor("Canvas"))
apply([self.zoomSelectToolbar.actionZooming, self.zoomSelectToolbar.actionRectangleSelection,
self.zoomSelectToolbar.actionPolygonSelection][self.toolbarSelection], [])
self.cbShowAllAttributes()
self.resize(900, 700)
def __init__(self, parent=None, signalManager = None, name='GSEA'):
OWWidget.__init__(self, parent, signalManager, name)
self.inputs = [("Examples", ExampleTable, self.setData)]
self.outputs = [("Examples with selected genes only", ExampleTable), ("Results", ExampleTable), ("Distance Matrix", orange.SymMatrix) ]
self.res = None
self.dm = None
self.name = 'GSEA'
self.minSubsetSize = 3
self.minSubsetSizeC = True
self.maxSubsetSize = 1000
self.maxSubsetSizeC = True
self.minSubsetPart = 10
self.minSubsetPartC = True
self.perms = 100
self.csgm = False
self.gsgo = False
self.gskegg = False
self.buildDistances = False
self.selectedPhenVar = 0
self.organismIndex = 0
self.atLeast = 3
self.permutationTypes = [("Phenotype", "p"),("Gene", "g") ]
self.ptype = 0
self.correlationTypes = [ ("Signal2Noise", "s2n") ]
self.ctype = 0
self.data = None
self.geneSets = {}
self.tabs = OWGUI.tabWidget(self.controlArea)
ca = OWGUI.createTabPage(self.tabs, "Basic")
box = OWGUI.widgetBox(ca, 'Organism')
#FROM KEGG WIDGET - organism selection
self.organismTaxids = []
self.organismComboBox = cb = OWGUI.comboBox(box, self, "organismIndex", items=[], debuggingEnabled=0) #changed
cb.setMaximumWidth(200)
#OWGUI.checkBox(box, self, "csgm", "Case sensitive gene matching")
box2 = OWGUI.widgetBox(ca, "Descriptors")
self.phenCombo = OWGUI.comboBox(box2, self, "selectedPhenVar", items=[], callback=self.phenComboChange, label="Phenotype:")
self.geneCombo = OWGUI.comboBox(box2, self, "selectedGeneVar", items=[], label = "Gene:")
self.allowComboChangeCallback = False
ma = self.mainArea
self.listView = QTreeWidget(ma)
ma.layout().addWidget(self.listView)
self.listView.setAllColumnsShowFocus(1)
self.listView.setColumnCount(9)
self.listView.setHeaderLabels(["Collection", "Geneset", "NES", "ES", "P-value", "FDR", "Size", "Matched Size", "Genes"])
self.listView.header().setStretchLastSection(True)
self.listView.header().setClickable(True)
self.listView.header().setSortIndicatorShown(True)
self.listView.setSortingEnabled(True)
#self.listView.header().setResizeMode(0, QHeaderView.Stretch)
self.listView.setSelectionMode(QAbstractItemView.NoSelection)
self.connect(self.listView, SIGNAL("itemSelectionChanged()"), self.newPathwaySelected)
OWGUI.separator(ca)
OWGUI.widgetLabel(ca, "Phenotype selection:")
self.psel = PhenotypesSelection(ca)
self.resize(600,50)
OWGUI.separator(ca)
OWGUI.checkBox(ca, self, "buildDistances", "Compute geneset distances")
self.btnApply = OWGUI.button(ca, self, "&Compute", callback = self.compute, disabled=0)
fileBox = OWGUI.widgetBox(ca, orientation='horizontal')
OWGUI.button(fileBox, self, "Load", callback = self.loadData, disabled=0, debuggingEnabled=0)
OWGUI.button(fileBox, self, "Save", callback = self.saveData, disabled=0, debuggingEnabled=0)
#ca.layout().addStretch(1)
ca = OWGUI.createTabPage(self.tabs, "Gene sets")
box = OWGUI.widgetBox(ca)
self.gridSel = []
self.geneSel = [] #FIXME temporary disabled - use the same as in new "David" widget
self.lbgs = OWGUI.listBox(box, self, "gridSel", "geneSel", selectionMode = QListWidget.MultiSelection)
OWGUI.button(box, self, "From &File", callback = self.addCollection, disabled=0, debuggingEnabled=0)
box = OWGUI.widgetBox(box, "Additional sources:")
OWGUI.checkBox(box, self, "gskegg", "KEGG pathways")
OWGUI.checkBox(box, self, "gsgo", "GO terms")
#ca.layout().addStretch(1)
ca = OWGUI.createTabPage(self.tabs, "Settings")
box = OWGUI.widgetBox(ca, 'Properties')
self.permTypeF = OWGUI.comboBoxWithCaption(box, self, "ptype", items=nth(self.permutationTypes, 0), \
tooltip="Permutation type.", label="Permute")
_ = OWGUI.spin(box, self, "perms", 50, 1000, orientation="horizontal", label="Times")
self.corTypeF = OWGUI.comboBoxWithCaption(box, self, "ctype", items=nth(self.correlationTypes, 0), \
tooltip="Correlation type.", label="Correlation")
box = OWGUI.widgetBox(ca, 'Subset Filtering')
_,_ = OWGUI.checkWithSpin(box, self, "Min. Subset Size", 1, 10000, "minSubsetSizeC", "minSubsetSize", "") #TODO check sizes
_,_ = OWGUI.checkWithSpin(box, self, "Max. Subset Size", 1, 10000, "maxSubsetSizeC", "maxSubsetSize", "")
_,_ = OWGUI.checkWithSpin(box, self, "Min. Subset Part (%)", 1, 100, "minSubsetPartC", "minSubsetPart", "")
box = OWGUI.widgetBox(ca, 'Gene Filtering')
_ = OWGUI.spin(box, self, "atLeast", 2, 10, label="Min. Values in Group")
ca.layout().addStretch(1)
self.addComment("Computation was not started.")
if sys.platform == "darwin":
self.loadFileName = os.path.expanduser("~/")
else:
self.loadFileName = "."
self.gridSels = []
self.loadSettings()
self.setBlocking(True)
QTimer.singleShot(0, self.UpdateOrganismComboBox)
def cleanInvalid(maxn):
"""
Removes invalid gene set selection
"""
notAllOk = True
while notAllOk:
self.gridSels = getattr(self, "gridSels")
notAllOk = False
for i,a in enumerate(self.gridSels):
if a >= maxn:
self.gridSels.pop(i)
notAllOk = True
break
cleanInvalid(len(self.geneSel))
self.gridSel = self.gridSels
self.gridSels = self.gridSel
def __init__(self, parent=None, signalManager=None, title="Gene Network"):
super(OWGeneNetwork, self).__init__(parent,
signalManager,
title,
wantMainArea=False,
resizingEnabled=False)
self.taxid = "9606"
self.gene_var_index = -1
self.use_attr_names = False
self.network_source = 1
self.include_neighborhood = True
self.autocommit = False
self.min_score = 0.9
self.loadSettings()
self.taxids = taxonomy.common_taxids()
self.current_taxid_index = self.taxids.index(self.taxid)
self.data = None
self.geneinfo = None
self.nettask = None
self._invalidated = False
box = OWGUI.widgetBox(self.controlArea, "Info")
self.info = OWGUI.widgetLabel(box, "No data on input\n")
box = OWGUI.widgetBox(self.controlArea, "Organism")
self.organism_cb = OWGUI.comboBox(box,
self,
"current_taxid_index",
items=map(taxonomy.name,
self.taxids),
callback=self._update_organism)
box = OWGUI.widgetBox(self.controlArea, "Genes")
self.genes_cb = OWGUI.comboBox(box,
self,
"gene_var_index",
callback=self._update_query_genes)
self.varmodel = OWItemModels.VariableListModel()
self.genes_cb.setModel(self.varmodel)
OWGUI.checkBox(box,
self,
"use_attr_names",
"Use attribute names",
callback=self._update_query_genes)
box = OWGUI.widgetBox(self.controlArea, "Network")
OWGUI.comboBox(box,
self,
"network_source",
items=[s.name for s in SOURCES],
callback=self._on_source_db_changed)
OWGUI.checkBox(box,
self,
"include_neighborhood",
"Include immediate gene neighbors",
callback=self.invalidate)
self.score_spin = OWGUI.doubleSpin(box,
self,
"min_score",
0.0,
1.0,
step=0.001,
label="Minimal edge score",
callback=self.invalidate)
self.score_spin.setEnabled(SOURCES[self.network_source].score_filter)
box = OWGUI.widgetBox(self.controlArea, "Commit")
OWGUI.button(box, self, "Commit", callback=self.commit, default=True)
self.executor = ThreadExecutor()
def __init__(self, parent=None, signalManager=None, title="Expression Profile Distances"):
OWWidget.__init__(self, parent, signalManager, title)
self.inputs = [("Example Table", ExampleTable, self.set_data)]
self.outputs = [("Distances", Orange.core.SymMatrix), ("Sorted Example Table", ExampleTable)]
self.distance_measure = 0
self.auto_commit = False
self.changed_flag = False
self.loadSettings()
########
# GUI
########
self.info_box = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Input", addSpace=True), "No data on input\n"
)
box = OWGUI.widgetBox(self.controlArea, "Separate By", addSpace=True)
self.separate_view = QListView()
self.separate_view.setSelectionMode(QListView.MultiSelection)
box.layout().addWidget(self.separate_view)
box = OWGUI.widgetBox(self.controlArea, "Sort By", addSpace=True)
self.relevant_view = QListView()
self.relevant_view.setSelectionMode(QListView.MultiSelection)
box.layout().addWidget(self.relevant_view)
self.distance_view = OWGUI.comboBox(
self.controlArea,
self,
"distance_measure",
box="Distance Measure",
items=[d[0] for d in self.DISTANCE_FUNCTIONS],
)
OWGUI.rubber(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Commit")
cb = OWGUI.checkBox(
box,
self,
"auto_commit",
"Commit on any change",
tooltip="Compute and send the distances on any change.",
callback=self.commit_if,
)
b = OWGUI.button(
box,
self,
"Commit",
tooltip="Compute the distances and send the output signals.",
callback=self.commit,
default=True,
)
OWGUI.setStopper(self, b, cb, "changed_flag", callback=self.commit)
self.groups_box = OWGUI.widgetBox(self.mainArea, "Groups")
self.groups_scroll_area = QScrollArea()
self.groups_box.layout().addWidget(self.groups_scroll_area)
self.data = None
self.partitions = []
self.matrix = None
self.split_groups = []
self._disable_updates = False
self.resize(800, 600)
def __init__(self, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager, "Parallel Coordinates",
True)
#add a graph widget
self.graph = OWParallelGraph(self, self.mainArea)
self.mainArea.layout().addWidget(self.graph)
self.showAllAttributes = 0
self.inputs = [("Data", ExampleTable, self.setData, Default),
("Data Subset", ExampleTable, self.setSubsetData),
("Features", AttributeList, self.setShownAttributes)]
self.outputs = [("Selected Data", ExampleTable),
("Other Data", ExampleTable),
("Features", AttributeList)]
#set default settings
self.data = None
self.subsetData = None
self.autoSendSelection = 1
self.attrDiscOrder = "Unordered"
self.attrContOrder = "Unordered"
self.projections = None
self.correlationDict = {}
self.middleLabels = "Correlations"
self.attributeSelectionList = None
self.toolbarSelection = 0
self.colorSettings = None
self.selectedSchemaIndex = 0
self.graph.jitterSize = 10
self.graph.showDistributions = 1
self.graph.showStatistics = 0
self.graph.showAttrValues = 1
self.graph.useSplines = 0
self.graph.enabledLegend = 1
#load settings
self.loadSettings()
#GUI
self.tabs = OWGUI.tabWidget(self.controlArea)
self.GeneralTab = OWGUI.createTabPage(self.tabs, "Main")
self.SettingsTab = OWGUI.createTabPage(self.tabs, "Settings")
self.createShowHiddenLists(self.GeneralTab, callback=self.updateGraph)
self.connect(self.shownAttribsLB,
SIGNAL('itemDoubleClicked(QListWidgetItem*)'),
self.flipAttribute)
self.optimizationDlg = ParallelOptimization(
self, signalManager=self.signalManager)
self.optimizationDlgButton = OWGUI.button(
self.GeneralTab,
self,
"Optimization Dialog",
callback=self.optimizationDlg.reshow,
debuggingEnabled=0)
self.zoomSelectToolbar = OWToolbars.ZoomSelectToolbar(
self,
self.GeneralTab,
self.graph,
self.autoSendSelection,
buttons=(1, 2, 0, 7, 8))
self.connect(self.zoomSelectToolbar.buttonSendSelections,
SIGNAL("clicked()"), self.sendSelections)
#connect controls to appropriate functions
self.connect(self.graphButton, SIGNAL("clicked()"),
self.graph.saveToFile)
# ####################################
# SETTINGS functionality
box = OWGUI.widgetBox(self.SettingsTab, "Transparency")
OWGUI.hSlider(box,
self,
'graph.alphaValue',
label="Examples: ",
minValue=0,
maxValue=255,
step=10,
callback=self.updateGraph,
tooltip="Alpha value used for drawing example lines")
OWGUI.hSlider(
box,
self,
'graph.alphaValue2',
label="Rest: ",
minValue=0,
maxValue=255,
step=10,
callback=self.updateGraph,
tooltip="Alpha value used to draw statistics, example subsets, ..."
