B_B = 0.0,
B_C = 1,
B_vhalf = -26e-3,
B_vslope = -14e-3)
'''
Na_s_params = TauInfMinChannelParams(T_min=0.5,
T_vdep=2.2,
T_vhalf=-0.032,
T_vslope=0.012,
SS_min=0.15,
SS_vdep=0.85,
SS_vhalf=-0.045,
SS_vslope=0.0054,
T_power=1)
NaFparam = ChannelSettings(Xpow=3, Ypow=1, Zpow=0, Erev=narev, name='NaF')
# persistent Na_channel. Slow down from Dieter Jaeger
'''
NaS_m_params = AlphaBetaChannelParams(A_rate=76e3,
A_B=0,
A_C=1,
A_vhalf=-55.4e-3,
A_vslope=-13.6e-3,
B_rate=70e3,
B_B=0.0,
B_C=1,
B_vhalf=135e-3,
B_vslope=13.5e-3)
'''
NaS_m_params = AlphaBetaChannelParams(A_rate=30874.92399256788,
SS_vdep=1.0,
SS_vhalf=-0.01608849295680853,
SS_vslope=-0.01,
T_power=2)
Na_h_params = TauInfMinChannelParams(T_min=0.00027542296648548886,
T_vdep=0.0012001000718321953,
T_vhalf=-0.034845326172449564,
T_vslope=0.003,
SS_min=0.0,
SS_vdep=1.0,
SS_vhalf=-0.05284532617244956,
SS_vslope=0.006,
T_power=1)
NaFparam = ChannelSettings(Xpow=3, Ypow=1, Zpow=0, Erev=narev, name='NaF')
# This is from Migliore.
'''
KDrparam = ChannelSettings(Xpow=1, Ypow=0, Zpow=0, Erev=krev, name='KDr')
KDr_X_params = AlphaBetaChannelParams(A_rate = 28.2,
A_B = 0,
A_C = 0.0,
A_vhalf = 0,
A_vslope = -12.5e-3,
B_rate = 6.78,
B_B = 0.0,
B_C = 0.0,
B_vhalf = 0.0,
B_vslope = 33.5e-3)
B_vhalf=0.03256589042652369, B_vslope=0.005) Na_h_params = AlphaBetaChannelParams(A_rate=6810.764574104278, A_B=0.0, A_C=1, A_vhalf=0.07745302320358723, A_vslope=0.009, B_rate=6810.764574104278, B_B=0.0, B_C=1, B_vhalf=0.037453023203587225, B_vslope=-0.005) NaFparam = ChannelSettings(Xpow=3, Ypow=1, Zpow=0, Erev=narev, name='NaF') #KDrparam -Kv2 KDrparam = ChannelSettings(Xpow=4, Ypow=1, Zpow=0, Erev=krev, name='KDr') KDr_X_params = AlphaBetaChannelParams(A_rate=6094.508110357232, A_B=0.0, A_C=1, A_vhalf=-0.049, A_vslope=-0.015, B_rate=2595.8090099669694, B_B=0.0, B_C=1, B_vhalf=0.12, B_vslope=0.022)
CADIVS = 4001 #10 nM steps
kDr_X_params = AlphaBetaChannelParams(A_rate=6.5,
A_B=0,
A_C=0,
A_vhalf=0,
A_vslope=-12.5e-3,
B_rate=24,
B_B=0,
B_C=0,
B_vhalf=0,
B_vslope=33.5e-3)
kDr_Y_params = []
kDrparams = ChannelSettings(Xpow=1, Ypow=0, Zpow=0, Erev=-0.09, name='kDr')
KAdist_m_params = AlphaBetaChannelParams(A_rate=0.7,
A_B=0,
A_C=0,
A_vhalf=0,
A_vslope=-50e-3,
B_rate=0.15,
B_B=0,
B_C=0,
B_vhalf=-30.1001e-3,
B_vslope=9e-3)
KAdist_h_params = AlphaBetaChannelParams(A_rate=17,
A_B=0,
A_C=0,
B_C=0.0,
B_vhalf=0.0 - EREST_ACT,
B_vslope=18e-3)
