def commit(self):
if self.currentGds:
self.error(0)
sample_type = None
self.progressBarInit(processEvents=None)
_, groups = self.selectedSamples()
if len(groups) == 1 and self.outputRows:
sample_type = groups[0]
self.setEnabled(False)
self.setBlocking(True)
progress = methodinvoke(self, "progressCompleted", (int, int))
def get_data(gds_id, report_genes, transpose, sample_type, title):
gds_ensure_downloaded(gds_id, progress)
gds = geo.GDS(gds_id)
data = gds.getdata(report_genes=report_genes,
transpose=transpose,
sample_type=sample_type)
data.name = title
return data
get_data = partial(get_data,
self.currentGds["dataset_id"],
report_genes=self.mergeSpots,
transpose=self.outputRows,
sample_type=sample_type,
title=self.datasetName
or self.currentGds["title"])
self._datatask = Task(function=get_data)
self._datatask.finished.connect(self._on_dataready)
self._executor.submit(self._datatask)
def fetch_network():
geneinfo = geneinfo_f.result()
ppidb = fetch_ppidb(source, db_taxid, progress)
return get_gene_network(ppidb, geneinfo, db_taxid, query_genes,
include_neighborhood=include_neighborhood,
min_score=min_score,
progress=methodinvoke(self, "set_progress", (float,)))
def commit(self):
if self.currentGds:
self.error(0)
sample_type = None
self.progressBarInit(processEvents=None)
_, groups = self.selectedSamples()
if len(groups) == 1 and self.outputRows:
sample_type = groups[0]
self.setEnabled(False)
self.setBlocking(True)
progress = methodinvoke(self, "progressCompleted", (int, int))
def get_data(gds_id, report_genes, transpose, sample_type, title):
gds_ensure_downloaded(gds_id, progress)
gds = geo.GDS(gds_id)
data = gds.getdata(
report_genes=report_genes, transpose=transpose,
sample_type=sample_type
)
data.name = title
return data
get_data = partial(
get_data, self.currentGds["dataset_id"],
report_genes=self.mergeSpots,
transpose=self.outputRows,
sample_type=sample_type,
title=self.datasetName or self.currentGds["title"]
)
self._datatask = Task(function=get_data)
self._datatask.finished.connect(self._on_dataready)
self._executor.submit(self._datatask)
def RetrieveFilesList(self):
self.progress.setRange(0, 3)
self.serverFiles = serverfiles.ServerFiles()
task = Task(function=partial(retrieveFilesList, methodinvoke(self.progress, "advance")))
task.resultReady.connect(self.SetFilesList)
task.exceptionReady.connect(self.HandleError)
self.executor.submit(task)
self.setEnabled(False)
def RetrieveFilesList(self):
self.retryButton.hide()
self.warning(0)
self.progress.setRange(0, 3)
task = Task(function=partial(retrieveFilesList, methodinvoke(self.progress, "advance")))
task.resultReady.connect(self.SetFilesList)
task.exceptionReady.connect(self.HandleError)
self.executor.submit(task)
self.setEnabled(False)
def RetrieveFilesList(self):
self.retryButton.hide()
self.warning(0)
self.progress.setRange(0, 3)
self.serverFiles = serverfiles.ServerFiles(access_code=self.accessCode)
task = Task(function=partial(retrieveFilesList, self.serverFiles,
self.domains,
methodinvoke(self.progress, "advance")))
task.resultReady.connect(self.SetFilesList)
task.exceptionReady.connect(self.HandleError)
self.executor.submit(task)
self.setEnabled(False)
def commit(self):
include_neighborhood = self.include_neighborhood
query_genes = self.query_genes()
source = SOURCES[self.network_source]
if source.score_filter:
min_score = self.min_score
assert source.name == "STRING"
min_score = min_score * 1000
else:
min_score = None
taxid = self.taxid
progress = methodinvoke(self, "advance")
if self.geneinfo is None:
self.geneinfo = self.executor.submit(fetch_ncbi_geneinfo, taxid,
progress)
geneinfo_f = self.geneinfo
taxmap = source.tax_mapping
db_taxid = taxmap.get(taxid, taxid)
if db_taxid is None:
raise ValueError("invalid taxid for this network")
def fetch_network():
geneinfo = geneinfo_f.result()
ppidb = fetch_ppidb(source, db_taxid, progress)
return get_gene_network(ppidb,
geneinfo,
db_taxid,
query_genes,
include_neighborhood=include_neighborhood,
min_score=min_score,
progress=methodinvoke(
self, "set_progress", (float, )))
self.nettask = Task(function=fetch_network)
self.nettask.finished.connect(self._on_result_ready)
self.executor.submit(self.nettask)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._invalidated = False
self._update_info()
def _initialize(self):
