def evaluate(model: AdapNet, dl: DataLoader, mode, batch_size=2): """ Evaluates the model, uses IoU as the metric :param model: The model to evaluate :param dl: The DataLoader of the model :param mode: The evaluations mode, one of "test" or "validation" :param batch_size: The batch size for the evaluation :return: """ model.eval() if mode == "test": set = dl.test_set else: set = dl.validation_set reps = len(set) // batch_size cm = ConfusionMatrix(dl.num_labels) iou_cur = IoU(cm) with torch.no_grad(): for _ in range(reps): m1, m2, gt = dl.sample_batch(batch_size, mode=mode) _, _, res = model(m1, m2) res = torch.softmax(res, dim=1) cm.update((res, gt)) iou_score = iou_cur.compute() print("Evaluation of " + mode + " set") print("mIoU: " + str(iou_score.mean().item())) print("IoU: " + str(iou_score)) return iou_score
class UNetTrainer(Trainer): def __init__(self, training_config, model_trainers: List[ModelTrainer], train_data_loader: DataLoader, valid_data_loader: DataLoader, test_data_loader: DataLoader, reconstruction_datasets: List[Dataset], input_reconstructor: ImageReconstructor, segmentation_reconstructor: ImageReconstructor, augmented_input_reconstructor: ImageReconstructor, gt_reconstructor: ImageReconstructor, run_config: RunConfiguration, dataset_config: dict, save_folder: str): super(UNetTrainer, self).__init__("UNetTrainer", train_data_loader, valid_data_loader, test_data_loader, model_trainers, run_config) self._training_config = training_config self._run_config = run_config self._dataset_configs = dataset_config self._slicer = ImageSlicer() self._seg_slicer = SegmentationSlicer() self._label_mapper = LabelMapper() self._reconstruction_datasets = reconstruction_datasets self._input_reconstructor = input_reconstructor self._gt_reconstructor = gt_reconstructor self._segmentation_reconstructor = segmentation_reconstructor self._augmented_input_reconstructor = augmented_input_reconstructor self._num_datasets = len(list(dataset_config.keys())) self._class_hausdorff_distance_gauge = AverageGauge() self._mean_hausdorff_distance_gauge = AverageGauge() self._per_dataset_hausdorff_distance_gauge = AverageGauge() self._iSEG_dice_gauge = AverageGauge() self._MRBrainS_dice_gauge = AverageGauge() self._ABIDE_dice_gauge = AverageGauge() self._iSEG_hausdorff_gauge = AverageGauge() self._MRBrainS_hausdorff_gauge = AverageGauge() self._ABIDE_hausdorff_gauge = AverageGauge() self._valid_dice_gauge = AverageGauge() self._class_dice_gauge_on_patches = AverageGauge() self._class_dice_gauge_on_reconstructed_images = AverageGauge() self._class_dice_gauge_on_reconstructed_iseg_images = AverageGauge() self._class_dice_gauge_on_reconstructed_mrbrains_images = AverageGauge() self._class_dice_gauge_on_reconstructed_abide_images = AverageGauge() self._hausdorff_distance_gauge_on_reconstructed_iseg_images = AverageGauge() self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images = AverageGauge() self._hausdorff_distance_gauge_on_reconstructed_abide_images = AverageGauge() self._general_confusion_matrix_gauge = ConfusionMatrix(num_classes=4) self._iSEG_confusion_matrix_gauge = ConfusionMatrix(num_classes=4) self._MRBrainS_confusion_matrix_gauge = ConfusionMatrix(num_classes=4) self._ABIDE_confusion_matrix_gauge = ConfusionMatrix(num_classes=4) self._previous_mean_dice = 0.0 self._previous_per_dataset_table = "" self._start_time = time.time() self._sampler = Sampler(1.0) self._save_folder = save_folder self._is_sliced = True if isinstance(self._reconstruction_datasets[0], SliceDataset) else False print("Total number of parameters: {}".format(sum(p.numel() for p in self._model_trainers[0].parameters()))) def _train_s(self, S: ModelTrainer, inputs, target, backward=True): S.zero_grad() target_ohe = to_onehot(torch.squeeze(target, dim=1).long(), num_classes=4) target = torch.squeeze(target, dim=1).long() seg_pred = torch.nn.functional.softmax(S.forward(inputs), dim=1) loss_S = S.compute_loss("DiceLoss", seg_pred, target_ohe) S.update_train_loss("DiceLoss", loss_S.mean()) metrics = S.compute_metrics(seg_pred, target) metrics["Dice"] = metrics["Dice"].mean() metrics["IoU"] = metrics["IoU"].mean() S.update_train_metrics(metrics) if backward: loss_S.mean().backward() S.step() return seg_pred, loss_S def _valid_s(self, S: ModelTrainer, inputs, target): target_ohe = to_onehot(torch.squeeze(target, dim=1).long(), num_classes=4) target = torch.squeeze(target, dim=1).long() seg_pred = torch.nn.functional.softmax(S.forward(inputs), dim=1) loss_S = S.compute_loss("DiceLoss", seg_pred, target_ohe) S.update_valid_loss("DiceLoss", loss_S.mean()) metrics = S.compute_metrics(seg_pred, target) metrics["Dice"] = metrics["Dice"].mean() metrics["IoU"] = metrics["IoU"].mean() S.update_valid_metrics(metrics) return seg_pred, loss_S def _test_s(self, S: ModelTrainer, inputs, target, metric_gauge: AverageGauge): target_ohe = to_onehot(torch.squeeze(target, dim=1).long(), num_classes=4) target = torch.squeeze(target, dim=1).long() seg_pred = torch.nn.functional.softmax(S.forward(inputs), dim=1) loss_S = S.compute_loss("DiceLoss", seg_pred, target_ohe) S.update_test_loss("DiceLoss", loss_S.mean()) metrics = S.compute_metrics(seg_pred, target) metric_gauge.update(np.array(metrics["Dice"])) metrics["Dice"] = metrics["Dice"].mean() metrics["IoU"] = metrics["IoU"].mean() S.update_test_metrics(metrics) return seg_pred, loss_S def train_step(self, inputs, target): seg_pred, _ = self._train_s(self._model_trainers[0], inputs[AUGMENTED_INPUTS], target[IMAGE_TARGET]) if self.current_train_step % 500 == 0: self._update_image_plots(self.phase, inputs[AUGMENTED_INPUTS].cpu().detach(), seg_pred.cpu().detach(), target[IMAGE_TARGET].cpu().detach(), target[DATASET_ID].cpu().detach()) def validate_step(self, inputs, target): seg_pred, _ = self._valid_s(self._model_trainers[0], inputs[AUGMENTED_INPUTS], target[IMAGE_TARGET]) if self.current_valid_step % 100 == 0: self._update_image_plots(self.phase, inputs[AUGMENTED_INPUTS].cpu().detach(), seg_pred.cpu().detach(), target[IMAGE_TARGET].cpu().detach(), target[DATASET_ID].cpu().detach()) def test_step(self, inputs, target): inputs, target = self._sampler(inputs, target) target = target[AUGMENTED_TARGETS] seg_pred, _ = self._test_s(self._model_trainers[0], inputs[AUGMENTED_INPUTS], target[IMAGE_TARGET], self._class_dice_gauge_on_patches) if self.current_test_step % 100 == 0: self._update_histograms(inputs[AUGMENTED_INPUTS], target) self._update_image_plots(self.phase, inputs[AUGMENTED_INPUTS].cpu().detach(), seg_pred.cpu().detach(), target[IMAGE_TARGET].cpu().detach(), target[DATASET_ID].cpu().detach()) if seg_pred[torch.where(target[DATASET_ID] == ISEG_ID)].shape[0] != 0: self._iSEG_dice_gauge.update(np.array(self._model_trainers[0].compute_metrics( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == ISEG_ID)], dim=1), torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == ISEG_ID)], dim=1).long())["Dice"].numpy())) self._iSEG_hausdorff_gauge.update(mean_hausdorff_distance( to_onehot( torch.argmax( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == ISEG_ID)], dim=1), dim=1), num_classes=4), to_onehot( torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == ISEG_ID)], dim=1).long(), num_classes=4))[-3:]) self._iSEG_confusion_matrix_gauge.update(( to_onehot( torch.argmax( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == ISEG_ID)], dim=1), dim=1, keepdim=False), num_classes=4), torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == ISEG_ID)].long(), dim=1))) else: self._iSEG_dice_gauge.update(np.zeros((3,))) self._iSEG_hausdorff_gauge.update(np.zeros((3,))) if seg_pred[torch.where(target[DATASET_ID] == MRBRAINS_ID)].shape[0] != 0: self._MRBrainS_dice_gauge.update(np.array(self._model_trainers[0].compute_metrics( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == MRBRAINS_ID)], dim=1), torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == MRBRAINS_ID)], dim=1).long())["Dice"].numpy())) self._MRBrainS_hausdorff_gauge.update(mean_hausdorff_distance( to_onehot( torch.argmax( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == MRBRAINS_ID)], dim=1), dim=1), num_classes=4), to_onehot( torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == MRBRAINS_ID)], dim=1).long(), num_classes=4))[-3:]) self._MRBrainS_confusion_matrix_gauge.update(( to_onehot( torch.argmax( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == MRBRAINS_ID)], dim=1), dim=1, keepdim=False), num_classes=4), torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == MRBRAINS_ID)].long(), dim=1))) else: self._MRBrainS_dice_gauge.update(np.zeros((3,))) self._MRBrainS_hausdorff_gauge.update(np.zeros((3,))) if seg_pred[torch.where(target[DATASET_ID] == ABIDE_ID)].shape[0] != 0: self._ABIDE_dice_gauge.update(np.array(self._model_trainers[0].compute_metrics( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == ABIDE_ID)], dim=1), torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == ABIDE_ID)], dim=1).long())["Dice"].numpy())) self._ABIDE_hausdorff_gauge.update(mean_hausdorff_distance( to_onehot( torch.argmax( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == ABIDE_ID)], dim=1), dim=1), num_classes=4), to_onehot( torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == ABIDE_ID)], dim=1).long(), num_classes=4))[-3:]) self._ABIDE_confusion_matrix_gauge.update(( to_onehot( torch.argmax( torch.nn.functional.softmax(seg_pred[torch.where(target[DATASET_ID] == ABIDE_ID)], dim=1), dim=1, keepdim=False), num_classes=4), torch.squeeze(target[IMAGE_TARGET][torch.where(target[DATASET_ID] == ABIDE_ID)].long(), dim=1))) self._class_hausdorff_distance_gauge.update( mean_hausdorff_distance( to_onehot(torch.argmax(torch.nn.functional.softmax(seg_pred, dim=1), dim=1), num_classes=4), to_onehot(torch.squeeze(target[IMAGE_TARGET], dim=1).long(), num_classes=4))[-3:]) self._general_confusion_matrix_gauge.update(( to_onehot(torch.argmax(torch.nn.functional.softmax(seg_pred, dim=1), dim=1, keepdim=False), num_classes=4), torch.squeeze(target[IMAGE_TARGET].long(), dim=1))) def scheduler_step(self): self._model_trainers[0].scheduler_step() def on_epoch_begin(self): self._class_hausdorff_distance_gauge.reset() self._mean_hausdorff_distance_gauge.reset() self._iSEG_dice_gauge.reset() self._MRBrainS_dice_gauge.reset() self._ABIDE_dice_gauge.reset() self._iSEG_hausdorff_gauge.reset() self._MRBrainS_hausdorff_gauge.reset() self._ABIDE_hausdorff_gauge.reset() self._class_dice_gauge_on_patches.reset() self._general_confusion_matrix_gauge.reset() self._iSEG_confusion_matrix_gauge.reset() self._MRBrainS_confusion_matrix_gauge.reset() self._ABIDE_confusion_matrix_gauge.reset() def on_test_epoch_end(self): if self.epoch % 10 == 0: self._per_dataset_hausdorff_distance_gauge.reset() self._class_dice_gauge_on_reconstructed_iseg_images.reset() self._class_dice_gauge_on_reconstructed_mrbrains_images.reset() self._class_dice_gauge_on_reconstructed_abide_images.reset() self._hausdorff_distance_gauge_on_reconstructed_iseg_images.reset() self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.reset() self._hausdorff_distance_gauge_on_reconstructed_abide_images.reset() img_input = self._input_reconstructor.reconstruct_from_patches_3d() img_gt = self._gt_reconstructor.reconstruct_from_patches_3d() img_seg = self._segmentation_reconstructor.reconstruct_from_patches_3d() save_rebuilt_image(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_input, "Input") save_rebuilt_image(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_gt, "Ground_Truth") save_rebuilt_image(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_seg, "Segmented") if self._training_config.build_augmented_images: img_augmented_input = self._augmented_input_reconstructor.reconstruct_from_patches_3d() img_augmented_normalized = self._augmented_normalized_reconstructor.reconstruct_from_patches_3d() save_augmented_rebuilt_images(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_augmented_input, img_augmented_normalized) mean_mhd = [] for dataset in self._dataset_configs.keys(): self.custom_variables[ "Reconstructed Segmented {} Image".format(dataset)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, np.expand_dims(img_seg[dataset], 0), 160).squeeze(0) self.custom_variables[ "Reconstructed Ground Truth {} Image".format(dataset)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, np.expand_dims(img_gt[dataset], 0), 160).squeeze(0) self.custom_variables[ "Reconstructed Input {} Image".format(dataset)] = self._slicer.get_slice( SliceType.AXIAL, np.expand_dims(img_input[dataset], 0), 160) if self._training_config.build_augmented_images: self.custom_variables[ "Reconstructed Augmented Input {} Image".format(dataset)] = self._slicer.get_slice( SliceType.AXIAL, np.expand_dims(np.expand_dims(img_augmented_input[dataset], 0), 0), 160) self.custom_variables[ "Reconstructed Augmented {} After Normalization".format( dataset)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, np.expand_dims(np.expand_dims(img_augmented_normalized[dataset], 0), 0), 160).squeeze(0) else: self.custom_variables["Reconstructed Augmented Input {} Image".format( dataset)] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Initial Noise {} Image".format( dataset)] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Augmented {} After Normalization".format( dataset)] = np.zeros((224, 192)) mean_mhd.append(mean_hausdorff_distance( to_onehot(torch.tensor(img_gt[dataset], dtype=torch.long), num_classes=4), to_onehot(torch.tensor(img_seg[dataset], dtype=torch.long), num_classes=4))[-3:].mean()) metric = self._model_trainers[0].compute_metrics( to_onehot(torch.tensor(img_seg[dataset]).unsqueeze(0).long(), num_classes=4), torch.tensor(img_gt[dataset]).unsqueeze(0).long()) self._class_dice_gauge_on_reconstructed_images.update(np.array(metric["Dice"])) self._per_dataset_hausdorff_distance_gauge.update(np.array(mean_mhd)) if "iSEG" in img_seg: metric = self._model_trainers[0].compute_metrics( to_onehot(torch.tensor(img_seg["iSEG"]).unsqueeze(0).long(), num_classes=4), torch.tensor(img_gt["iSEG"]).unsqueeze(0).long()) self._class_dice_gauge_on_reconstructed_iseg_images.update(np.array(metric["Dice"])) self._hausdorff_distance_gauge_on_reconstructed_iseg_images.update(mean_hausdorff_distance( to_onehot(torch.tensor(img_gt["iSEG"], dtype=torch.long), num_classes=4), to_onehot(torch.tensor(img_seg["iSEG"], dtype=torch.long), num_classes=4))[-3:]) else: self._class_dice_gauge_on_reconstructed_iseg_images.update(np.array([0.0, 0.0, 0.0])) self._hausdorff_distance_gauge_on_reconstructed_iseg_images.update(np.array([0.0, 0.0, 0.0])) if "MRBrainS" in img_seg: metric = self._model_trainers[0].compute_metrics( to_onehot(torch.tensor(img_seg["MRBrainS"]).unsqueeze(0).long(), num_classes=4), torch.tensor(img_gt["MRBrainS"]).unsqueeze(0).long()) self._class_dice_gauge_on_reconstructed_mrbrains_images.update(np.array(metric["Dice"])) self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.update(mean_hausdorff_distance( to_onehot(torch.tensor(img_gt["MRBrainS"], dtype=torch.long), num_classes=4), to_onehot(torch.tensor(img_seg["MRBrainS"], dtype=torch.long), num_classes=4))[-3:]) else: self._class_dice_gauge_on_reconstructed_mrbrains_images.update(np.array([0.0, 0.0, 0.0])) self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.update(np.array([0.0, 0.0, 0.0])) if "ABIDE" in img_seg: metric = self._model_trainers[0].compute_metrics( to_onehot(torch.tensor(img_seg["ABIDE"]).unsqueeze(0).long(), num_classes=4), torch.tensor(img_gt["ABIDE"]).unsqueeze(0).long()) self._class_dice_gauge_on_reconstructed_abide_images.update(np.array(metric["Dice"])) self._hausdorff_distance_gauge_on_reconstructed_abide_images.update(mean_hausdorff_distance( to_onehot(torch.tensor(img_gt["ABIDE"], dtype=torch.long), num_classes=4), to_onehot(torch.tensor(img_seg["ABIDE"], dtype=torch.long), num_classes=4))[-3:]) else: self._class_dice_gauge_on_reconstructed_abide_images.update(np.array([0.0, 0.0, 0.0])) self._hausdorff_distance_gauge_on_reconstructed_abide_images.update(np.array([0.0, 0.0, 0.0])) if "ABIDE" not in self._dataset_configs.keys(): self.custom_variables["Reconstructed Segmented ABIDE Image"] = np.zeros((224, 192)) self.custom_variables["Reconstructed Ground Truth ABIDE Image"] = np.zeros((224, 192)) self.custom_variables["Reconstructed Input ABIDE Image"] = np.zeros((224, 192)) if "iSEG" not in self._dataset_configs.keys(): self.custom_variables["Reconstructed Segmented iSEG Image"] = np.zeros((224, 192)) self.custom_variables["Reconstructed Ground Truth iSEG Image"] = np.zeros((224, 192)) self.custom_variables["Reconstructed Input iSEG Image"] = np.zeros((224, 192)) if "MRBrainS" not in self._dataset_configs.keys(): self.custom_variables["Reconstructed Segmented MRBrainS Image"] = np.zeros((224, 192)) self.custom_variables["Reconstructed Ground Truth MRBrainS Image"] = np.zeros((224, 192)) self.custom_variables["Reconstructed Input MRBrainS Image"] = np.zeros((224, 192)) self.custom_variables["Runtime"] = to_html_time(timedelta(seconds=time.time() - self._start_time)) if self._general_confusion_matrix_gauge._num_examples != 0: self.custom_variables["Confusion Matrix"] = np.array( np.fliplr(self._general_confusion_matrix_gauge.compute().cpu().detach().numpy())) else: self.custom_variables["Confusion Matrix"] = np.zeros((4, 4)) if self._iSEG_confusion_matrix_gauge._num_examples != 0: self.custom_variables["iSEG Confusion Matrix"] = np.array( np.fliplr(self._iSEG_confusion_matrix_gauge.compute().cpu().detach().numpy())) else: self.custom_variables["iSEG Confusion Matrix"] = np.zeros((4, 4)) if self._MRBrainS_confusion_matrix_gauge._num_examples != 0: self.custom_variables["MRBrainS Confusion Matrix"] = np.array( np.fliplr(self._MRBrainS_confusion_matrix_gauge.compute().cpu().detach().numpy())) else: self.custom_variables["MRBrainS Confusion Matrix"] = np.zeros((4, 4)) if self._ABIDE_confusion_matrix_gauge._num_examples != 0: self.custom_variables["ABIDE Confusion Matrix"] = np.array( np.fliplr(self._ABIDE_confusion_matrix_gauge.compute().cpu().detach().numpy())) else: self.custom_variables["ABIDE Confusion Matrix"] = np.zeros((4, 4)) self.custom_variables["Metric Table"] = to_html(["CSF", "Grey Matter", "White Matter"], ["DSC", "HD"], [ self._class_dice_gauge_on_patches.compute() if self._class_dice_gauge_on_patches.has_been_updated() else np.array( [0.0, 0.0, 0.0]), self._class_hausdorff_distance_gauge.compute() if self._class_hausdorff_distance_gauge.has_been_updated() else np.array( [0.0, 0.0, 0.0]) ]) self.custom_variables[ "Dice score per class per epoch"] = self._class_dice_gauge_on_patches.compute() if self._class_dice_gauge_on_patches.has_been_updated() else np.array( [0.0, 0.0, 0.0]) self.custom_variables[ "Dice score per class per epoch on reconstructed image"] = self._class_dice_gauge_on_reconstructed_images.compute() if self._class_dice_gauge_on_reconstructed_images.has_been_updated() else np.array( [0.0, 0.0, 0.0]) self.custom_variables[ "Dice score per class per epoch on reconstructed iSEG image"] = self._class_dice_gauge_on_reconstructed_iseg_images.compute() if self._class_dice_gauge_on_reconstructed_iseg_images.has_been_updated() else np.array( [0.0, 0.0, 0.0]) self.custom_variables[ "Dice score per class per epoch on reconstructed MRBrainS image"] = self._class_dice_gauge_on_reconstructed_mrbrains_images.compute() if self._class_dice_gauge_on_reconstructed_mrbrains_images.has_been_updated() else np.array( [0.0, 0.0, 0.0]) self.custom_variables[ "Dice score per class per epoch on reconstructed ABIDE image"] = self._class_dice_gauge_on_reconstructed_abide_images.compute() if self._class_dice_gauge_on_reconstructed_abide_images.has_been_updated() else np.array( [0.0, 0.0, 0.0]) self.custom_variables[ "Hausdorff Distance per class per epoch on reconstructed iSEG image"] = self._hausdorff_distance_gauge_on_reconstructed_iseg_images.compute() if self._hausdorff_distance_gauge_on_reconstructed_iseg_images.has_been_updated() else np.array( [0.0, 0.0, 0.0]) self.custom_variables[ "Hausdorff Distance per class per epoch on reconstructed MRBrainS image"] = self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.compute() if self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.has_been_updated() else np.array( [0.0, 0.0, 0.0]) self.custom_variables[ "Hausdorff Distance per class per epoch on reconstructed ABIDE image"] = self._hausdorff_distance_gauge_on_reconstructed_abide_images.compute() if self._hausdorff_distance_gauge_on_reconstructed_abide_images.has_been_updated() else np.array( [0.0, 0.0, 0.0]) if self._valid_dice_gauge.compute() > self._previous_mean_dice: new_table = to_html_per_dataset( ["CSF", "Grey Matter", "White Matter"], ["DSC", "HD"], [ [ self._iSEG_dice_gauge.compute() if self._iSEG_dice_gauge.has_been_updated() else np.array( [0.0, 0.0, 0.0]), self._iSEG_hausdorff_gauge.compute() if