示例#1
0
    def kdeplot(x, color='w', **kwargs):
        global row_count, col_count

        if color != 'w':
            color = sns.light_palette(
                color, n_colors=len(data) + 1)[row_count + 1]
        sns.kdeplot(x, color=color, **kwargs)

        col_count = (col_count + 1) % n_feat

        if col_count == 0:
            row_count = (row_count + 1) % len(data)
def main():

    all_grps = df.loadExptGrps('GOL')

    WT_expt_grp = all_grps['WT_hidden_behavior_set']
    Df_expt_grp = all_grps['Df_hidden_behavior_set']

    behavior_fn = ra.fraction_licks_in_reward_zone
    behavior_kwargs = {}
    activity_label = 'Fraction of licks in reward zone'

    WT_colors = sns.light_palette(WT_color, 8)[::-1]
    Df_colors = sns.light_palette(Df_color, 7)[::-1]
    markers = ('o', 'v', '^', 'D', '*', 's')

    fig, axs = plt.subplots(4, 2, figsize=(8.5, 11))

    sns.despine(fig)

    wt_ax = axs[0, 0]
    df_ax = axs[0, 1]

    for ax in list(axs.flat)[2:]:
        ax.set_visible(False)

    wt_expt_grps = [
        WT_expt_grp.subGroup(list(expts['expt']), label=mouse)
        for mouse, expts in WT_expt_grp.dataframe(
            WT_expt_grp, include_columns=['mouseID']).groupby('mouseID')
    ]
    df_expt_grps = [
        Df_expt_grp.subGroup(list(expts['expt']), label=mouse)
        for mouse, expts in Df_expt_grp.dataframe(
            Df_expt_grp, include_columns=['mouseID']).groupby('mouseID')
    ]

    plotting.plot_metric(wt_ax,
                         wt_expt_grps,
                         metric_fn=behavior_fn,
                         activity_kwargs=behavior_kwargs,
                         groupby=[['expt'], ['condition_day']],
                         plotby=['condition_day'],
                         plot_method='line',
                         ms=5,
                         activity_label=activity_label,
                         colors=WT_colors,
                         markers=markers,
                         label_every_n=1,
                         label_groupby=False,
                         rotate_labels=False)
    wt_ax.set_xlabel('Day in Condition')
    wt_ax.set_title(WT_expt_grp.label())
    wt_ax.set_yticks([0, 0.1, 0.2, 0.3, 0.4, 0.5])
    wt_ax.set_xticklabels(['1', '2', '3', '1', '2', '3', '1', '2', '3'])
    label_conditions(wt_ax)
    wt_ax.get_legend().set_visible(False)
    wt_ax.tick_params(length=3, pad=2)

    plotting.plot_metric(df_ax,
                         df_expt_grps,
                         metric_fn=behavior_fn,
                         activity_kwargs=behavior_kwargs,
                         groupby=[['expt'], ['condition_day']],
                         plotby=['condition_day'],
                         plot_method='line',
                         ms=5,
                         activity_label=activity_label,
                         colors=Df_colors,
                         markers=markers,
                         label_every_n=1,
                         label_groupby=False,
                         rotate_labels=False)
    df_ax.set_xlabel('Day in Condition')
    df_ax.set_title(Df_expt_grp.label())
    df_ax.set_yticks([0, 0.1, 0.2, 0.3, 0.4, 0.5])
    df_ax.set_xticklabels(['1', '2', '3', '1', '2', '3', '1', '2', '3'])
    label_conditions(df_ax)
    df_ax.get_legend().set_visible(False)
    df_ax.tick_params(length=3, pad=2)

    misc.save_figure(fig, filename, save_dir=save_dir)
def main():
    all_grps = df.loadExptGrps('GOL')

    WT_expt_grp = all_grps['WT_place_set']
    Df_expt_grp = all_grps['Df_place_set']
    expt_grps = [WT_expt_grp, Df_expt_grp]
    if MALES_ONLY:
        for expt_grp in expt_grps:
            expt_grp.filter(lambda expt: expt.parent.get('sex') == 'M')