# First try to import slumber to see if we can even use the
# kegg module.
try:
import slumber
except ImportError:
QMessageBox.warning(self,
"'slumber' library required.",
'<p>Please install '
'<a href="http://pypi.python.org/pypi/slumber">slumber</a> '
'library to use KEGG Pathways widget.</p>'
)
self.infoLabel.setText(
'<p>Please install '
'<a href="http://pypi.python.org/pypi/slumber">slumber</a> '
'library to use KEGG Pathways widget.</p>'
)
self.error(0, "Missing slumber/requests library")
return
progress = methodinvoke(self, "setProgress", (float,))
def get_genome():
"""Return a KEGGGenome with the common org entries precached."""
genome = kegg.KEGGGenome()
essential = genome.essential_organisms()
common = genome.common_organisms()
# Remove duplicates of essential from common.
# (essential + common list as defined here will be used in the
# GUI.)
common = [c for c in common if c not in essential]
# TODO: Add option to specify additional organisms not
# in the common list.
keys = map(genome.org_code_to_entry_key, essential + common)
genome.pre_cache(keys, progress_callback=progress)
return (keys, genome)
self._genomeTask = task = Task(function=get_genome)
task.finished.connect(self._initializeOrganisms)
self.progressBarInit()
self._executor.submit(task)
def commit(self):
include_neighborhood = self.include_neighborhood
query_genes = self.query_genes()
source = SOURCES[self.network_source]
if source.score_filter:
min_score = self.min_score
assert source.name == "STRING"
min_score = min_score * 1000
else:
min_score = None
taxid = self.taxid
progress = methodinvoke(self, "advance")
if self.geneinfo is None:
self.geneinfo = self.executor.submit(
fetch_ncbi_geneinfo, taxid, progress
)
geneinfo_f = self.geneinfo
taxmap = source.tax_mapping
db_taxid = taxmap.get(taxid, taxid)
if db_taxid is None:
raise ValueError("invalid taxid for this network")
def fetch_network():
geneinfo = geneinfo_f.result()
ppidb = fetch_ppidb(source, db_taxid, progress)
return get_gene_network(ppidb, geneinfo, db_taxid, query_genes,
include_neighborhood=include_neighborhood,
min_score=min_score,
progress=methodinvoke(self, "set_progress", (float,)))
self.nettask = Task(function=fetch_network)
self.nettask.finished.connect(self._on_result_ready)
self.executor.submit(self.nettask)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._invalidated = False
self._update_info()
def updateInfoItems(self):
self.warning(0)
if not self.data:
return
genes = self.inputGenes()
if self.useAttr:
genes = [attr.name for attr in self.data.domain.attributes]
elif self.attributes:
attr = self.attributes[self.geneAttr]
genes = [str(ex[attr]) for ex in self.data
if not ex[attr].isSpecial()]
else:
genes = []
if not genes:
self.warning(0, "Could not extract genes from input dataset.")