)
box = OWGUI.widgetBox(self.SettingsTab, "Jittering Options")
OWGUI.comboBox(box,
self,
"graph.jitterSize",
label='Jittering size (% of size): ',
orientation='horizontal',
callback=self.setJitteringSize,
items=self.jitterSizeNums,
sendSelectedValue=1,
valueType=float)
# visual settings
box = OWGUI.widgetBox(self.SettingsTab, "Visual Settings")
OWGUI.checkBox(box,
self,
'graph.showAttrValues',
'Show attribute values',
callback=self.updateGraph)
OWGUI.checkBox(box,
self,
'graph.useAntialiasing',
'Use antialiasing',
callback=self.updateGraph)
OWGUI.checkBox(box,
self,
'graph.useSplines',
'Show splines',
callback=self.updateGraph,
tooltip="Show lines using splines")
OWGUI.checkBox(box,
self,
'graph.enabledLegend',
'Show legend',
callback=self.updateGraph)
box = OWGUI.widgetBox(self.SettingsTab, "Axis Distance")
resizeColsBox = OWGUI.widgetBox(box, 0, "horizontal", 0)
OWGUI.label(resizeColsBox, self, "Increase/decrease distance: ")
OWGUI.toolButton(resizeColsBox,
self,
"+",
callback=self.increaseAxesDistance,
tooltip="Increase the distance between the axes",
width=30,
height=20)
OWGUI.toolButton(resizeColsBox,
self,
"-",
callback=self.decreaseAxesDistance,
tooltip="Decrease the distance between the axes",
width=30,
height=20)
OWGUI.rubber(resizeColsBox)
OWGUI.checkBox(
box,
self,
"graph.autoUpdateAxes",
"Auto scale X axis",
tooltip="Auto scale X axis to show all visualized attributes",
callback=self.updateGraph)
box = OWGUI.widgetBox(self.SettingsTab, "Statistical Information")
OWGUI.comboBox(
box,
self,
"graph.showStatistics",
label="Statistics: ",
orientation="horizontal",
labelWidth=90,
items=["No statistics", "Means, deviations", "Median, quartiles"],
callback=self.updateGraph,
sendSelectedValue=0,
valueType=int)
OWGUI.comboBox(
box,
self,
"middleLabels",
label="Middle labels: ",
orientation="horizontal",
labelWidth=90,
items=["No labels", "Correlations", "VizRank"],
callback=self.updateGraph,
tooltip=
"The information do you wish to view on top in the middle of coordinate axes",
sendSelectedValue=1,
valueType=str)
OWGUI.checkBox(
box,
self,
'graph.showDistributions',
'Show distributions',
callback=self.updateGraph,
tooltip=
"Show bars with distribution of class values (only for discrete attributes)"
)
box = OWGUI.widgetBox(self.SettingsTab,
"Colors",
orientation="horizontal")
OWGUI.button(
box,
self,
"Set colors",
self.setColors,
tooltip=
"Set the canvas background color and color palette for coloring continuous variables",
debuggingEnabled=0)
box = OWGUI.widgetBox(self.SettingsTab,
"Auto Send Selected Data When...")
OWGUI.checkBox(
box,
self,
'autoSendSelection',
'Adding/Removing selection areas',
callback=self.selectionChanged,
tooltip=
"Send selected data whenever a selection area is added or removed")
OWGUI.checkBox(
box,
self,
'graph.sendSelectionOnUpdate',
'Moving/Resizing selection areas',
tooltip=
"Send selected data when a user moves or resizes an existing selection area"
)
self.graph.autoSendSelectionCallback = self.selectionChanged
self.SettingsTab.layout().addStretch(100)
self.icons = self.createAttributeIconDict()
dlg = self.createColorDialog()
self.graph.contPalette = dlg.getContinuousPalette("contPalette")
self.graph.discPalette = dlg.getDiscretePalette("discPalette")
self.graph.setCanvasBackground(dlg.getColor("Canvas"))
apply([
self.zoomSelectToolbar.actionZooming,
self.zoomSelectToolbar.actionRectangleSelection,
self.zoomSelectToolbar.actionPolygonSelection
][self.toolbarSelection], [])
self.cbShowAllAttributes()
self.resize(900, 700)
def __init__(self, parent=None, signalManager=None, title="Gene Atlas Tissue Expression"):
OWWidget.__init__(self, parent, signalManager, title)
self.inputs = [("Example Table", Orange.data.Table, self.set_data)]
self.outputs = [("Selected Genes", Orange.data.Table)]
self.selected_organism = "H**o sapiens"
self.selected_gene_attr = 0
self.genes_in_columns = False
self.selected_ef = 0
self.selected_ef_value = 0
self.loadSettings()
#####
# GUI
#####
box = OWGUI.widgetBox(self.controlArea, "Info", addSpace=True)
self.info_label = OWGUI.widgetLabel(box, "No data on input.\n")
box = OWGUI.widgetBox(self.controlArea, "Organism", addSpace=True)
cb = OWGUI.comboBox(box, self, "selected_organism",
items=self.ORGANISMS,
tooltip="Organism name",
callback=self.on_organism_change,
sendSelectedValue=True,
valueType=str
)
cb.setMaximumWidth(250)
box = OWGUI.widgetBox(self.controlArea, "Gene Attribute", addSpace=True)
self.gene_attr_cb = OWGUI.comboBox(box, self, "selected_gene_attr",
tooltip="Attribute (column) containing the gene names.",
callback=self.on_gene_attr_change,
)
self.gene_attr_cb.setMaximumWidth(250)
cb = OWGUI.checkBox(box, self, "genes_in_columns", "Use attribute names",
tooltip="Gene names in columns.",
callback=self.on_genes_change,)
cb.disables.append((-1, self.gene_attr_cb))
cb.makeConsistent()
box = OWGUI.widgetBox(self.controlArea, "Tissues", addSpace=True)
self.categories_cb = OWGUI.comboBox(box, self, "selected_ef",
box="Categories",
items=self.FACTORS,
tooltip="Experimental factor.",
callback=self.on_ef_change,
)
self.categories_cb.box.setFlat(True)
self.values_cb = OWGUI.comboBox(box, self, "selected_ef_value",
box="Values",
tooltip="Experimental factor value.",
callback=self.on_ef_value_change
)
self.values_cb.setMaximumWidth(250)
self.values_cb.box.setFlat(True)
box = OWGUI.widgetBox(self.controlArea, "Cache", addSpace=True)
OWGUI.button(box, self, "Clear cache",
callback=self.on_cache_clear,
tooltip="Clear Gene Atlas cache.")