    WT_label = WT_expt_grp.label()
    Df_label = Df_expt_grp.label()

    fig = plt.figure(figsize=(8.5, 11))

    gs1 = plt.GridSpec(2,
                       5,
                       left=0.1,
                       right=0.3,
                       top=0.90,
                       bottom=0.67,
                       hspace=0.2)
    gs1_2 = plt.GridSpec(2,
                         5,
                         left=0.3,
                         right=0.5,
                         top=0.90,
                         bottom=0.67,
                         hspace=0.2)
    WT_1_heatmap_ax = fig.add_subplot(gs1[0, :-1])
    WT_3_heatmap_ax = fig.add_subplot(gs1_2[0, :-1])
    Df_1_heatmap_ax = fig.add_subplot(gs1[1, :-1])
    Df_3_heatmap_ax = fig.add_subplot(gs1_2[1, :-1])

    gs_cbar = plt.GridSpec(2,
                           10,
                           left=0.3,
                           right=0.5,
                           top=0.90,
                           bottom=0.67,
                           hspace=0.2)
    WT_colorbar_ax = fig.add_subplot(gs_cbar[0, -1])
    Df_colorbar_ax = fig.add_subplot(gs_cbar[1, -1])

    gs2 = plt.GridSpec(1, 10, left=0.1, right=0.5, top=0.6, bottom=0.45)
    pf_close_fraction_ax = fig.add_subplot(gs2[0, :4])
    pf_close_behav_corr_ax = fig.add_subplot(gs2[0, 5:])

    frac_near_range_2 = (-0.051, 0.551)
    behav_range_2 = (-0.051, 0.551)

    #
    # Heatmaps
    #

    WT_cmap = sns.light_palette(WT_color, as_cmap=True)
    WT_dataframe = lab.ExperimentGroup.dataframe(
        WT_expt_grp, include_columns=['X_condition', 'X_day', 'X_session'])

    WT_1_expt_grp = WT_expt_grp.subGroup(
        list(WT_dataframe[(WT_dataframe['X_condition'] == 'C')
                          & (WT_dataframe['X_day'] == '0') &
                          (WT_dataframe['X_session'] == '0')]['expt']))
    place.plotPositionHeatmap(WT_1_expt_grp,
                              roi_filter=WT_filter,
                              ax=WT_1_heatmap_ax,
                              norm='individual',
                              cbar_visible=False,
                              cmap=WT_cmap,
                              plotting_order='place_cells_only',
                              show_belt=False,
                              reward_in_middle=True)
    fix_heatmap_ax(WT_1_heatmap_ax, WT_1_expt_grp)
    WT_1_heatmap_ax.set_title(r'Condition $\mathrm{III}$: Day 1')
    WT_1_heatmap_ax.set_ylabel(WT_label)
    WT_1_heatmap_ax.set_xlabel('')

    WT_3_expt_grp = WT_expt_grp.subGroup(
        list(WT_dataframe[(WT_dataframe['X_condition'] == 'C')
                          & (WT_dataframe['X_day'] == '2') &
                          (WT_dataframe['X_session'] == '0')]['expt']))
    place.plotPositionHeatmap(WT_3_expt_grp,
                              roi_filter=WT_filter,
                              ax=WT_3_heatmap_ax,
                              norm='individual',
                              cbar_visible=True,
                              cax=WT_colorbar_ax,
                              cmap=WT_cmap,
                              plotting_order='place_cells_only',
                              show_belt=False,
                              reward_in_middle=True)
    fix_heatmap_ax(WT_3_heatmap_ax, WT_3_expt_grp)
    WT_3_heatmap_ax.set_title(r'Condition $\mathrm{III}$: Day 3')
    WT_3_heatmap_ax.set_ylabel('')
    WT_3_heatmap_ax.set_xlabel('')
    WT_colorbar_ax.set_yticklabels(['Min', 'Max'])

    Df_cmap = sns.light_palette(Df_color, as_cmap=True)
    Df_dataframe = lab.ExperimentGroup.dataframe(
        Df_expt_grp, include_columns=['X_condition', 'X_day', 'X_session'])

    Df_1_expt_grp = Df_expt_grp.subGroup(
        list(Df_dataframe[(Df_dataframe['X_condition'] == 'C')
                          & (Df_dataframe['X_day'] == '0') &
                          (Df_dataframe['X_session'] == '2')]['expt']))
    place.plotPositionHeatmap(Df_1_expt_grp,
                              roi_filter=Df_filter,
                              ax=Df_1_heatmap_ax,
                              norm='individual',
                              cbar_visible=False,
                              cmap=Df_cmap,
                              plotting_order='place_cells_only',
                              show_belt=False,
                              reward_in_middle=True)
    fix_heatmap_ax(Df_1_heatmap_ax, Df_1_expt_grp)
    Df_1_heatmap_ax.set_ylabel(Df_label)