self.warning(1)
org = self.organisms[min(self.organismIndex, len(self.organisms) - 1)]
source_name, info_getter = self.infoSource()
self.error(0)
self.updateDictyExpressLink(genes, show=org == "352472")
self.altSourceCheck.setVisible(org == "352472")
self.progressBarInit()
self.setBlocking(True)
self.setEnabled(False)
self.infoLabel.setText("Retrieving info records.\n")
self.genes = genes
task = Task(
function=partial(
info_getter, org, genes,
advance=methodinvoke(self, "advance", ()))
)
self.itemsfuture = self.executor.submit(task)
task.finished.connect(self._onItemsCompleted)
def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
OWWidget.__init__(self, parent, signalManager, name)
self.selectionChanged = False
self.filterString = ""
self.datasetName = ""
## GUI
box = gui.widgetBox(self.controlArea, "Info", addSpace=True)
self.infoBox = gui.widgetLabel(box, "Initializing\n\n")
box = gui.widgetBox(self.controlArea, "Output", addSpace=True)
gui.radioButtonsInBox(box,
self,
"outputRows",
["Genes in rows", "Samples in rows"],
"Rows",
callback=self.commitIf)
gui.checkBox(box,
self,
"mergeSpots",
"Merge spots of same gene",
callback=self.commitIf)
gui.separator(box)
self.nameEdit = gui.lineEdit(
box,
self,
"datasetName",
"Data set name",
tooltip="Override the default output data set name",
callback=self.onNameEdited)
self.nameEdit.setPlaceholderText("")
if sys.version_info < (3, ):
box = gui.widgetBox(self.controlArea, "Commit", addSpace=True)
self.commitButton = gui.button(box,
self,
"Commit",
callback=self.commit)
cb = gui.checkBox(box, self, "autoCommit", "Commit on any change")
gui.setStopper(self, self.commitButton, cb, "selectionChanged",
self.commit)
else:
gui.auto_commit(self.controlArea,
self,
"autoCommit",
"Commit",
box="Commit")
self.commitIf = self.commit
gui.rubber(self.controlArea)
gui.widgetLabel(self.mainArea, "Filter")
self.filterLineEdit = QLineEdit(textChanged=self.filter)
self.completer = TokenListCompleter(self,
caseSensitivity=Qt.CaseInsensitive)
self.filterLineEdit.setCompleter(self.completer)
self.mainArea.layout().addWidget(self.filterLineEdit)
splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(splitter)
self.treeWidget = QTreeView(splitter)
self.treeWidget.setSelectionMode(QTreeView.SingleSelection)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSortingEnabled(True)
self.treeWidget.setAlternatingRowColors(True)
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)
linkdelegate = LinkStyledItemDelegate(self.treeWidget)
self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
self.treeWidget.setItemDelegateForColumn(
0, gui.IndicatorItemDelegate(self.treeWidget, role=Qt.DisplayRole))
proxyModel = MySortFilterProxyModel(self.treeWidget)
self.treeWidget.setModel(proxyModel)
self.treeWidget.selectionModel().selectionChanged.connect(
self.updateSelection)
self.treeWidget.viewport().setMouseTracking(True)
splitterH = QSplitter(Qt.Horizontal, splitter)
box = gui.widgetBox(splitterH, "Description")
self.infoGDS = gui.widgetLabel(box, "")
self.infoGDS.setWordWrap(True)
gui.rubber(box)
box = gui.widgetBox(splitterH, "Sample Annotations")
self.annotationsTree = QTreeWidget(box)
self.annotationsTree.setHeaderLabels(
["Type (Sample annotations)", "Sample count"])
self.annotationsTree.setRootIsDecorated(True)
box.layout().addWidget(self.annotationsTree)
self.annotationsTree.itemChanged.connect(
self.annotationSelectionChanged)
self._annotationsUpdating = False
self.splitters = splitter, splitterH
for sp, setting in zip(self.splitters, self.splitterSettings):
sp.splitterMoved.connect(self.splitterMoved)
sp.restoreState(setting)
self.searchKeys = [
"dataset_id", "title", "platform_organism", "description"
]
self.gds = []
self.gds_info = None