self._iSEG_hausdorff_gauge.has_been_updated() else np.array( [0.0, 0.0, 0.0])], [ self._MRBrainS_dice_gauge.compute() if self._MRBrainS_dice_gauge.has_been_updated() else np.array( [0.0, 0.0, 0.0]), self._MRBrainS_hausdorff_gauge.compute() if self._MRBrainS_hausdorff_gauge.has_been_updated() else np.array( [0.0, 0.0, 0.0])], [ self._ABIDE_dice_gauge.compute() if self._ABIDE_dice_gauge.has_been_updated() else np.array( [0.0, 0.0, 0.0]), self._ABIDE_hausdorff_gauge.compute() if self._ABIDE_hausdorff_gauge.has_been_updated() else np.array( [0.0, 0.0, 0.0])]], ["iSEG", "MRBrainS", "ABIDE"]) self.custom_variables["Per-Dataset Metric Table"] = new_table self._previous_mean_dice = self._valid_dice_gauge.compute() self._previous_per_dataset_table = new_table else: self.custom_variables["Per-Dataset Metric Table"] = self._previous_per_dataset_table self._valid_dice_gauge.reset() self.custom_variables["Mean Hausdorff Distance"] = [ self._class_hausdorff_distance_gauge.compute().mean() if self._class_hausdorff_distance_gauge.has_been_updated() else np.array( [0.0])] self.custom_variables[ "Per Dataset Mean Hausdorff Distance"] = self._per_dataset_hausdorff_distance_gauge.compute() def _update_image_plots(self, phase, inputs, segmenter_predictions, target, dataset_ids): inputs = torch.nn.functional.interpolate(inputs, scale_factor=5, mode="trilinear", align_corners=True).numpy() segmenter_predictions = torch.nn.functional.interpolate( torch.argmax(torch.nn.functional.softmax(segmenter_predictions, dim=1), dim=1, keepdim=True).float(), scale_factor=5, mode="nearest").numpy() target = torch.nn.functional.interpolate(target.float(), scale_factor=5, mode="nearest").numpy() self.custom_variables[ "{} Input Batch Process {}".format(phase, self._run_config.local_rank)] = self._slicer.get_slice( SliceType.AXIAL, inputs, inputs.shape[2] // 2) self.custom_variables[ "{} Segmented Batch Process {}".format(phase, self._run_config.local_rank)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, segmenter_predictions, segmenter_predictions.shape[2] // 2) self.custom_variables[ "{} Segmentation Ground Truth Batch Process {}".format(phase, self._run_config.local_rank)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, target, target.shape[2] // 2) self.custom_variables[ "{} Label Map Batch Process {}".format(phase, self._run_config.local_rank)] = self._label_mapper.get_label_map( dataset_ids) def _update_histograms(self, inputs, target): self.custom_variables["Input Intensity Histogram"] = flatten(inputs.cpu().detach()) self.custom_variables["Background Input Intensity Histogram"] = inputs[ torch.where(target[IMAGE_TARGET] == 0)].cpu().detach() self.custom_variables["CSF Input Intensity Histogram"] = inputs[ torch.where(target[IMAGE_TARGET] == 1)].cpu().detach() self.custom_variables["GM Input Intensity Histogram"] = inputs[ torch.where(target[IMAGE_TARGET] == 2)].cpu().detach() self.custom_variables["WM Input Intensity Histogram"] = inputs[ torch.where(target[IMAGE_TARGET] == 3)].cpu().detach()
class DualUNetTrainer(Trainer): def __init__(self, training_config, model_trainers: List[ModelTrainer], train_data_loader: DataLoader, valid_data_loader: DataLoader, test_data_loader: DataLoader, reconstruction_datasets: List[Dataset], normalize_reconstructors: list, input_reconstructors: list, segmentation_reconstructors: list, augmented_reconstructors: list, gt_reconstructors: list, run_config: RunConfiguration, dataset_config: dict, save_folder: str): super(DualUNetTrainer, self).__init__("DualUNetTrainer", train_data_loader, valid_data_loader, test_data_loader, model_trainers, run_config) self._training_config = training_config self._run_config = run_config self._dataset_configs = dataset_config self._patience_segmentation = training_config.patience_segmentation self._slicer = ImageSlicer() self._seg_slicer = SegmentationSlicer() self._label_mapper = LabelMapper() self._reconstruction_datasets = reconstruction_datasets self._normalize_reconstructors = normalize_reconstructors self._input_reconstructors = input_reconstructors self._gt_reconstructors = gt_reconstructors self._segmentation_reconstructors = segmentation_reconstructors self._augmented_reconstructors = augmented_reconstructors self._class_hausdorff_distance_gauge = AverageGauge() self._mean_hausdorff_distance_gauge = AverageGauge() self._per_dataset_hausdorff_distance_gauge = AverageGauge() self._iSEG_dice_gauge = AverageGauge() self._MRBrainS_dice_gauge = AverageGauge() self._ABIDE_dice_gauge = AverageGauge() self._iSEG_hausdorff_gauge = AverageGauge() self._MRBrainS_hausdorff_gauge = AverageGauge() self._ABIDE_hausdorff_gauge = AverageGauge() self._valid_dice_gauge = AverageGauge() self._class_dice_gauge_on_patches = AverageGauge() self._class_dice_gauge_on_reconstructed_images = AverageGauge() self._class_dice_gauge_on_reconstructed_iseg_images = AverageGauge() self._class_dice_gauge_on_reconstructed_mrbrains_images = AverageGauge( ) self._class_dice_gauge_on_reconstructed_abide_images = AverageGauge() self._hausdorff_distance_gauge_on_reconstructed_iseg_images = AverageGauge( ) self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images = AverageGauge( ) self._hausdorff_distance_gauge_on_reconstructed_abide_images = AverageGauge( ) self._js_div_inputs_gauge = AverageGauge() self._js_div_gen_gauge = AverageGauge() self._general_confusion_matrix_gauge = ConfusionMatrix(num_classes=4) self._iSEG_confusion_matrix_gauge = ConfusionMatrix(num_classes=4) self._MRBrainS_confusion_matrix_gauge = ConfusionMatrix(num_classes=4) self._ABIDE_confusion_matrix_gauge = ConfusionMatrix(num_classes=4) self._previous_mean_dice = 0.0 self._previous_per_dataset_table = "" self._start_time = time.time() self._save_folder = save_folder self._sampler = Sampler(0.33) self._is_sliced = True if isinstance(self._reconstruction_datasets[0], SliceDataset) else False print("Total number of parameters: {}".format( sum(p.numel() for p in self._model_trainers[GENERATOR].parameters()) + sum(p.numel() for p in self._model_trainers[SEGMENTER].parameters()))) pynvml.nvmlInit() def _train_g(self, G: ModelTrainer, real, backward=True): G.zero_grad() gen_pred = torch.nn.functional.sigmoid(G.forward(real)) loss_G = G.compute_and_update_train_loss("MSELoss", gen_pred, real) metric = G.compute_metric("MeanSquaredError", gen_pred, real) G.update_train_metric("MeanSquaredError", metric / 32768) if backward: loss_G.backward() G.step() return gen_pred def _valid_g(self, G: ModelTrainer, real): gen_pred = torch.nn.functional.sigmoid(G.forward(real)) G.compute_and_update_valid_loss("MSELoss", gen_pred, real) metric = G.compute_metric("MeanSquaredError", gen_pred, real) G.update_valid_metric("MeanSquaredError", metric / 32768) return gen_pred def _test_g(self, G: ModelTrainer, real): gen_pred = torch.nn.functional.sigmoid(G.forward(real)) G.compute_and_update_test_loss("MSELoss", gen_pred, real) metric = G.compute_metric("MeanSquaredError", gen_pred, real) G.update_test_metric("MeanSquaredError", metric / 32768) return gen_pred def _train_s(self, S: ModelTrainer, inputs, target, backward=True): S.zero_grad() target_ohe = to_onehot(torch.squeeze(target, dim=1).long(), num_classes=4) target = torch.squeeze(target, dim=1).long() seg_pred = torch.nn.functional.softmax(S.forward(inputs), dim=1) loss_S = S.compute_loss("DiceLoss", seg_pred, target_ohe) S.update_train_loss("DiceLoss", loss_S.mean()) metrics = S.compute_metrics(seg_pred, target) metrics["Dice"] = metrics["Dice"].mean() metrics["IoU"] = metrics["IoU"].mean() S.update_train_metrics(metrics) if backward: loss_S.mean().backward() S.step() return seg_pred, loss_S def _valid_s(self, S: ModelTrainer, inputs, target): target_ohe = to_onehot(torch.squeeze(target, dim=1).long(), num_classes=4) target = torch.squeeze(target, dim=1).long() seg_pred = torch.nn.functional.softmax(S.forward(inputs), dim=1) loss_S = S.compute_loss("DiceLoss", seg_pred, target_ohe) S.update_valid_loss("DiceLoss", loss_S.mean()) metrics = S.compute_metrics(seg_pred, target) metrics["Dice"] = metrics["Dice"].mean() metrics["IoU"] = metrics["IoU"].mean() S.update_valid_metrics(metrics) return seg_pred, loss_S def _test_s(self, S: ModelTrainer, inputs, target, metric_gauge: AverageGauge): target_ohe = to_onehot(torch.squeeze(target, dim=1).long(), num_classes=4) target = torch.squeeze(target, dim=1).long() seg_pred = torch.nn.functional.softmax(S.forward(inputs), dim=1) loss_S = S.compute_loss("DiceLoss", seg_pred, target_ohe) S.update_test_loss("DiceLoss", loss_S.mean()) metrics = S.compute_metrics(seg_pred, target) metric_gauge.update(np.array(metrics["Dice"])) metrics["Dice"] = metrics["Dice"].mean() metrics["IoU"] = metrics["IoU"].mean() S.update_test_metrics(metrics) return seg_pred, loss_S def train_step(self, inputs, target): inputs, target = self._sampler(inputs, target) if self._should_activate_autoencoder(): gen_pred = self._train_g(self._model_trainers[GENERATOR], inputs[NON_AUGMENTED_INPUTS]) seg_pred, _ = self._train_s( self._model_trainers[SEGMENTER], inputs[NON_AUGMENTED_INPUTS], target[NON_AUGMENTED_TARGETS][IMAGE_TARGET]) if self.current_train_step % 500 == 0: self._update_image_plots( self.phase, inputs[NON_AUGMENTED_INPUTS].cpu().detach(), gen_pred.cpu().detach(), seg_pred.cpu().detach(), target[NON_AUGMENTED_TARGETS][IMAGE_TARGET].cpu().detach(), target[NON_AUGMENTED_TARGETS][DATASET_ID].cpu().detach()) if self._should_activate_segmentation(): gen_pred = self._train_g(self._model_trainers[GENERATOR], inputs[AUGMENTED_INPUTS], backward=False) seg_pred, loss_S = self._train_s( self._model_trainers[SEGMENTER], gen_pred, target[AUGMENTED_TARGETS][IMAGE_TARGET], backward=False) loss_S.mean().backward() self._model_trainers[SEGMENTER].step() self._model_trainers[GENERATOR].step() if self.current_train_step % 500 == 0: self._update_image_plots( self.phase, inputs[AUGMENTED_INPUTS].cpu().detach(), gen_pred.cpu().detach(), seg_pred.cpu().detach(), target[AUGMENTED_TARGETS][IMAGE_TARGET].cpu().detach(), target[AUGMENTED_TARGETS][DATASET_ID].cpu().detach()) def validate_step(self, inputs, target): if self._should_activate_autoencoder(): gen_pred = self._valid_g(self._model_trainers[GENERATOR], inputs[NON_AUGMENTED_INPUTS]) seg_pred, _ = self._valid_s(self._model_trainers[SEGMENTER], inputs[NON_AUGMENTED_INPUTS], target[IMAGE_TARGET]) if self._should_activate_segmentation(): gen_pred = self._valid_g(self._model_trainers[GENERATOR], inputs[AUGMENTED_INPUTS]) seg_pred, _ = self._valid_s(self._model_trainers[SEGMENTER], gen_pred, target[IMAGE_TARGET]) if self.current_valid_step % 100 == 0: self._update_image_plots( self.phase, inputs[NON_AUGMENTED_INPUTS].cpu().detach(), gen_pred.cpu().detach(), seg_pred.cpu().detach(), target[IMAGE_TARGET].cpu().detach(), target[DATASET_ID].cpu().detach()) def test_step(self, inputs, target): if self._should_activate_autoencoder(): gen_pred = self._test_g(self._model_trainers[GENERATOR], inputs[NON_AUGMENTED_INPUTS]) seg_pred, _ = self._test_s(self._model_trainers[SEGMENTER], inputs[NON_AUGMENTED_INPUTS], target[IMAGE_TARGET], self._class_dice_gauge_on_patches) if self._should_activate_segmentation(): gen_pred = self._test_g(self._model_trainers[GENERATOR], inputs[AUGMENTED_INPUTS]) seg_pred, loss_S = self._test_s(self._model_trainers[SEGMENTER], gen_pred, target[IMAGE_TARGET], self._class_dice_gauge_on_patches) if seg_pred[torch.where( target[DATASET_ID] == ISEG_ID)].shape[0] != 0: self._iSEG_dice_gauge.update( np.array(self._model_trainers[SEGMENTER].compute_metrics( torch.nn.functional.softmax(seg_pred[torch.where( target[DATASET_ID] == ISEG_ID)], dim=1), torch.squeeze(target[IMAGE_TARGET][torch.where( target[DATASET_ID] == ISEG_ID)], dim=1).long())["Dice"].numpy())) self._iSEG_hausdorff_gauge.update( mean_hausdorff_distance( to_onehot(torch.argmax(torch.nn.functional.softmax( seg_pred[torch.where( target[DATASET_ID] == ISEG_ID)], dim=1), dim=1), num_classes=4), to_onehot(torch.squeeze( target[IMAGE_TARGET][torch.where( target[DATASET_ID] == ISEG_ID)], dim=1).long(), num_classes=4))[-3:]) self._iSEG_confusion_matrix_gauge.update( (to_onehot(torch.argmax(torch.nn.functional.softmax( seg_pred[torch.where(target[DATASET_ID] == ISEG_ID)], dim=1), dim=1, keepdim=False), num_classes=4), torch.squeeze(target[IMAGE_TARGET][torch.where( target[DATASET_ID] == ISEG_ID)].long(), dim=1))) else: self._iSEG_dice_gauge.update(np.zeros((3, ))) self._iSEG_hausdorff_gauge.update(np.zeros((3, ))) if seg_pred[torch.where( target[DATASET_ID] == MRBRAINS_ID)].shape[0] != 0: self._MRBrainS_dice_gauge.update( np.array(self._model_trainers[SEGMENTER].compute_metrics( torch.nn.functional.softmax(seg_pred[torch.where( target[DATASET_ID] == MRBRAINS_ID)], dim=1), torch.squeeze(target[IMAGE_TARGET][torch.where( target[DATASET_ID] == MRBRAINS_ID)], dim=1).long())["Dice"].numpy())) self._MRBrainS_hausdorff_gauge.update( mean_hausdorff_distance( to_onehot(torch.argmax(torch.nn.functional.softmax( seg_pred[torch.where( target[DATASET_ID] == MRBRAINS_ID)], dim=1), dim=1), num_classes=4), to_onehot(torch.squeeze( target[IMAGE_TARGET][torch.where( target[DATASET_ID] == MRBRAINS_ID)], dim=1).long(), num_classes=4))[-3:]) self._MRBrainS_confusion_matrix_gauge.update( (to_onehot(torch.argmax(torch.nn.functional.softmax( seg_pred[torch.where( target[DATASET_ID] == MRBRAINS_ID)], dim=1), dim=1, keepdim=False), num_classes=4), torch.squeeze(target[IMAGE_TARGET][torch.where( target[DATASET_ID] == MRBRAINS_ID)].long(), dim=1))) else: self._MRBrainS_dice_gauge.update(np.zeros((3, ))) self._MRBrainS_hausdorff_gauge.update(np.zeros((3, ))) if seg_pred[torch.where( target[DATASET_ID] == ABIDE_ID)].shape[0] != 0: self._ABIDE_dice_gauge.update( np.array(self._model_trainers[SEGMENTER].compute_metrics( torch.nn.functional.softmax(seg_pred[torch.where( target[DATASET_ID] == ABIDE_ID)], dim=1), torch.squeeze(target[IMAGE_TARGET][torch.where( target[DATASET_ID] == ABIDE_ID)], dim=1).long())["Dice"].numpy())) self._ABIDE_hausdorff_gauge.update( mean_hausdorff_distance( to_onehot(torch.argmax(torch.nn.functional.softmax( seg_pred[torch.where( target[DATASET_ID] == ABIDE_ID)], dim=1), dim=1), num_classes=4), to_onehot(torch.squeeze( target[IMAGE_TARGET][torch.where( target[DATASET_ID] == ABIDE_ID)], dim=1).long(), num_classes=4))[-3:]) self._ABIDE_confusion_matrix_gauge.update( (to_onehot(torch.argmax(torch.nn.functional.softmax( seg_pred[torch.where(target[DATASET_ID] == ABIDE_ID)], dim=1), dim=1, keepdim=False), num_classes=4), torch.squeeze(target[IMAGE_TARGET][torch.where( target[DATASET_ID] == ABIDE_ID)].long(), dim=1))) self._class_hausdorff_distance_gauge.update( mean_hausdorff_distance( to_onehot(torch.argmax(torch.nn.functional.softmax( seg_pred, dim=1), dim=1), num_classes=4), to_onehot(torch.squeeze(target[IMAGE_TARGET], dim=1).long(), num_classes=4))[-3:]) self._general_confusion_matrix_gauge.update( (to_onehot(torch.argmax(torch.nn.functional.softmax(seg_pred, dim=1), dim=1, keepdim=False), num_classes=4), torch.squeeze(target[IMAGE_TARGET].long(), dim=1))) inputs_reshaped = inputs[AUGMENTED_INPUTS].reshape( inputs[AUGMENTED_INPUTS].shape[0], inputs[AUGMENTED_INPUTS].shape[1] * inputs[AUGMENTED_INPUTS].shape[2] * inputs[AUGMENTED_INPUTS].shape[3] * inputs[AUGMENTED_INPUTS].shape[4]) c, d, h, w = inputs[AUGMENTED_INPUTS].shape[1], inputs[AUGMENTED_INPUTS].shape[2], \ inputs[AUGMENTED_INPUTS].shape[3], inputs[AUGMENTED_INPUTS].shape[4] hist_inputs = torch.cat([ torch.histc(inputs[AUGMENTED_INPUTS][i].view(1, c * d * h * w), bins=256, min=0, max=1).unsqueeze(0) for i in range(inputs[0].shape[0]) ]).unsqueeze(0) hist_inputs = hist_inputs / (c * d * h * w) hist_inputs = torch.nn.Softmax(dim=2)(hist_inputs) hist_gen = torch.cat([ torch.histc(gen_pred[i].view(1, c * d * h * w), bins=256, min=0, max=1).unsqueeze(0) for i in range(gen_pred.shape[0]) ]).unsqueeze(0) hist_gen = hist_gen / (c * d * h * w) hist_gen = torch.nn.Softmax(dim=2)(hist_gen) self._js_div_inputs_gauge.update(js_div(hist_inputs).item()) self._js_div_gen_gauge.update(js_div(hist_gen).item()) if self.current_test_step % 100 == 0: self._update_histograms(inputs[NON_AUGMENTED_INPUTS], target, gen_pred) self._update_image_plots( self.phase, inputs[NON_AUGMENTED_INPUTS].cpu().detach(), gen_pred.cpu().detach(), seg_pred.cpu().detach(), target[IMAGE_TARGET].cpu().detach(), target[DATASET_ID].cpu().detach()) def scheduler_step(self): self._model_trainers[GENERATOR].scheduler_step() self._model_trainers[SEGMENTER].scheduler_step() def on_epoch_begin(self): self._class_hausdorff_distance_gauge.reset() self._mean_hausdorff_distance_gauge.reset() self._iSEG_dice_gauge.reset() self._MRBrainS_dice_gauge.reset() self._ABIDE_dice_gauge.reset() self._iSEG_hausdorff_gauge.reset() self._MRBrainS_hausdorff_gauge.reset() self._ABIDE_hausdorff_gauge.reset() self._class_dice_gauge_on_patches.reset() self._js_div_inputs_gauge.reset() self._js_div_gen_gauge.reset() self._general_confusion_matrix_gauge.reset() self._iSEG_confusion_matrix_gauge.reset() self._MRBrainS_confusion_matrix_gauge.reset() self._ABIDE_confusion_matrix_gauge.reset() if self._current_epoch == self._training_config.patience_segmentation: self._model_trainers[GENERATOR].optimizer_lr = 0.001 def on_test_epoch_end(self): if self.epoch % 10 == 0: self._per_dataset_hausdorff_distance_gauge.reset() self._class_dice_gauge_on_reconstructed_iseg_images.reset() self._class_dice_gauge_on_reconstructed_mrbrains_images.reset() self._class_dice_gauge_on_reconstructed_abide_images.reset() self._hausdorff_distance_gauge_on_reconstructed_iseg_images.reset() self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.reset( ) self._hausdorff_distance_gauge_on_reconstructed_abide_images.reset( ) all_patches, ground_truth_patches = get_all_patches( self._reconstruction_datasets, self._is_sliced) img_input = rebuild_image(self._dataset_configs.keys(), all_patches, self._input_reconstructors) img_gt = rebuild_image(self._dataset_configs.keys(), ground_truth_patches, self._gt_reconstructors) img_norm = rebuild_image(self._dataset_configs.keys(), all_patches, self._normalize_reconstructors) img_seg = rebuild_image(self._dataset_configs.keys(), all_patches, self._segmentation_reconstructors) save_rebuilt_image(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_input, "Input") save_rebuilt_image(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_gt, "Ground_Truth") save_rebuilt_image(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_norm, "Normalized") save_rebuilt_image(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_seg, "Segmented") if self._training_config.build_augmented_images: img_augmented = rebuild_image(self._dataset_configs.keys(), all_patches, self._augmented_reconstructors) augmented_minus_inputs, normalized_minus_inputs = rebuild_augmented_images( img_augmented, img_input, img_gt, img_norm, img_seg) save_augmented_rebuilt_images(self._current_epoch, self._save_folder, self._dataset_configs.keys(), img_augmented, augmented_minus_inputs, normalized_minus_inputs) mean_mhd = [] for dataset in self._dataset_configs.keys(): self.custom_variables[ "Reconstructed Normalized {} Image".format( dataset)] = self._slicer.get_slice( SliceType.AXIAL, np.expand_dims( np.expand_dims(img_norm[dataset], 0), 0), 160) self.custom_variables[ "Reconstructed Segmented {} Image".format( dataset)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, np.expand_dims(np.expand_dims(img_seg[dataset], 0), 0), 160).squeeze(0) self.custom_variables[ "Reconstructed Ground Truth {} Image".format( dataset)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, np.expand_dims(np.expand_dims(img_gt[dataset], 0), 0), 160).squeeze(0) self.custom_variables["Reconstructed Input {} Image".format( dataset)] = self._slicer.get_slice( SliceType.AXIAL, np.expand_dims(np.expand_dims(img_input[dataset], 0), 0), 160) if self._training_config.build_augmented_images: self.custom_variables[ "Reconstructed Augmented Input {} Image".format( dataset)] = self._slicer.get_slice( SliceType.AXIAL, np.expand_dims( np.expand_dims(img_augmented[dataset], 0), 0), 160) self.custom_variables[ "Reconstructed Initial Noise {} Image".format( dataset)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, np.expand_dims( np.expand_dims( augmented_minus_inputs[dataset], 0), 0), 160).squeeze(0) self.custom_variables[ "Reconstructed Noise {} After Normalization".format( dataset)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, np.expand_dims( np.expand_dims( normalized_minus_inputs[dataset], 0), 0), 160).squeeze(0) else: self.custom_variables[ "Reconstructed Augmented Input {} Image".format( dataset)] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Initial Noise {} Image".format( dataset)] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Noise {} After Normalization".format( dataset)] = np.zeros((224, 