    Df_3_expt_grp = Df_expt_grp.subGroup(
        list(Df_dataframe[(Df_dataframe['X_condition'] == 'C')
                          & (Df_dataframe['X_day'] == '2') &
                          (Df_dataframe['X_session'] == '0')]['expt']))
    place.plotPositionHeatmap(Df_3_expt_grp,
                              roi_filter=Df_filter,
                              ax=Df_3_heatmap_ax,
                              norm='individual',
                              cbar_visible=True,
                              cax=Df_colorbar_ax,
                              cmap=Df_cmap,
                              plotting_order='place_cells_only',
                              show_belt=False,
                              reward_in_middle=True)
    fix_heatmap_ax(Df_3_heatmap_ax, Df_3_expt_grp)
    Df_3_heatmap_ax.set_ylabel('')
    Df_colorbar_ax.set_yticklabels(['Min', 'Max'])

    #
    # Fraction of PCs near reward
    #

    activity_metric = place.centroid_to_position_threshold
    activity_kwargs = {
        'method': 'resultant_vector',
        'positions': 'reward',
        'pcs_only': True,
        'threshold': np.pi / 8
    }
    behavior_fn = ra.fraction_licks_in_reward_zone
    behavior_kwargs = {}
    behavior_label = 'Fraction of licks in reward zone'

    plotting.plot_metric(pf_close_fraction_ax,
                         expt_grps,
                         metric_fn=activity_metric,
                         roi_filters=roi_filters,
                         groupby=[['expt', 'X_condition', 'X_day']],
                         plotby=['X_condition', 'X_day'],
                         plot_abs=False,
                         plot_method='line',
                         activity_kwargs=activity_kwargs,
                         rotate_labels=False,
                         activity_label='Fraction of place cells near reward',
                         label_every_n=1,
                         colors=colors,
                         markers=markers,
                         markersize=5,
                         return_full_dataframes=False,
                         linestyles=linestyles)
    pf_close_fraction_ax.axhline(1 / 8., linestyle='--', color='k')
    pf_close_fraction_ax.set_title('')
    sns.despine(ax=pf_close_fraction_ax)
    pf_close_fraction_ax.set_xlabel('Day in Condition')
    day_number_only_label(pf_close_fraction_ax)
    label_conditions(pf_close_fraction_ax)
    pf_close_fraction_ax.legend(loc='upper left', fontsize=6)
    pf_close_fraction_ax.set_ylim(0, 0.40)
    pf_close_fraction_ax.set_yticks([0, 0.1, 0.2, 0.3, 0.4])

    scatter_kws = {'s': 5}
    colorby_list = [(expt_grp.label(), 'C') for expt_grp in expt_grps]
    pf_close_behav_corr_ax.set_xlim(frac_near_range_2)
    pf_close_behav_corr_ax.set_ylim(behav_range_2)
    plotting.plot_paired_metrics(
        expt_grps,
        first_metric_fn=place.centroid_to_position_threshold,
        second_metric_fn=behavior_fn,
        roi_filters=roi_filters,
        groupby=(('expt', ), ),
        colorby=('expt_grp', 'X_condition'),
        filter_fn=lambda df: df['X_condition'] == 'C',
        filter_columns=['X_condition'],
        first_metric_kwargs=activity_kwargs,
        second_metric_kwargs=behavior_kwargs,
        first_metric_label='Fraction of place cells near reward',
        second_metric_label=behavior_label,
        shuffle_colors=False,
        fit_reg=True,
        plot_method='regplot',
        colorby_list=colorby_list,
        colors=colors,
        markers=markers,
        ax=pf_close_behav_corr_ax,
        scatter_kws=scatter_kws,
        truncate=False,
        linestyles=linestyles)
    pf_close_behav_corr_ax.set_xlim(frac_near_range_2)
    pf_close_behav_corr_ax.set_ylim(behav_range_2)
    pf_close_behav_corr_ax.tick_params(direction='in')
    pf_close_behav_corr_ax.get_legend().set_visible(False)
    pf_close_behav_corr_ax.legend(loc='upper left', fontsize=6)

    misc.save_figure(fig, filename, save_dir=save_dir)

    plt.close('all')
def main():
    hidden_grps = df.loadExptGrps('GOL')

    WT_expt_grp_hidden = hidden_grps['WT_place_set']
    Df_expt_grp_hidden = hidden_grps['Df_place_set']
    expt_grps_hidden = [WT_expt_grp_hidden, Df_expt_grp_hidden]

    acute_grps = df.loadExptGrps('RF')

    WT_expt_grp_acute = acute_grps['WT_place_set'].unpair()
    Df_expt_grp_acute = acute_grps['Df_place_set'].unpair()
    expt_grps_acute = [WT_expt_grp_acute, Df_expt_grp_acute]

