if not os.path.isdir(args.jobdir): sys.exit('Error: directory "%s" does not exist' % args.pooldir)
if not os.path.exists(args.reffile): sys.exit('Error: reference file "%s" does not exist' % args.reffile)
job_path = os.path.abspath(args.jobdir)
reference_file = os.path.abspath(args.reffile)
# load sequences
seqs = dict( [(s.id,s) for s in SeqIO.parse(reference_file,'fasta')] )
summaries = dict(( (name,{'variants':[]}) for name in seqs.keys()))
''' GATK variants '''
print >>sys.stderr, "[ Reading GATK variants ]"
vlines = [l.strip('\n') for l in open('%s/GATK/snps.gatk.vcf' % job_path,'rU') if not l.startswith('#')]
for l in vlines:
v = Variant.from_vcf(l)
v.caller = 'gatk'
summaries[v.chrom]['variants'].append(v)
''' PacBio variants '''
print >>sys.stderr, "[ Reading GenCons variants ]"
glines = [l.strip('\n') for l in gzip.open('%s/data/variants.gff.gz' % job_path,'rb') if not l.startswith('#')]
for l in glines:
v = Variant.from_gff(l)
v.caller = 'gencons'
summaries[v.chrom]['variants'].append(v)
''' coverage variants '''
print >>sys.stderr, "[ Reading coverage variants ]"
covdata = parse_covdepth('%s/GATK/covdepth' % job_path)
covvars = {}