OWGUI.rubber(self.controlArea)
OWGUI.button(self.controlArea, self, label="Commit",
callback=self.commit,
tooltip="Send selected genes")
self.report_view = QTreeView(self.mainArea)
self.report_view.setSelectionMode(QTreeView.ExtendedSelection)
self.report_view.setSortingEnabled(True)
self.report_view.setRootIsDecorated(False)
self.report_view.setAlternatingRowColors(True)
self.report_view.setEditTriggers(QTreeView.NoEditTriggers)
self.mainArea.layout().addWidget(self.report_view)
self.report_header = ["Gene symbol", "Up", "Down"]
model = QStandardItemModel()
model.setHorizontalHeaderLabels(self.report_header)
self.report_view.setModel(model)
self.data = None
self.candidate_vars = []
self.candidate_var_names = []
self.results = {}, {}, {}
self.ensembl_info = None
self.gene_matcher = obiGene.GMDirect()
self.loaded_matcher_taxid = None
self.unknown_genes = []
self.query_genes = []
# self.set_organism(self.selected_organism, update_results=False)
self.get_atlas_summary = obiGeneAtlas.get_atlas_summary
#Cached construct_matcher
@lru_cache(maxsize=3)
def my_cached_matcher(org):
return obiGeneAtlas.default_gene_matcher(org)
self.construct_matcher = my_cached_matcher
def __init__(self, parallelWidget, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager,
"Parallel Optimization Dialog", False)
self.setCaption("Parallel Optimization Dialog")
self.parallelWidget = parallelWidget
self.optimizationMeasure = 0
self.attributeCount = 5
self.numberOfAttributes = 6
self.fileName = ""
self.lastSaveDirName = os.getcwd() + "/"
self.fileBuffer = []
self.projections = []
self.allResults = []
self.canOptimize = 0
self.orderAllAttributes = 1 # do we wish to order all attributes or find just an interesting subset
self.worstVal = -1 # used in heuristics to stop the search in uninteresting parts of the graph
self.loadSettings()
self.measureBox = OWGUI.radioButtonsInBox(
self.controlArea,
self,
"optimizationMeasure", ["Correlation", "VizRank"],
box="Select optimization measure",
callback=self.updateGUI)
self.vizrankSettingsBox = OWGUI.widgetBox(self.controlArea,
"VizRank settings")
self.optimizeBox = OWGUI.widgetBox(self.controlArea, "Optimize")
self.manageBox = OWGUI.widgetBox(self.controlArea, "Manage results")
self.resultsBox = OWGUI.widgetBox(self.mainArea, "Results")
self.resultList = OWGUI.listBox(self.resultsBox, self)
self.resultList.setMinimumSize(200, 200)
self.connect(self.resultList, SIGNAL("itemSelectionChanged()"),
self.showSelectedAttributes)
# remove non-existing files
names = []
for i in range(len(self.fileBuffer) - 1, -1, -1):
(short, longName) = self.fileBuffer[i]
if not os.path.exists(longName):
self.fileBuffer.remove((short, longName))
else:
names.append(short)
names.append("(None)")
self.fileName = "(None)"
self.hbox1 = OWGUI.widgetBox(self.vizrankSettingsBox,
"VizRank projections file",
orientation="horizontal")
self.vizrankFileCombo = OWGUI.comboBox(
self.hbox1,
self,
"fileName",
items=names,
tooltip=
"File that contains information about interestingness of scatterplots\n"
"generated by VizRank method in scatterplot widget",
callback=self.changeProjectionFile,
sendSelectedValue=1,
valueType=str)
self.browseButton = OWGUI.button(self.hbox1,
self,
"...",
callback=self.loadProjections)
self.browseButton.setMaximumWidth(20)
self.resultsInfoBox = OWGUI.widgetBox(self.vizrankSettingsBox,
"VizRank parameters")
self.kNeighborsLabel = OWGUI.widgetLabel(self.resultsInfoBox,
"Number of neighbors (k):")
self.percentDataUsedLabel = OWGUI.widgetLabel(self.resultsInfoBox,
"Percent of data used:")
self.testingMethodLabel = OWGUI.widgetLabel(self.resultsInfoBox,
"Testing method used:")
self.qualityMeasureLabel = OWGUI.widgetLabel(self.resultsInfoBox,
"Quality measure used:")
self.allAttributesRadio = QRadioButton("Order all attributes",
self.optimizeBox)
self.optimizeBox.layout().addWidget(self.allAttributesRadio)
self.connect(self.allAttributesRadio, SIGNAL("clicked()"),
self.setAllAttributeRadio)
box = OWGUI.widgetBox(self.optimizeBox, orientation="horizontal")
self.subsetAttributeRadio = QRadioButton("Find subsets of", box)
box.layout().addWidget(self.subsetAttributeRadio)
self.connect(self.subsetAttributeRadio, SIGNAL("clicked()"),
self.setSubsetAttributeRadio)
self.subsetAttributeEdit = OWGUI.lineEdit(box,
self,
"numberOfAttributes",
valueType=int)
self.subsetAttributeEdit.setMaximumWidth(30)
OWGUI.widgetLabel(box, "attributes")
self.startOptimizationButton = OWGUI.button(
self.optimizeBox,
self,
"Start Optimization",
callback=self.startOptimization)
f = self.startOptimizationButton.font()
f.setBold(1)
self.startOptimizationButton.setFont(f)
self.stopOptimizationButton = OWGUI.button(
self.optimizeBox,
self,
"Stop Evaluation",
callback=self.stopOptimizationClick)
self.stopOptimizationButton.setFont(f)
self.stopOptimizationButton.hide()
self.connect(self.stopOptimizationButton, SIGNAL("clicked()"),
self.stopOptimizationClick)
self.clearButton = OWGUI.button(self.manageBox, self, "Clear Results",
self.clearResults)
self.loadButton = OWGUI.button(self.manageBox, self, "Load",
self.loadResults)
self.saveButton = OWGUI.button(self.manageBox, self, "Save",
self.saveResults)
self.closeButton = OWGUI.button(self.manageBox, self, "Close Dialog",
self.hide)
self.changeProjectionFile()
self.updateGUI()
if self.orderAllAttributes:
self.setAllAttributeRadio()
else:
self.setSubsetAttributeRadio()
def __init__(self, parent=None, signalManager=None, name="Normalize Expression Array"):
OWWidget.__init__(self, parent, signalManager, name, wantGraph=True)
self.inputs = [("Expression array", ExampleTable, self.setData)]
self.outputs = [("Normalized expression array", ExampleTable, Default), ("Filtered expression array", ExampleTable)]
self.selectedGroup = 0
self.selectedCenterMethod = 0
self.selectedMergeMethod = 0
self.zCutoff = 1.96
self.appendZScore = False
self.appendRIValues = False
self.autoCommit = False
self.loadSettings()
## GUI
self.infoBox = OWGUI.widgetLabel(OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"No data on input.")
box = OWGUI.widgetBox(self.controlArea, "Split by", addSpace=True)
self.groupCombo = OWGUI.comboBox(box, self, "selectedGroup",
callback=self.onGroupSelection
)
self.centerCombo = OWGUI.comboBox(self.controlArea, self, "selectedCenterMethod",
box="Center Fold-change Using",
items=[name for name, _ in self.CENTER_METHODS],
callback=self.onCenterMethodChange,
addSpace=True
)
self.mergeCombo = OWGUI.comboBox(self.controlArea, self, "selectedMergeMethod",
box="Merge Replicates",
items=[name for name, _ in self.MERGE_METHODS],
tooltip="Select the method for replicate merging",
callback=self.onMergeMethodChange,
addSpace=True
)
box = OWGUI.doubleSpin(self.controlArea, self, "zCutoff", 0.0, 3.0, 0.01,
box="Z-Score Cutoff",
callback=[self.replotMA, self.commitIf])
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Ouput")
OWGUI.checkBox(box, self, "appendZScore", "Append Z-Scores",
tooltip="Append calculated Z-Scores to output",
callback=self.commitIf
)
OWGUI.checkBox(box, self, "appendRIValues", "Append Log Ratio and Intensity values",
tooltip="Append calculated Log Ratio and Intensity values to output data",
callback=self.commitIf
)
cb = OWGUI.checkBox(box, self, "autoCommit", "Commit on change",
tooltip="Commit data on any change",
callback=self.commitIf
)
b = OWGUI.button(box, self, "Commit", callback=self.commit)
OWGUI.setStopper(self, b, cb, "changedFlag", callback=self.commit)
self.connect(self.graphButton, SIGNAL("clicked()"), self.saveGraph)
OWGUI.rubber(self.controlArea)
self.graph = OWGraph(self.mainArea)
self.graph.setAxisTitle(QwtPlot.xBottom, "Intensity: log<sub>10</sub>(R*G)")
self.graph.setAxisTitle(QwtPlot.yLeft, "Log ratio: log<sub>2</sub>(R/G)")
self.graph.showFilledSymbols = True
self.mainArea.layout().addWidget(self.graph)
self.groups = []
self.split_data = None, None
self.merged_splits = None, None
self.centered = None, None
self.changedFlag = False
self.data = None
self.resize(800, 600)
def __init__(self, parent=None, signalManager=None,
title="Molecule visualizer"):
super(OWMoleculeVisualizer, self).__init__(parent, signalManager, title)
self.colorFragments = 1
self.showFragments = 0
self.selectedFragment = ""
self.moleculeSmiles = []
self.fragmentSmiles = []
self.defFragmentSmiles = []
self.smiles_var = 0
self.moleculeTitleAttr = 0
self.moleculeTitleAttributeList = []
self.selectedMoleculeTitleAttrs = []
self.fragmentSmilesAttr = 0
self.imageSize = 200
self.numColumns = 4
self.commitOnChange = 0
## GUI
box = OWGUI.widgetBox(self.controlArea, "Info", addSpace=True)
self.infoLabel = OWGUI.label(box, self, "Chemicals:")
box = OWGUI.radioButtonsInBox(
self.controlArea, self, "showFragments",
["Show molecules", "Show fragments"], "Show",
callback=self.updateitems
)
self.showFragmentsRadioButton = box.buttons[-1]
self.markFragmentsCheckBox = OWGUI.checkBox(
box, self, "colorFragments", "Mark fragments",
callback=self._update
)
box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
self.moleculeSmilesCombo = OWGUI.comboBox(
self.controlArea, self, "smiles_var",
"Molecule SMILES Attribute",
callback=self.updateitems
)
self.moleculeSmilesCombo.box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum)
)
self.smiles_var_model = VariableListModel(parent=self)
self.moleculeSmilesCombo.setModel(self.smiles_var_model)
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Molecule Title Attributes",
addSpace=True)
self.title_var_view = QListView(
selectionMode=QListView.ExtendedSelection
)
self.title_var_model = VariableListModel(parent=self)
self.title_var_view.setModel(self.title_var_model)
self.title_var_view.selectionModel().selectionChanged.connect(
self._title_selection_changed
)
box.layout().addWidget(self.title_var_view)
OWGUI.separator(self.controlArea)
self.fragmentSmilesCombo = OWGUI.comboBox(
self.controlArea, self, "fragmentSmilesAttr",
"Fragment SMILES Attribute",
callback=self.updateFragmentsListBox
)
self.fragmentSmilesCombo.setModel(VariableListModel(parent=self))
self.fragmentSmilesCombo.box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum)
)
OWGUI.separator(self.controlArea)
box = OWGUI.spin(self.controlArea, self, "imageSize", 50, 500, 10,
box="Image Size", callback=self._image_size_changed)
box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Selection", addSpace=True)
OWGUI.checkBox(box, self, "commitOnChange", "Commit on change")
self.selectMarkedMoleculesButton = OWGUI.button(
box, self, "Select &matched molecules", self.select_marked
)
OWGUI.button(box, self, "&Commit", callback=self.commit, default=True)
OWGUI.separator(self.controlArea)
OWGUI.rubber(self.controlArea)
spliter = QSplitter(Qt.Vertical)
self.scrollArea = ScrollArea(spliter)
self.grid = GridWidget()
self.grid.selectionChanged.connect(self._on_selection_changed)
self.scrollArea.setWidget(self.grid)
self.scrollArea.setWidgetResizable(True)
self.mainArea.layout().addWidget(spliter)
if pybel:
self.listBox = QListWidget(spliter)
else:
self.listBox = QListWidget(None)
self.listBox.setHidden(True)
self.listBox.itemClicked.connect(self.fragmentSelection)
self.fragmentSmilesCombo.box.setDisabled(not pybel)
self.data = None
self.data_subset = []
self.fragment_data = None
self.resize(800, 600)
self.listBox.setMaximumHeight(150)
self.fragmentSmilesCombo.setDisabled(True)
self.selectMarkedMoleculesButton.setDisabled(True)
self.markFragmentsCheckBox.setDisabled(True)
self.showFragmentsRadioButton.setDisabled(True)
self.loadSettings()
if not pybel:
self.showFragments = 0
self.warning(10,
"Pybel module not installed. To view molecule fragments\n"
"please install openbabel python extension.")