    WT_label = WT_expt_grp_hidden.label()
    Df_label = Df_expt_grp_hidden.label()
    labels = [WT_label, Df_label]

    fig = plt.figure(figsize=(8.5, 11))

    gs1 = plt.GridSpec(1, 1, top=0.9, bottom=0.7, left=0.1, right=0.20)
    across_ctx_ax = fig.add_subplot(gs1[0, 0])

    gs2 = plt.GridSpec(3, 1, top=0.9, bottom=0.7, left=0.25, right=0.35)
    wt_pie_ax = fig.add_subplot(gs2[0, 0])
    df_pie_ax = fig.add_subplot(gs2[1, 0])
    shuffle_pie_ax = fig.add_subplot(gs2[2, 0])
    pie_axs = (wt_pie_ax, df_pie_ax, shuffle_pie_ax)

    gs3 = plt.GridSpec(1, 1, top=0.9, bottom=0.7, left=0.4, right=0.5)
    cue_cell_bar_ax = fig.add_subplot(gs3[0, 0])

    gs5 = plt.GridSpec(1, 1, top=0.5, bottom=0.3, left=0.1, right=0.3)
    acute_stability_ax = fig.add_subplot(gs5[0, 0])

    acute_stability_inset_ax = fig.add_axes([0.23, 0.32, 0.05, 0.08])

    gs6 = plt.GridSpec(1, 1, top=0.5, bottom=0.3, left=0.4, right=0.5)
    task_compare_ax = fig.add_subplot(gs6[0, 0])

    #
    # RF Compare
    #
    params = {}
    params['filename'] = filename

    params_cent_shift_pc = {}
    params_cent_shift_pc['stability_fn'] = place.activity_centroid_shift
    params_cent_shift_pc['stability_kwargs'] = {
        'activity_filter': 'pc_both',
        'circ_var_pcs': False,
        'units': 'norm',
        'shuffle': True
    }
    params_cent_shift_pc['stability_label'] = \
        'Centroid shift (fraction of belt)'

    params_cent_shift_all = {}
    params_cent_shift_all['stability_fn'] = place.activity_centroid_shift
    params_cent_shift_all['stability_kwargs'] = {
        'activity_filter': 'active_both',
        'circ_var_pcs': False,
        'units': 'norm',
        'shuffle': True
    }
    params_cent_shift_all['stability_label'] = \
        'Centroid shift (fraction of belt)'
    params_cent_shift_all['stability_inset_ylim'] = (0.15, 0.30)
    params_cent_shift_all['stability_cdf_range'] = (0.15, 0.35)
    params_cent_shift_all['stability_cdf_ticks'] = \
        (0.15, 0.20, 0.25, 0.30, 0.35)
    params_cent_shift_all['stability_compare_ylim'] = (0.15, 0.27)
    params_cent_shift_all['stability_compare_yticks'] = (0.15, 0.20, 0.25)
    params_cent_shift_all['ctx_compare_ylim'] = (0.10, 0.30)
    params_cent_shift_all['ctx_compare_yticks'] = \
        (0.10, 0.15, 0.20, 0.25, 0.30)

    params_cent_shift_cm = {}
    params_cent_shift_cm['stability_fn'] = place.activity_centroid_shift
    params_cent_shift_cm['stability_kwargs'] = {
        'activity_filter': 'active_both',
        'circ_var_pcs': False,
        'units': 'cm',
        'shuffle': True
    }
    params_cent_shift_cm['stability_label'] = 'Centroid shift (cm)'

    params_pop_vect_corr = {}
    params_pop_vect_corr['stability_fn'] = place.population_vector_correlation
    params_pop_vect_corr['stability_kwargs'] = {
        'method': 'corr',
        'activity_filter': 'pc_both',
        'min_pf_density': 0.05,
        'circ_var_pcs': False
    }
    params_pop_vect_corr['stability_label'] = 'Population vector correlation'

    params_pf_corr = {}
    params_pf_corr['stability_fn'] = place.place_field_correlation
    params_pf_corr['stability_kwargs'] = {'activity_filter': 'pc_either'}
    params_pf_corr['stability_label'] = 'Place field correlation'
    params_pf_corr['stability_inset_ylim'] = (0, 0.50)
    params_pf_corr['stability_cdf_range'] = (0.15, 0.55)
    params_pf_corr['stability_cdf_ticks'] = (0.15, 0.25, 0.35, 0.45, 0.55)
    params_pf_corr['stability_compare_ylim'] = (0.22, 0.40)
    params_pf_corr['stability_compare_yticks'] = (0.25, 0.30, 0.35, 0.40)
    params_pf_corr['hidden_ctx_compare_ylim'] = (0.22, 0.40)
    params_pf_corr['hidden_ctx_compare_yticks'] = (0.25, 0.30, 0.35, 0.40)
    params_pf_corr['ctx_compare_ylim'] = (0.22, 0.40)
    params_pf_corr['ctx_compare_yticks'] = (0.25, 0.30, 0.35, 0.40)

