Exemplo n.º 1
0
    def test_convert_to_mRNA_position_fail(self):
        """ Various attempts to break RNA position and make sure that error are caught """
        return
        tool = pybedtools.create_interval_from_list(
            "ENSMUSG1    51    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -    10    10"
            .split())
        location_dict = {
            "ENSMUSG1": {
                "strand": "-",
                "regions": [
                    (100, 150),
                    (25, 50),
                ]
            }
        }

        self.assertEqual(
            convert_to_mRNA_position(tool, location_dict).chrom, "none")

        tool = pybedtools.create_interval_from_list(
            "ENSMUSG1    51    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -    175    175"
            .split())

        self.assertEqual(
            convert_to_mRNA_position(tool, location_dict).chrom, "none")

        pybedtools.BedTool("chr1    x     y    ")
Exemplo n.º 2
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 def test_convert_to_mRNA_position_placement_split(self):    
     
     """
     
     Makes sure that lists of regions works for both positive and negative strands
     
     """
     
     return
     tool = pybedtools.create_interval_from_list("ENSMUSG1    125    127    ENSMUSG1_1_83;ENSMUSG1_6_83    0    +    125    125".split())
     location_dict = {"ENSMUSG1" : {"strand" : "+", "regions" : [(0, 50),
                                                                 (100, 150),
                                                                 ] 
                                    }
                      }
     
     correct_tool = pybedtools.create_interval_from_list("ENSMUSG1    75    77    ENSMUSG1_1_83;ENSMUSG1_6_83    0    +    125    125".split())
     self.assertEqual(convert_to_mRNA_position(tool, location_dict), correct_tool )
     
     tool = pybedtools.create_interval_from_list("ENSMUSG1    25    27    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -    25    25".split())
     location_dict = {"ENSMUSG1" : {"strand" : "-", "regions" : [(100, 150),
                                                                 (0, 50),
                                                                 ] 
                                    }
                      }
     
     correct_tool = pybedtools.create_interval_from_list("ENSMUSG1    73    75    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -    25    25".split())
     self.assertEqual(convert_to_mRNA_position(tool, location_dict), correct_tool)
Exemplo n.º 3
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 def test_convert_to_mRNA_position_placement(self):
     
     """
     
     Makes sure that the placement within a region or list of regions is correct
     
     """
     
     return
     interval = pybedtools.create_interval_from_list("ENSMUSG1    50    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    +    60    60".split())
     location_dict = {"ENSMUSG1" : {"strand" : "+", "regions" : [(0,100),
                                                                 ] 
                                    }
                      }
     
     correct_tool = pybedtools.create_interval_from_list("ENSMUSG1    50    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    +    60    60".split())
     self.assertEqual(convert_to_mRNA_position(interval, location_dict), correct_tool)
     
     interval = pybedtools.create_interval_from_list("ENSMUSG1    50    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -".split())
     location_dict = {"ENSMUSG1" : {"strand" : "-", "regions" : [(0,100),
                                                                 ] 
                                    }
                      }
     
     #individual_fraction, total_fraction
     correct_tool = pybedtools.create_interval_from_list("ENSMUSG1    40    50    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -".split())
     x =  convert_to_mRNA_position(interval, location_dict)
     print x
     self.assertEqual(x, correct_tool)
Exemplo n.º 4
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    def test_convert_to_mRNA_position_placement_split(self):
        """
        
        Makes sure that lists of regions works for both positive and negative strands
        
        """

        return
        tool = pybedtools.create_interval_from_list(
            "ENSMUSG1    125    127    ENSMUSG1_1_83;ENSMUSG1_6_83    0    +    125    125"
            .split())
        location_dict = {
            "ENSMUSG1": {
                "strand": "+",
                "regions": [
                    (0, 50),
                    (100, 150),
                ]
            }
        }

        correct_tool = pybedtools.create_interval_from_list(
            "ENSMUSG1    75    77    ENSMUSG1_1_83;ENSMUSG1_6_83    0    +    125    125"
            .split())
        self.assertEqual(convert_to_mRNA_position(tool, location_dict),
                         correct_tool)

        tool = pybedtools.create_interval_from_list(
            "ENSMUSG1    25    27    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -    25    25"
            .split())
        location_dict = {
            "ENSMUSG1": {
                "strand": "-",
                "regions": [
                    (100, 150),
                    (0, 50),
                ]
            }
        }

        correct_tool = pybedtools.create_interval_from_list(
            "ENSMUSG1    73    75    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -    25    25"
            .split())
        self.assertEqual(convert_to_mRNA_position(tool, location_dict),
                         correct_tool)
Exemplo n.º 5
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    def test_convert_to_mRNA_position_placement(self):
        """
        
        Makes sure that the placement within a region or list of regions is correct
        
        """

        return
        interval = pybedtools.create_interval_from_list(
            "ENSMUSG1    50    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    +    60    60"
            .split())
        location_dict = {
            "ENSMUSG1": {
                "strand": "+",
                "regions": [
                    (0, 100),
                ]
            }
        }

        correct_tool = pybedtools.create_interval_from_list(
            "ENSMUSG1    50    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    +    60    60"
            .split())
        self.assertEqual(convert_to_mRNA_position(interval, location_dict),
                         correct_tool)

        interval = pybedtools.create_interval_from_list(
            "ENSMUSG1    50    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -".
            split())
        location_dict = {
            "ENSMUSG1": {
                "strand": "-",
                "regions": [
                    (0, 100),
                ]
            }
        }

        #individual_fraction, total_fraction
        correct_tool = pybedtools.create_interval_from_list(
            "ENSMUSG1    40    50    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -".
            split())
        x = convert_to_mRNA_position(interval, location_dict)
        print x
        self.assertEqual(x, correct_tool)
Exemplo n.º 6
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 def test_convert_to_mRNA_position_fail(self):
     
     """ Various attempts to break RNA position and make sure that error are caught """
     return    
     tool = pybedtools.create_interval_from_list("ENSMUSG1    51    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -    10    10".split())
     location_dict = {"ENSMUSG1" : {"strand" : "-", "regions" : [(100, 150),
                                                                 (25,50),
                                                                 ] 
                                    }
                      }
     
     self.assertEqual(convert_to_mRNA_position(tool, location_dict).chrom, "none")
     
     tool = pybedtools.create_interval_from_list("ENSMUSG1    51    60    ENSMUSG1_1_83;ENSMUSG1_6_83    0    -    175    175".split())
     
     self.assertEqual(convert_to_mRNA_position(tool, location_dict).chrom, "none")
     
     pybedtools.BedTool("chr1    x     y    ")