192)) mean_mhd.append( mean_hausdorff_distance( to_onehot(torch.tensor(img_gt[dataset], dtype=torch.long), num_classes=4), to_onehot(torch.tensor(img_seg[dataset], dtype=torch.long), num_classes=4))[-3:].mean()) metric = self._model_trainers[SEGMENTER].compute_metrics( to_onehot(torch.tensor( img_seg[dataset]).unsqueeze(0).long(), num_classes=4), torch.tensor(img_gt[dataset]).unsqueeze(0).long()) self._class_dice_gauge_on_reconstructed_images.update( np.array(metric["Dice"])) self._per_dataset_hausdorff_distance_gauge.update( np.array(mean_mhd)) if "iSEG" in img_seg: metric = self._model_trainers[SEGMENTER].compute_metrics( to_onehot(torch.tensor( img_seg["iSEG"]).unsqueeze(0).long(), num_classes=4), torch.tensor(img_gt["iSEG"]).unsqueeze(0).long()) self._class_dice_gauge_on_reconstructed_iseg_images.update( np.array(metric["Dice"])) self._hausdorff_distance_gauge_on_reconstructed_iseg_images.update( mean_hausdorff_distance( to_onehot(torch.tensor(img_gt["iSEG"], dtype=torch.long), num_classes=4), to_onehot(torch.tensor(img_seg["iSEG"], dtype=torch.long), num_classes=4))[-3:]) else: self._class_dice_gauge_on_reconstructed_iseg_images.update( np.array([0.0, 0.0, 0.0])) self._hausdorff_distance_gauge_on_reconstructed_iseg_images.update( np.array([0.0, 0.0, 0.0])) if "MRBrainS" in img_seg: metric = self._model_trainers[SEGMENTER].compute_metrics( to_onehot(torch.tensor( img_seg["MRBrainS"]).unsqueeze(0).long(), num_classes=4), torch.tensor(img_gt["MRBrainS"]).unsqueeze(0).long()) self._class_dice_gauge_on_reconstructed_mrbrains_images.update( np.array(metric["Dice"])) self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.update( mean_hausdorff_distance( to_onehot(torch.tensor(img_gt["MRBrainS"], dtype=torch.long), num_classes=4), to_onehot(torch.tensor(img_seg["MRBrainS"], dtype=torch.long), num_classes=4))[-3:]) else: self._class_dice_gauge_on_reconstructed_mrbrains_images.update( np.array([0.0, 0.0, 0.0])) self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.update( np.array([0.0, 0.0, 0.0])) if "ABIDE" in img_seg: metric = self._model_trainers[SEGMENTER].compute_metrics( to_onehot(torch.tensor( img_seg["ABIDE"]).unsqueeze(0).long(), num_classes=4), torch.tensor(img_gt["ABIDE"]).unsqueeze(0).long()) self._class_dice_gauge_on_reconstructed_abide_images.update( np.array(metric["Dice"])) self._hausdorff_distance_gauge_on_reconstructed_abide_images.update( mean_hausdorff_distance( to_onehot(torch.tensor(img_gt["ABIDE"], dtype=torch.long), num_classes=4), to_onehot(torch.tensor(img_seg["ABIDE"], dtype=torch.long), num_classes=4))[-3:]) else: self._class_dice_gauge_on_reconstructed_abide_images.update( np.array([0.0, 0.0, 0.0])) self._hausdorff_distance_gauge_on_reconstructed_abide_images.update( np.array([0.0, 0.0, 0.0])) if len(img_input) == 3: self.custom_variables[ "Reconstructed Images Histograms"] = cv2.imread( construct_triple_histrogram( img_norm["iSEG"], img_input["iSEG"], img_norm["MRBrainS"], img_input["MRBrainS"], img_norm["ABIDE"], img_input["ABIDE"])).transpose( (2, 0, 1)) elif len(img_input) == 2: self.custom_variables[ "Reconstructed Images Histograms"] = cv2.imread( construct_double_histrogram( img_norm["iSEG"], img_input["iSEG"], img_norm["MRBrainS"], img_input["MRBrainS"])).transpose((2, 0, 1)) elif len(img_input) == 1: self.custom_variables[ "Reconstructed Images Histograms"] = cv2.imread( construct_single_histogram( img_norm[list(self._dataset_configs.keys())[0]], img_input[list(self._dataset_configs.keys())[0]], )).transpose((2, 0, 1)) if "ABIDE" not in self._dataset_configs.keys(): self.custom_variables[ "Reconstructed Normalized ABIDE Image"] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Segmented ABIDE Image"] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Ground Truth ABIDE Image"] = np.zeros( (224, 192)) self.custom_variables[ "Reconstructed Input ABIDE Image"] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Initial Noise ABIDE Image"] = np.zeros( (224, 192)) self.custom_variables[ "Reconstructed Noise ABIDE After Normalization"] = np.zeros( (224, 192)) if "iSEG" not in self._dataset_configs.keys(): self.custom_variables[ "Reconstructed Normalized iSEG Image"] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Segmented iSEG Image"] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Ground Truth iSEG Image"] = np.zeros((224, 192)) self.custom_variables["Reconstructed Input iSEG Image"] = np.zeros( (224, 192)) self.custom_variables[ "Reconstructed Initial Noise iSEG Image"] = np.zeros( (224, 192)) self.custom_variables[ "Reconstructed Noise iSEG After Normalization"] = np.zeros( (224, 192)) if "MRBrainS" not in self._dataset_configs.keys(): self.custom_variables[ "Reconstructed Normalized MRBrainS Image"] = np.zeros( (224, 192)) self.custom_variables[ "Reconstructed Segmented MRBrainS Image"] = np.zeros( (224, 192)) self.custom_variables[ "Reconstructed Ground Truth MRBrainS Image"] = np.zeros( (224, 192)) self.custom_variables[ "Reconstructed Input MRBrainS Image"] = np.zeros((224, 192)) self.custom_variables[ "Reconstructed Initial Noise MRBrainS Image"] = np.zeros( (224, 192)) self.custom_variables[ "Reconstructed Noise MRBrainS After Normalization"] = np.zeros( (224, 192)) self.custom_variables["Runtime"] = to_html_time( timedelta(seconds=time.time() - self._start_time)) if self._general_confusion_matrix_gauge._num_examples != 0: self.custom_variables["Confusion Matrix"] = np.array( np.fliplr(self._general_confusion_matrix_gauge.compute().cpu(). detach().numpy())) else: self.custom_variables["Confusion Matrix"] = np.zeros((4, 4)) if self._iSEG_confusion_matrix_gauge._num_examples != 0: self.custom_variables["iSEG Confusion Matrix"] = np.array( np.fliplr(self._iSEG_confusion_matrix_gauge.compute().cpu(). detach().numpy())) else: self.custom_variables["iSEG Confusion Matrix"] = np.zeros((4, 4)) if self._MRBrainS_confusion_matrix_gauge._num_examples != 0: self.custom_variables["MRBrainS Confusion Matrix"] = np.array( np.fliplr(self._MRBrainS_confusion_matrix_gauge.compute().cpu( ).detach().numpy())) else: self.custom_variables["MRBrainS Confusion Matrix"] = np.zeros( (4, 4)) if self._ABIDE_confusion_matrix_gauge._num_examples != 0: self.custom_variables["ABIDE Confusion Matrix"] = np.array( np.fliplr(self._ABIDE_confusion_matrix_gauge.compute().cpu(). detach().numpy())) else: self.custom_variables["ABIDE Confusion Matrix"] = np.zeros((4, 4)) self.custom_variables["Metric Table"] = to_html( ["CSF", "Grey Matter", "White Matter"], ["DSC", "HD"], [ self._class_dice_gauge_on_patches.compute() if self._class_dice_gauge_on_patches.has_been_updated() else np.array([0.0, 0.0, 0.0]), self._class_hausdorff_distance_gauge.compute() if self._class_hausdorff_distance_gauge.has_been_updated() else np.array([0.0, 0.0, 0.0]) ]) self.custom_variables[ "Dice score per class per epoch"] = self._class_dice_gauge_on_patches.compute( ) if self._class_dice_gauge_on_patches.has_been_updated( ) else np.array([0.0, 0.0, 