self.__loop = None
def __init__(self,
parent=None,
signalManager=None,
title="Quality Control"):
OWWidget.__init__(self, parent, signalManager, title, wantGraph=True)
self.inputs = [("Experiment Data", Orange.data.Table, self.set_data)]
## Settings
self.selected_distance_index = 0
## Attributes
self.data = None
self.distances = None
self.groups = None
self.unique_pos = None
self.base_group_index = 0
## GUI
box = OWGUI.widgetBox(self.controlArea, "Info")
self.info_box = OWGUI.widgetLabel(box, "\n")
## Separate By box
box = OWGUI.widgetBox(self.controlArea, "Separate By")
self.split_by_model = PyListModel()
self.split_by_view = QListView()
self.split_by_view.setSelectionMode(QListView.ExtendedSelection)
self.split_by_view.setModel(self.split_by_model)
box.layout().addWidget(self.split_by_view)
self.connect(
self.split_by_view.selectionModel(),
SIGNAL("selectionChanged(QItemSelection, QItemSelection)"),
self.on_split_key_changed)
## Sort By box
box = OWGUI.widgetBox(self.controlArea, "Sort By")
self.sort_by_model = PyListModel()
self.sort_by_view = QListView()
self.sort_by_view.setSelectionMode(QListView.ExtendedSelection)
self.sort_by_view.setModel(self.sort_by_model)
box.layout().addWidget(self.sort_by_view)
self.connect(
self.sort_by_view.selectionModel(),
SIGNAL("selectionChanged(QItemSelection, QItemSelection)"),
self.on_sort_key_changed)
## Distance box
box = OWGUI.widgetBox(self.controlArea, "Distance Measure")
OWGUI.comboBox(box,
self,
"selected_distance_index",
items=[t[0] for t in self.DISTANCE_FUNCTIONS],
callback=self.on_distance_measure_changed)
self.connect(self.graphButton, SIGNAL("clicked()"), self.save_graph)
self.scene = QGraphicsScene()
self.scene_view = QualityGraphicsView(self.scene)
self.scene_view.setRenderHints(QPainter.Antialiasing)
self.scene_view.setAlignment(Qt.AlignLeft | Qt.AlignVCenter)
self.mainArea.layout().addWidget(self.scene_view)
self.connect(self.scene_view, SIGNAL("view_size_changed(QSize)"),
self.on_view_resize)
self._disable_updates = False
self._cached_distances = {}
self._base_index_hints = {}
self.main_widget = None
self.resize(800, 600)
def __init__(self,
parent=None,
signalManager=None,
title="Expression Profile Distances"):
OWWidget.__init__(self, parent, signalManager, title)
self.inputs = [("Example Table", ExampleTable, self.set_data)]
self.outputs = [("Distances", Orange.core.SymMatrix),
("Sorted Example Table", ExampleTable)]
self.distance_measure = 0
self.auto_commit = False
self.changed_flag = False
self.loadSettings()
########
# GUI
########
self.info_box = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Input", addSpace=True),
"No data on input\n")
box = OWGUI.widgetBox(self.controlArea, "Separate By", addSpace=True)
self.separate_view = QListView()
self.separate_view.setSelectionMode(QListView.MultiSelection)
box.layout().addWidget(self.separate_view)
box = OWGUI.widgetBox(self.controlArea, "Sort By", addSpace=True)
self.relevant_view = QListView()
self.relevant_view.setSelectionMode(QListView.MultiSelection)
box.layout().addWidget(self.relevant_view)
self.distance_view = OWGUI.comboBox(
self.controlArea,
self,
"distance_measure",
box="Distance Measure",
items=[d[0] for d in self.DISTANCE_FUNCTIONS])
OWGUI.rubber(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Commit")
cb = OWGUI.checkBox(
box,
self,
"auto_commit",
"Commit on any change",
tooltip="Compute and send the distances on any change.",
callback=self.commit_if)
b = OWGUI.button(
box,
self,
"Commit",
tooltip="Compute the distances and send the output signals.",
callback=self.commit,
default=True)
OWGUI.setStopper(self, b, cb, "changed_flag", callback=self.commit)
self.groups_box = OWGUI.widgetBox(self.mainArea, "Groups")
self.groups_scroll_area = QScrollArea()
self.groups_box.layout().addWidget(self.groups_scroll_area)
self.data = None
self.partitions = []
self.matrix = None
self.split_groups = []
self._disable_updates = False
self.resize(800, 600)
def __init__(self, parent=None, signalManager=None, title="Gene Network"):
super(OWGeneNetwork, self).__init__(
parent, signalManager, title, wantMainArea=False,
resizingEnabled=False
)
self.taxid = "9606"
self.gene_var_index = -1
self.use_attr_names = False
self.network_source = 1
self.include_neighborhood = True
self.autocommit = False
self.min_score = 0.9
self.loadSettings()
self.taxids = taxonomy.common_taxids()
self.current_taxid_index = self.taxids.index(self.taxid)
self.data = None
self.geneinfo = None
self.nettask = None
self._invalidated = False
box = OWGUI.widgetBox(self.controlArea, "Info")
self.info = OWGUI.widgetLabel(box, "No data on input\n")
box = OWGUI.widgetBox(self.controlArea, "Organism")
self.organism_cb = OWGUI.comboBox(
box, self, "current_taxid_index",
items=map(taxonomy.name, self.taxids),
callback=self._update_organism
)
box = OWGUI.widgetBox(self.controlArea, "Genes")
self.genes_cb = OWGUI.comboBox(
box, self, "gene_var_index", callback=self._update_query_genes
)
self.varmodel = OWItemModels.VariableListModel()
self.genes_cb.setModel(self.varmodel)
OWGUI.checkBox(
box, self, "use_attr_names",
"Use attribute names",
callback=self._update_query_genes
)
box = OWGUI.widgetBox(self.controlArea, "Network")
OWGUI.comboBox(
box, self, "network_source",
items=[s.name for s in SOURCES],
callback=self._on_source_db_changed
)
OWGUI.checkBox(
box, self, "include_neighborhood",
"Include immediate gene neighbors",
callback=self.invalidate
)
self.score_spin = OWGUI.doubleSpin(
box, self, "min_score", 0.0, 1.0, step=0.001,
label="Minimal edge score",
callback=self.invalidate
)
self.score_spin.setEnabled(SOURCES[self.network_source].score_filter)
box = OWGUI.widgetBox(self.controlArea, "Commit")
OWGUI.button(box, self, "Commit", callback=self.commit, default=True)
self.executor = ThreadExecutor()
def __init__(self, parent=None, signalManager=None):
# self.callbackDeposit = [] # deposit for OWGUI callback functions
OWWidget.__init__(self, parent, signalManager, 'Expression Profiles',
1)
#set default settings
self.ShowAverageProfile = 1
self.ShowSingleProfiles = 0
self.PointWidth = 2
self.CurveWidth = 1
self.AverageCurveWidth = 4
self.BoxPlotWidth = 2
self.SelectedClasses = []
self.Classes = []
self.autoSendSelected = 0
self.selectionChangedFlag = False
self.CutLow = 0
self.CutHigh = 0
self.CutEnabled = 0
self.profileLabel = None
#load settings
self.loadSettings()
# GUI
self.graph = profilesGraph(self, self.mainArea, "")
self.mainArea.layout().addWidget(self.graph)
self.graph.hide()
self.connect(self.graphButton, SIGNAL("clicked()"),
self.graph.saveToFile)
# GUI definition
self.tabs = OWGUI.tabWidget(self.space)
# GRAPH TAB
GraphTab = OWGUI.createTabPage(self.tabs, "Graph")
## display options
self.infoLabel = OWGUI.widgetLabel(OWGUI.widgetBox(GraphTab, "Info"),
"No data on input.")