    params.update(params_cent_shift_all)

    day_paired_grps_acute = [
        grp.pair('consecutive groups', groupby=['day_in_df'])
        for grp in expt_grps_acute
    ]
    paired_grps_acute = day_paired_grps_acute
    paired_grps_hidden = [
        grp.pair('consecutive groups', groupby=['X_condition', 'X_day'])
        for grp in expt_grps_hidden
    ]

    filter_fn = lambda df: (df['expt_pair_label'] == 'SameAll')
    filter_columns = ['expt_pair_label']

    acute_stability = plotting.plot_metric(
        acute_stability_ax,
        paired_grps_acute,
        metric_fn=params['stability_fn'],
        groupby=[['expt_pair_label', 'second_expt']],
        plotby=None,
        plot_method='cdf',
        plot_abs=True,
        roi_filters=roi_filters,
        activity_kwargs=params['stability_kwargs'],
        plot_shuffle=True,
        shuffle_plotby=False,
        pool_shuffle=True,
        activity_label=params['stability_label'],
        colors=colors,
        rotate_labels=False,
        filter_fn=filter_fn,
        filter_columns=filter_columns,
        return_full_dataframes=False,
        linestyles=linestyles)
    acute_stability_ax.set_xlabel(params['stability_label'])
    acute_stability_ax.set_title('')
    sns.despine(ax=acute_stability_ax)
    acute_stability_ax.set_xlim(params['stability_cdf_range'])
    acute_stability_ax.set_xticks(params['stability_cdf_ticks'])
    acute_stability_ax.legend(loc='upper left', fontsize=6)

    plotting.plot_metric(acute_stability_inset_ax,
                         paired_grps_acute,
                         metric_fn=params['stability_fn'],
                         groupby=[['second_expt'], ['second_mouseID']],
                         plotby=None,
                         plot_method='swarm',
                         plot_abs=True,
                         roi_filters=roi_filters,
                         activity_kwargs=params['stability_kwargs'],
                         plot_shuffle=True,
                         shuffle_plotby=False,
                         pool_shuffle=True,
                         activity_label=params['stability_label'],
                         colors=colors,
                         rotate_labels=False,
                         filter_fn=filter_fn,
                         filter_columns=filter_columns,
                         linewidth=0.2,
                         edgecolor='gray',
                         plot_shuffle_as_hline=True)
    acute_stability_inset_ax.get_legend().set_visible(False)
    sns.despine(ax=acute_stability_inset_ax)
    acute_stability_inset_ax.set_title('')
    acute_stability_inset_ax.set_ylabel('')
    acute_stability_inset_ax.set_xlabel('')
    acute_stability_inset_ax.tick_params(bottom=False, labelbottom=False)
    acute_stability_inset_ax.set_ylim(params['stability_inset_ylim'])
    acute_stability_inset_ax.set_yticks(params['stability_inset_ylim'])

    tmp_fig = plt.figure()
    tmp_ax = tmp_fig.add_subplot(111)
    hidden_stability = plotting.plot_metric(
        tmp_ax,
        paired_grps_hidden,
        metric_fn=params['stability_fn'],
        groupby=[['expt_pair_label', 'second_expt']],
        plotby=('expt_pair_label', ),
        plot_method='line',
        plot_abs=True,
        roi_filters=roi_filters,
        activity_kwargs=params['stability_kwargs'],
        plot_shuffle=True,
        shuffle_plotby=False,
        pool_shuffle=True,
        activity_label=params['stability_label'],
        colors=colors,
        rotate_labels=False,
        filter_fn=filter_fn,
        filter_columns=filter_columns,
        return_full_dataframes=False)
    plt.close(tmp_fig)

    wt_acute = acute_stability[WT_label]['dataframe']
    wt_acute_shuffle = acute_stability[WT_label]['shuffle']
    df_acute = acute_stability[Df_label]['dataframe']
    df_acute_shuffle = acute_stability[Df_label]['shuffle']

    wt_hidden = hidden_stability[WT_label]['dataframe']
    wt_hidden_shuffle = hidden_stability[WT_label]['shuffle']
    df_hidden = hidden_stability[Df_label]['dataframe']
    df_hidden_shuffle = hidden_stability[Df_label]['shuffle']

    for dataframe in (wt_acute, wt_acute_shuffle, df_acute, df_acute_shuffle):
        dataframe['task'] = 'RF'

    for dataframe in (wt_hidden, wt_hidden_shuffle, df_hidden,
                      df_hidden_shuffle):
        dataframe['task'] = 'GOL'