Na_h_params = AlphaBetaChannelParams(A_rate=70,
A_B=0.0,
A_C=0.0,
A_vhalf=0.0 - EREST_ACT,
A_vslope=0.02,
B_rate=1000.0,
B_B=0.0,
B_C=1.0,
B_vhalf=-30e-3 - EREST_ACT,
B_vslope=-0.01)
NaSparam = ChannelSettings(Xpow=3, Ypow=1, Zpow=0, Erev=narev, name='Na')
K_n_params = AlphaBetaChannelParams(A_rate=-1e4 * (-10e-3 - EREST_ACT),
A_B=-1e4,
A_C=-1.0,
A_vhalf=-10e-3 - EREST_ACT,
A_vslope=-10e-3,
B_rate=0.125e3,
B_B=0.0,
B_C=0.0,
B_vhalf=0.0 - EREST_ACT,
B_vslope=80e-3)
KSparam = ChannelSettings(Xpow=4, Ypow=0, Zpow=0, Erev=krev, name='K')
Krp_X_params = AlphaBetaChannelParams(A_rate=16,
B_C=0.0,
B_vhalf=0.0,
B_vslope=42.248e-3)
NaF_Y_params = AlphaBetaChannelParams(A_rate=0.0035e3,
A_B=0.0,
A_C=0.0,
A_vhalf=0.0,
A_vslope=24.186e-3,
B_rate=-0.017e6 * 51.25e-3,
B_B=-0.017e6,
B_C=-1.0,
B_vhalf=51.25e-3,
B_vslope=-5.2e-3)
NaFparam = ChannelSettings(Xpow=3, Ypow=1, Zpow=0, Erev=narev, name='NaF')
qfactKv3132 = 1
Kv3132_X_params = AlphaBetaChannelParams(A_rate=95e3,
A_B=-1e6,
A_C=-1,
A_vhalf=-95e-3,
A_vslope=-11.8e-3,
B_rate=0.025e3,
B_B=0.0,
B_C=0.0,
B_vhalf=0.0e-3,
B_vslope=22.222e-3)
Kv3132param = ChannelSettings(Xpow=2, Ypow=0, Zpow=0, Erev=krev, name='Kv3132')
T_min=0.1e-3 / qfactNaF,
T_vdep=2.1025e-3 / qfactNaF,
T_vhalf=-62e-3,
T_vslope=8e-3,
T_power=2)
Na_h_params = TauInfMinChannelParams(T_min=2 * 0.2754e-3 / qfactNaF,
T_vdep=2 * 1.2e-3 / qfactNaF,
T_vhalf=-42e-3,
T_vslope=3e-3,
SS_min=0.0,
SS_vdep=1.0,
SS_vhalf=-60e-3,
SS_vslope=6e-3)
NaFparam = ChannelSettings(Xpow=3, Ypow=1, Zpow=0, Erev=narev, name='NaF')
Kirparam = ChannelSettings(Xpow=1, Ypow=0, Zpow=0, Erev=krev, name='Kir')
qfactKir = 1
Kir_X_params = AlphaBetaChannelParams(A_rate=0.008 * qfactKir,
A_B=0,
A_C=0.0,
A_vhalf=0,
A_vslope=11.0e-3,
B_rate=1000 * qfactKir,
B_B=0.0,
B_C=1.0,
B_vhalf=-40e-3,
B_vslope=-40e-3)
B_C=0.0,
B_vhalf=0.0 - EREST_ACT,
B_vslope=18e-3)
Na_h_params = AlphaBetaChannelParams(A_rate=70,
A_B=0.0,
A_C=0.0,
A_vhalf=0.0 - EREST_ACT,
A_vslope=0.02,
B_rate=1000.0,
B_B=0.0,
B_C=1.0,
B_vhalf=-30e-3 - EREST_ACT,
B_vslope=-0.01)
NaSparam = ChannelSettings(Xpow=3, Ypow=1, Zpow=0, Erev=narev, name='Na')
K_n_params = AlphaBetaChannelParams(A_rate=-1e4 * (-10e-3 - EREST_ACT),
A_B=-1e4,
A_C=-1.0,
A_vhalf=-10e-3 - EREST_ACT,
A_vslope=-10e-3,
B_rate=0.125e3,
B_B=0.0,
B_C=0.0,
B_vhalf=0.0 - EREST_ACT,
B_vslope=80e-3)
KSparam = ChannelSettings(Xpow=4, Ypow=0, Zpow=0, Erev=krev, name='K')
Channels = NamedDict('Channels',