displayOptBox = OWGUI.widgetBox(
GraphTab, "Display") #QVButtonGroup("Display", GraphTab)
displayOptButtons = [
'Majority Class', 'Majority Class Probability',
'Target Class Probability', 'Number of Instances'
]
OWGUI.checkBox(displayOptBox,
self,
'ShowSingleProfiles',
'Expression Profiles',
tooltip='',
callback=self.updateShowSingleProfiles)
OWGUI.checkBox(displayOptBox,
self,
'ShowAverageProfile',
'Box Plot',
tooltip='',
callback=self.updateShowAverageProfile)
## class selection (classQLB)
self.classQVGB = OWGUI.widgetBox(GraphTab,
"Classes") #QVGroupBox(GraphTab)
## self.classQVGB.setTitle("Classes")
self.classQLB = OWGUI.listBox(
self.classQVGB,
self,
"SelectedClasses",
"Classes",
selectionMode=QListWidget.MultiSelection,
callback=self.classSelectionChange) #QListBox(self.classQVGB)
## self.classQLB.setSelectionMode(QListBox.Multi)
self.unselectAllClassedQLB = OWGUI.button(
self.classQVGB, self, "Unselect all", callback=self.SUAclassQLB
) #QPushButton("(Un)Select All", self.classQVGB)
## self.connect(self.unselectAllClassedQLB, SIGNAL("clicked()"), self.SUAclassQLB)
## self.connect(self.classQLB, SIGNAL("selectionChanged()"), self.classSelectionChange)
## show single/average profile
## self.showAverageQLB = QPushButton("Box Plot", self.classQVGB)
## self.showAverageQLB.setToggleButton(1)
## self.showAverageQLB.setOn(self.ShowAverageProfile)
## self.showSingleQLB = QPushButton("Single Profiles", self.classQVGB)
## self.showSingleQLB.setToggleButton(1)
## self.showSingleQLB.setOn(self.ShowSingleProfiles)
## self.connect(self.showAverageQLB, SIGNAL("toggled(bool)"), self.updateShowAverageProfile)
## self.connect(self.showSingleQLB, SIGNAL("toggled(bool)"), self.updateShowSingleProfiles)
## self.tabs.insertTab(GraphTab, "Graph")
# SETTINGS TAB
SettingsTab = OWGUI.createTabPage(self.tabs,
"Settings") #QVGroupBox(self)
self.profileLabelComboBox = OWGUI.comboBox(SettingsTab,
self,
'profileLabel',
'Profile Labels',
sendSelectedValue=True,
valueType=str)
OWGUI.hSlider(SettingsTab,
self,
'PointWidth',
box='Point Width',
minValue=0,
maxValue=9,
step=1,
callback=self.updatePointWidth,
ticks=1)
OWGUI.hSlider(SettingsTab,
self,
'CurveWidth',
box='Profile Width',
minValue=1,
maxValue=9,
step=1,
callback=self.updateCurveWidth,
ticks=1)
OWGUI.hSlider(SettingsTab,
self,
'AverageCurveWidth',
box='Average Profile Width',
minValue=1,
maxValue=9,
step=1,
callback=self.updateAverageCurveWidth,
ticks=1)
OWGUI.hSlider(SettingsTab,
self,
'BoxPlotWidth',
box='Box Plot Width',
minValue=0,
maxValue=9,
step=1,
callback=self.updateBoxPlotWidth,
ticks=1)
OWGUI.checkBox(SettingsTab,
self,
'graph.renderAntialiased',
"Render antialiased",
callback=self.graph.setCurveRenderHints)
## graph y scale
box = OWGUI.widgetBox(
SettingsTab, "Threshold/ Values"
) #QVButtonGroup("Threshol/ Values", SettingsTab)
OWGUI.checkBox(box,
self,
'CutEnabled',
"Enabled",
callback=self.setCutEnabled)
self.sliderCutLow = OWGUI.qwtHSlider(box,
self,
'CutLow',
label='Low:',
labelWidth=33,
minValue=-20,
maxValue=0,
step=0.1,
precision=1,
ticks=0,
maxWidth=80,
callback=self.updateYaxis)
self.sliderCutHigh = OWGUI.qwtHSlider(box,
self,
'CutHigh',
label='High:',
labelWidth=33,
minValue=0,
maxValue=20,
step=0.1,
precision=1,
ticks=0,
maxWidth=80,
callback=self.updateYaxis)
if not self.CutEnabled:
self.sliderCutLow.box.setDisabled(1)
self.sliderCutHigh.box.setDisabled(1)
## self.tabs.insertTab(SettingsTab, "Settings")
self.toolbarSelection = ZoomSelectToolbar(
self,
self.controlArea,
self.graph,
self.autoSendSelected,
buttons=(ZoomSelectToolbar.IconZoom, ZoomSelectToolbar.IconPan,
ZoomSelectToolbar.IconSelect, ZoomSelectToolbar.IconSpace,
ZoomSelectToolbar.IconRemoveLast,
ZoomSelectToolbar.IconRemoveAll,
ZoomSelectToolbar.IconSendSelection))
cb = OWGUI.checkBox(self.controlArea, self, "autoSendSelected",
"Auto send on selection change")
OWGUI.setStopper(self, self.toolbarSelection.buttonSendSelections, cb,
"selectionChangedFlag", self.commit)
# inputs
# data and graph temp variables
self.inputs = [("Examples", ExampleTable, self.data,
Default + Multiple)]
self.outputs = [("Examples", ExampleTable, Default)]
# temp variables
self.MAdata = []
self.classColor = None
self.classBrighterColor = None
self.numberOfClasses = 0
self.classValues = []
self.ctrlPressed = False
self.attrIcons = self.createAttributeIconDict()
self.graph.canvas().setMouseTracking(1)
# self.zoomStack = []
## self.connect(self.graph,
## SIGNAL('plotMousePressed(const QMouseEvent&)'),
## self.onMousePressed)
## self.connect(self.graph,
## SIGNAL('plotMouseReleased(const QMouseEvent&)'),
## self.onMouseReleased)
self.resize(800, 600)
def __init__(self, parent=None, signalManager=None, name="KEGG Pathways"):
OWWidget.__init__(self, parent, signalManager, name, wantGraph=True)
self.inputs = [("Examples", Orange.data.Table, self.SetData),
("Reference", Orange.data.Table, self.SetRefData)]
self.outputs = [("Selected Examples", Orange.data.Table),
("Unselected Examples", Orange.data.Table)]
self.organismIndex = 0
self.geneAttrIndex = 0
self.autoCommit = False
self.autoResize = True
self.useReference = False
self.useAttrNames = 0
self.showOrthology = True
self.loadSettings()
self.organismCodes = []
self._changedFlag = False
self.controlArea.setMaximumWidth(250)
box = OWGUI.widgetBox(self.controlArea, "Info")
self.infoLabel = OWGUI.widgetLabel(box, "No data on input\n")
# Organism selection.
box = OWGUI.widgetBox(self.controlArea, "Organism")
self.organismComboBox = OWGUI.comboBox(
box, self, "organismIndex",
items=[],
callback=self.Update,
addSpace=True,
debuggingEnabled=0,
tooltip="Select the organism of the input genes")
# Selection of genes attribute
box = OWGUI.widgetBox(self.controlArea, "Gene attribute")
self.geneAttrCandidates = VariableListModel(parent=self)
self.geneAttrCombo = OWGUI.comboBox(
box, self, "geneAttrIndex", callback=self.Update)
self.geneAttrCombo.setModel(self.geneAttrCandidates)
OWGUI.checkBox(box, self, "useAttrNames",
"Use variable names",
disables=[(-1, self.geneAttrCombo)],
callback=self.Update)
self.geneAttrCombo.setDisabled(bool(self.useAttrNames))
OWGUI.separator(self.controlArea)
OWGUI.checkBox(self.controlArea, self, "useReference",
"From signal",
box="Reference",
callback=self.Update)
OWGUI.separator(self.controlArea)
OWGUI.checkBox(self.controlArea, self, "showOrthology",
"Show pathways in full orthology",
box="Orthology",
callback=self.UpdateListView)
OWGUI.checkBox(self.controlArea, self, "autoResize",
"Resize to fit",
box="Image",
callback=self.UpdatePathwayViewTransform)
box = OWGUI.widgetBox(self.controlArea, "Cache Control")
OWGUI.button(box, self, "Clear cache",
callback=self.ClearCache,
tooltip="Clear all locally cached KEGG data.")
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Selection")
cb = OWGUI.checkBox(box, self, "autoCommit", "Commit on update")
button = OWGUI.button(box, self, "Commit", callback=self.Commit,
default=True)
OWGUI.setStopper(self, button, cb, "_changedFlag", self.Commit)
OWGUI.rubber(self.controlArea)
spliter = QSplitter(Qt.Vertical, self.mainArea)
self.pathwayView = PathwayView(self, spliter)
self.pathwayView.scene().selectionChanged.connect(
self._onSelectionChanged
)
self.mainArea.layout().addWidget(spliter)
self.listView = QTreeWidget(spliter)
spliter.addWidget(self.listView)
self.listView.setAllColumnsShowFocus(1)
self.listView.setColumnCount(4)
self.listView.setHeaderLabels(["Pathway", "P value",
"Genes", "Reference"])
self.listView.setSelectionMode(QTreeWidget.SingleSelection)
self.listView.setSortingEnabled(True)
self.listView.setMaximumHeight(200)
self.connect(self.listView,
SIGNAL("itemSelectionChanged()"),
self.UpdatePathwayView)
self.connect(self.graphButton,
SIGNAL("clicked()"),
self.saveGraph)
select = QAction(
"Select All", self,
shortcut=QKeySequence.SelectAll
)
select.triggered.connect(self.selectAll)
self.addAction(select)
self.data = None
self.refData = None
self.resize(800, 600)
self.connect(self,
SIGNAL("widgetStateChanged(QString, int, QString)"),
self.onStateChange)
self.has_new_data = False
self.has_new_reference_set = False
self._executor = ThreadExecutor()
self.setEnabled(False)
self.setBlocking(True)
QTimer.singleShot(0, self._initialize)
self.infoLabel.setText("Fetching organism definitions\n")
def __init__(self,
parent=None,
signalManager=None,
name="Normalize Expression Array"):
OWWidget.__init__(self, parent, signalManager, name, wantGraph=True)
self.inputs = [("Expression array", ExampleTable, self.setData)]
self.outputs = [("Normalized expression array", ExampleTable, Default),
("Filtered expression array", ExampleTable)]
self.selectedGroup = 0
self.selectedCenterMethod = 0
self.selectedMergeMethod = 0
self.zCutoff = 1.96
self.appendZScore = False
self.appendRIValues = False
self.autoCommit = False
self.loadSettings()
## GUI
self.infoBox = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"No data on input.")
box = OWGUI.widgetBox(self.controlArea, "Split by", addSpace=True)
self.groupCombo = OWGUI.comboBox(box,
self,
"selectedGroup",
callback=self.onGroupSelection)
self.centerCombo = OWGUI.comboBox(
self.controlArea,
self,
"selectedCenterMethod",
box="Center Fold-change Using",
items=[name for name, _ in self.CENTER_METHODS],
callback=self.onCenterMethodChange,
addSpace=True)
self.mergeCombo = OWGUI.comboBox(
self.controlArea,
self,
"selectedMergeMethod",
box="Merge Replicates",
items=[name for name, _ in self.MERGE_METHODS],
tooltip="Select the method for replicate merging",
callback=self.onMergeMethodChange,
addSpace=True)
box = OWGUI.doubleSpin(self.controlArea,
self,
"zCutoff",
0.0,
3.0,
0.01,
box="Z-Score Cutoff",
callback=[self.replotMA, self.commitIf])
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Ouput")
OWGUI.checkBox(box,
self,
"appendZScore",
"Append Z-Scores",
tooltip="Append calculated Z-Scores to output",
callback=self.commitIf)
OWGUI.checkBox(
box,
self,
"appendRIValues",
"Append Log Ratio and Intensity values",
tooltip=
"Append calculated Log Ratio and Intensity values to output data",
callback=self.commitIf)
cb = OWGUI.checkBox(box,
self,
"autoCommit",
"Commit on change",
tooltip="Commit data on any change",
callback=self.commitIf)
b = OWGUI.button(box, self, "Commit", callback=self.commit)
OWGUI.setStopper(self, b, cb, "changedFlag", callback=self.commit)
self.connect(self.graphButton, SIGNAL("clicked()"), self.saveGraph)
OWGUI.rubber(self.controlArea)
self.graph = OWGraph(self.mainArea)
self.graph.setAxisTitle(QwtPlot.xBottom,
"Intensity: log<sub>10</sub>(R*G)")
self.graph.setAxisTitle(QwtPlot.yLeft,
"Log ratio: log<sub>2</sub>(R/G)")
self.graph.showFilledSymbols = True
self.mainArea.layout().addWidget(self.graph)
self.groups = []
self.split_data = None, None
self.merged_splits = None, None
self.centered = None, None
self.changedFlag = False
self.data = None
self.resize(800, 600)
def __init__(self, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager, "&Display Motifs", 0)
# set default settings
self.colorBy = None
self.pvalThresholdIndex = None
self.pvalThreshold = None
#load settings
self.loadSettings()
# GUI
self.graph = OWGraph(self.mainArea)
self.graph.setYRlabels(None)
self.graph.enableGridXB(0)
self.graph.enableGridYL(1)
self.graph.setAxisMaxMinor(QwtPlot.xBottom, 10)
self.graph.setAxisMaxMajor(QwtPlot.xBottom, 10)
self.graph.setAxisAutoScale(QwtPlot.xBottom)
self.graph.setAxisScale(QwtPlot.xBottom, -1020, 0, 0)
self.mainArea.layout().addWidget(self.graph)
# inputs
# data and graph temp variables
self.inputs = [("Examples", ExampleTable, self.cdata, Default),
("Genes", list, self.newGeneList, Default),
("Motifs", list, self.newMotifList, Default)]
self.data = None
self.motifLines = []
self.visibleValues = []
self.valueToCurve = {}
self.allGenes = [] ## genes displayed always in same order
self.geneList = [] ## selected genes
self.motifList = [] ## selected motifs
self.valuesPresentInData = []
self.clusterPostProbThreshold = 0
# GUI
self.selValues = OWGUI.widgetBox(self.controlArea, "Values")
self.selcolorBy = OWGUI.widgetBox(self.controlArea, "Color By")
self.colorByCombo = OWGUI.comboBox(self.selcolorBy,
self,
"colorBy",
items=[],
callback=self.colorByChanged)
self.pvalThresholdCombo = OWGUI.comboBox(
self.selValues,
self,
"pvalThresholdIndex",
items=[],
callback=self.pvalThresholdChanged)
self.valuesQLB = QListWidget(self.selValues)
self.valuesQLB.setSelectionMode(QListWidget.MultiSelection)
self.connect(self.valuesQLB, SIGNAL("itemSelectionChanged()"),
self.valuesSelectionChange)
self.selValues.layout().addWidget(self.valuesQLB)
self.unselectAllQLB = OWGUI.button(self.selValues,
self,
"Unselect all",
callback=self.unselAll)
def __init__(self,parent=None, signalManager = None):
OWWidget.__init__(self, parent, signalManager, "Nomogram", 1)
#self.setWFlags(Qt.WResizeNoErase | Qt.WRepaintNoErase) #this works like magic.. no flicker during repaint!