    WT_data = wt_acute.append(wt_hidden, ignore_index=True)
    Df_data = df_acute.append(df_hidden, ignore_index=True)

    WT_shuffle = wt_acute_shuffle.append(wt_hidden_shuffle, ignore_index=True)
    Df_shuffle = df_acute_shuffle.append(df_hidden_shuffle, ignore_index=True)

    filter_columns = ('expt_pair_label', )
    filter_fn = lambda df: (df['expt_pair_label'] == 'SameAll')

    order_dict = {'RF': 0, 'GOL': 1}
    WT_data['order'] = WT_data['task'].map(order_dict)
    Df_data['order'] = Df_data['task'].map(order_dict)
    line_kwargs = {'markersize': 4}
    plotting.plot_dataframe(task_compare_ax, [WT_data, Df_data],
                            [WT_shuffle, Df_shuffle],
                            labels=labels,
                            activity_label='',
                            groupby=[['task', 'second_mouseID']],
                            plotby=('task', ),
                            plot_method='box_and_line',
                            colors=colors,
                            filter_fn=filter_fn,
                            filter_columns=filter_columns,
                            plot_shuffle=True,
                            shuffle_plotby=False,
                            pool_shuffle=True,
                            orderby='order',
                            notch=False,
                            plot_shuffle_as_hline=True,
                            markers=markers,
                            linestyles=linestyles,
                            line_kwargs=line_kwargs,
                            flierprops={
                                'markersize': 3,
                                'marker': 'o'
                            },
                            whis='range')
    task_compare_ax.set_title('')
    sns.despine(ax=task_compare_ax)
    task_compare_ax.set_ylim(params['stability_compare_ylim'])
    task_compare_ax.set_yticks(params['stability_compare_yticks'])
    task_compare_ax.set_xlabel('')
    task_compare_ax.set_ylabel(params['stability_label'])
    task_compare_ax.legend(loc='upper right', fontsize=6)

    #
    # Stability across transition
    #
    groupby = [['second_expt'], ['second_mouse']]
    filter_fn = lambda df: (df['X_first_condition'] == 'A') \
        & (df['X_second_condition'] == 'B')
    filter_columns = ('X_first_condition', 'X_second_condition')
    plotting.plot_metric(across_ctx_ax,
                         paired_grps_hidden,
                         metric_fn=params['stability_fn'],
                         groupby=groupby,
                         plotby=None,
                         plot_method='swarm',
                         activity_kwargs=params['stability_kwargs'],
                         plot_shuffle=True,
                         shuffle_plotby=False,
                         pool_shuffle=True,
                         colors=colors,
                         activity_label=params['stability_label'],
                         rotate_labels=False,
                         filter_fn=filter_fn,
                         filter_columns=filter_columns,
                         plot_shuffle_as_hline=True,
                         return_full_dataframes=False,
                         plot_bar=True,
                         roi_filters=roi_filters)
    sns.despine(ax=across_ctx_ax)
    across_ctx_ax.set_ylim(0.0, 0.3)
    across_ctx_ax.set_yticks([0.0, 0.1, 0.2, 0.3])
    across_ctx_ax.set_xticklabels([])
    across_ctx_ax.set_xlabel('')
    across_ctx_ax.set_title('')
    across_ctx_ax.get_legend().set_visible(False)
    plotting.stackedText(across_ctx_ax, labels, colors=colors, loc=2, size=10)

    #
    # Cue remapping
    #

    THRESHOLD = 0.05 * 2 * np.pi
    CUENESS_THRESHOLD = 0.33

    def first_cue_position(row):
        expt = row['first_expt']
        cue = row['cue']
        cues = expt.belt().cues(normalized=True)
        first_cue = cues.ix[cues['cue'] == cue]
        pos = (first_cue['start'] + first_cue['stop']) / 2
        angle = pos * 2 * np.pi
        return np.complex(np.cos(angle), np.sin(angle))

    def dotproduct(v1, v2):
        return sum((a * b) for a, b in zip(v1, v2))

    def length(v):
        return math.sqrt(dotproduct(v, v))

    def angle(v1, v2):
        return math.acos(
            np.round(dotproduct(v1, v2) / (length(v1) * length(v2)), 3))

    def distance_to_first_cue(row):
        centroid = row['second_centroid']
        pos = row['first_cue_position']
        return angle((pos.real, pos.imag), (centroid.real, centroid.imag))