self.resize(1000, 600)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._executor = ThreadExecutor()
func = partial(get_gds_model,
methodinvoke(self, "_setProgress", (float, )))
self._inittask = Task(function=func)
self._inittask.finished.connect(self._initializemodel)
self._executor.submit(self._inittask)
self._datatask = None
def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
OWWidget.__init__(self, parent, signalManager, name)
self.outputs = [("Expression Data", ExampleTable)]
## Settings
self.selectedAnnotation = 0
self.includeIf = False
self.minSamples = 3
self.autoCommit = False
self.outputRows = 0
self.mergeSpots = True
self.filterString = ""
self.currentGds = None
self.selectionChanged = False
self.autoCommit = False
self.gdsSelectionStates = {}
self.splitterSettings = [
'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xea\x00\x00\x00\xd7\x01\x00\x00\x00\x07\x01\x00\x00\x00\x02',
'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xb5\x00\x00\x02\x10\x01\x00\x00\x00\x07\x01\x00\x00\x00\x01'
]
self.datasetNames = {}
self.loadSettings()
self.datasetName = ""
## GUI
self.infoBox = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"Initializing\n\n"
)
box = OWGUI.widgetBox(self.controlArea, "Output", addSpace=True)
OWGUI.radioButtonsInBox(box, self, "outputRows",
["Genes or spots", "Samples"], "Rows",
callback=self.commitIf)
OWGUI.checkBox(box, self, "mergeSpots", "Merge spots of same gene",
callback=self.commitIf)
OWGUI.separator(box)
self.nameEdit = OWGUI.lineEdit(
box, self, "datasetName", "Data set name",
tooltip="Override the default output data set name",
callback=self.onNameEdited
)
self.nameEdit.setPlaceholderText("")
box = OWGUI.widgetBox(self.controlArea, "Commit", addSpace=True)
self.commitButton = OWGUI.button(box, self, "Commit",
callback=self.commit)
cb = OWGUI.checkBox(box, self, "autoCommit", "Commit on any change")
OWGUI.setStopper(self, self.commitButton, cb, "selectionChanged",
self.commit)
OWGUI.rubber(self.controlArea)
self.filterLineEdit = OWGUIEx.lineEditHint(
self.mainArea, self, "filterString", "Filter",
caseSensitive=False, matchAnywhere=True,
callback=self.filter, delimiters=" ")
splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(splitter)
self.treeWidget = QTreeView(splitter)
self.treeWidget.setSelectionMode(QAbstractItemView.SingleSelection)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSortingEnabled(True)
self.treeWidget.setAlternatingRowColors(True)
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)
linkdelegate = LinkStyledItemDelegate(self.treeWidget)
self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
self.treeWidget.setItemDelegateForColumn(
0, OWGUI.IndicatorItemDelegate(self.treeWidget,
role=Qt.DisplayRole))
proxyModel = MySortFilterProxyModel(self.treeWidget)
self.treeWidget.setModel(proxyModel)
self.treeWidget.selectionModel().selectionChanged.connect(
self.updateSelection
)
self.treeWidget.viewport().setMouseTracking(True)
splitterH = QSplitter(Qt.Horizontal, splitter)
box = OWGUI.widgetBox(splitterH, "Description")
self.infoGDS = OWGUI.widgetLabel(box, "")
self.infoGDS.setWordWrap(True)
OWGUI.rubber(box)
box = OWGUI.widgetBox(splitterH, "Sample Annotations")
self.annotationsTree = QTreeWidget(box)
self.annotationsTree.setHeaderLabels(
["Type (Sample annotations)", "Sample count"]
)
self.annotationsTree.setRootIsDecorated(True)
box.layout().addWidget(self.annotationsTree)
self.annotationsTree.itemChanged.connect(
self.annotationSelectionChanged
)
self._annotationsUpdating = False
self.splitters = splitter, splitterH
for sp, setting in zip(self.splitters, self.splitterSettings):
sp.splitterMoved.connect(self.splitterMoved)
sp.restoreState(setting)
self.searchKeys = ["dataset_id", "title", "platform_organism",
"description"]