self.parent = parent
# self.setWFlags(self.getWFlags()+Qt.WStyle_Maximize)
self.callbackDeposit = [] # deposit for OWGUI callback functions
self.alignType = 0
self.contType = 0
self.yAxis = 0
self.probability = 0
self.verticalSpacing = 60
self.verticalSpacingContinuous = 100
self.diff_between_ordinal = 30
self.fontSize = 9
self.lineWidth = 1
self.histogram = 0
self.histogram_size = 10
self.data = None
self.cl = None
self.confidence_check = 0
self.confidence_percent = 95
self.sort_type = 0
self.loadSettings()
self.pointsName = ["Total", "Total"]
self.totalPointsName = ["Probability", "Probability"]
self.bnomogram = None
self.inputs=[("Classifier", orange.Classifier, self.classifier), ("Data", Orange.data.Table, self.data)]
self.TargetClassIndex = 0
self.targetCombo = OWGUI.comboBox(self.controlArea, self, "TargetClassIndex", " Target Class ", addSpace=True, tooltip='Select target (prediction) class in the model.', callback = self.setTarget)
self.alignRadio = OWGUI.radioButtonsInBox(self.controlArea, self, 'alignType', ['Align left', 'Align by zero influence'], box='Attribute placement',
tooltips=['Attributes in nomogram are left aligned', 'Attributes are not aligned, top scale represents true (normalized) regression coefficient value'],
addSpace=True,
callback=self.showNomogram)
self.verticalSpacingLabel = OWGUI.spin(self.alignRadio, self, 'verticalSpacing', 15, 200, label = 'Vertical spacing:', orientation = 0, tooltip='Define space (pixels) between adjacent attributes.', callback = self.showNomogram)
self.ContRadio = OWGUI.radioButtonsInBox(self.controlArea, self, 'contType', ['1D projection', '2D curve'], 'Continuous attributes',
tooltips=['Continuous attribute are presented on a single scale', 'Two dimensional space is used to present continuous attributes in nomogram.'],
addSpace=True,
callback=[lambda:self.verticalSpacingContLabel.setDisabled(not self.contType), self.showNomogram])
self.verticalSpacingContLabel = OWGUI.spin(OWGUI.indentedBox(self.ContRadio, sep=OWGUI.checkButtonOffsetHint(self.ContRadio.buttons[-1])), self, 'verticalSpacingContinuous', 15, 200, label = "Height", orientation=0, tooltip='Define space (pixels) between adjacent 2d presentation of attributes.', callback = self.showNomogram)
self.verticalSpacingContLabel.setDisabled(not self.contType)
self.yAxisRadio = OWGUI.radioButtonsInBox(self.controlArea, self, 'yAxis', ['Point scale', 'Log odds ratios'], 'Scale',
tooltips=['values are normalized on a 0-100 point scale','values on top axis show log-linear contribution of attribute to full model'],
addSpace=True,
callback=self.showNomogram)
layoutBox = OWGUI.widgetBox(self.controlArea, "Display", orientation=1, addSpace=True)
self.probabilityCheck = OWGUI.checkBox(layoutBox, self, 'probability', 'Show prediction', tooltip='', callback = self.setProbability)
self.CICheck, self.CILabel = OWGUI.checkWithSpin(layoutBox, self, 'Confidence intervals (%):', min=1, max=99, step = 1, checked='confidence_check', value='confidence_percent', checkCallback=self.showNomogram, spinCallback = self.showNomogram)
self.histogramCheck, self.histogramLabel = OWGUI.checkWithSpin(layoutBox, self, 'Show histogram, size', min=1, max=30, checked='histogram', value='histogram_size', step = 1, tooltip='-(TODO)-', checkCallback=self.showNomogram, spinCallback = self.showNomogram)
OWGUI.separator(layoutBox)
self.sortOptions = ["No sorting", "Absolute importance", "Positive influence", "Negative influence"]
self.sortBox = OWGUI.comboBox(layoutBox, self, "sort_type", label="Sort by ", items=self.sortOptions, callback = self.sortNomogram, orientation="horizontal")
OWGUI.rubber(self.controlArea)
self.connect(self.graphButton, SIGNAL("clicked()"), self.menuItemPrinter)
#add a graph widget
self.header = OWNomogramHeader(None, self.mainArea)
self.header.setFixedHeight(60)
self.header.setVerticalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.header.setHorizontalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.graph = OWNomogramGraph(self.bnomogram, self.mainArea)
self.graph.setMinimumWidth(200)
self.graph.setHorizontalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.footer = OWNomogramHeader(None, self.mainArea)
self.footer.setFixedHeight(60*2+10)
self.footer.setVerticalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.footer.setHorizontalScrollBarPolicy(Qt.ScrollBarAlwaysOff)
self.mainArea.layout().addWidget(self.header)
self.mainArea.layout().addWidget(self.graph)
self.mainArea.layout().addWidget(self.footer)
self.resize(700,500)
#self.repaint()
#self.update()
# mouse pressed flag
self.mousepr = False
def __init__(self,
parent=None,
signalManager=None,
title="Gene Atlas Tissue Expression"):
OWWidget.__init__(self, parent, signalManager, title)
self.inputs = [("Example Table", Orange.data.Table, self.set_data)]
self.outputs = [("Selected Genes", Orange.data.Table)]
self.selected_organism = "H**o sapiens"
self.selected_gene_attr = 0
self.genes_in_columns = False
self.selected_ef = 0
self.selected_ef_value = 0
self.loadSettings()
#####
# GUI
#####
box = OWGUI.widgetBox(self.controlArea, "Info", addSpace=True)
self.info_label = OWGUI.widgetLabel(box, "No data on input.\n")
box = OWGUI.widgetBox(self.controlArea, "Organism", addSpace=True)
cb = OWGUI.comboBox(box,
self,
"selected_organism",
items=self.ORGANISMS,
tooltip="Organism name",
callback=self.on_organism_change,
sendSelectedValue=True,
valueType=str)
cb.setMaximumWidth(250)
box = OWGUI.widgetBox(self.controlArea,
"Gene Attribute",
addSpace=True)
self.gene_attr_cb = OWGUI.comboBox(
box,
self,
"selected_gene_attr",
tooltip="Attribute (column) containing the gene names.",
callback=self.on_gene_attr_change,
)
self.gene_attr_cb.setMaximumWidth(250)
cb = OWGUI.checkBox(
box,
self,
"genes_in_columns",
"Use attribute names",
tooltip="Gene names in columns.",
callback=self.on_genes_change,
)
cb.disables.append((-1, self.gene_attr_cb))
cb.makeConsistent()
box = OWGUI.widgetBox(self.controlArea, "Tissues", addSpace=True)
self.categories_cb = OWGUI.comboBox(
box,
self,
"selected_ef",
box="Categories",
items=self.FACTORS,
tooltip="Experimental factor.",
callback=self.on_ef_change,
)
self.categories_cb.box.setFlat(True)
self.values_cb = OWGUI.comboBox(box,
self,
"selected_ef_value",
box="Values",
tooltip="Experimental factor value.",
callback=self.on_ef_value_change)
self.values_cb.setMaximumWidth(250)
self.values_cb.box.setFlat(True)
box = OWGUI.widgetBox(self.controlArea, "Cache", addSpace=True)
OWGUI.button(box,
self,
"Clear cache",
callback=self.on_cache_clear,
tooltip="Clear Gene Atlas cache.")