    WT_copy = copy(WT_expt_grp_hidden)
    WT_copy.filterby(lambda df: ~df['X_condition'].str.contains('C'),
                     ['X_condition'])
    WT_paired = WT_copy.pair('consecutive groups',
                             groupby=['X_condition',
                                      'X_day']).pair('consecutive groups',
                                                     groupby=['X_condition'])

    Df_copy = copy(Df_expt_grp_hidden)
    Df_copy.filterby(lambda df: ~df['X_condition'].str.contains('C'),
                     ['X_condition'])
    Df_paired = Df_copy.pair('consecutive groups',
                             groupby=['X_condition',
                                      'X_day']).pair('consecutive groups',
                                                     groupby=['X_condition'])

    WT_df, WT_shuffle_df = place.cue_cell_remapping(
        WT_paired,
        roi_filter=WT_filter,
        near_threshold=THRESHOLD,
        activity_filter='active_both',
        circ_var_pcs=False,
        shuffle=True)
    Df_df, Df_shuffle_df = place.cue_cell_remapping(
        Df_paired,
        roi_filter=Df_filter,
        near_threshold=THRESHOLD,
        activity_filter='active_both',
        circ_var_pcs=False,
        shuffle=True)

    shuffle_df = pd.concat([WT_shuffle_df, Df_shuffle_df], ignore_index=True)

    cueness, cueness_fraction = [], []
    cue_n, place_n, neither_n = [], [], []

    for grp_df in (WT_df, Df_df, shuffle_df):

        grp_df['first_cue_position'] = grp_df.apply(first_cue_position, axis=1)

        grp_df['second_distance_to_first_cue_position'] = grp_df.apply(
            distance_to_first_cue, axis=1)

        grp_df['cueness'] = grp_df['second_distance_to_first_cue_position'] / \
            (grp_df['value'] + grp_df['second_distance_to_first_cue_position'])

        plotting.prepare_dataframe(grp_df, ['first_mouse'])
        cueness_fraction.append([[]])
        cue_n.append([])
        place_n.append([])
        neither_n.append([])

        for mouse, mouse_df in grp_df.groupby('first_mouse'):
            cue_n[-1].append((mouse_df['cueness'] >
                              (1 - CUENESS_THRESHOLD)).sum())
            place_n[-1].append((mouse_df['cueness'] < CUENESS_THRESHOLD).sum())
            neither_n[-1].append(mouse_df.shape[0] - cue_n[-1][-1] -
                                 place_n[-1][-1])
            cueness_fraction[-1][0].append(cue_n[-1][-1] /
                                           float(place_n[-1][-1]))
        cueness.append([grp_df['cueness']])

    cue_labels = labels + ['shuffle']

    plotting.swarm_plot(cue_cell_bar_ax,
                        cueness_fraction[:2],
                        condition_labels=labels,
                        colors=colors,
                        plot_bar=True)
    cue_cell_bar_ax.axhline(np.mean(cueness_fraction[-1][0]),
                            ls='--',
                            color='k')
    sns.despine(ax=cue_cell_bar_ax)
    cue_cell_bar_ax.set_ylim(0, 1.5)
    cue_cell_bar_ax.set_yticks([0, 0.5, 1.0, 1.5])
    cue_cell_bar_ax.set_xticklabels([])
    cue_cell_bar_ax.set_xlabel('')
    cue_cell_bar_ax.set_ylabel('Cue-to-position ratio')
    cue_cell_bar_ax.get_legend().set_visible(False)
    plotting.stackedText(cue_cell_bar_ax,
                         labels,
                         colors=colors,
                         loc=2,
                         size=10)

    WT_colors = sns.light_palette(WT_color, 7)[:-6:-2]
    Df_colors = sns.light_palette(Df_color, 7)[:-6:-2]
    shuffle_colors = sns.light_palette('k', 7)[:-6:-2]
    pie_colors = (WT_colors, Df_colors, shuffle_colors)
    pie_labels = ['cue', 'position', 'neither']
    orig_size = mpl.rcParams.get('xtick.labelsize')
    mpl.rcParams['xtick.labelsize'] = 5
    for grp_ax, grp_label, grp_cue_n, grp_place_n, grp_neither_n, p_cs in zip(
            pie_axs, cue_labels, cue_n, place_n, neither_n, pie_colors):
        grp_ax.pie([sum(grp_cue_n),
                    sum(grp_place_n),
                    sum(grp_neither_n)],
                   autopct='%1.0f%%',
                   shadow=False,
                   frame=False,
                   labels=pie_labels,
                   colors=p_cs,
                   textprops={'fontsize': 5})
        grp_ax.set_title(grp_label)
        plotting.square_axis(grp_ax)
    mpl.rcParams['xtick.labelsize'] = orig_size