self.gds = []
self.gds_info = None
self.resize(1000, 600)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._executor = ThreadExecutor()
func = partial(get_gds_model,
methodinvoke(self, "_setProgress", (float,)))
self._inittask = Task(function=func)
self._inittask.finished.connect(self._initializemodel)
self._executor.submit(self._inittask)
self._datatask = None
def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
OWWidget.__init__(self, parent, signalManager, name)
self.selectionChanged = False
self.filterString = ""
self.datasetName = ""
## GUI
box = gui.widgetBox(self.controlArea, "Info", addSpace=True)
self.infoBox = gui.widgetLabel(box, "Initializing\n\n")
box = gui.widgetBox(self.controlArea, "Output", addSpace=True)
gui.radioButtonsInBox(box, self, "outputRows",
["Genes in rows", "Samples in rows"], "Rows",
callback=self.commitIf)
gui.checkBox(box, self, "mergeSpots", "Merge spots of same gene",
callback=self.commitIf)
gui.separator(box)
self.nameEdit = gui.lineEdit(
box, self, "datasetName", "Data set name",
tooltip="Override the default output data set name",
callback=self.onNameEdited
)
self.nameEdit.setPlaceholderText("")
if sys.version_info < (3, ):
box = gui.widgetBox(self.controlArea, "Commit", addSpace=True)
self.commitButton = gui.button(
box, self, "Commit", callback=self.commit)
cb = gui.checkBox(box, self, "autoCommit", "Commit on any change")
gui.setStopper(self, self.commitButton, cb, "selectionChanged",
self.commit)
else:
gui.auto_commit(self.controlArea, self, "autoCommit", "Commit",
box="Commit")
self.commitIf = self.commit
gui.rubber(self.controlArea)
gui.widgetLabel(self.mainArea, "Filter")
self.filterLineEdit = QLineEdit(
textChanged=self.filter
)
self.completer = TokenListCompleter(
self, caseSensitivity=Qt.CaseInsensitive
)
self.filterLineEdit.setCompleter(self.completer)
self.mainArea.layout().addWidget(self.filterLineEdit)
splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(splitter)
self.treeWidget = QTreeView(splitter)
self.treeWidget.setSelectionMode(QTreeView.SingleSelection)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSortingEnabled(True)
self.treeWidget.setAlternatingRowColors(True)
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)
linkdelegate = LinkStyledItemDelegate(self.treeWidget)
self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
self.treeWidget.setItemDelegateForColumn(
0, gui.IndicatorItemDelegate(self.treeWidget,
role=Qt.DisplayRole))
proxyModel = MySortFilterProxyModel(self.treeWidget)
self.treeWidget.setModel(proxyModel)
self.treeWidget.selectionModel().selectionChanged.connect(
self.updateSelection
)
self.treeWidget.viewport().setMouseTracking(True)
splitterH = QSplitter(Qt.Horizontal, splitter)
box = gui.widgetBox(splitterH, "Description")
self.infoGDS = gui.widgetLabel(box, "")
self.infoGDS.setWordWrap(True)
gui.rubber(box)
box = gui.widgetBox(splitterH, "Sample Annotations")
self.annotationsTree = QTreeWidget(box)
self.annotationsTree.setHeaderLabels(
["Type (Sample annotations)", "Sample count"]
)
self.annotationsTree.setRootIsDecorated(True)
box.layout().addWidget(self.annotationsTree)
self.annotationsTree.itemChanged.connect(
self.annotationSelectionChanged
)
self._annotationsUpdating = False
self.splitters = splitter, splitterH
for sp, setting in zip(self.splitters, self.splitterSettings):
sp.splitterMoved.connect(self.splitterMoved)
sp.restoreState(setting)
self.searchKeys = ["dataset_id", "title", "platform_organism",
"description"]
self.gds = []
self.gds_info = None
self.resize(1000, 600)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._executor = ThreadExecutor()
func = partial(get_gds_model,
methodinvoke(self, "_setProgress", (float,)))
self._inittask = Task(function=func)