0.0]) self.custom_variables[ "Dice score per class per epoch on reconstructed image"] = self._class_dice_gauge_on_reconstructed_images.compute( ) if self._class_dice_gauge_on_reconstructed_images.has_been_updated( ) else np.array([0.0, 0.0, 0.0]) self.custom_variables[ "Dice score per class per epoch on reconstructed iSEG image"] = self._class_dice_gauge_on_reconstructed_iseg_images.compute( ) if self._class_dice_gauge_on_reconstructed_iseg_images.has_been_updated( ) else np.array([0.0, 0.0, 0.0]) self.custom_variables[ "Dice score per class per epoch on reconstructed MRBrainS image"] = self._class_dice_gauge_on_reconstructed_mrbrains_images.compute( ) if self._class_dice_gauge_on_reconstructed_mrbrains_images.has_been_updated( ) else np.array([0.0, 0.0, 0.0]) self.custom_variables[ "Dice score per class per epoch on reconstructed ABIDE image"] = self._class_dice_gauge_on_reconstructed_abide_images.compute( ) if self._class_dice_gauge_on_reconstructed_abide_images.has_been_updated( ) else np.array([0.0, 0.0, 0.0]) self.custom_variables[ "Hausdorff Distance per class per epoch on reconstructed iSEG image"] = self._hausdorff_distance_gauge_on_reconstructed_iseg_images.compute( ) if self._hausdorff_distance_gauge_on_reconstructed_iseg_images.has_been_updated( ) else np.array([0.0, 0.0, 0.0]) self.custom_variables[ "Hausdorff Distance per class per epoch on reconstructed MRBrainS image"] = self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.compute( ) if self._hausdorff_distance_gauge_on_reconstructed_mrbrains_images.has_been_updated( ) else np.array([0.0, 0.0, 0.0]) self.custom_variables[ "Hausdorff Distance per class per epoch on reconstructed ABIDE image"] = self._hausdorff_distance_gauge_on_reconstructed_abide_images.compute( ) if self._hausdorff_distance_gauge_on_reconstructed_abide_images.has_been_updated( ) else np.array([0.0, 0.0, 0.0]) if self._valid_dice_gauge.compute() > self._previous_mean_dice: new_table = to_html_per_dataset( ["CSF", "Grey Matter", "White Matter"], ["DSC", "HD"], [ [ self._iSEG_dice_gauge.compute() if self._iSEG_dice_gauge.has_been_updated() else np.array([0.0, 0.0, 0.0]), self._iSEG_hausdorff_gauge.compute() if self._iSEG_hausdorff_gauge.has_been_updated() else np.array([0.0, 0.0, 0.0]) ], [ self._MRBrainS_dice_gauge.compute() if self._MRBrainS_dice_gauge.has_been_updated() else np.array([0.0, 0.0, 0.0]), self._MRBrainS_hausdorff_gauge.compute() if self._MRBrainS_hausdorff_gauge.has_been_updated() else np.array([0.0, 0.0, 0.0]) ], [ self._ABIDE_dice_gauge.compute() if self._ABIDE_dice_gauge.has_been_updated() else np.array([0.0, 0.0, 0.0]), self._ABIDE_hausdorff_gauge.compute() if self._ABIDE_hausdorff_gauge.has_been_updated() else np.array([0.0, 0.0, 0.0]) ] ], ["iSEG", "MRBrainS", "ABIDE"]) self.custom_variables["Per-Dataset Metric Table"] = new_table self._previous_mean_dice = self._valid_dice_gauge.compute() self._previous_per_dataset_table = new_table else: self.custom_variables[ "Per-Dataset Metric Table"] = self._previous_per_dataset_table self._valid_dice_gauge.reset() self.custom_variables["Jensen-Shannon Table"] = to_html_JS( ["Input data", "Generated Data"], ["JS Divergence"], [ self._js_div_inputs_gauge.compute() if self._js_div_gen_gauge.has_been_updated() else np.array([0.0]), self._js_div_gen_gauge.compute() if self._js_div_gen_gauge.has_been_updated() else np.array([0.0]) ]) self.custom_variables["Jensen-Shannon Divergence"] = [ self._js_div_inputs_gauge.compute(), self._js_div_gen_gauge.compute() ] self.custom_variables["Mean Hausdorff Distance"] = [ self._class_hausdorff_distance_gauge.compute().mean() if self._class_hausdorff_distance_gauge.has_been_updated() else np.array([0.0]) ] self.custom_variables[ "Per Dataset Mean Hausdorff Distance"] = self._per_dataset_hausdorff_distance_gauge.compute( ) def _update_image_plots(self, phase, inputs, generator_predictions, segmenter_predictions, target, dataset_ids): inputs = torch.nn.functional.interpolate(inputs, scale_factor=5, mode="trilinear", align_corners=True).numpy() generator_predictions = torch.nn.functional.interpolate( generator_predictions, scale_factor=5, mode="trilinear", align_corners=True).numpy() segmenter_predictions = torch.nn.functional.interpolate( torch.argmax(torch.nn.functional.softmax(segmenter_predictions, dim=1), dim=1, keepdim=True).float(), scale_factor=5, mode="nearest").numpy() target = torch.nn.functional.interpolate(target.float(), scale_factor=5, mode="nearest").numpy() self.custom_variables["{} Input Batch Process {}".format( phase, self._run_config.local_rank)] = self._slicer.get_slice( SliceType.AXIAL, inputs, inputs.shape[2] // 2) self.custom_variables["{} Generated Batch Process {}".format( phase, self._run_config.local_rank)] = self._slicer.get_slice( SliceType.AXIAL, generator_predictions, generator_predictions.shape[2] // 2) self.custom_variables["{} Segmented Batch Process {}".format( phase, self._run_config.local_rank)] = self._seg_slicer.get_colored_slice( SliceType.AXIAL, segmenter_predictions, segmenter_predictions.shape[2] // 2) self.custom_variables[ "{} Segmentation Ground Truth Batch Process {}".format( phase, self._run_config.local_rank )] = self._seg_slicer.get_colored_slice(SliceType.AXIAL, target, target.shape[2] // 2) self.custom_variables["{} Label Map Batch Process {}".format( phase, self._run_config.local_rank)] = self._label_mapper.get_label_map( dataset_ids) def _should_activate_autoencoder(self): return self._current_epoch < self._patience_segmentation def _should_activate_segmentation(self): return self._current_epoch >= self._patience_segmentation def _update_histograms(self, inputs, target, gen_pred): self.custom_variables["Generated Intensity Histogram"] = flatten( gen_pred.cpu().detach()) self.custom_variables["Input Intensity Histogram"] = flatten( inputs.cpu().detach()) self.custom_variables["Per-Dataset Histograms"] = cv2.imread( construct_class_histogram(inputs, target, gen_pred)).transpose( (2, 0, 1)) self.custom_variables[ "Background Generated Intensity Histogram"] = gen_pred[torch.where( target[IMAGE_TARGET] == 0)].cpu().detach() self.custom_variables["CSF Generated Intensity Histogram"] = gen_pred[ torch.where(target[IMAGE_TARGET] == 1)].cpu().detach() self.custom_variables["GM Generated Intensity Histogram"] = gen_pred[ torch.where(target[IMAGE_TARGET] == 2)].cpu().detach() self.custom_variables["WM Generated Intensity Histogram"] = gen_pred[ torch.where(target[IMAGE_TARGET] == 3)].cpu().detach() self.custom_variables["Background Input Intensity Histogram"] = inputs[ torch.where(target[IMAGE_TARGET] == 0)].cpu().detach() self.custom_variables["CSF Input Intensity Histogram"] = inputs[ torch.where(target[IMAGE_TARGET] == 1)].cpu().detach() self.custom_variables["GM Input Intensity Histogram"] = inputs[ torch.where(target[IMAGE_TARGET] == 2)].cpu().detach() self.custom_variables["WM Input Intensity Histogram"] = inputs[ torch.where(target[IMAGE_TARGET] == 3)].cpu().detach()