OWGUI.rubber(self.controlArea)
OWGUI.button(self.controlArea,
self,
label="Commit",
callback=self.commit,
tooltip="Send selected genes")
self.report_view = QTreeView(self.mainArea)
self.report_view.setSelectionMode(QTreeView.ExtendedSelection)
self.report_view.setSortingEnabled(True)
self.report_view.setRootIsDecorated(False)
self.report_view.setAlternatingRowColors(True)
self.report_view.setEditTriggers(QTreeView.NoEditTriggers)
self.mainArea.layout().addWidget(self.report_view)
self.report_header = ["Gene symbol", "Up", "Down"]
model = QStandardItemModel()
model.setHorizontalHeaderLabels(self.report_header)
self.report_view.setModel(model)
self.data = None
self.candidate_vars = []
self.candidate_var_names = []
self.results = {}, {}, {}
self.ensembl_info = None
self.gene_matcher = obiGene.GMDirect()
self.loaded_matcher_taxid = None
self.unknown_genes = []
self.query_genes = []
# self.set_organism(self.selected_organism, update_results=False)
self.get_atlas_summary = obiGeneAtlas.get_atlas_summary
#Cached construct_matcher
@lru_cache(maxsize=3)
def my_cached_matcher(org):
return obiGeneAtlas.default_gene_matcher(org)
self.construct_matcher = my_cached_matcher
def __init__(self, parent=None, signalManager=None, name="Gene Info"):
OWWidget.__init__(self, parent, signalManager, name)
self.inputs = [("Examples", Orange.data.Table, self.setData)]
self.outputs = [("Selected Examples", Orange.data.Table)]
self.organismIndex = 0
self.taxid = None
self.geneAttr = 0
self.useAttr = False
self.autoCommit = False
self.searchString = ""
self.selectionChangedFlag = False
self.useAltSource = 0
self.loadSettings()
self.__initialized = False
self.initfuture = None
self.itemsfuture = None
self.infoLabel = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"Initializing\n"
)
self.organisms = None
self.organismBox = OWGUI.widgetBox(
self.controlArea, "Organism", addSpace=True)
self.organismComboBox = OWGUI.comboBox(
self.organismBox, self, "organismIndex",
callback=self._onSelectedOrganismChanged,
debuggingEnabled=0)
# For now only support one alt source, with a checkbox
# In the future this can be extended to multiple selections
self.altSourceCheck = OWGUI.checkBox(self.organismBox, self,
"useAltSource", "Show information from dictyBase",
callback=self.onAltSourceChange,
# debuggingEnabled=0,
)
self.altSourceCheck.hide()
box = OWGUI.widgetBox(self.controlArea, "Gene names", addSpace=True)
self.geneAttrComboBox = OWGUI.comboBox(
box, self, "geneAttr",
"Gene atttibute", callback=self.updateInfoItems
)
OWGUI.checkBox(box, self, "useAttr", "Use attribute names",
callback=self.updateInfoItems,
disables=[(-1, self.geneAttrComboBox)])
self.geneAttrComboBox.setDisabled(bool(self.useAttr))
box = OWGUI.widgetBox(self.controlArea, "Commit", addSpace=True)
b = OWGUI.button(box, self, "Commit", callback=self.commit)
c = OWGUI.checkBox(box, self, "autoCommit", "Commit on change")
OWGUI.setStopper(self, b, c, "selectionChangedFlag",
callback=self.commit)
# A label for dictyExpress link
self.dictyExpressBox = OWGUI.widgetBox(
self.controlArea, "Dicty Express")
self.linkLabel = OWGUI.widgetLabel(self.dictyExpressBox, "")
self.linkLabel.setOpenExternalLinks(False)
self.connect(self.linkLabel, SIGNAL("linkActivated(QString)"),
self.onDictyExpressLink)
self.dictyExpressBox.hide()
OWGUI.rubber(self.controlArea)
OWGUI.lineEdit(self.mainArea, self, "searchString", "Filter",
callbackOnType=True, callback=self.searchUpdate)
self.treeWidget = QTreeView(self.mainArea)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSelectionMode(
QAbstractItemView.ExtendedSelection)
self.treeWidget.setItemDelegate(
LinkStyledItemDelegate(self.treeWidget))
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.viewport().setMouseTracking(True)
self.treeWidget.setSortingEnabled(True)
self.mainArea.layout().addWidget(self.treeWidget)
box = OWGUI.widgetBox(self.mainArea, "",
orientation="horizontal")
OWGUI.button(box, self, "Select Filtered",
callback=self.selectFiltered)
OWGUI.button(box, self, "Clear Selection",
callback=self.treeWidget.clearSelection)
self.resize(1000, 700)
self.geneinfo = []
self.cells = []
self.row2geneinfo = {}
self.data = None
# : (# input genes, # matches genes)
self.matchedInfo = 0, 0
self.selectionUpdateInProgress = False
self.setBlocking(True)
self.executor = ThreadExecutor(self)
self.progressBarInit()
task = Task(
function=partial(
taxonomy.ensure_downloaded,
callback=methodinvoke(self, "advance", ())
)
)
task.resultReady.connect(self.initialize)
task.exceptionReady.connect(self._onInitializeError)
self.initfuture = self.executor.submit(task)
def __init__(self, parent=None, signalManager=None,
title="Quality Control"):
OWWidget.__init__(self, parent, signalManager, title,
wantGraph=True)
self.inputs = [("Experiment Data", Orange.data.Table, self.set_data)]
## Settings
self.selected_distance_index = 0
## Attributes
self.data = None
self.distances = None
self.groups = None
self.unique_pos = None
self.base_group_index = 0
## GUI
box = OWGUI.widgetBox(self.controlArea, "Info")
self.info_box = OWGUI.widgetLabel(box, "\n")
## Separate By box
box = OWGUI.widgetBox(self.controlArea, "Separate By")
self.split_by_model = PyListModel()
self.split_by_view = QListView()
self.split_by_view.setSelectionMode(QListView.ExtendedSelection)
self.split_by_view.setModel(self.split_by_model)
box.layout().addWidget(self.split_by_view)
self.connect(self.split_by_view.selectionModel(),
SIGNAL("selectionChanged(QItemSelection, QItemSelection)"),
self.on_split_key_changed)
## Sort By box
box = OWGUI.widgetBox(self.controlArea, "Sort By")
self.sort_by_model = PyListModel()
self.sort_by_view = QListView()
self.sort_by_view.setSelectionMode(QListView.ExtendedSelection)
self.sort_by_view.setModel(self.sort_by_model)
box.layout().addWidget(self.sort_by_view)
self.connect(self.sort_by_view.selectionModel(),
SIGNAL("selectionChanged(QItemSelection, QItemSelection)"),
self.on_sort_key_changed)
## Distance box
box = OWGUI.widgetBox(self.controlArea, "Distance Measure")
OWGUI.comboBox(box, self, "selected_distance_index",
items=[t[0] for t in self.DISTANCE_FUNCTIONS],
callback=self.on_distance_measure_changed)
self.connect(self.graphButton,
SIGNAL("clicked()"),
self.save_graph)
self.scene = QGraphicsScene()
self.scene_view = QualityGraphicsView(self.scene)
self.scene_view.setRenderHints(QPainter.Antialiasing)
self.scene_view.setAlignment(Qt.AlignLeft | Qt.AlignVCenter)
self.mainArea.layout().addWidget(self.scene_view)
self.connect(self.scene_view,
SIGNAL("view_size_changed(QSize)"),
self.on_view_resize)
self._disable_updates = False
self._cached_distances = {}
self._base_index_hints = {}
self.main_widget = None
self.resize(800, 600)
def __init__(self, parent=None, signalManager=None, name="Gene selection"):
OWWidget.__init__(self,
parent,
signalManager,
name,
wantGraph=True,
showSaveGraph=True)
self.inputs = [("Examples", ExampleTable, self.set_data)]
self.outputs = [("Example table with selected genes", ExampleTable),
("Example table with remaining genes", ExampleTable),
("Selected genes", ExampleTable)]
self.method_index = 0
self.genes_in_columns = False
self.compute_null = False
self.permutations_count = 10
self.auto_commit = False
self.selectNBest = 20
self.selectPValue = 0.01
self.data_changed_flag = False
self.add_scores_to_output = True
self.thresholds = {
"fold change": (0.5, 2.),
"log2 fold change": (-1, 1),
"t-test": (-2, 2),
"t-test p-value": (0.01, 0.01),
}
self.oneTailTestHi = oneTailTestHi = lambda array, low, hi: array >= hi
self.oneTailTestLow = oneTailTestLow = lambda array, low, hi: array <= low
self.twoTailTest = twoTailTest = lambda array, low, hi: (
array >= hi) | (array <= low)
self.middleTest = middleTest = lambda array, low, hi: (array <= hi) | (
array >= low)
self.histType = {
oneTailTestHi: "hiTail",
oneTailTestLow: "lowTail",
twoTailTest: "twoTail",
middleTest: "middle"