self._inittask.finished.connect(self._initializemodel)
self._executor.submit(self._inittask)
self._datatask = None
def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
OWWidget.__init__(self, parent, signalManager, name)
self.outputs = [("Expression Data", ExampleTable)]
## Settings
self.selectedAnnotation = 0
self.includeIf = False
self.minSamples = 3
self.autoCommit = False
self.outputRows = 1
self.mergeSpots = True
self.filterString = ""
self.currentGds = None
self.selectionChanged = False
self.autoCommit = False
self.gdsSelectionStates = {}
self.splitterSettings = [
'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xea\x00\x00\x00\xd7\x01\x00\x00\x00\x07\x01\x00\x00\x00\x02',
'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xb5\x00\x00\x02\x10\x01\x00\x00\x00\x07\x01\x00\x00\x00\x01'
]
self.datasetNames = {}
self.loadSettings()
self.datasetName = ""
## GUI
self.infoBox = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"Initializing\n\n"
)
box = OWGUI.widgetBox(self.controlArea, "Output", addSpace=True)
OWGUI.radioButtonsInBox(box, self, "outputRows",
["Genes in rows", "Samples in rows"], "Rows",
callback=self.commitIf)
OWGUI.checkBox(box, self, "mergeSpots", "Merge spots of same gene",
callback=self.commitIf)
OWGUI.separator(box)
self.nameEdit = OWGUI.lineEdit(
box, self, "datasetName", "Data set name",
tooltip="Override the default output data set name",
callback=self.onNameEdited
)
self.nameEdit.setPlaceholderText("")
box = OWGUI.widgetBox(self.controlArea, "Commit", addSpace=True)
self.commitButton = OWGUI.button(box, self, "Commit",
callback=self.commit)
cb = OWGUI.checkBox(box, self, "autoCommit", "Commit on any change")
OWGUI.setStopper(self, self.commitButton, cb, "selectionChanged",
self.commit)
OWGUI.rubber(self.controlArea)
self.filterLineEdit = OWGUIEx.lineEditHint(
self.mainArea, self, "filterString", "Filter",
caseSensitive=False, matchAnywhere=True,
callback=self.filter, delimiters=" ")
splitter = QSplitter(Qt.Vertical, self.mainArea)
self.mainArea.layout().addWidget(splitter)
self.treeWidget = QTreeView(splitter)
self.treeWidget.setSelectionMode(QAbstractItemView.SingleSelection)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSortingEnabled(True)
self.treeWidget.setAlternatingRowColors(True)
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)
linkdelegate = LinkStyledItemDelegate(self.treeWidget)
self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
self.treeWidget.setItemDelegateForColumn(
0, OWGUI.IndicatorItemDelegate(self.treeWidget,
role=Qt.DisplayRole))
proxyModel = MySortFilterProxyModel(self.treeWidget)
self.treeWidget.setModel(proxyModel)
self.treeWidget.selectionModel().selectionChanged.connect(
self.updateSelection
)
self.treeWidget.viewport().setMouseTracking(True)
splitterH = QSplitter(Qt.Horizontal, splitter)
box = OWGUI.widgetBox(splitterH, "Description")
self.infoGDS = OWGUI.widgetLabel(box, "")
self.infoGDS.setWordWrap(True)
OWGUI.rubber(box)
box = OWGUI.widgetBox(splitterH, "Sample Annotations")
self.annotationsTree = QTreeWidget(box)
self.annotationsTree.setHeaderLabels(
["Type (Sample annotations)", "Sample count"]
)
self.annotationsTree.setRootIsDecorated(True)
box.layout().addWidget(self.annotationsTree)
self.annotationsTree.itemChanged.connect(
self.annotationSelectionChanged
)
self._annotationsUpdating = False
self.splitters = splitter, splitterH
for sp, setting in zip(self.splitters, self.splitterSettings):
sp.splitterMoved.connect(self.splitterMoved)
sp.restoreState(setting)
self.searchKeys = ["dataset_id", "title", "platform_organism",
"description"]
self.gds = []
self.gds_info = None
self.resize(1000, 600)
self.setBlocking(True)
self.setEnabled(False)
self.progressBarInit()
self._executor = ThreadExecutor()