    misc.save_figure(fig, params['filename'], save_dir=save_dir)

    plt.close('all')
示例#5
0
def main():

    fig = plt.figure(figsize=(8.5, 11))

    gs1 = plt.GridSpec(2,
                       2,
                       left=0.1,
                       right=0.7,
                       top=0.9,
                       bottom=0.5,
                       hspace=0.4,
                       wspace=0.4)
    WT_enrich_ax = fig.add_subplot(gs1[0, 0])
    Df_enrich_ax = fig.add_subplot(gs1[0, 1])
    WT_final_dist_ax = fig.add_subplot(gs1[1, 0])
    Df_final_dist_ax = fig.add_subplot(gs1[1, 1])

    simulations_path_A = os.path.join(
        df.data_path, 'enrichment_model',
        'WT_Df_enrichment_model_simulation_A.pkl')
    simulations_path_B = os.path.join(
        df.data_path, 'enrichment_model',
        'WT_Df_enrichment_model_simulation_B.pkl')
    simulations_path_C = os.path.join(
        df.data_path, 'enrichment_model',
        'WT_Df_enrichment_model_simulation_C.pkl')

    m_A = pickle.load(open(simulations_path_A))
    m_B = pickle.load(open(simulations_path_B))
    m_C = pickle.load(open(simulations_path_C))

    WT_colors = sns.light_palette(WT_color, 7)[2::2]
    Df_colors = sns.light_palette(Df_color, 7)[2::2]

    condition_labels = [
        r'Condition $\mathrm{I}$', r'Condition $\mathrm{II}$',
        r'Condition $\mathrm{III}$'
    ]

    WT_final_dists, Df_final_dists = [], []

    for m, WT_c, Df_c in zip((m_A, m_B, m_C), WT_colors, Df_colors):

        WT_enrich = emp.calc_enrichment(m['WT_no_swap_pos'],
                                        m['WT_no_swap_masks'])
        Df_enrich = emp.calc_enrichment(m['Df_no_swap_pos'],
                                        m['Df_no_swap_masks'])

        WT_final_dists.append(
            emp.calc_final_distributions(m['WT_no_swap_pos'],
                                         m['WT_no_swap_masks']))
        Df_final_dists.append(
            emp.calc_final_distributions(m['Df_no_swap_pos'],
                                         m['Df_no_swap_masks']))

        emp.plot_enrichment(WT_enrich_ax, WT_enrich, WT_c, title='', rad=False)
        emp.plot_enrichment(Df_enrich_ax, Df_enrich, Df_c, title='', rad=False)

    WT_enrich_ax.set_xlabel("Iteration ('session' #)")
    Df_enrich_ax.set_xlabel("Iteration ('session' #)")
    plotting.stackedText(WT_enrich_ax,
                         condition_labels,
                         colors=WT_colors,
                         loc=2,
                         size=8)
    plotting.stackedText(Df_enrich_ax,
                         condition_labels,
                         colors=Df_colors,
                         loc=2,
                         size=8)

    emp.plot_final_distributions(WT_final_dist_ax,
                                 WT_final_dists,
                                 WT_colors,
                                 labels=condition_labels,
                                 title='',
                                 rad=False)
    emp.plot_final_distributions(Df_final_dist_ax,
                                 Df_final_dists,
                                 Df_colors,
                                 labels=condition_labels,
                                 title='',
                                 rad=False)

    WT_final_dist_ax.set_xlabel('Distance from reward\n(fraction of belt)')
    Df_final_dist_ax.set_xlabel('Distance from reward\n(fraction of belt)')
    plotting.stackedText(WT_final_dist_ax,
                         condition_labels,
                         colors=WT_colors,
                         loc=2,
                         size=8)
    plotting.stackedText(Df_final_dist_ax,
                         condition_labels,
                         colors=Df_colors,
                         loc=2,
                         size=8)
    WT_final_dist_ax.set_yticks([0, 0.1, 0.2, 0.3])
    Df_final_dist_ax.set_yticks([0, 0.1, 0.2, 0.3])

    save_figure(fig, filename, save_dir=save_dir)
示例#6
0
 def get_cmap(base_color, n_colors=256):
     colors = [np.array([1., 1., 1., 0])] + \
              sns.light_palette(base_color, n_colors=n_colors - 1)
     return mpl_colors.ListedColormap(colors)