}
# [(name, func, tail test, two sample test), ...]
self.score_methods = [
("fold change", ExpressionSignificance_FoldChange, twoTailTest,
True),
("log2 fold change", ExpressionSignificance_Log2FoldChange,
twoTailTest, True),
("t-test", ExpressionSignificance_TTest_T, twoTailTest, True),
("t-test p-value", ExpressionSignificance_TTest_PValue,
oneTailTestLow, True),
("anova", ExpressionSignificance_ANOVA_F, oneTailTestHi, False),
("anova p-value", ExpressionSignificance_ANOVA_PValue,
oneTailTestLow, False),
("signal to noise ratio", ExpressionSignificance_SignalToNoise,
twoTailTest, True),
("info gain", ExpressionSignificance_Info, oneTailTestHi, True),
("chi-square", ExpressionSignificance_ChiSquare, oneTailTestHi,
True),
("mann-whitney", ExpressionSignigicance_MannWhitneyu_U,
oneTailTestLow, True)
]
boxHistogram = OWGUI.widgetBox(self.mainArea)
self.histogram = ScoreHist(self, boxHistogram)
boxHistogram.layout().addWidget(self.histogram)
self.histogram.show()
box = OWGUI.widgetBox(self.controlArea, "Info")
self.dataInfoLabel = OWGUI.widgetLabel(box, "\n\n")
self.dataInfoLabel.setWordWrap(True)
self.selectedInfoLabel = OWGUI.widgetLabel(box, "")
box1 = OWGUI.widgetBox(self.controlArea, "Scoring Method")
self.testRadioBox = OWGUI.comboBox(
box1,
self,
"method_index",
items=[sm[0] for sm in self.score_methods],
callback=[self.on_scoring_method_changed, self.update_scores])
box = OWGUI.widgetBox(self.controlArea, "Target Labels")
self.label_selection_widget = LabelSelectionWidget(self)
self.label_selection_widget.setMaximumHeight(150)
box.layout().addWidget(self.label_selection_widget)
self.connect(self.label_selection_widget,
SIGNAL("selection_changed()"), self.on_target_changed)
self.connect(self.label_selection_widget,
SIGNAL("label_activated(int)"), self.on_label_activated)
self.genes_in_columns_check = OWGUI.checkBox(
box,
self,
"genes_in_columns",
"Genes in columns",
callback=self.on_genes_in_columns_change)
box = OWGUI.widgetBox(self.controlArea, "Selection")
box.layout().setSpacing(0)
self.upperBoundarySpin = OWGUI.doubleSpin(
box,
self,
"histogram.upperBoundary",
min=-1e6,
max=1e6,
step=1e-6,
label="Upper threshold:",
callback=self.update_boundary,
callbackOnReturn=True)
self.lowerBoundarySpin = OWGUI.doubleSpin(
box,
self,
"histogram.lowerBoundary",
min=-1e6,
max=1e6,
step=1e-6,
label="Lower threshold:",
callback=self.update_boundary,
callbackOnReturn=True)
check = OWGUI.checkBox(box,
self,
"compute_null",
"Compute null distribution",
callback=self.update_scores)
check.disables.append(
OWGUI.spin(box,
self,
"permutations_count",
min=1,
max=10,
label="Permutations:",
callback=self.update_scores,
callbackOnReturn=True))
box1 = OWGUI.widgetBox(box, orientation='horizontal')
check.disables.append(
OWGUI.doubleSpin(box1,
self,
"selectPValue",
min=2e-7,
max=1.0,
step=1e-7,
label="P-value:"))
check.disables.append(
OWGUI.button(box1, self, "Select", callback=self.select_p_best))
check.makeConsistent()
box1 = OWGUI.widgetBox(box, orientation='horizontal')
OWGUI.spin(box1,
self,
"selectNBest",
0,
10000,
step=1,
label="Best Ranked:")
OWGUI.button(box1, self, "Select", callback=self.select_n_best)
box = OWGUI.widgetBox(self.controlArea, "Output")
b = OWGUI.button(box, self, "&Commit", callback=self.commit)
cb = OWGUI.checkBox(box, self, "auto_commit", "Commit on change")
OWGUI.setStopper(self, b, cb, "data_changed_flag", self.commit)
OWGUI.checkBox(box,
self,
"add_scores_to_output",
"Add gene scores to output",
callback=self.commit_if)
OWGUI.rubber(self.controlArea)
self.connect(self.graphButton, SIGNAL("clicked()"),
self.histogram.saveToFile)
self.loadSettings()
self.data = None
self.discData = None
self.scoreCache = {}
self.nullDistCache = {}
self.cuts = {}
self.null_dist = []
self.targets = []
self.scores = {}
self.genes_in_columns = True
self.target_selections = None
self.on_scoring_method_changed()
self.resize(800, 600)
def __init__(self,
parent=None,
signalManager=None,
title="Molecule visualizer"):
super(OWMoleculeVisualizer, self).__init__(parent, signalManager,
title)
self.colorFragments = 1
self.showFragments = 0
self.selectedFragment = ""
self.moleculeSmiles = []
self.fragmentSmiles = []
self.defFragmentSmiles = []
self.smiles_var = 0
self.moleculeTitleAttr = 0
self.moleculeTitleAttributeList = []
self.selectedMoleculeTitleAttrs = []
self.fragmentSmilesAttr = 0
self.imageSize = 200
self.numColumns = 4
self.commitOnChange = 0
## GUI
box = OWGUI.widgetBox(self.controlArea, "Info", addSpace=True)
self.infoLabel = OWGUI.label(box, self, "Chemicals:")
box = OWGUI.radioButtonsInBox(self.controlArea,
self,
"showFragments",
["Show molecules", "Show fragments"],
"Show",
callback=self.updateitems)
self.showFragmentsRadioButton = box.buttons[-1]
self.markFragmentsCheckBox = OWGUI.checkBox(box,
self,
"colorFragments",
"Mark fragments",
callback=self._update)
box.setSizePolicy(QSizePolicy(QSizePolicy.Minimum,
QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
self.moleculeSmilesCombo = OWGUI.comboBox(self.controlArea,
self,
"smiles_var",
"Molecule SMILES Attribute",
callback=self.updateitems)
self.moleculeSmilesCombo.box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum))
self.smiles_var_model = VariableListModel(parent=self)
self.moleculeSmilesCombo.setModel(self.smiles_var_model)
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea,
"Molecule Title Attributes",
addSpace=True)
self.title_var_view = QListView(
selectionMode=QListView.ExtendedSelection)
self.title_var_model = VariableListModel(parent=self)
self.title_var_view.setModel(self.title_var_model)
self.title_var_view.selectionModel().selectionChanged.connect(
self._title_selection_changed)
box.layout().addWidget(self.title_var_view)
OWGUI.separator(self.controlArea)
self.fragmentSmilesCombo = OWGUI.comboBox(
self.controlArea,
self,
"fragmentSmilesAttr",
"Fragment SMILES Attribute",
callback=self.updateFragmentsListBox)
self.fragmentSmilesCombo.setModel(VariableListModel(parent=self))
self.fragmentSmilesCombo.box.setSizePolicy(
QSizePolicy(QSizePolicy.Minimum, QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
box = OWGUI.spin(self.controlArea,
self,
"imageSize",
50,
500,
10,
box="Image Size",
callback=self._image_size_changed)
box.setSizePolicy(QSizePolicy(QSizePolicy.Minimum,
QSizePolicy.Maximum))
OWGUI.separator(self.controlArea)
box = OWGUI.widgetBox(self.controlArea, "Selection", addSpace=True)
OWGUI.checkBox(box, self, "commitOnChange", "Commit on change")
self.selectMarkedMoleculesButton = OWGUI.button(
box, self, "Select &matched molecules", self.select_marked)
OWGUI.button(box, self, "&Commit", callback=self.commit, default=True)
OWGUI.separator(self.controlArea)
OWGUI.rubber(self.controlArea)
spliter = QSplitter(Qt.Vertical)
self.scrollArea = ScrollArea(spliter)
self.grid = GridWidget()
self.grid.selectionChanged.connect(self._on_selection_changed)
self.scrollArea.setWidget(self.grid)
self.scrollArea.setWidgetResizable(True)
self.mainArea.layout().addWidget(spliter)
if pybel:
self.listBox = QListWidget(spliter)
else:
self.listBox = QListWidget(None)
self.listBox.setHidden(True)
self.listBox.itemClicked.connect(self.fragmentSelection)
self.fragmentSmilesCombo.box.setDisabled(not pybel)
self.data = None
self.data_subset = []
self.fragment_data = None
self.resize(800, 600)
self.listBox.setMaximumHeight(150)
self.fragmentSmilesCombo.setDisabled(True)
self.selectMarkedMoleculesButton.setDisabled(True)
self.markFragmentsCheckBox.setDisabled(True)
self.showFragmentsRadioButton.setDisabled(True)
self.loadSettings()
if not pybel:
self.showFragments = 0
self.warning(
10, "Pybel module not installed. To view molecule fragments\n"
"please install openbabel python extension.")
self.__loop = None
def __init__(self, parallelWidget, parent=None, signalManager=None):
OWWidget.__init__(self, parent, signalManager, "Parallel Optimization Dialog", False)
self.setCaption("Parallel Optimization Dialog")
self.parallelWidget = parallelWidget
self.optimizationMeasure = 0
self.attributeCount = 5
self.numberOfAttributes = 6
self.fileName = ""
self.lastSaveDirName = os.getcwd() + "/"
self.fileBuffer = []
self.projections = []
self.allResults = []
self.canOptimize = 0
self.orderAllAttributes = 1 # do we wish to order all attributes or find just an interesting subset
self.worstVal = -1 # used in heuristics to stop the search in uninteresting parts of the graph
self.loadSettings()
self.measureBox = OWGUI.radioButtonsInBox(self.controlArea, self, "optimizationMeasure",
["Correlation", "VizRank"], box="Select optimization measure",
callback=self.updateGUI)
self.vizrankSettingsBox = OWGUI.widgetBox(self.controlArea, "VizRank settings")
self.optimizeBox = OWGUI.widgetBox(self.controlArea, "Optimize")
self.manageBox = OWGUI.widgetBox(self.controlArea, "Manage results")
self.resultsBox = OWGUI.widgetBox(self.mainArea, "Results")
self.resultList = OWGUI.listBox(self.resultsBox, self)
self.resultList.setMinimumSize(200, 200)
self.connect(self.resultList, SIGNAL("itemSelectionChanged()"), self.showSelectedAttributes)
# remove non-existing files
names = []
for i in range(len(self.fileBuffer) - 1, -1, -1):
(short, longName) = self.fileBuffer[i]
if not os.path.exists(longName):
self.fileBuffer.remove((short, longName))
else:
names.append(short)
names.append("(None)")
self.fileName = "(None)"
self.hbox1 = OWGUI.widgetBox(self.vizrankSettingsBox, "VizRank projections file", orientation="horizontal")
self.vizrankFileCombo = OWGUI.comboBox(self.hbox1, self, "fileName", items=names,
tooltip="File that contains information about interestingness of scatterplots\n"
"generated by VizRank method in scatterplot widget",
callback=self.changeProjectionFile, sendSelectedValue=1, valueType=str)
self.browseButton = OWGUI.button(self.hbox1, self, "...", callback=self.loadProjections)
self.browseButton.setMaximumWidth(20)
self.resultsInfoBox = OWGUI.widgetBox(self.vizrankSettingsBox, "VizRank parameters")
self.kNeighborsLabel = OWGUI.widgetLabel(self.resultsInfoBox, "Number of neighbors (k):")
self.percentDataUsedLabel = OWGUI.widgetLabel(self.resultsInfoBox, "Percent of data used:")
self.testingMethodLabel = OWGUI.widgetLabel(self.resultsInfoBox, "Testing method used:")
self.qualityMeasureLabel = OWGUI.widgetLabel(self.resultsInfoBox, "Quality measure used:")
self.allAttributesRadio = QRadioButton("Order all attributes", self.optimizeBox)
self.optimizeBox.layout().addWidget(self.allAttributesRadio)
self.connect(self.allAttributesRadio, SIGNAL("clicked()"), self.setAllAttributeRadio)
box = OWGUI.widgetBox(self.optimizeBox, orientation="horizontal")
self.subsetAttributeRadio = QRadioButton("Find subsets of", box)
box.layout().addWidget(self.subsetAttributeRadio)
self.connect(self.subsetAttributeRadio, SIGNAL("clicked()"), self.setSubsetAttributeRadio)
self.subsetAttributeEdit = OWGUI.lineEdit(box, self, "numberOfAttributes", valueType=int)
self.subsetAttributeEdit.setMaximumWidth(30)
OWGUI.widgetLabel(box, "attributes")
self.startOptimizationButton = OWGUI.button(self.optimizeBox, self, "Start Optimization",
callback=self.startOptimization)
f = self.startOptimizationButton.font()
f.setBold(1)
self.startOptimizationButton.setFont(f)
self.stopOptimizationButton = OWGUI.button(self.optimizeBox, self, "Stop Evaluation",
callback=self.stopOptimizationClick)
self.stopOptimizationButton.setFont(f)
self.stopOptimizationButton.hide()
self.connect(self.stopOptimizationButton, SIGNAL("clicked()"), self.stopOptimizationClick)
self.clearButton = OWGUI.button(self.manageBox, self, "Clear Results", self.clearResults)
self.loadButton = OWGUI.button(self.manageBox, self, "Load", self.loadResults)
self.saveButton = OWGUI.button(self.manageBox, self, "Save", self.saveResults)
self.closeButton = OWGUI.button(self.manageBox, self, "Close Dialog", self.hide)
self.changeProjectionFile()
self.updateGUI()
if self.orderAllAttributes:
self.setAllAttributeRadio()
else:
self.setSubsetAttributeRadio()