func = partial(get_gds_model,
methodinvoke(self, "_setProgress", (float,)))
self._inittask = Task(function=func)
self._inittask.finished.connect(self._initializemodel)
self._executor.submit(self._inittask)
self._datatask = None
def __init__(self, parent=None, signalManager=None, name="Gene Info"):
OWWidget.__init__(self, parent, signalManager, name)
self.inputs = [("Examples", Orange.data.Table, self.setData)]
self.outputs = [("Selected Examples", Orange.data.Table)]
self.organismIndex = 0
self.taxid = None
self.geneAttr = 0
self.useAttr = False
self.autoCommit = False
self.searchString = ""
self.selectionChangedFlag = False
self.useAltSource = 0
self.loadSettings()
self.__initialized = False
self.initfuture = None
self.itemsfuture = None
self.infoLabel = OWGUI.widgetLabel(
OWGUI.widgetBox(self.controlArea, "Info", addSpace=True),
"Initializing\n"
)
self.organisms = None
self.organismBox = OWGUI.widgetBox(
self.controlArea, "Organism", addSpace=True)
self.organismComboBox = OWGUI.comboBox(
self.organismBox, self, "organismIndex",
callback=self._onSelectedOrganismChanged,
debuggingEnabled=0)
# For now only support one alt source, with a checkbox
# In the future this can be extended to multiple selections
self.altSourceCheck = OWGUI.checkBox(self.organismBox, self,
"useAltSource", "Show information from dictyBase",
callback=self.onAltSourceChange,
# debuggingEnabled=0,
)
self.altSourceCheck.hide()
box = OWGUI.widgetBox(self.controlArea, "Gene names", addSpace=True)
self.geneAttrComboBox = OWGUI.comboBox(
box, self, "geneAttr",
"Gene atttibute", callback=self.updateInfoItems
)
OWGUI.checkBox(box, self, "useAttr", "Use attribute names",
callback=self.updateInfoItems,
disables=[(-1, self.geneAttrComboBox)])
self.geneAttrComboBox.setDisabled(bool(self.useAttr))
box = OWGUI.widgetBox(self.controlArea, "Commit", addSpace=True)
b = OWGUI.button(box, self, "Commit", callback=self.commit)
c = OWGUI.checkBox(box, self, "autoCommit", "Commit on change")
OWGUI.setStopper(self, b, c, "selectionChangedFlag",
callback=self.commit)
# A label for dictyExpress link
self.dictyExpressBox = OWGUI.widgetBox(
self.controlArea, "Dicty Express")
self.linkLabel = OWGUI.widgetLabel(self.dictyExpressBox, "")
self.linkLabel.setOpenExternalLinks(False)
self.connect(self.linkLabel, SIGNAL("linkActivated(QString)"),
self.onDictyExpressLink)
self.dictyExpressBox.hide()
OWGUI.rubber(self.controlArea)
OWGUI.lineEdit(self.mainArea, self, "searchString", "Filter",
callbackOnType=True, callback=self.searchUpdate)
self.treeWidget = QTreeView(self.mainArea)
self.treeWidget.setRootIsDecorated(False)
self.treeWidget.setSelectionMode(
QAbstractItemView.ExtendedSelection)
self.treeWidget.setItemDelegate(
LinkStyledItemDelegate(self.treeWidget))
self.treeWidget.setUniformRowHeights(True)
self.treeWidget.viewport().setMouseTracking(True)
self.treeWidget.setSortingEnabled(True)
self.mainArea.layout().addWidget(self.treeWidget)
box = OWGUI.widgetBox(self.mainArea, "",
orientation="horizontal")
OWGUI.button(box, self, "Select Filtered",
callback=self.selectFiltered)
OWGUI.button(box, self, "Clear Selection",
callback=self.treeWidget.clearSelection)
self.resize(1000, 700)
self.geneinfo = []
self.cells = []
self.row2geneinfo = {}
self.data = None
# : (# input genes, # matches genes)
self.matchedInfo = 0, 0
self.selectionUpdateInProgress = False
self.setBlocking(True)
self.executor = ThreadExecutor(self)
self.progressBarInit()
task = Task(
function=partial(
taxonomy.ensure_downloaded,
callback=methodinvoke(self, "advance", ())
)
)
task.resultReady.connect(self.initialize)
task.exceptionReady.connect(self._onInitializeError)
self.initfuture = self.executor.submit(task)
def Update(self):
"""
Update (recompute enriched pathways) the widget state.
"""
if not self.data:
return
self.error(0)
self.information(0)
# XXX: Check data in setData, do not even alow this to be executed if
# data has no genes
try:
genes = self.GeneNamesFromData(self.data)
except ValueError:
self.error(0, "Cannot extract gene names from input.")
genes = []
if not self.useAttrNames and any("," in gene for gene in genes):
genes = reduce(add, (split_and_strip(gene, ",")
for gene in genes),
[])
self.information(0,
"Separators detected in input gene names. "
"Assuming multiple genes per instance.")
self.queryGenes = genes
self.information(1)
reference = None
if self.useReference and self.refData:
reference = self.GeneNamesFromData(self.refData)
if not self.useAttrNames \
and any("," in gene for gene in reference):
reference = reduce(add, (split_and_strip(gene, ",")
for gene in reference),
[])
self.information(1,
"Separators detected in reference gene "
"names. Assuming multiple genes per "
"instance.")
org_code = self.SelectedOrganismCode()
def run_enrichment(org_code, genes, reference=None, progress=None):
org = kegg.KEGGOrganism(org_code)
if reference is None:
reference = org.get_genes()
# Map 'genes' and 'reference' sets to unique KEGG identifiers
unique_genes, _, _ = org.get_unique_gene_ids(set(genes))
unique_ref_genes, _, _ = org.get_unique_gene_ids(set(reference))
taxid = kegg.to_taxid(org.org_code)
# Map the taxid back to standard 'common' taxids
# (as used by 'geneset') if applicable
r_tax_map = dict((v, k) for k, v in
kegg.KEGGGenome.TAXID_MAP.items())
if taxid in r_tax_map:
taxid = r_tax_map[taxid]
# We use the kegg pathway gene sets provided by 'geneset' for
# the enrichment calculation.
# Ensure we are using the latest genesets
# TODO: ?? Is updating the index enough?
serverfiles.update(geneset.sfdomain, "index.pck")
kegg_gs_collections = geneset.collections(
(("KEGG", "pathways"), taxid)
)
pathways = pathway_enrichment(
kegg_gs_collections, unique_genes.keys(),
unique_ref_genes.keys(),
callback=progress
)
# Ensure that pathway entries are pre-cached for later use in the
# list/tree view
kegg_pathways = kegg.KEGGPathways()
kegg_pathways.pre_cache(
pathways.keys(), progress_callback=progress
)
return pathways, org, unique_genes, unique_ref_genes
self.progressBarInit()
self.setEnabled(False)
self.infoLabel.setText("Retrieving...\n")
progress = methodinvoke(self, "setProgress", (float,))
self._enrichTask = Task(
function=lambda:
run_enrichment(org_code, genes, reference, progress)
)
self._enrichTask.finished.connect(self._onEnrichTaskFinished)
self._executor.submit(self._enrichTask)
